oral cancer – Page 31 – Oral Cancer News

Preoperative smoking cessation improves head and neck surgery outcomes

Source: Cancerpage.com Author: Staff NEW YORK (Reuters Health) - Even a short period of 4 to 8 weeks of smoking cessation prior to surgery to treat upper aerodigestive tract squamous cell carcinoma improves wound healing, according to a review of the literature. If the patient stays tobacco-free, the risk of cancer recurrence is substantially reduced. However, full cessation is required -- simply reducing the quantity of cigarettes smoked per day is of little benefit, Dr. Richard O. Wein from Tufts Medical Center, Boston, reports in the June Archives of Otolaryngology-Head and Neck Surgery. Studies of the impact of smoking cessation on surgical outcomes within the field of otolaryngology are few and contradictory, Dr. Wein points out. For his review, he drew on studies of smokers operated on for non-otolaryngology conditions as well as for head and neck tumors. The "bottom line," he says, is that "although conflicting reports exist within the literature concerning the impact of short-term smoking cessation, it should be noted that the sheer number of articles reporting the negative impact of continued tobacco use on postoperative pulmonary function and wound healing far outweighs those minimizing this impact." Furthermore, multiple studies indicate increased risk of recurrence or the development of a second cancer in patients who continue to smoke after their index cancers are diagnosed. One study, for example, found that 40% of patients who kept smoking after being treated definitively for a malignant oral cavity tumor had a recurrence or developed a second malignant lesion. Overall costs of care, the author [...]

Charlotte Parker2009-06-19T07:38:56-07:00June, 2009|Oral Cancer News|

Oral cancer survivor’s animal sanctuary being foreclosed

Source: The Press-Enterprise Author: JULISSA McKINNON After 21 years of sheltering crippled and slaughter-bound horses and other barnyard animals, Renee Duncan is losing her 12-acre rescue ranch to foreclosure. Now Duncan, a 63-year-old former emergency room nurse in remission from cancer, is scrambling to move dozens of rescued animals out of the gully in unincorporated Perris in southwest Riverside County long known as the Meadowbrook Animal Sanctuary and Haven. Until Duncan finds a permanent home, a neighbor is offering shelter to her and her 50-some horses, a couple of emus, two turkeys and dozens of goats, pigs and dogs. Though there are two people bidding on the ranch who say they would allow Duncan and her critters to stay as renters, Ocwen Bank, which is repossessing the ranch, has ordered Duncan to clear the property by 6 a.m. Monday. Eviction attorneys and brokers with Ocwen Bank declined to comment on the situation. Duncan said her nonprofit animal rescue is going under ironically because she always put her animals first. She said she began to run into financial trouble in 2005 after being diagnosed with throat and tongue cancer. She stopped working to undergo chemotherapy and radiation. Duncan refinanced the house three times to try to keep up with medical bills and animal care. As money grew tight, she always paid for animal feed and veterinary care, which amounts to about $3,000 a month, even if that meant not paying the mortgage. "I ended up with a $4,000-a-month payment at 12.5 [...]

Charlotte Parker2009-06-19T07:40:46-07:00June, 2009|Oral Cancer News|

Up in smoke: health insurers hold billions in tobacco stocks

Source: Southernstudies.org Author: Desiree Evans A recent study published in the New England Journal of Medicine found that major U.S., Canadian and British life and health insurance companies are investing billions of dollars in tobacco company stock. Researchers first revealed that health and life insurance companies had major investments in tobacco companies in 1995 in an article in the British medical journal Lancet. More than 10 years later, insurance companies are still deeply invested in "big" tobacco, despite the national calls upon them to divest. "Despite calls upon the insurance industry to get out of the tobacco business by physicians and others, insurers continue to put their profits above people's health," said Wesley Boyd, the new report's lead author and a faculty member of Harvard Medical School. "It's clear their top priority is making money, not safe-guarding people's well-being." The report found that seven health and life-insurance companies in both the United States and overseas have nearly $4.5 billion invested in companies whose affiliates produce cigarettes, cigars and chewing tobacco. "Although investing in tobacco while selling life or health insurance may seem self-defeating, insurance firms have figured out ways to profit from both," Boyd said. "Insurers exclude smokers from coverage or, more commonly, charge them higher premiums. Insurers profit -- and smokers lose -- twice over." The study highlights New Jersey-based Prudential Financial Inc., which sells life insurance and long-term disability coverage. With total tobacco holdings of $264.3 million, Prudential Financial is a major investor in three tobacco firms, including America's biggest cigarette [...]

