smoking – Page 11 – Oral Cancer News

Even moderate drinking may substantially raise risk of dying from cancer

Source: www.nydailynews.com Author: Tracy Miller, New York Daily News Alcohol causes about 19,500 cancer deaths each year — and even as little as 1.5 drinks per day can make you part of that statistic, according to a sobering new study. The research, published in the American Journal of Public Health, is the first in several decades to examine deaths from a variety of cancers that can be attributed to alcohol consumption, said lead study author David E. Nelson of the National Cancer Institute. "One of the reasons we did the study was to update data that hadn't been looked at for 30 years," Nelson told the Daily News. "In that time, other diseases, and other cancers, have been linked to alcohol." The researchers looked at mortality data from two national surveys conducted in 2009, and using a mathematical formula, determined which of the cancer deaths were alcohol related. About 3.2 to 3.7% of all cancer deaths in 2009 were attributed to alcohol, with oral cancers, pharynx, larynx and esophageal cancers the top killers in men, and breast cancer the most deadly in women. About 15% of all breast cancer deaths were attributable to alcohol consumption, the study found. Furthermore, while the risk of death was greatest among people who had three or more drinks per day, about 30% of deaths occurred among people who consumed 20 ounces, the equivalent of 1.5 drinks, per day. "There's no question that people who drink more frequently are at greater risk," Nelson said. "What [...]

Oral Cancer Foundation News Team - A2013-02-20T07:48:50-07:00February, 2013|Oral Cancer News|

Team approach improves oral cancer outcomes

Source: www.drbicuspid.com Author: Donna Domino, Features Editor Providence Cancer Center in Portland, OR, is one of a growing number of facilities that is working to improve care for patients with oral cancer and head and neck cancers through a multidisciplinary program that brings together a spectrum of treatment providers. To illustrate the challenges many oral cancer patients face, R. Bryan Bell, MD, DDS, medical director of the Oral, Head and Neck Cancer Program at Providence, described the extreme effects the illness and its treatment had on one of his patients. The woman had undergone surgery, chemotherapy, and radiation for her oral cavity cancer. "This was a beautiful 32-year-old woman who had lost all her teeth and couldn't chew," Dr. Bell told DrBicuspid.com. "She had aged about 40 years during treatment, and she just looked awful. But she had no means of affording needed dental rehabilitation, which would have cost about $60,000. People need to see what happens when you don't restore these patients." Dr. Bell used the woman's case to convince officials at Providence Health, which oversees the medical center, of the need for a multidisciplinary approach for these patients. The new cancer treatment center, which opened last month, is a unique collaboration between dental and medical oncology specialists. The center provides coordinated care for oral cancer patients who often need expensive and complex dental rehabilitation, regardless of their ability to pay, according to Dr. Bell. His team includes head and neck surgical oncologists, radiation oncologists, medical oncologists, otolaryngologists, neuro-otologists, [...]

Oral Cancer Foundation News Team - A2013-01-28T14:52:16-07:00January, 2013|Oral Cancer News|

Quitting smoking before cancer surgery best, study finds

Source: health.usnews.com Author: staff Cancer patients who smoked up until their surgery were more likely to take up the habit again compared to those who quit earlier, a new study finds. The study from the Moffitt Cancer Center in Tampa, Fla., included lung cancer and head and neck cancer patients who quit smoking before or immediately after surgery. They were followed for a year after the surgery. "Sixty percent of patients who smoked during the week prior to surgery resumed smoking afterward, contrasted with a 13 percent relapse rate for those who had quit smoking prior to surgery," study corresponding author Vani Nath Simmons said in a Moffitt news release. The significantly lower smoking relapse rate for those who quit smoking before surgery shows the need to encourage patients to quit smoking when they're diagnosed with cancer, the researchers said. The investigators also noted that most of the patients who began smoking again did so shortly after surgery, which shows the importance of anti-smoking programs for patients both before and after surgery. The study also found that patients were more likely to resume smoking if they had a high amount of fear about cancer recurrence, had a higher risk for depression, and were less likely to believe in their ability to quit smoking. "Cancer patients need to know that it's never too late to quit," Simmons said. "Of course, it would be best if they quit smoking before getting cancer; but barring that, they should quit as soon as they [...]

Oral Cancer Foundation News Team - A2013-01-28T14:43:06-07:00January, 2013|Oral Cancer News|

Experts warn of epidemic of head and neck tumors caused by sexually-transmitted HPV infections and obesity

Source: www.dailymail.co.uk Author: staff While cancer rates continue to drop, two new increasingly common causes of cancer could lead to an epidemic of head and neck cancer, experts warn. Obesity and the human papillomavirus, or HPV, are the next wave of cancer threats, according to a report released Monday with data from the American Cancer Society, the Centers for Disease Control and Prevention, the National Cancer Institute, and the North American Association of Central Cancer Registries. Baby boomers already infected with HPV will likely develop cancers from the virus in coming years and the youger generation is not being vaccinated against it at anything close to the recommended rate. And a third of cancer cases have been linked to obesity, which is a growing health concern with little done to combat it. The report was published by the Journal of the National Cancer Institute. From 2000 to 2009 cancer death rates dropped steadily by 1.8 per cent among children and men and 1.4 per cent among women. Cancer diagnosis rates were stable for women, dipped slightly among men, and went up a tiny 0.6 per cent among children under 14. 'The fact that people are not dying of cancer is clear evidence of progress,' Dr. Otis Brawley of the American Cancer Society told MSNBC. 'But could have a much lower death rate from cancer if we simply got serious about doing all the things that work. 'Over the next 10 years, a combination of high caloric intake and low physical activity [...]

