nitrosamines – Oral Cancer News

Levels of cancer-causing chemicals in smokeless tobacco products influence carcinogen exposure

Source: www.healthcanal.com Author: staff Higher levels of cancer-causing chemicals called tobacco-specific nitrosamines in smokeless tobacco products led to greater exposure to these carcinogens even after taking into account how much or how long the product was used, according to a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research. “Our results show that although the pattern of tobacco use—for example, amount of dip and number of dips—can influence the level of smokeless tobacco users’ exposure to tobacco-specific nitrosamines, the actual amount of these chemicals in the products also makes a significant difference,” said Dorothy K. Hatsukami, PhD, the Forster Family professor in cancer prevention in the Department of Psychiatry at the University of Minnesota in Minneapolis. “The majority of smokeless tobacco users in the United States are not aware of the levels of cancer-causing chemicals in their smokeless tobacco products or of the tremendous variability in the levels of these chemicals across brands sold in this country,” continued Hatsukami. “At a minimum, the FDA [U.S. Food and Drug Administration] should provide smokeless tobacco consumers information about the different levels of cancer-causing chemicals in different brands of smokeless tobacco and, ideally, require levels of tobacco-specific nitrosamines be substantially reduced, if not eliminated, in all products. Levels of these chemicals in smokeless tobacco products could be readily reduced by changing manufacturing practices.” Levels of exposure to tobacco-specific nitrosamines are associated with disease risk, according to Hatsukami. Prior studies have shown that smokeless tobacco users in the [...]

Oral Cancer Foundation News Team - A2014-12-25T12:37:53-07:00December, 2014|Oral Cancer News|

Most youth who use smokeless tobacco are smokers, too

By Anne HardingNEW YORK | Thu Aug 8, 2013 5:17pm EDTSOURCE: bit.ly/13INoAt Pediatrics, online August 5, 2013. (Reuters Health) - Most young people in the U.S. who use newer smokeless tobacco products are smoking cigarettes too, according to new research. "These findings are troubling, but not surprising, as tobacco companies spend huge sums to market smokeless tobacco in ways that entice kids to start and encourage dual use of cigarettes and smokeless tobacco," Vince Willmore, vice president of communications at the Campaign for Tobacco-Free Kids, a Washington, D.C.-based advocacy organization, told Reuters Health in an email. "From 1998 to 2011, total marketing expenditures for smokeless tobacco increased by 210 percent - from $145.5 million to $451.7 million a year, according to the Federal Trade Commission," he added. Swedish-style "snus," introduced to the U.S. in 2006, and dissolvable tobacco products, introduced in 2008, are arguably less harmful than conventional chewing tobacco because they contain fewer nitrosamines, and have been promoted as safer alternatives. But public health experts have been concerned that these products could serve as a "gateway drug" to use of conventional smokeless tobacco and to cigarette smoking. To better understand the prevalence of smokeless tobacco use among young people, Dr. Gregory Connolly of the Harvard School of Public Health in Boston and his colleagues looked at data from the 2011 National Youth Tobacco Survey, which included nearly 19,000 sixth- to 12th-graders from across the country. Overall, the researchers found, 5.6 percent of young people reported using any type of [...]

Charlotte Parker2013-08-09T12:33:36-07:00August, 2013|Oral Cancer News|

Are lozenges and other smokeless products safer alternatives to smoking?

Source: Pennsylvania's Fox News Tobacco company rep David Howard waxes enthusiastic when he talks about a new product his employer, R.J. Reynolds Tobacco Co., has developed: a pellet of finely cured tobacco, binders and flavoring that dissolves in the mouth in 10 minutes. Under test market in two U.S. cities — Denver and Charlotte, N.C. — Camel Orbs will join two dissolvable tobacco lozenges already on the market if it graduates to broader distribution. And Howard is optimistic it will. "These products provide smokers with an option to enjoy the pleasure of nicotine without bothering others," Howard said. "No secondhand smoke. No spitting. No cigarette butt." Dissolvable tobacco consists of small pieces of compressed, finely ground tobacco powder, binders and flavorings that are shaped into pellets, sticks or strips. When placed in the mouth, they dissolve within minutes, providing a nicotine hit. The tobacco industry says that the products contain far fewer cancer-causing chemicals such as tobacco-specific nitrosamines and are a "harm reduction" strategy that, like electronic cigarettes, might help people turn to less risky tobacco habits or eventually quit smoking. But public health officials and anti-smoking advocates fear that the products will help initiate a new generation of smokers. The flavoring and packaging appeal to children, they argue, and teenagers will gravitate toward a product they can easily hide. On Thursday, the Food and Drug Administration will take up the issue with an advisory committee hearing on the effect of dissolvable tobacco products on public health. "Tobacco companies are [...]