Charlotte Parker2009-06-19T07:41:28-07:00June, 2009|Oral Cancer News|

Oral Cancer Survivor To Expose Dangers Of Chew Tobacco

Source: Middlesex-London Health Unit Author: Staff For Gruen Von Behrens, an encounter with chewing tobacco on a camping trip nearly two decades ago led to an addiction that not only changed his life, but the lives of hundreds of thousands of teens across North America who have heard his story. Today, the 31 year-old from Illinois tours the continent, using his life story as the backdrop for what can happen when teens get hooked on "Chew". Once a talented young baseball player with dreams of cracking a big league lineup, Von Behrens, has undergone more than 40 surgeries to rebuild his face and jaw, all necessary after he developed squamous cell carcinoma at 17, all consequences of his addiction to chewing tobacco. x-London Health Unit, its Youth Action Alliance, the One Life Crew, the Thames Valley District School Board and the London and District Catholic School Board are pleased to be hosting Von Behrens as he brings his "How Chew Tobacco Gave Me Cancer" presentation to London and Middlesex County next week. Von Gruen’s schedule will see him in London on Monday and Tuesday, then Strathroy on Wednesday and Thursday; a complete schedule of presentations follows this news release. While most of the presentations Gruen Von Behrens will make are specifically aimed at the student body at local high schools, the community will be able to hear his message on Thursday, June 11th at 7:00 p.m. at A. B. Lucas Secondary School in London. Sports teams are encouraged to attend this [...]

Charlotte Parker2009-06-08T09:56:52-07:00June, 2009|Oral Cancer News|

New broad-spectrum vaccine to prevent cervical cancer induces strong responses in animals

Source: Journal of the National Cancer Institute Author: Staff Wednesday, May 27, 2009 Mice and rabbits immunized with a multimeric-L2 protein vaccine had robust antibody responses and were protected from infection when exposed to human papillomavirus (HPV) type 16 four months after vaccination, according to a new study published in the May 26 online issue of the Journal of the National Cancer Institute. Current HPV L1-based vaccines are almost 100% protective against infection by the two HPV types that are responsible for 70% of all cervical cancer cases world wide. However, the existing vaccines provide limited protection against the other HPV types that cause cancer. With that limitation in mind, Richard Roden, Ph.D., of the Johns Hopkins University in Baltimore, and colleagues have been working on an alternate vaccine that is based on the HPV minor capsid protein L2, which is highly conserved between HPV types. Previous experiments showed that the L2 protein induced only a weak antibody response in animals. In the current study, Roden and colleagues linked together a short segment of the L2 protein from several HPV types to generate a single multimeric L2 fusion protein. They tested the ability of this multimeric-L2 protein to induce antibody responses in animals and its ability to protect them from subsequent infection with HPV type 16. Mice immunized with the multimeric L2 vaccine developed robust antibody responses against all of the HPV types tested, although the antibody titer was still lower than the type-restricted responses following vaccination with an existing [...]

Charlotte Parker2009-06-02T20:49:51-07:00June, 2009|Oral Cancer News|

Jeg Coughlin Sr. Chair filled by OSU’s Gillison

Source: Go2geiger.com Author: News Staff Leading human papilloma virus (HPV) expert Maura Gillison, MD, PhD, was officially named to the Jeg Coughlin Sr. Chair in Cancer Research during a special ceremony Wednesday night at the Longaberger Alumni House at The Ohio State University. "This is a dream come true for all of us," said Coughlin, who was surrounded by his four sons and many members of the extended Coughlin family. "This Chair represents a legacy that will continue forever. Cancer research takes commitment from a financial aspect and more importantly from a research and development side. Dr. Gillison has accomplished so many things already and we truly feel the best is yet to come." Gillison recently joined OSU's staff after a successful stint as associate professor at Johns Hopkins University School of Medicine in Baltimore, Md., where she was a member of the Sidney Kimmel Comprehensive Cancer Center. She now serves as professor of medicine in the division of hematology and oncology at OSU and is a member of the Cancer Control and Viral Oncology Programs at the Comprehensive Cancer Center. "Unfortunately, like so many other families, the Coughlins have been touched by cancer," Gillison said. "Now, they are a family on a mission. They put the same enthusiasm they bring to racing into cancer research. The Coughlin family has made it possible for me to take my research into a much broader direction and to really think outside of the box." Focusing on the role that [...]

