vaccine – Page 7 – Oral Cancer News

First long-term study on HPV claims the vaccine is 100% effective at protecting men from cancer caused by the STI

Source: www.dailymail.co.uk Author: Cheyenne Roundtree The first long-term study conducted into the HPV vaccine confirm it is almost 100 percent effective at protecting men from developing oral cancer. The treatment was approved to the market in 2006 to prevent women from getting cervical cancer but experts haven't been able to fully examine its effect over time. Now, the results are in from a three-year study on the effects - the longest investigation ever on HPV. It confirmed that there was no trace of cancer-linked strains of HPV among men who received the vaccine - whereas two percent of untreated men had a potentially cancerous strain. Another study, also released today, found the jab makes it next to impossible for vaccinated children to develop genital warts from the STI in their late teens and 20s. Despite a multitude of interest and research, these are the first substantial studies to confirm the vaccine's ability to protect people from the STI and diseases that can stem from it. Human papillomavirus (HPV) is the most common sexually-transmitted disease in the US, with approximately 80 million people currently infected. Although most infections disappear on their own, without even displaying symptoms, some strains can lead to genital warts and even cancers, including prostate, throat, head and neck, rectum and cervical cancer. Approximately 28,000 cases of cancer caused by HPV are diagnosed annually - most of which would have preventable with the vaccine, the CDC says. The vaccine was first introduced with the main goal to prevent [...]

Oral Cancer Foundation News Team - A2017-05-22T07:38:53-07:00May, 2017|Oral Cancer News|

HPV vaccine; cancer prevention

Source: www.nujournal.com Author: staff Human papillomavirus (HPV) is a sexually transmitted infection, of several strains, most associated with cervical cancers. The virus is so common that nearly all males and females have been infected at some time in their life. One in four is currently infected in the nation. Signs and symptoms of HPV are variable. Most will recover from the virus within two years without ever knowing they were infected, making HPV easy to spread. Occasionally, the virus lasts much longer in the body which can cause cells to change and lead to cancer. Fortunately, we have a vaccine to prevent cancer caused by HPV. The Food and Drug Administration (FDA) has approved three vaccines for HPV; Cervarix, Gardasil, and Gardasil 9. These vaccines are tested and proven to be safe and effective. Prevention is important with HPV. The vaccine should be administered before exposure to the virus for stronger protection against cervical, vaginal, vulvar, penile, and some mouth or throat cancers. (Gardasil and Gardasil 9 also prevent genital warts and anal cancer.) The best age to obtain maximum potential of the vaccine is at 11 or 12 years old. At this age, the body’s immune system is the most receptive to the vaccination’s virus-like particles and the body produces higher amounts of antibodies in defense, protecting the adolescent for his or her future. Both girls and boys should get the HPV vaccine. For ages 9-14, two doses – six to twelve months apart, are recommended. For 15-26 year [...]

Oral Cancer Foundation News Team - A2017-04-17T13:13:58-07:00April, 2017|Oral Cancer News|

More than 1 In 5 Americans have a potentially cancer-causing HPV infection

Source: www.huffingtonpost.com Author: Erin Schumaker More than 42 percent of adults in the United States are infected with human papillomavirus ― and nearly 23 percent are infected with a high-risk strand of the virus that can cause cancer, according to a report published by the National Center for Health Statistics on Thursday. “We tend to overlook the fact that 20 percent of us are carrying the virus that can cause cancer (indluding oral cancer - OCF news editor),” Geraldine McQuillan, lead author of the report and an epidemiologist at the U.S. Centers for Disease Control and Prevention, told The Washington Post. “People really need to realize that this is a serious concern.” The report, which examined U.S. adults ages 18 to 59, marks the first time the CDC has recorded HPV rates in men as well as women. There is no FDA-approved HPV test for men, but the CDC developed its own test for the research. “We did penile swabs which we tested for HPV DNA,” McQuillan told The Huffington Post. HPV is the most common sexually transmitted disease in the country, and nearly every sexually active American will be exposed to it by their early 20s. Although 90 percent of HPV infections clear the body within two years, that’s not always the case. High-risk strains are linked to cervix, vaginal, penile, anus and throat cancers, as well as genital warts. In fact, two high-risk strains, HPV-16 and -18, cause nearly all cervical cancer cases. Not all Americans have the [...]

