Treatment for HPV-positive oropharyngeal cancer varies by facility type
Author: Mark Leiser Source: www.healio.com DALLAS — Treatment modality for HPV-positive oropharyngeal squamous cell carcinoma varied considerably by facility type, according to study results. The findings — presented at American Head & Neck Society Annual Meeting — showed academic hospitals more frequently utilized surgery instead of radiation therapy or chemoradiation therapy alone as the primary treatment modality for early- and late-stage cancers. The findings suggest a lack of standardized treatment regimens that prevent patients from receiving universal care independent of facility resources, Monica S. Trent, MD, first-year resident at University of California, Irvine, and colleagues concluded. “There are many different ways to treat HPV-positive oropharyngeal squamous cell carcinoma and, in order to try to determine the best treatment option, it is important to know who is offering what types of treatment at different centers,” Trent told Healio. “Our results show patients are being treated differently depending on where they present, and treatment is not standardized across different types of facilities.” Background and methods HPV-positive oropharyngeal squamous cell carcinoma is distinct from HPV-negative disease. It more frequently affects younger, healthier patients, and it is associated with improved prognosis and better historical survival outcomes after standard radiation and chemoradiation treatment protocols. The development of transoral robotic surgery offers an alternative upfront treatment option that could reduce short- and long-term morbidity without compromising oncologic outcomes, according to study background. However, due to the required resources and training needed for this modality, it has been offered primarily at academic medical centers. Trent and colleagues retrospectively [...]