Oral Cancer Foundation News Team - A2011-07-22T10:44:37-07:00July, 2011|Oral Cancer News|

New snuff low in carcinogens, Virginia company says

Source: www2.journalnow.com Author: Richard Craver A small tobacco manufacturer in Richmond, Va., said Tuesday that it has developed a moist-snuff product that has the lowest levels of carcinogens — in this case nitrosamines — in the marketplace. That includes "99 percent lower than the levels found in conventional American moist snuffs, such as Copenhagen or Skoal, and 90 percent less than the level found in current snus products," the company said. Star Scientific Inc. plans to apply soon to the Food and Drug Administration for permission to market the product, part of its Stonewall brand, as "modified risk" under the Family Smoking Prevention and Tobacco Control Act of 2009. That act gave the FDA the regulatory control over new tobacco products. Star applied last year to market its Ariva and Stonewell lozenges as modified risk. "Our company's belief and hope is that the FDA will give a robust look at the science of our application and other reduced-risk applications," said Sara Machir, the vice president of communications and investor relations for Star. The request is likely to stoke further debate between two sets of anti-smoking groups. One set says smokeless tobacco serves as gateway products for teenagers to cigarettes and discourages users from quitting. The other set says the products are a way to reduce the risk of tobacco use compared with cigarettes. Scott Ballin, the past chairman of the Coalition on Smoking or Health, said the debate "is more about competition, market share and profits than it is about [...]

Oral Cancer Foundation News Team - A2011-01-07T11:41:27-07:00January, 2011|Oral Cancer News|

In India, an epidemic of oral cancer

Source: www.businessweek.com Author: Adi Narayan Safiq Shaikh was 13 when he began chewing a blend of tobacco and spices that jolted him awake whenever his job at a textile loom got too dreary. Five years later, doctors in Mumbai lopped off his tongue to halt the cancer spreading through his mouth. Shaikh believed the fragrant, granular mixture he chewed, known in India as gutka, was harmless, so at first he ignored the milky lump growing inside his mouth. Now he is one of about 200,000 Indians diagnosed with a tobacco-related malignancy this year, says his surgeon, Dr. Pankaj Chaturvedi, who works at Tata Memorial Hospital in Mumbai. Chaturvedi says a group of entrepreneurs known as "gutka barons" bear much of the blame for this epidemic by mass marketing a mix of tobacco and areca nut for 1 rupee (2 cents) a pack on street corners across India. Sales of chewing tobacco in India, worth 210.3 billion rupees ($4.6 billion) in 2004, are on track to double by 2014, according to Datamonitor, the international research firm. Before, a traditional chewing mixture, known as paan, came with or without tobacco. It had to be handmade, was messy to carry around, and lacked modern packaging. "Now you have an industrial version of a traditional thing" spurring demand, says Chaturvedi. On Dec. 7, India's Supreme Court banned the sale of tobacco products in plastic wrappers as of Mar. 1, citing harm to public health and environmental damage from improper disposal of the packets. The [...]