Oral Cancer Foundation News Team - A2017-04-08T09:29:49-07:00April, 2017|Oral Cancer News|

Game changer’ HPV vaccine is now just 2 shots – not 3 – in bid to simplify

Source: www.dailymail.co.uk Author: Mary Kekatos for dailymail.com HPV vaccines will now be administered in two doses instead of three The virus is the most common sexually transmitted infection in the US But only 28% of boys and 42% of girls received the advised three doses in 2015 Doctors hope the new guidelines increase the number of kids who get the shot The HPV vaccine will now be administered in two doses instead of three, new guidelines declare. The new rules, published on Monday, come after years of campaigns from cancer experts insisting an easier schedule would encourage more people to protect themselves from the sexually-transmitted infection. Human papillomavirus (or, HPV) is the most common STI in the United States, affecting around 79 million people. It has been linked to numerous cancers - including prostate, throat, head and neck, rectum and cervical cancer. Experts claim more widespread vaccine coverage of middle school children could prevent 28,000 cancer diagnoses a year. Currently, fewer than half the children eligible for the vaccine - given out as three doses over six months - are covered. Experts blame the lengthy, arduous schedule. The American Cancer Society today endorsed the updated recommendations, which were released by the Advisory Committee on Immunization Practices (ACIP). Dr Debbie Saslow, Senior Director, HPV Related and Women's Cancers for the American Cancer Society, said: 'In the past several years, studies have shown the vaccine is even more effective than expected. 'This new two-dose regimen is easier to follow, and we now [...]

Oral Cancer Foundation News Team - A2017-02-08T18:46:13-07:00February, 2017|Oral Cancer News|

NCI-Designated Cancer Centers Issue Statement in Support of New CDC Recommendations on HPV Vaccination

Source: The ASCO Post Posted: 1/11/2017 The 69 National Cancer Institute (NCI)-designated cancer centers have issued a joint statement in support of recently revised recommendations from the Centers for Disease Control and Prevention (CDC) to improve national vaccination rates for human papillomavirus (HPV). According to the CDC, incidence rates of HPV-associated cancers have continued to rise, with approximately 39,000 new HPV-associated cancers now diagnosed each year in the United States. Although HPV vaccines can prevent the majority of cervical, anal, oropharyngeal, and other genital cancers, vaccination rates remain low across the United States, with just 41.9% of girls and 28.1% of boys completing the recommended vaccine series. New Recommendations The new guidelines from the CDC recommend that children under age 15 should receive 2 doses of the 9-valent HPV vaccine at least 6 months apart. Adolescents and young adults older than 14 should continue to complete the 3-dose series. Research shows there are a number of barriers to overcome to improve vaccination rates, including a lack of strong recommendations from physicians and parents not understanding that this vaccine protects against several types of cancer. In an effort to overcome these barriers, NCI-designated cancer centers have organized a continuing series of national summits to share new research, discuss best practices, and identify collective action toward improving vaccination rates. The original joint statement, published in January 2016, was the major recommendation from a summit hosted at The University of Texas MD Anderson Cancer in November 2015, which brought together experts from the [...]

Charlotte Parker2017-01-11T16:57:19-07:00January, 2017|Oral Cancer News|

Feds, cancer centers aim to boost HPV vaccinations

Source: www.dispatch.com Author: JoAnne Viviano Faced with getting her daughter the HPV vaccine, which helps protect against cervical and other cancers, Anaraquel Sanguinetti paused. The human papillomavirus is spread through sexual contact, and the Westerville mom didn’t want her now-18-year-old daughter to think she was promoting promiscuity. So Sanguinetti did some research. And she had a long talk with her daughter, and another with her doctor. In the end, daughter Celine got the vaccine last year. “We are discovering every day new reasons why people obtain cancer, so it’s just another added layer of protection for my daughter for her future, because you just never know,” Sanguetti said. “ I didn’t want to have a regret.” Sanguetti is in the minority. Though vaccinating against HPV is recommended by the Centers for Disease Control and Prevention, and countless cancer centers and health-care providers, most children in the United States have not been vaccinated against HPV. Calling that “a serious public health threat,” dozens of cancer centers released a joint statement on Wednesday urging more parents and pediatricians to get onboard. The statement endorses the CDC’s recent revisions to its HPV vaccine recommendations. Vaccinating, the statement says, could help prevent the nearly 40,000 cases of HPV-associated cancers diagnosed in the United States each year. “Get the HPV vaccine for your child so they don’t have to hear those words: ‘You have cancer,’ “ said Electra Paskett, co-leader of cancer control at Ohio State University’s Comprehensive Cancer Center, which is among the institutions [...]

Oral Cancer Foundation News Team - A2017-01-11T09:30:48-07:00January, 2017|Oral Cancer News|

The startling rise in oral cancer in men, and what it says about our changing sexual habits

Source: www.washingtonpost.com Author: Ariana Eunjung Cha Oral cancer is on the rise in American men, with health insurance claims for the condition jumping 61 percent from 2011 to 2015, according to a new analysis. The most dramatic increases were in throat cancer and tongue cancer, and the data show that claims were nearly three times as common in men as in women during that same period with a split of 74 percent to 26 percent. The startling numbers — published in a report on Tuesday by FAIR Health an independent nonprofit — are based on a database of more than 21 billion privately billed medical and dental claims. They illustrate both the cascading effect of human papillomavirus (HPV) in the United States and our changing sexual practices. The American Cancer Society estimates that nearly 50,000 Americans will be infected this year, with 9,500 dying from the disease. In past generations, oral cancer was mostly linked to smoking, alcohol use or a combination of the two. But even as smoking rates have fallen, oral cancer rates have remained about the same, and researchers have documented in recent studies that this may be caused by HPV. HPV infects cells of the skin and the membranes that lines areas such as the mouth, throat, tongue, tonsils, rectum and sexual organs. Transmission can occur when these areas come into contact with the virus. HPV is a leading cause of cervical, vaginal and penile cancers. Surveys have shown that younger men are more likely to [...]

