Court: Tobacco Health Labels Constitutional

Source: Reuters.com Combination picture of new graphic cigarette packages, released by the U.S. Food and Drug Administration June 21, 2011, shows a varied collection of a man on a ventilator, diseased lungs and dead bodies were among the graphic images for revamped U.S. tobacco labels, unveiled by health officials who hope the warnings will help smokers quit. Credit: Reuters/U.S. Food and Drug Administration/Handout By Terry Baynes (Reuters) - A U.S. law requiring large graphic health warnings on cigarette packaging and advertising does not violate the free speech rights of tobacco companies, a federal appeals court ruled on Monday. Cigarette makers had sued to stop the U.S. Food and Drug Administration's new labeling and advertising requirements on grounds the rules violated their First Amendment right to communicate with adult tobacco consumers. But the Cincinnati-based U.S. Court of Appeals for the 6th Circuit upheld the bulk of the FDA's new regulatory framework, including the requirement that tobacco companies include large warning images on cigarette packs. The decision comes on the heels of a Washington, D.C., judge's ruling in a different, but related, case that rejected the FDA requirements and seems to set up a clash over the constitutionality of the FDA rules. Floyd Abrams, a lawyer for Lorillard, noted the difference in tone in the two rulings and said the 6th Circuit case, the Washington case, or both, would likely end up in the U.S. Supreme Court. The difference in the two cases is that the FDA had not introduced the specific [...]

2012-03-21T10:43:06-07:00March, 2012|Oral Cancer News|

Nearly 800,000 Deaths Prevented Due to Declines in Smoking

Source: National Cancer Institute Twentieth-century tobacco control programs and policies were responsible for preventing more than 795,000 lung cancer deaths in the United States from 1975 through 2000, according to an analysis funded by the National Cancer Institute (NCI), part of the National Institutes of Health. If all cigarette smoking in this country had ceased following the release of the first Surgeon General’s report on smoking and health in 1964, a total of 2.5 million people would have been spared from death due to lung cancer in the 36 years following that report, according to the analysis.  The results of this study were published online March 14, 2012, in the Journal of the National Cancer Institute. “These findings provide a compelling illustration of the devastating impact of tobacco use in our nation and the enormous benefits of reducing rates of smoking,” said Robert Croyle, Ph.D., director of the Division of Cancer Control and Population Sciences at NCI.  “Although great strides have been made, we cannot relax our efforts.  The prevention and cessation of tobacco use continue to be vital priorities for the medical, scientific, and public health communities.” The researchers, part of the NCI-sponsored Cancer Intervention and Surveillance Modeling Network (CISNET), utilized a comparative modeling approach in which they constructed detailed cigarette smoking histories for individuals born from 1890 through 1970, and then related the histories to lung cancer mortality in mathematical models.  Using these models, the researchers were able to estimate the impact of changes in smoking patterns resulting [...]

2012-03-19T09:45:14-07:00March, 2012|Oral Cancer News|

Studies underscore genetic complexity of head and neck squamous cell cancers

Source: Dentistry IQ By Maria Perno Goldie, RDH, MS While we should be screening patients for oral and pharyngeal cancer daily, April has been designated as the month when we highlight this disease, and increase awareness about its prevention and treatment. Powerful new technologies that pinpoint the connections between human genes and diseases have clarified the background of cancer, singling out changes in tumor DNA that force the development of certain types of malignancies. Several major biomedical centers have collaborated to study head and neck squamous cell cancer. Their large-scale analysis has revealed a surprising new set of mutations involved in this disease. The studies underscored the genetic complexity of head and neck squamous cell cancers. Two independent, multi-institution research teams identified a large number of genetic defects associated with head and neck squamous cell carcinoma (HNSCC), the most common form of head and neck cancer. The researchers sequenced the entire protein-coding regions, or exomes, of the DNA in dozens of patient tissue samples.(1,2) Tobacco use, excessive alcohol consumption, and human papillomavirus (HPV) infection are known risk factors for HNSCC, including cancers occuring in the mouth and throat. The 5-year survival rate for many types of HNSCC has improved little over the past 40 years. According to the authors, the degree of differentiation, or tumor cell grade, has never consistently been shown to be a clinical prognostic factor in HNSCC. They said it was surprising to find mutations in a series of genes that appear to contribute to differentiation. Both [...]