Oral Cancer Foundation News Team - A2010-12-30T16:03:01-07:00December, 2010|Oral Cancer News|

FDA analysis finds toxic substances in electronic cigarettes

Source: www.rwjf.org/publichealth Author: staff A preliminary analysis by the Food and Drug Administration (FDA) indicates that electronic cigarettes contain traces of toxic substances and carcinogens, contradicting manufacturers' claims that the products are safe alternatives to tobacco, the New York Times reports. According to manufacturers, the battery-powered devices, which produce a vapor that users inhale, contain little more than water, nicotine and propylene glycol, which is used in theatrical performances to create artificial smoke. However, an FDA analysis of the ingredients in two leading brands of electronic cigarettes found that some had detectable levels of nitrosamines, tobacco-specific compounds known to cause cancer. In addition, one Smoking Everywhere cartridge contained diethlyene glycol, a common ingredient in antifreeze that contributed to the death of hundreds of individuals worldwide after it was incorrectly used as a substitute for glycerin in toothpaste. According to the FDA's principal commissioner, the effect of inhaling diethlyene glycol and other carcinogens through electronic cigarettes on the human body remains unknown. The study also highlighted several quality control issues with the electronic cigarettes, which are manufactured in China. For example, nicotine levels varied among cartridges with labels that claimed to contain identical amounts of nicotine, and some cartridges claiming to be nicotine free did contain nicotine. Calling the products drug delivery devices, the FDA says electronic cigarettes should not be allowed in the United States and has rejected approximately 50 shipments at the border since summer 2008. However, vendors in malls nationwide and online continue to sell electronic cigarettes, which [...]

Oral Cancer Foundation News Team - A2010-07-20T06:49:17-07:00July, 2010|Oral Cancer News|

New tobacco product prompts concerns… No it’s not Marlboro…

Source: www.us-marlboro.com Author: staff Sweden brought us meatballs, the Nobel prize, Ikea, the Saab and the Volvo. But the country’s latest mark on the U.S. is not so benign: an oral tobacco product known as snus. The moist tobacco, which comes in a tea-bag-style pouch that goes under the upper lip, has public health experts divided. Some say snus (rhymes with loose) could save scores of lives if smokers switch to it, because the product contains far fewer carcinogens than do cigarettes, chew and snuff. Critics, though, say snus will only increase the number of people addicted to nicotine and poses a serious threat to anti-tobacco efforts. They say it could create a new crop of young nicotine addicts, while smokers could just as easily supplement their habit rather than substitute one for the other.Some Americans have been using snus by ordering it online or buying it in U.S. test markets, but R.J. Reynolds Tobacco didn’t release Camel Snus nationally until a few weeks ago, the first and only major tobacco company to do so. Philip Morris is selling Marlboro Snus in test markets. In Sweden, nearly a fifth of men in 2007 said they used snus daily, compared with 12 percent who smoke, according to Swedish Match, the country’s largest snus producer. The trend doesn’t hold for Swedish women: just 4 percent use snus and 16 percent smoke. Sweden also has fewer cases of lung cancer than the rest of Europe. Advocates of snus say it deserves at least [...]

Oral Cancer Foundation News Team - A2009-10-06T13:05:32-07:00October, 2009|Oral Cancer News|

Tobacco road takes a turn to the smokeless

Source: online.wsj.com Author: Kevin Helliker About 18 months ago, Russell Stevens gave up cigarettes and took up a new habit -- placing between his lip and gum a tiny pouch of smokeless tobacco called Camel Snus. The 26-year-old Kentuckian says it satisfies his craving for nicotine while exposing him to far fewer risks than did smoking. Like Mr. Stevens, more Americans are continuing to give up smoking, helping to push cigarette consumption down about 3% each year. To help kick the habit, many smokers turn to safer sources of nicotine -- the addictive but non-carcinogenic ingredient in cigarettes -- such as nicotine gum, patches or lozenges. But one method that has been gaining ground as a safer alternative to cigarettes -- smokeless tobacco -- remains controversial. A decades-old federal law requires smokeless tobacco to carry a label warning that it is not a safe alternative to cigarettes. The perils include possibly increased risk for certain cancers and cardiovascular disease. And U.S. public-health officials note that no clinical trials have been conducted showing that smokeless tobacco is an effective quitting aid. Adding to the controversy: Some of the biggest cigarette makers are jumping into the non-combustible market. "There is no evidence that smokers will switch to smokeless tobacco products and give up smoking," Michael Thun, vice president of epidemiology for the American Cancer Society, said in a recent article in the journal CA. Still, popular brands of smokeless tobacco generally contain far fewer carcinogens than do cigarettes, although some studies indicate [...]

Oral Cancer Foundation News Team - A2009-01-27T15:06:01-07:00January, 2009|Oral Cancer News|