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Follow doctor’s advice, have lesion removed

3. July 2009

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Source: www.cantonrep.com Author: Peter Gott, M.D. Patients’ question: In 1999, my dentist saw a discoloration on the floor of my mouth. He told me to see a doctor about it. The doctor talked me into having the spot surgically removed. A while back, I remember reading in your column that, 95 percent of the time, discolorations in the mouth [...]

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Invasion characteristics of oral tongue cancer: frequency of reporting and effect on survival in a population-based study

3. July 2009

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Source: Cancer, June 23, 2009 Author: Michael Goodman et al. Background: The 2000 College of American Pathologists (CAP) guidelines recommend that a characterization of carcinomas of the upper aerodigestive tract, including tongue cancer, should include depth of invasion (DI) and the presence of lymphovascular invasion (LVI) or perineural invasion (PNI). Methods: This study included patients who were diagnosed [...]

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The prognostic significance of histological features in oral squamous cell carcinoma

3. July 2009

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Source: J Oral Pathol Med, June 25, 2009 Authors: S R Larsen et al. Background: Different factors predict nodal metastasis, recurrence and survival in oral cancer. The aim was to assess the prognostic value of histological features related to the primary tumour. Methods: A total of 144 patients surgically treated at Odense University Hospital for oral cancer between [...]

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Improved oral tumor surgery reduces disfigurement

3. July 2009

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Source: taiwanjournal.nat.gov.tw Author: staff Traditional oral cancer surgeries involve entering the affected area through the lower lip, causing the patient’s lower lip to be disfigured in some cases. The patient may suffer from strange sensations as well as losing balance on both sides of the lower lip, making it impossible for them to fully purse their lips. A [...]

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Gran first in cancer study

3. July 2009

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Source: www.warwickdailynews.com.au Author:Toni Somes Stella Day would prefer not to have been written into the medical history books this week. She would also prefer not to have oral cancer. But yesterday the Stanthorpe grandmother willingly became Queensland’s first patient in a major international study looking to reduce cancer treatment side effects. “Even if it doesn’t help me directly, [...]

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Taste, odor intervention

3. July 2009

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Source: speech-language-pathology-audiology.advanceweb.com Author: staff Cancer and its therapies, including chemotherapy and radiotherapy, may directly alter and damage taste and odor perception, possibly leading to patient malnutrition, and in severe cases, significant morbidity, according to a Virginia Tech – Wake Forest University Comprehensive Cancer Center compilation of various existing studies [Journal of Supportive Oncology, 7(2): 58-65]. One of the [...]

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New products ingenious or insidious?

3. July 2009

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Source: www.mailtribune.com Author: John Darling The use of smokeless tobacco in Jackson County has steadily risen in recent years among teens and adults — and now, officials fear the introduction earlier this year of new, candy-flavored “dissolvable tobacco” lozenges will make matters worse. Called Orbs, the pellets, which look and taste like breath mints, contain as much nicotine [...]

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New biomarker method could increase the number of diagnostic tests for cancer

1. July 2009

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Source: news.biocompare.com Author: staff A team of researchers has demonstrated that a new method for detecting and quantifying protein biomarkers in body fluids may ultimately make it possible to screen multiple biomarkers in hundreds of patient samples, thus ensuring that only the strongest biomarker candidates will advance down the development pipeline. The researchers have developed a method [...]

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Is it really about time? Overcoming the real barriers to complete oral cancer screening

30. June 2009

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Source: www.dentalofficemag.com Author: Jonathan A. Bregman, DDS, FAGD From coast to coast the same answer: As I tour the country presenting programs on early oral cancer detection, I ask the same question to all of my attendees: “What do you think is the main reason that dentists give for not doing a complete oral cancer examination?” The unanimous response [...]

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Researchers pinpoint a new enemy for tumor-suppressor P53

30. June 2009

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Source: biocompare.com Author: staff Researchers at The University of Texas M. D. Anderson Cancer Center have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer cells. The new protein, called Trim24, feeds p53 to a protein-shredding complex known as the proteasome by attaching targeting molecules called [...]

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