2012-03-15T12:57:26-07:00March, 2012|OCF In The News, Oral Cancer News|

Cancer patients who smoke report worse pain, symptoms

Source: www.medscape.com/ Author: Kate Johnson Cancer patients who smoke experience more severe symptoms than nonsmoking cancer patients and are also at greater risk of misusing opioids, a new study shows. "Our findings show a profile of higher levels of physical symptoms (pain, fatigue, poor appetite, and insomnia) and psychological symptoms (depression and anxiety) among smokers than non-smokers," report Diane Novy, PhD, from the Pain Management Center at the University of Texas MD Anderson Cancer Center in Houston, Texas, and colleagues. The findings underscore the importance of smoking cessation for this patient population, she told Medscape Medical News, even though it's unclear if there is a causal effect. "We don't know the cause. They may smoke more because of the pain," she said in an interview. However, studies also show that smoking has been known to increase certain types of pain such as back pain, and nerve pain, she added. "If we can motivate them to stop smoking, I think they're better off." The findings were presented here at the American Academy of Pain Medicine (AAPM) 28th Annual Meeting. Pain, Fatigue, Insomnia The study included 486 cancer patients (52% female), with a mean age of 55 years, who were referred to the Pain Management Center for uncontrolled pain. Ninety-four patients were smokers, and the rest (n = 356), classified as nonsmokers, were former smokers or never-smokers. The patients were diagnosed with a wide range of cancers, the most common being gastrointestinal (18.5%), followed by hematologic (15%) and head and neck cancer [...]

2012-02-26T09:23:53-07:00February, 2012|Oral Cancer News|

UPDATE 1-Swedish Match pushes ahead with snus in the U.S

Source: Reuters.com STOCKHOLM, Feb 22 (Reuters) - Tobacco products group Swedish Match will step up promotion of moist Swedish-style snuff, called snus, in the United States this year where it expect the market to grow faster than its Scandinavian home territory. Snus, a tobacco product put under the lip and sucked, mostly in pouches, is the group's main cash cow, sold mainly in Scandinavia. Swedish Match wants to differentiate itself in the larger U.S. market by growing sales of snus, which is pasteurized and has a different texture and taste to fermented U.S.-style snuff. "During 2012, we will continue to invest for growth. In the U.S. we will expand distribution and invest further in marketing activities ...," said Swedish Match, which is the largest producer of snus in Sweden. The product is banned in the rest of the European Union. Swedish Match, a rival to Altria Group Inc, Reynolds American Inc and BAT., also makes cigars. Marketing costs for snus in the U.S. weighed on fourth-quarter profit, the group said on Wednesday. Operating profit fell to 1.02 billion crowns ($153.6 million) from a year-earlier 1.42 billion, against a mean forecast for 1.03 billion in a Reuters poll of analysts. It said significantly higher international snus investments weighed on the profit margin for snuff and snus, which make up more than half of profit. The margin fell to 45.9 percent from 48.1 percent, well below a forecast for 47.6 percent. As well as aiming at the U.S. market, its venture with [...]

2012-02-24T10:27:50-07:00February, 2012|Oral Cancer News|

Head and neck cancer in transplant patients: For better or worse?

Source: medicalxpress.com Author: Henry Ford Health System staff Transplant patients who develop head and neck cancer are more likely to be non-smokers and non-drinkers, and less likely than their non-transplant counterparts to survive past one year of diagnosis, according to a new study from Henry Ford Hospital in Detroit. As part of a 20-year review, Henry Ford researchers found cancers of the throat, tonsils and mouth may be more aggressive in transplant recipients as the result of long-term immunosuppressive therapy required to prevent solid organ rejection. Transplant patients in the study who developed skin cancer in the head and neck region were more likely to have multiple lesions, compared to the general public. In all, 2.6% of transplant patients in the study developed some form of head and neck cancer. While the risk for developing head and neck cancer is small, the study serves as an important reminder to all transplant recipients to be vigilant about any changes to their skin, as well as persistent sore throat, ear pain or swallowing issues – all signs of head and neck cancer. "The benefits of organ transplantation and immunosuppressive therapy still outweigh the risk of transplant patients developing head and neck cancer," says study author Robert Deeb, M.D., with the Department of Otolaryngology-Head & Neck Surgery at Henry Ford. "Still, our study highlights that head and neck cancer arising in transplant patients warrants the need for regular screenings and aggressive treatment." The study will be presented Jan. 28 in Miami Beach at [...]

