NCI-designated Cancer Centers Urge HPV Vaccination for the Prevention of Cancer

Source: www.medicine.wustl.eduAuthor: Washington University School of Medicine in St. Louis Staff Approximately 79 million people in the United States are currently infected with a human papillomavirus (HPV) according to the Centers for Disease Control and Prevention (CDC), and 14 million new infections occur each year. Several types of high-risk HPV are responsible for the vast majority of cervical, anal, oropharyngeal (middle throat) and other genital cancers. The CDC also reports that each year in the U.S., 27,000 men and women are diagnosed with an HPV-related cancer, which amounts to a new case every 20 minutes. Even though many of these HPV-related cancers are preventable with a safe and effective vaccine, HPV vaccination rates across the U.S. remain low. Together we, a group of the National Cancer Institute (NCI)- designated Cancer Centers, recognize these low rates of HPV vaccination as a serious public health threat. HPV vaccination represents a rare opportunity to prevent many cases of cancer that is tragically underused. As national leaders in cancer research and clinical care, we are compelled to jointly issue this call to action. According to a 2015 CDC report, only 40 percent of girls and 21 percent of boys in the U.S. are receiving the recommended three doses of the HPV vaccine. This falls far short of the goal of 80 percent by the end of this decade, set forth by the U.S. Department of Health and Human Service’s Healthy People 2020 mission. Furthermore, U.S. rates are significantly lower than those of countries such as [...]

2016-02-04T12:35:06-07:00February, 2016|Oral Cancer News|

Rodeo Insider: Cowboy takes it on himself to ride home a message

Source: www.star-telegram.comAuthor: Brett Hoffman  Bronc rider Cody Kiser is trying to encourage cowboys to abstain from tobacco. Richard W. Rodriguez Star-Telegram   In a day when rodeo riders are approaching the sport from an athletic standpoint more than ever, there’s a heavier emphasis on physical fitness and many competitors are taking a closer look at abstaining from substances such as alcohol and tobacco. One cowboy attempting to send a message about abstaining from frequent tobacco consumption is bareback bronc rider Cody Kiser. “A lot of these cowboys don’t smoke or chew, and if they do, it’s really rare,” Kiser said. “A lot of the guys consider themselves as athletes. So they want to keep their bodies at an optimum performance and they don’t want to do anything that would break them down.” When the Fort Worth Stock Show conducted the opening performance of its 16-day Professional Rodeo Cowboys Association show on Friday, Kiser turned in a bareback score of 80, the highest marking of the night. As he competed in the renowned rodeo, Kiser wore a patch on his shirt that said: “Oral Cancer Foundation.” The foundation’s website lists Kiser and a spokesman and states: “The western/rodeo environment has had a long-term relationship with tobacco, and until 2009 the PRCA had a lengthy history of tobacco sponsorship money. While that has ended, tobacco use, and smokeless/spit tobaccos still thrive in the sport. While adults have the right to make any lifestyle choice, they inadvertently expose impressionable young people to what [...]

2016-01-26T15:26:25-07:00January, 2016|OCF In The News, Oral Cancer News|

Expanded age indication cleared for Gardasil 9 in males

Source: www.FormularyJournal.ModernMedicine.comAuthor: Erin Bastick FDA approved an expanded age indication for Human Papillomavirus 9-valent Vaccine, Recombinant (Gardasil 9, Merck) in males. Seven HPV types in Gardasil 9 (HPV 16, 18, 31, 33, 45, 52, and 58) cause approximately 90% to 95% of HPV-related anal cancers, 90% of cervical cancers, and 80% of high-grade cervical lesions worldwide.These 7 types also cause the majority of HPV-related vulvar and vaginal cancers. Gardasil 9 includes the greatest number of HPV (Human Papillomavirus) types of any available HPV vaccine. Gardasil 9 was previously approved for use in girls and young women aged 9 to 26 years for the prevention of cervical, vulvar, vaginal, and anal cancers caused by HPV 16, 18, 31, 33, 45, 52, and 58, precancerous or dysplastic lesions caused by HPV 6, 11, 16, 18, 31, 22, 45, 52, and 58, and genital warts caused by HPV types 6 and 11. As for use in male patients, the vaccine was previously approved for use in boys aged 9 to 15 years for the prevention of anal cancer caused by HPV types 16, 18, 31, 33, 45, 52, and 58, precancerous or dysplastic lesions caused by HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58. With the newest approval, Gardasil 9 is now also indicated for use in males aged 16 to 26 years for the prevention of these diseases. According to the CDC, HPV vaccination rates are unacceptably low compared to rates for other adolescent vaccines, and vaccination coverage in [...]

