HPV vaccine still fights for acceptance, despite benefits

Source: www.floydcountytimes.com Author: Tom Collins Last month, actor Michael Douglas caused a stir in the media when he suggested his throat cancer might have been caused by oral sex. He could be right. Although smoking and alcohol use have long been regarded as the key risk factors, new research indicates that HPV, a sexually transmitted virus, is now the leading cause of mouth and throat cancers in the United States. But there’s an important take-away message to this story: Some cancers caused by HPV can be prevented easily, with a simple series of three vaccinations. Since 2000, scientists have known that certain strains of HPV are responsible for nearly all cervical cancer in women. But newer studies indicate HPV can cause other types of cancer as well. Recent findings have also linked HPV to oral, head/neck, anal, vaginal, vulvar and penile cancers, and even some cases of lung cancer. About half of all Americans will become infected with HPV at least once during their lifetime. The most common visible symptom of an HPV infection is genital warts, although the majority of HPV infections do not display symptoms. That’s why the Centers for Disease Control and Prevention recommends that boys and girls alike be vaccinated against HPV. Ideally, they should be vaccinated between the ages of 11 and 12. Vaccination can be initiated as early as age 9, and the U.S. Food and Drug Administration has approved the vaccine to be given up to age 26. Yet HPV vaccination rates remain [...]

Teen HPV Rates Were Cut In Half After The Vaccine Went Public

Source ThinkProgress.orgBy Annie-Rose Strasser Published Jun 19, 2013 at 2:35 pm   Following the 2006 introduction of a vaccine against cancer-causing human papillomavirus, rates of HPV in teen girls have plummeted to nearly half, a new study found on Wednesday. The Journal of Infectious Diseases reports that HPV infection in girls ages 14 to 19 dropped from 11.5 percent for the years 2003-2006 to 5.1 percent for 2007-2010. Since HPV can lead to cervical cancer, the results also could herald a drop in cancer rates for girls in this age range, too. The study illustrates a great advancement in public health, but it also underlines the consequences for those huge numbers of women and girls who are still not getting their vaccinations; in 2011, only 35 percent of girls ages 13-17 received all three shots in the vaccination series, and only 30 percent of women ages 19-26 had received the vaccine. Fear-mongering and conspiracy theories over the side effects of the HPV vaccine are a major reason that inoculation rates are so low. While the Centers for Disease control have deemed the shots safe, and especially effective for young girls, 16 percent of parents report not letting their children get the shots for fear of side effects. In fact, incidents of cancer from HPV are rising in the U.S., and the CDC says rates of inoculation are “unacceptably low.” These dangerous theories are fueled by conservatives like Rep. Michele Bachmann (R-MN), who campaigned on her insistence that HPV vaccines cause “mental [...]

2013-06-20T11:53:25-07:00June, 2013|Oral Cancer News|

Why HPV vaccination makes a difference against cancer

Source: www.cbsnews.com Author: Michelle Castillo Michael Douglas' frank discussion about the human papillomavirus (HPV) and oral cancer has put a spotlight on the dangers of the sexually transmitted virus. While using a condom may reduce risk for HPV, doctors are reminding people that the best way to protect oneself from the disease that can potentially lead to cancer is to get vaccinated at an early age and, if possible, go for routine screenings. HPV is a group of more than 100 very common viruses, about 40 of which can be transmitted sexually, according to the U.S. Department of Health and Human Services Office on Women's Health. Approximately 79 million Americans are currently infected with an HPV strain, the Centers for Disease Control and Prevention reports, and nearly all sexually active men and women will get one type of sexually transmitted HPV in their lifetime. Specifically, 20 million people in the U.S. between the ages of 15 to 49 are infected with a genital HPV at any given time, and about half of men and women can expect to be infected with genital HPV in their lifetime. "HPV is ubiquitous in our population," Dr. Lori Wirth, medical director of the Center for Head and Neck Cancers center at Massachusetts General Hospital in Boston, explained to CBSNews.com. "Anyone who has led a normal sex life will get HPV, and develop antibodies to the virus. But, a minority of people who have contact with the virus who don't effectively clear the virus from [...]