Oral Cancer Foundation News Team - A2016-10-26T08:15:03-07:00October, 2016|Oral Cancer News|

Pre-Teens need just two doses of HPV vaccine, not three: Feds

Source: www.nbcnews.com/health Author: Maggie Fox There's good news for kids who haven't received all their HPV vaccines yet - they only need two doses of the vaccine instead of three, federal government advisers said Wednesday. The new recommendations should make it easier to get more children vaccinated against the human papillomavirus (HPV), which causes a range of cancers including cervical cancer, throat cancer and mouth cancer, officials said. "It's not often you get a recommendation simplifying vaccine schedules," said Dr. Nancy Messonnier, Director of the National Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention. The CDC immediately accepted the recommendations from its Advisory Committee on Immunization Practices. "Safe, effective, and long-lasting protection against HPV cancers with two visits instead of three means more Americans will be protected from cancer," said CDC Director Dr. Tom Frieden. "This recommendation will make it simpler for parents to get their children protected in time." The CDC says every pre-teen boy and girl should get the vaccine, but fewer than a third have received all three doses. Messonnier says the three-dose schedule was based on the earliest studies of the vaccine. New studies show that two doses protect people for decades from the cancer-causing virus. And studies also suggest that spacing the two doses a year apart is at least as effective, if not more effective than giving them more closely together - something that could also make it easier to get kids fully vaccinated. Older teens who have [...]

Oral Cancer Foundation News Team - A2016-10-20T11:10:26-07:00October, 2016|Oral Cancer News|

Mouth, throat cancers caused by HPV on the rise, especially among Canadian men

Source: www.ctvnews.ca Author: Sonja Puzic, CTVNews.ca Staff Mouth and throat cancers caused by the human papilloma virus have been rising steadily over the past two decades, with a “dramatic” increase among Canadian men, according to a new report from the Canadian Cancer Society. The special report on HPV-associated cancers, released Wednesday as part of the 2016 Canadian Cancer Statistics breakdown, says the rate of mouth and throat cancers in men is poised to surpass the rate of cervical cancer diagnoses in women. Researchers and doctors have known for decades that certain strains of HPV – the most commonly sexually transmitted disease in Canada and the world -- cause cervical cancer. But the latest Canadian cancer statistics show that only 35 per cent of HPV cancers are cervical, and that about 33 per cent of HPV cancers occur in males. The latest data show that about one-third of all HPV cancers in Canada are found in the mouth and throat. Between 1992 and 2012, the incidence of HPV-related mouth and throat cancers increased 56 per cent in males and 17 per cent in females. In 1992, the age-standardized incidence rate (or ASIR) of those cancers was 4.1 per 100,000 Canadian males. In 2012, it was 6.4 per 100,000 males. In females, the rate was 1.2 in 1992 and 1.4 in 2012. ‘I thought I was done’ Three years ago, Dan Antoniuk noticed a lump on his neck and initially thought that it was just a swollen gland. But when the Edmonton [...]

Oral Cancer Foundation News Team - A2016-10-19T09:25:21-07:00October, 2016|Oral Cancer News|

Merck KGaA, Pfizer and Transgene team up on cancer vaccine

Source: www.biopharmadive.com Author: Joe Cantlupe Dive Brief: Transgene announced Tuesday it is teaming up with Merck KGaA of Darmstadt, Germany, and Pfizer to evaluate the possibilities of the combination of its human papillomavirus (HPV)-positive head and neck cancer vaccine TG40001 with big pharma’s avalumab in a Phase 1/2 study. The incidence of HPV-related head and neck cancers has increased significantly, with one variation, HPV-16 accounting for 90% of all HPV-related head and neck cancers. HPV-16 is a subset of head and neck squamous cell carcinoma (HNSCC), a group of cancers that can affect the mouth and throat. Global spending on head and neck cancer indications amounted to $1 billion in 2010, according to the companies’ recent estimates. Current treatments for the disease include surgical resection with radiotherapy or chemo-radiotherapy; the companies say they are exploring better options for advanced and metastatic HPV and HNSCC. Dive Insight: The current deal between the big pharma partners and Transgene highlights the industry's efforts to create combination therapies to treat cancer. Virtually every company in the space has embraced the idea that using multiple modes of attack could be the only way to eventually find cures for the many forms of cancer; companies have been teaming up in hopes of finding that crucial pairing. In previous clinical trials, TG4001 has demonstrated promising activity in terms of HPV viral clearance and was well tolerated, according to Transgene. TG4001 is one of the few drugs targeting HPV-associated cancers that can be combined with an immune checkpoint [...]

Oral Cancer Foundation News Team - A2016-10-13T07:41:07-07:00October, 2016|Oral Cancer News|