2015-12-30T18:31:17-07:00December, 2015|Oral Cancer News|

Depressed Head and Neck Cancer Patients Have Lower Survival and Higher Recurrence Risk

Source: www.OncologyNurseAdvisor.comAuthor: Kathy Boltz, PhD Depression is a significant predictor of 5-year survival and recurrence in patients with head and neck cancer, according to a new study published in Pyschosomatic Medicine (doi: 10.1097/PSY.0000000000000256). These findings represent one of the largest studies to report on the impact of depression on cancer survival. Although depression can have obvious detrimental effects on a person's quality of life, its impact on cancer patients is more apparent, explained lead author Eileen Shinn, PhD, assistant professor of Behavioral Science at The University of Texas MD Anderson Cancer Center, in Houston. Increasing evidence shows modest associations between elevated symptoms of depression and greater risk for mortality among patients with lung, breast, ovarian, and kidney cancers. The research team sought to clarify the influence of depression on survival, focusing their analysis on a single cancer type. By limiting the sample set and adjusting for factors known to affect outcome, such as age, tumor size, and previous chemotherapy, they were able to uncover a more profound impact of depression. The researchers followed 130 patients at MD Anderson with newly diagnosed oropharyngeal squamous cell carcinoma (OSCC), a type of cancer in which the tumor originates at the back of the throat and base of the tongue. At the beginning of their radiation therapy, Patients completed a validated questionnaire at the beginning of their radiation therapy to identify symptoms of clinical depression. Researchers monitored the participants, all of whom completed treatment, until their last clinic visit or death, a median period of [...]

2015-12-30T18:15:58-07:00December, 2015|Oral Cancer News|

Poison’s Rikki Rockett Reveals He Is Battling Oral Cancer

Source: www.loudwire.comAuthor: Chad Childers Poison drummer Rikki Rockett revealed during an appearance on the Eddie Trunk Live radio show that he’s completed nine rounds of chemotherapy and seven weeks of radiation treatments after being diagnosed with oral cancer this past summer and that he’ll find out in February if the treatments were successful. Rockett told Trunk (as transcribed by Blabbermouth), “[In] June, I kind of got sick. I had this horrible cold, sore-throat thing, and they were scoping me and they were doing biopsies, and nothing was coming up. And finally a doctor at USC did a biopsy and took a look and he said, ‘I believe you have oral cancer.’ And what it was is a tumor at the base of my tongue … This is very similar to Bruce Dickinson, very similar to Michael Douglas, similar to Tom Hamilton, as far as I know; I don’t know the details of his. And two adjacent lymph nodes that it kind of … Normally, it does spread to the lymph nodes; that’s typical. That’s how you find out you have it ninety percent of the time.” According to the Rockett, his doctor told him that it was a very treatable cancer, but was “a son of a bitch to treat.” He was then told that he would either have to undergo radiation and chemotherapy at the same time or undergo surgery, but even if he chose the latter, he might still have to do radiation and chemotherapy. Rockett revealed that it [...]

2015-12-15T16:23:53-07:00December, 2015|Oral Cancer News|

Forward Science and Oral Cancer Foundation partner in video to spread oral cancer awareness

Source: www.DentistryIQ.comAuthor: DentistryIQ Editors Click here to view Carol Layer's story, told by her daughter Rachel In an effort to increase awareness about the importance of annual oral cancer screenings, Forward Science, the creators of OralID, and the Oral Cancer Foundation have partnered to share the story of a family’s loss after a protracted and difficult battle with oral cancer. In a video narrated by the daughter of an oral cancer victim, the importance of regular/routine oral cancer screenings is stressed, and the daughter shares a first-hand view of why early detection is critical. To view the touching story of Carol Layer’s fight with oral cancer, told by her extraordinary daughter, Rachel, visit http://www.oralid.com/carolsfight. “Until there is a cure, the best solution is early discovery. Early detection can not only save people’s lives, but preserve the quality of life.” Rachel continues to compete in marathons and relay races in her mother’s memory, wearing “Carol’s Fight” on her shirt in every race. She emphasizes the importance of sharing her mom’s story with the world, with the hope of preventing future stories like her own. She said, “I certainly learned a lot about life and death and what it meant to be resilient through her, and I hope my mom’s story carries forward to people.” At 44 years old, Carol Layer had no traditional risk factors (alcohol or tobacco use) and was not a patient who was in the high-risk category for oral cancer. Carol found a lesion on the side of her tongue [...]

2015-12-10T17:36:58-07:00December, 2015|OCF In The News, Oral Cancer News|

Head, Neck Cancer Patients May Be at Higher Risk for Suicide: Study

Source: www.health.usnews.comAuthor: Robert Preidt THURSDAY, Nov. 12, 2015 (HealthDay News) -- Head and neck cancer patients may be at raised risk for suicide, new research suggests. However, the overall risk is still small, the findings showed. The study included over 350,000 patients in the United States diagnosed with head and neck cancer between 1973 and 2011. Of those patients, 857 died by suicide. The investigators found that the suicide rate among head and neck cancer patients was three times higher than in the general population. And suicide rates were higher among patients treated with radiation alone compared to surgery alone. Suicide rates were highest among those with cancers of the lower part of the throat, including the larynx ("voice box") and hypopharynx, at five times and 12 times higher, respectively, than in the general population. "This may be linked to these anatomic sites' intimate relationship with the ability to speak and/or swallow. Loss of these functions can dramatically lower patients' quality of life," Dr. Richard Chan Woo Park, of Rutgers New Jersey Medical School, and colleagues wrote. "It is possible that the increased rates of tracheostomy [breathing tube] dependence and dysphagia [difficulty swallowing] and/or gastrostomy [feeding] tube dependence in these patients are . . . factors in the increased rate of suicide observed," the authors added. The study was published online Nov. 12 in the journal JAMA Otolaryngology--Head & Neck Surgery. "While there is a considerable body of research that examines survival outcomes for patients with head and neck cancer, additional [...]