Health Experts Praise Michael Douglas For His Oral Cancer Revelation

June 3rd, 2013 7:20pm EDTSource: starpulse.com    Health experts have commended Michael Douglas for speaking out about link between throat cancer and oral sex. The 68 year-old actor, who endured a six-month battle with the illness, hit headlines over the weekend when he voiced his belief that his cancer was caused by HPV, the human papillomavirus, which can be contracted through oral sex. The Behind The Candelabra star told Britain's The Guardian newspaper, "Without wanting to get too specific, this particular cancer is caused by HPV, which actually comes about from cunnilingus... I mean, I did worry if the stress caused by my son's incarceration didn't help trigger it. But yeah, it's a sexually transmitted disease that causes cancer. And if you have it, cunnilingus is also the best cure for it." Douglas' frank admission has now won him praise from Brian Hill, executive director of Oral Cancer Foundation, who tells the New York Post, "I'm really quite proud of Michael saying this. This (oral sex) is not an aberrant sexual behavior. But the willingness to talk about this openly can be difficult." The actor recorded a public service announcement for the Oral Cancer Foundation last year.   *This news story was resourced by the Oral Cancer Foundation, and vetted for appropriateness and accuracy.  

2013-06-10T11:43:06-07:00June, 2013|OCF In The News|

Fact check: Michael Douglas on HPV and throat cancer

Source: www.huffingtonpost.com Author: Meredith Melnick A Michael Douglas interview in The Guardian caused waves when the publication reported that the "Behind the Candelabra" star revealed HPV, the human papilloma virus, to be the cause of his stage-4 throat cancer diagnosis in 2010. "Without wanting to get too specific, this particular cancer is caused by HPV, which actually comes about from cunnilingus," Douglas allegedly told The Guardian. Douglas, through his publicist, has said that the statement was misinterpreted: He wasn't saying that his cancer was caused by the sexually transmitted disease -- merely that many cancers like his are HPV-positive. As The Daily Beast points out, there is scant research evidence to directly link the act of cunnilingus with HPV infection. But regardless of the details of his own cancer, the actor is right about one thing: A growing majority of oral cancer cases are caused by HPV. While most strains of HPV clear up on their own, the sexually transmitted disease is responsible for an array of cancers. As Douglas describes, it's true that oral sex is an avenue through which a person can contract HPV and especially the strains, HPV-18 and HPV-16, the latter of which is responsible for half of oral cancer cases, according to the National Cancer Institute. HPV-16, HPV-18 and some less-common strains can also cause cancers of the cervix, vagina, vulva, anus and penis. Douglas' experience follows trends in cancer diagnosis, according to a January report from the American Cancer Society, which found a rise [...]

Michael Douglas: Oral sex gave me cancer

By DAVID K. LISource: NewYork PostLast Updated: 11:31 AM, June 3, 2013Posted: 8:49 PM, June 2, 2013 Michael Douglas has made a jaw-dropping revelation about his throat cancer: He didn’t contract it from smoking or drinking — but from oral sex. The Oscar-winning Hollywood star set tongues wagging after he told The Guardian newspaper that he contracted HPV, or human papillomavirus, through a sex act and it developed into cancer. “Without wanting to get too specific, this particular cancer is caused by HPV, which actually comes about from cunnilingus,” he told the British newspaper in an interview published yesterday. After Douglas was diagnosed with the life-threatening illness in 2010, he said on “Late Show with David Letterman” that the kind of cancer he had was caused by smoking and drinking.  Ghetty Images   Actor Michael Douglas said a virus from oral sex, not booze and cigarettes, gave him throat cancer. In yesterday’s interview, the 68-year-old actor speculated that his son Cameron’s legal woes may have borne some responsibility, too. “I did worry if the stress caused by my son’s incarceration didn’t help trigger it,” the “Wall Street” actor said of Cameron Douglas, who is serving 10 years in a federal prison for heroin possession and distribution. “But, yeah, it’s a sexually transmitted disease that causes [the] cancer.” A cancer-awareness advocate hailed Douglas for his blunt talk. “I’m really quite proud of Michael saying this,” Brian Hill, executive director of the Oral Cancer Foundation, told The Post yesterday. “This [oral sex] is [...]

2013-06-03T09:50:47-07:00June, 2013|OCF In The News, Oral Cancer News|

When a virus causes cancer, surgical robot can help

Source: www.bizjournals.com Author: James Ritchie Dr. Keith Wilson finds robotic surgery to be a good approach for removing tumors growing deep in the throat, as I recently reported. As it turns out, such tumors are often part of an alarming trend. They’re often caused by the sexually transmitted human papillomavirus, also known as HPV. In decades gone by, oral cancer was almost always associated with tobacco and alcohol use. It was typically a disease of old men. No more. Many of Wilson’s patients are nonsmokers and very light drinkers. “I can’t tell you how surprised people get,” said Wilson, who is chief of staff at University of Cincinnati Medical Center. “We’re seeing younger, more affluent and more highly educated patients.” High-risk HPVs cause virtually all cervical cancers. They have in recent years been implicated in oropharyngeal cancers. The oropharynx is the middle part of the throat, including the soft palate, the base of the tongue and the tonsils. About 63 percent of oropharyngeal cancers, or 11,000 cases per year, are associated with HPV infection, according to the American Dental Association. They’re frequently under age 50. Fortunately for such patients, HPV-associated oropharyngeal cancers have a better prognosis than those with other causes. Wilson said that cure rates can approach 90 percent. The da Vinci surgical robot is an effective tool for removing them, he said, because its long, joined arms can go where a surgeon’s hands can’t. But the machines, made by Sunnyvale, Calif.-based Intuitive Surgical Inc., are gaining some criticism. [...]