Oral Cancer Foundation News Team - A2013-01-10T09:52:16-07:00January, 2013|Oral Cancer News|

DNA adducts linked to oral cancer in smokers

Source: www.news-medical.net Author: Sarah Guy, medwireNews Reporter Having a high susceptibility to certain types of DNA damage caused by tobacco smoking could significantly increase the risk for oral cancer, show results of a Taiwanese study. Levels of BaP 7,8-diol 9,10-epoxide (BPDE) - a metabolite of Benzo[a]pyrene, an important carcinogen found in cigarette smoke - correlated positively with smoking status in a cohort of individuals with oral cancer, report the researchers. The findings also indicate a significantly increased risk for oral cancer among individuals with high DNA adduct levels compared with their peers with low levels. "Based on our finding, we suggest that detected BPDE-like DNA adducts could be used as a biomarker for oral cancer risk," write Huei Lee (Taipei Medical University) and colleagues in the Archives of Oral Biology. The team analyzed BPDE-DNA adduct levels in oral tissue samples from 158 oral cancer patients and 64 individuals without cancer (controls), using immunohistochemistry and enzyme-linked immunosorbent assay (ELISA). The results of these assays significantly and positively correlated , so that immunohistochemistry-negative patients did not have detectable DNA adduct levels using ELISA and vice versa. DNA adduct levels also positively correlated with smoking status among the cancer patients, note the researchers, with significantly higher adduct levels among smokers than nonsmokers, at 93.18 versus 0.04 adducts per 108 nucleotides. Lee and co-workers also observed that cancer patients had significantly higher DNA adduct levels than controls, at a range of 0-358.00 versus 0-39.50 adducts per 108 nucleotides. Indeed, DNA adduct level was an [...]

Oral Cancer Foundation News Team - A2013-01-05T15:32:56-07:00January, 2013|Oral Cancer News|

DNA adducts linked to oral cancer in smokers

Source: www.news-medical.net Author: Sarah Guy, medwireNews Reporter Having a high susceptibility to certain types of DNA damage caused by tobacco smoking could significantly increase the risk for oral cancer, show results of a Taiwanese study. Levels of BaP 7,8-diol 9,10-epoxide (BPDE) - a metabolite of Benzo[a]pyrene, an important carcinogen found in cigarette smoke - correlated positively with smoking status in a cohort of individuals with oral cancer, report the researchers. The findings also indicate a significantly increased risk for oral cancer among individuals with high DNA adduct levels compared with their peers with low levels. "Based on our finding, we suggest that detected BPDE-like DNA adducts could be used as a biomarker for oral cancer risk," write Huei Lee (Taipei Medical University) and colleagues in the Archives of Oral Biology. The team analyzed BPDE-DNA adduct levels in oral tissue samples from 158 oral cancer patients and 64 individuals without cancer (controls), using immunohistochemistry and enzyme-linked immunosorbent assay (ELISA). The results of these assays significantly and positively correlated , so that immunohistochemistry-negative patients did not have detectable DNA adduct levels using ELISA and vice versa. DNA adduct levels also positively correlated with smoking status among the cancer patients, note the researchers, with significantly higher adduct levels among smokers than nonsmokers, at 93.18 versus 0.04 adducts per 108 nucleotides. Lee and co-workers also observed that cancer patients had significantly higher DNA adduct levels than controls, at a range of 0-358.00 versus 0-39.50 adducts per 108 nucleotides. Indeed, DNA adduct level was an [...]

Oral Cancer Foundation News Team - A2012-12-31T12:33:45-07:00December, 2012|Oral Cancer News|

Smokers are 40 times more likely to develop cancers in head and neck

Source: www.heraldandnews.com Author: Andrew Creasey, Staff Reporter The level of concern you should have for contracting cancer of the head and neck can be gauged by the answer to one simple question: Do you smoke? If the answer is no, chances are your oral cavities and voice box, the places cancers most commonly occur, will be safe from the onerous growth that can cause death if not treated soon enough. If the answer is yes, then you are 40 times more likely to contract head or neck cancer if you have been smoking for 10 years, and you should probably be aware of what to look for, said Dr. Richard DeVore, an otolaryngologist in Klamath Falls. Signs of head and neck cancer include a sore or ulcer that doesn’t heal, unexplained bleeding of the throat and, most importantly, throat or tongue pain that persists beyond several weeks, DeVore said. Such pain could be caused by the cancer, which actually eats into the tissue and can cause significant pain when it starts munching on the local nerves. Swallowing difficulties, hoarseness and lumps in the head and neck that don’t respond to antibiotics should also be examined, DeVore said. At the onset of such symptoms, it is vital to share them with a physician, DeVore said. Caught early, the cure rate of many neck and head cancers is 100 percent and can be solved with a simple operation. “The cure rates are slowly improving to some degree, but it’s a bad disease,” [...]