Prevalence of Oral HPV Infection Higher Among Men Than Women

CHICAGO -- The overall prevalence of oral human papillomavirus (HPV) infection is approximately 7 percent among men and women ages 14 to 69 years in the United States, while the prevalence among men is higher than among women, according to a study appearing in JAMA. The study is being released early online to coincide with its presentation at the Multidisciplinary Head and Neck Cancer Symposium. Oral HPV infection is the cause of a subset of oropharyngeal [relating to the mouth and pharynx] squamous cell carcinomas (OSCC).  Human papillomavirus positive OSCC are associated with sexual behavior in contrast to HPV-negative OSCC that are associated with chronic tobacco and alcohol use. At least 90 percent of HPV-positive OSCC are caused by high-risk (or oncogenic) HPV type 16 (HPV-16), and oral infection confers an approximate 50-fold increase in risk for HPV-positive OSCC. The incidence of OSCC has significantly increased over the last 3 decades in several countries, and HPV has been directly implicated as the underlying cause, according to background information in the article. Although oral HPV infection is the cause of a cancer that is increasing in incidence in the United States, little is known regarding the epidemiology of infection. Maura L. Gillison, M.D., Ph.D., of the Ohio State University Comprehensive Cancer Center, Columbus, and colleagues examined the  prevalence of oral HPV infection in the United States. The researchers used data from a cross-sectional study as part of the National Health and Nutrition Examination Survey (NHANES) 2009-2010, a statistically representative sample of the U.S. population. Men and women ages 14 [...]

2012-01-26T17:50:44-07:00January, 2012|Oral Cancer News|

Which Cancers Are Increasing Among Older Adults?

Source: AARP Cancers of the mouth and throat related to oral sex, as well as thyroid, liver and skin cancers are on the rise among older adults, according to  new stats released last week from the American Cancer Society. There was some good news, however. The death rate is down for the well-known major cancers. The society’s Cancer Statistics 2012 report found that overall, cancer deaths dropped by nearly two percent for both men and women  from 2004 to 2008. That may sound paltry, but Len Lichtenfeld, M.D., the society’s deputy chief medical officer, says it is more significant than it seems: Many people avoided even hearing the words “you have cancer” because advances in cancer treatment caught problems early, while still in the pre-cancerous stage, he said. The report found that death rates were down for all four major cancers — lung, colorectal, breast and prostate. The biggest drop was for lung cancer, which is down almost 40 percent in the number of men dying from the disease, thanks to fewer Americans smoking. Deaths among women from breast cancer declined 34 percent, mainly because of increases in mammogram screening and a decrease in hormone use for menopause, the ACS report said. On the other hand, some cancers are increasing, particularly among older Americans. According to Medscape News , the ACS found that people 55 to 64 years of age had the highest increase in incidence rates for liver and HPV-related oral cancers; people 65 and older also had an increase in incidence rates [...]

2012-01-10T14:48:32-07:00January, 2012|Oral Cancer News|

Boys need the cervical cancer jab, too

Source: www.telegraph.co.uk Author: Max Pemberton Few politicians will ever admit they are wrong, so I salute health ministers who have finally capitulated to medical opinion and last month announced a U-turn on the cervical cancer vaccine that is given to 12- and 13-year-old girls. Until now, Cervarix, which protects against two strains of the human papilloma virus (HPV) that are a factor in at least 70 per cent of diagnoses, has been the NHS vaccine of choice. However, another vaccine, Gardasil, also protects against a further two strains of HPV which cause genital warts, the most common sexually-transmitted infection, requiring costly and unpleasant treatment. As doctors have been arguing for some time, this has important public health implications. The current cost to the NHS of treating the 100,000 new cases of genital warts in England each year is £23 million. In several countries, including Australia, where Gardasil has been used in nationwide vaccination programmes, a 75 per cent decrease in the number of new cases of genital warts in the past three years has been reported. Critics of NHS policy complained that Cervarix was chosen over Gardasil not on the basis of clinical efficacy but because its manufacturers offered it at a discounted price, making it the most cost-effective. Indeed, many doctors have admitted in the medical press that they have bought Gardasil for their daughters privately, while they had to give their patients Cervarix. But ministers have seen sense as now Gardasil will be available on the NHS. But the [...]

2011-12-05T09:29:57-07:00December, 2011|Oral Cancer News|
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