Dose of reality: HPV is epidemic, which is odd since it is largely preventable

Source: www.sciencenews.org Author: Nathan Seppa There are two vaccines that guard against human papilloma­virus, and they are in rare company among medical inventions — the vaccines prevent cancer. Only the hepatitis B vaccine can make the same claim. Cancer-causing HPV can trigger abnormal cell growth on the cervix, and cervical cancer still kills up to 4,000 U.S. women each year. The virus is also implicated in cancers occurring in the anus and the throat. All told, according to a 2011 study, 29 percent of sexually active U.S. girls and women carry a potentially cancer-causing HPV infection. Preteen and adolescent girls and boys are priority groups for vaccines that prevent human papillomavirus infection.© Jessica Rinaldi/Reuters/Corbis Back in 2006 and 2009, when the HPV vaccines Gardasil and Cervarix came onto the market, health officials dreamed of halting the spread of HPV, which is sexually transmitted, in a single generation. Scientists call such blanket coverage herd immunity — in which a pathogen gets vaccinated into oblivion, becoming so rare that even unvaccinated people are protected. With such heady potential, Gardasil, developed by Merck, and Cervarix, created by GlaxoSmithKline, should be an easy sell. They rev up a potent immunity against HPV 16 and 18, the two types of the virus that account for most cases of cervical cancer. Gardasil also prevents most genital warts. The immunity the vaccines provide is many-fold better than the weak protection engendered by a run-in with the virus itself, and since approval, both vaccines have proven [...]

Researchers design drug to block incidence of head, neck cancer caused by HPV virus

Source: www.news-medical.net Researchers have discovered a new mechanism by which the human papilloma virus (HPV) causes head and neck cancer, and they have designed a drug to block that mechanism. Though further research is needed, the new agent might offer a safer treatment for these tumors when combined with a tapered dose of standard chemotherapy. HPV-positive head and neck cancer has become three times more common since the 1970s, and it could reach epidemic levels in the future, say researchers at the Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) who led the study. "We believe these findings will help meet the real need for more effective and safer therapy for a growing number of HPV-positive head and neck cancer patients," says principal investigator Dr. Quintin Pan, associate professor of otolaryngology at the OSUCCC - James. The study was published in the journal Oncogene. The research, which mainly used head and neck cancer cells, shows that a protein produced by the virus blocks a protein made by the host cell. The cell protein, called p300, regulates a gene called p53. This gene both controls cell division and protects the body against cancer by causing cells to die before they become malignant.By blocking the cell protein, HPV forces the host cell to live instead of die and to proliferate and form tumors. The prospective new drug, called CH1iB, prevents the viral protein from binding with the cell protein. This restores [...]

HPV linked to certain lung cancers; is oral sex to blame?

Source: www.medicaldaily.com Author: Jonathan Weiss By now, it's a given that smoking causes lung cancer. The American Lung Association reports that 80 to 90 percent of all cases of lung cancer are smoking-related. The remaining 10 to 20 percent, though, has been more of a mystery — until now. A new line of research has implicated thye sexually transmitted infection human papillomavirus, or HPV, in lung cancers that were found in non-smokers. HPV is the leading cause of all cervical cancer cases in the world. It's a well-known disease that's gottena lot of press in recent years; an effective vaccine was recently developed that can prevent the viral infection and subsequent cervical cancer development. Whether or not the vaccine should be required for teenage girls has become a hot-button political issue. Adding fuel to the fire, a research team from the Fox Chase Cancer Center recently looked at tissue samples from lung cancer patients who had no history of smoking and saw that close to 6 percent showed evidence that they had been driven by HPV infection. Four out of 36 lung samples had signs of infection from two strains of HPV known to cause cancer. Looking more closely at the two samples infected by one strain of HPV, Dr. Ranee Mehra, MD, attending physician in medical oncology at Fox Chase and her team saw signs the virus had integrated into the tumor's DNA — which is even more suggestive that the infection had caused the tumor in the first [...]

Go to Top