Sanofi Pasteur MSD’s HPV vaccine Gardasil(R) wins Prix Galien award

Source: www.medicalnewstoday.com Author: staff The two HPV vaccines currently licensed for use in the UK were jointly awarded the coveted Prix Galien Medal for Innovation at a ceremony held on Wednesday evening in the Palace of Westminster, House of Commons. "We are absolutely delighted at the recognition given to the world's leading HPV vaccine Gardasil® - this award reflects the work of many people, all around the world, involved in making the dream of a cancer vaccine a reality", said Dr Nicholas Kitchin, Medical Director, accepting the award on behalf of the Sanofi Pasteur MSD team. "Both companies have developed the technology of HPV vaccines down different paths," he continued, "we chose a quadrivalent vaccine strategy, targeting a broader range of HPV-related genital disease than cervical cancer alone, with the aim of delivering additional benefits for patients and healthcare systems." The joint award for the two HPV vaccines, developed by Sanofi Pasteur MSD and GSK, was presented by Andrew Lansley CBE MP, Shadow Secretary of State for Health. The distinguished panel of seven judges, chaired by Professor Sir Michael Rawlins, selected the HPV vaccines as the winners from seven innovative products that reached the final. Vaccines have won in four of the last five Prix Galien awards and the UK award for Gardasil® follows similar success in Prix Galien competitions in the USA and France. Current experience with the four-type HPV vaccine Thirty years after the discovery that human papillomavirus (HPV) can cause cervical cancer, 15 years after the start [...]

2008-09-29T18:53:38-07:00September, 2008|Oral Cancer News|

HPV increases men’s risk for oral cancer, prompts calls for vaccine: pathology expert Dr. Shashi Pawar on HPV health concerns for men

Source: www.prweb.com Author: press release HPV, the human papillomavirus, is well known for its role in causing cervical cancer in women - so much so, in fact, that the National Institutes of Health recommend all girls be vaccinated against the virus when they are 11 or 12, prior to becoming sexually active. However, recent research shows that women are not the only ones at risk for developing HPV-related cancers. Oral cancers caused by the virus are increasing rapidly in men, and researchers suggest HPV may soon overtake tobacco use as the leading cause of these cancers of the mouth, tongue, throat and tonsils. "The human papillomavirus is one of the most insidious and dangerous sexually transmitted diseases for women, as it has been linked to a vast majority of cervical cancers," explains Dr. Shashi Pawar, PhD, FACMG, Director of Genetics at Acupath Laboratories. "We are now seeing the effects of HPV infection in men, and the marked increase in oral cancer - coupled with the well-known increased risk for penile and anal cancers - suggests that both sexes face equally serious health consequences from this virus," Dr. Pawar notes. Cumulative research spurs call for men's vaccine A benchmark study that tracked more than 30 years of oral cancer data from the National Cancer Institute found that the rate of oral cancer caused by the HPV virus, rather than lifestyle habits such as smoking or chewing tobacco, has risen steadily since 1973 and is now about even with the incidence rate [...]

2008-09-28T21:27:18-07:00September, 2008|Oral Cancer News|

Winnipeg schools pick religion over HPV vaccine

Source: www.canada.com/vancouversun Author: Jen Skerritt, Winnipeg Free Press At least four Winnipeg private schools have opted not to vaccinate Grade 6 girls against a sexually transmitted infection linked to cervical cancer for "religious reasons." The decision comes weeks before Manitoba Health officials roll out the controversial Gardasil vaccine in schools across the province. Dr. Carol Kurbis, medical officer of health for the Winnipeg region, confirmed public health nurses will not attend at least four city private schools to vaccinate 11 and 12-year-old girls against human papillomavirus (HPV) next month. "We don't have any ability to force them into the program and those schools have actually been co-operative in still distributing information out to parents," Kurbis said. "There's four or five, and they're relatively small schools." The province's $10.8-million HPV vaccine program is set to launch in Winnipeg schools the first week of October. Researchers still have no idea when the immunity against HPV wears off and some critics believe mass promotion could lead some women to believe they're protected against other sexually transmitted infections, like the potentially deadly HIV. Some parent groups worry the vaccine sends the wrong message and may encourage preteen girls to engage in sexual activity. Robert Praznik, director of education for the Archdiocese of Winnipeg, said he can't understand why certain schools would opt out of the vaccination program. Praznik said the Archdiocese has directed the 14 local Catholic elementary schools to leave the question of whether to vaccinate preteen girls against HPV up to parents. [...]

2008-09-20T08:24:06-07:00September, 2008|Oral Cancer News|

Vaccine controversy continues

Source: Reader's Digest (www.rd.com) Author: Julie Bain Between the relay races and table tennis triumphs last week, there was some news coverage about the HPV vaccine. A study came out last Wednesday in the New England Journal of Medicine that looked at the economic impact of vaccinating young girls and women from the types of HPV virus that can cause cervical cancer. Newsweek ran an informative Q and A with one of the study authors about who should get the vaccine and when. The New York Times did a big story, too, which I thought displayed a bit of bias in the disapproving tone of its headline: Researchers Question Wide Use of HPV Vaccines. I called Maura Gillison, MD, a researcher at Johns Hopkins in Baltimore and one of the top experts on HPV, for her perspective. She said, “For those of us in the field, this study is not really new information. It is known that the HPV vaccine doesn’t have an impact on young women who have already been infected by the HPV types targeted by the vaccine (HPV6, 11, 16, and 18).” While it was possible to measure a girl’s previous exposure to HPV in the study lab, it’s not possible in a medical clinic, she says. That’s why it’s not as cost-effective to give the vaccine to women who are already sexually active. Still, she says, “only 4% of the 16- to 26-year-old women who were enrolled in the vaccine trials had evidence of exposure to [...]

Louisville Researchers Make Breakthrough With HPV

Source: WLKY.com Author: staff Looking at Petri dishes and transferring chemical solutions may not look exciting, but if you understood what doctors Alfred Jenson and Shin-Je Ghim have discovered in doing just that, it could save your life. Now, the same scientists have made another discovery concerning the virus, and it could potentially save nearly 50,000 lives a year. "The reason it's so exciting is because we developed the vaccine for the cervical cancer because 100 percent of cervical cancer is caused by the human papillomavirus," said Jenson. "Now it looks like during the last year, up to 50 percent of head and neck cancers are caused by the human papillomavirus." So having a vaccine that's 100 percent effective against the human papillomavirus means the same vaccine is going to be able to prevent both cervical cancer and head and neck cancer. HPV is known to be transferred by sexual intercourse and through the birth canal. So how did it manifest in the head and neck? Doctors linked it to oral transmission. "There has been a change in the cause of head and neck cancers since 1972, and it's just been realized in the last couple of years," said Jenson. Cancer specialists realized there was a sharp rise, particularly in cancer of the tongue and tonsils. U of L's research team at the cancer center, led by resident Payal Desai, looked at the last seven years of patients who had cancerous tissue in those areas. Twenty-eight percent of the samples [...]

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