Oral Cancer Foundation News Team - A2012-10-23T07:51:35-07:00October, 2012|Oral Cancer News|

Top EU official resigns after snus bribe probe

Source: www.thelocal.se A complaint by Swedish Match about a suspected bribe meant to influence European tobacco policy has resulted in the resignation of EU health commissioner John Dalli, the European Union's top health official. "Commissioner John Dalli has today announced his resignation as a member of the Commission, with immediate effect," the European Commission announced in a statement released on Tuesday. Dalli's resignation, the first for a member of the Commission since 1999, came following the release on Monday of report detailing the findings of an investigation carried out by the EU's anti-fraud office, OLAF, into a complaint filed by Swedish tobacco company Swedish Match in May 2012. The complaint alleged that a Maltese entrepreneur sought to leverage his connections with Dalli, also of Malta, in order to "gain financial advantages" from Swedish Match in exchange for attempting to influence "a possible future legislative proposal on tobacco products, in particular on the EU export ban on snus". Snus – also known as Swedish snuff – is a tobacco product invented in Sweden in the early 1800s which has gained in popularity in Sweden after smoking was banned in restaurants in 2005. The sale of snus is outlawed in the European Union, but due to exemptions, it is still manufactured and consumed primarily in Norway and Sweden. The European Commission's Directorate-General for Health and Consumers Protection recently unveiled a proposal that would ban all smoke-free tobacco products outside of Sweden. The Swedish government has for years been trying to sway the [...]

Oral Cancer Foundation News Team - A2012-10-23T07:45:13-07:00October, 2012|Oral Cancer News|

Periodontitis increases risk of oral leukoplakia

Source: www.drbicuspid.com Author: Donna Domino, Features Editor Periodontitis increases the risk of developing oral leukoplakia and mucosal lesions that are predisposed to become oral cancer, according to a study in Oral Oncology (September 2012, Vol. 48:9, pp. 859-863). The findings provide clues into the complex relationship between systemic and local disease, noted the study authors from the University of Greifswald in Germany. The development of oral cancer proceeds through discrete molecular changes that are acquired from loss of genomic integrity after continued exposure to environmental risk factors. It is preceded in the majority of cases by clinically evident, potentially malignant oral disorders, the most common of which is leukoplakia, the researchers noted. Leukoplakia is an asymptomatic lesion in the oral mucosa. Oral cancer -- especially oral squamous cell carcinoma -- often develops out of these lesions, they added. Studies have shown that as many as 18% of oral premalignant lesions will develop into oral cancer. In addition, periodontal sites are often involved in proliferative types of leukoplakia. The oral cancer rate attributed to leukoplakia is between six and 29 per 100,000, according to the authors. Smoking and drinking alcohol are the main risk factors for this disease, but acute infections in the oral cavity may contribute to the risk. Inflammatory markers The study evaluated 4,310 German residents ages 20 to79 from 1997 to 2001. After five years, 3,300 participants were available for follow-up. The periodontal assessment included probing depth, clinical attachment loss, plaque, bleeding on probing, and the number of [...]

Oral Cancer Foundation News Team - A2012-10-04T14:06:25-07:00October, 2012|Oral Cancer News|

New gene test detects early mouth cancer risk

Source: www.health.am Researchers from Queen Mary, University of London have developed a new gene test that can detect pre-cancerous cells in patients with benign-looking mouth lesions. The test could potentially allow at-risk patients to receive earlier treatment, significantly improving their chance of survival. The study, published online in the International Journal of Cancer, showed that the quantitative Malignancy Index Diagnostic System (qMIDS) test had a cancer detection rate of 91-94 per cent when used on more than 350 head and neck tissue specimens from 299 patients in the UK and Norway. Mouth cancer affects more than 6,200 people in the UK each year and more than half a million people worldwide, with global figures estimated to rise above one million a year by 2030*. The majority of cases are caused by either smoking or chewing tobacco and drinking alcohol. Mouth lesions are very common and only five to 30 per cent may turn into cancers. If detected in the early stages treatment can be curative, but until now no test has been able to accurately detect which lesions will become cancerous. The current diagnostic gold standard is histopathology – where biopsy tissue taken during an operation is examined under a microscope by a pathologist . This is a relatively invasive procedure and many mouth cancers are being diagnosed at later stages when the chances of survival are significantly reduced. For patients presenting with advanced disease, survival rates are poor (10-30 per cent at five years). Lead investigator and inventor of [...]

Oral Cancer Foundation News Team - A2012-10-04T13:58:21-07:00October, 2012|Oral Cancer News|