2015-11-13T15:34:55-07:00November, 2015|Oral Cancer News|

FDA Clears First Tobacco Product for Marketing

For the first time since it was given the power to regulate tobacco, the US Food and Drug Administration (FDA) has authorized marketing of a new product. The agency said that eight new smokeless snus products, to be sold in the United States under the "General" brand name by Stockholm-based Swedish Match AB, are now authorized under the premarket tobacco application pathway, which was established by the 2009 Family Smoking Prevention and Tobacco Control Act. Snus cannot be marketed as "FDA-approved," however. "Today's action demonstrates that the premarket tobacco application process is a viable pathway under which products can be marketed, as long as the public health can be protected," said Mitch Zeller, director of the FDA's Center for Tobacco Products, in a statement. This is the first time any tobacco maker has completed the rigorous premarket tobacco application review process at the agency; others have had products approved by proving they are substantially equivalent to what is already on the market. The agency said that Swedish Match provided evidence that "these products would likely provide less toxic options if current adult smokeless tobacco users used them exclusively." The agency also agreed with the company that snus' availability would not result in substantial new use, delay quit attempts, or attract ex-smokers. Swedish Match had been seeking separately to remove warnings that snus is harmful, but the agency has not yet ruled on that request. In that separate application, Swedish Match was seeking to have the 10 types of snus it [...]

2015-11-13T15:25:42-07:00November, 2015|Oral Cancer News|

Why groundbreaking new cancer drugs still don’t work for most patients

Source: www.news.doximity.comAuthor: Brady Dennis Immunotherapy, which aims to harness the body's immune system to fight off certain cancers, has received plenty of attention, praise and investment in recent years. Breakthrough treatments for melanoma and other cancers have shown startling results, giving some patients months and often years of life they almost certainly would not otherwise have had. Yet, for all their promise, immune therapies have not produced such dramatic results for the majority of patients. The same drug that causes metastatic melanoma to vanish in one patient might have no effect on another. At best, only one or two patients out of five will respond to immunotherapy treatments -- remarkable numbers compared to past standards, but still far lower than anyone would like. New research published Monday in the journal Nature explores the molecular mechanisms that prevent immunotherapy drugs from working in some patients, and researchers hope the findings will help make the treatments more effective over time. In short, the researchers studied why certain tumors were able to evade immune therapies designed to unleash the body's defenses to fight cancer. They noted that tumors with a high concentration of "T cells," a type of white blood cell essential to the human immune system, were more responsive to the treatments. Tumors with a low number of T cells inside what researchers call the "cancer microenvironment" were far less responsive to the new drugs. "The tumors are acting to protect themselves," said Weiping Zou, a senior author of the study and a professor of surgery, immunology and biology at the University of Michigan's [...]

2015-10-30T12:28:18-07:00October, 2015|Oral Cancer News|

Researchers Find Hookah Smoking Can Lead to Serious Oral Conditions – Equivalent To Smoking 100 Cigarettes

Source: www.multivu.comAuthor: PR Newswire CHICAGO, Oct. 28, 2015 /PRNewswire/ -- According to the Centers for Disease Control and Prevention, 2.3 million Americans smoke tobacco from pipes, and many of those who smoke waterpipes, or hookahs, believe it's less harmful than cigarettes. However, research published in The Journal of the American Dental Association (JADA) suggests hookah smoking is associated with serious oral conditions including gum diseases and cancer. "We found that waterpipe smoking is associated with serious health problems affecting the head and neck region," said study author Teja Munshi, B.D.S., M.P.H of Rutgers University. "The public needs to know they are putting themselves at risk. They should be made aware of the dangers of smoking hookahs." The authors conducted a literature review that focused on waterpipe smoking and head and neck conditions. They found waterpipe smoking to be associated with gum diseases, dry socket, oral cancer and esophageal cancer among other conditions. According to the World Health Organization, smoking a hookah is the equivalent of smoking 100 cigarettes, based on the duration and number of puffs in a smoking session. "This study sheds light on the common misconception that smoking from a waterpipe is somehow safer than smoking a cigarette," said JADA Editor Michael Glick, D.M.D. "Whether you are smoking a cigarette, an e-cigarette, a cigar, or tobacco from a waterpipe, smoking is dangerous not only to your oral health but to your overall health." The American Cancer Society is hosting The Great American Smokeout on November 19, 2015, an annual event that encourages [...]

2015-10-29T12:32:23-07:00October, 2015|Oral Cancer News|
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