Charlotte Parker2009-05-29T09:37:54-07:00May, 2009|Oral Cancer News|

R. J. Reynolds introducing ‘dissolvable’ tobacco

Source: KSPR News Author: News Staff Tobacco companies are facing new criticism, accused of targeting your kids. Not with ads, but with new types of tobacco products. Like Camel Snus, tea-bags filled with mint-flavored tobacco. R.J. Reynolds says Snus have become so popular, they're taking the next step -- totally dissolvable tobacco The company says it will solve all kinds of problems for traditional smokers. "They don't have second hand smoke. They don't have a litter problem. The product actually dissolves in your mouth as opposed to having to spit or extract something like a patch from your mouth like other smokeless products," says Tommy Payne of R. J. Reynolds. The company will soon test three new products: Camel Sticks that dissolve when you suck them, Minty Tobacco Strips that look like breath strips, and Orbs, flavored dissolvable tablets that some say look and taste like candy. Critics say R. J. Reynolds is doing what it did with Joe Camel -- marketing not to adult smokers, but smoker wanna-bes. "Really what you're doing with kids actually, it's kind of like a gateway drug. You're getting them addicted to nicotine, which then leads them to possibly wanting to do other things," says Dan Smith of the American Cancer Society. The Indiana Poison Control Center says just one Camel dissolvable delivers up to 300 percent of the nicotine found in just one cigarette. Take too many, and nicotine poisoning might set in, and you could develop oral cancer. R. J. Reynolds says [...]

Charlotte Parker2009-06-02T20:51:19-07:00May, 2009|Oral Cancer News|

Chewing tobacco use surges among boys

Source: Msnbc.msn.com Author: Staff WASHINGTON - Use of snuff and chewing tobacco by U.S. adolescent boys, particularly in rural areas, has surged this decade, a federal agency said in a report on Thursday that raised concern among tobacco control advocates. The use of such smokeless tobacco products increases the risk of oral cancer as well as heart disease and stroke. It leads to nicotine addiction just like cigarette smoking. The report by the U.S. Substance Abuse and Mental Health Services Administration showed a 30 percent increase in the rate of smokeless tobacco use among boys aged 12 to 17 from 2002 to 2007. Use by adults remained stable. In 2007, the report estimated that 566,000 boys in that age group had used chewing tobacco or snuff. "This trend toward more smokeless tobacco use by kids is of great concern," Danny McGoldrick, vice president for research at the Campaign for Tobacco-Free Kids advocacy group, said in a telephone interview. "This is an industry that has a history of targeting kids because they know that's when everybody starts," he added. Among adolescent boys, the rate of use of smokeless tobacco rose from 3.4 percent in 2002 to 4.4 percent in 2007, according to the report. McGoldrick said the increase occurred as smokeless tobacco companies greatly increased their spending on marketing and introduced a new range of products. The findings reiterated the need for the U.S. Food and Drug Administration to have the power to regulate tobacco products, as legislation being considered by [...]

Charlotte Parker2009-05-19T15:05:12-07:00May, 2009|Oral Cancer News|

ASCO: HPV Infection Linked to Better Outcome in Oropharyngeal Cancer

Source: MedpageToday.com Author: Michael Smith TORONTO, May 14 -- Patients with oropharyngeal cancer had a 50% lower five-year mortality risk when they also had human papillomavirus (HPV) infection, according to data from a randomized clinical trial. HPV-positive patients had a two-year overall survival of 88% compared with 66% for HPV-negative patients (P<0.001), said Maura Gillison, M.D., of Ohio State University in Columbus. The difference between groups increased with follow-up. HPV infection also was associated with a reduced risk of locoregional recurrence and second cancers, Dr. Gillison reported at a press briefing in advance of the American Society of Clinical Oncology annual meeting. Cancer of the oropharynx arises from two principal causes: chronic use of tobacco and alcohol or HPV infection. Previous studies had suggested that HPV status of a patient's tumor might have prognostic implications. "HPV-positive patients have important associations with other favorable prognostic factors," said Dr. Gillison. "They tend to be younger; they have smaller tumors; they present with better performance status. Therefore, improvement in survival for this patient population may be explained by these factors and not by HPV." To explore the role of HPV status in survival of oropharyngeal cancer, Dr. Gillison and colleagues reviewed data from a randomized clinical trial conducted by the Radiation Therapy Oncology Group. Its principal objective was to compare standard chemotherapy with an investigational regimen. The trial involved 721 patients. Of those, 60% had cancer of the oropharynx and 64% were HPV positive. The two-year results demonstrated a clear survival advantage associated [...]

Charlotte Parker2009-05-15T16:11:18-07:00May, 2009|Oral Cancer News|

Spit tobacco is not a quit-smoking solution

Source: News-record.com Author: Tead Eaves What do you think? Dr. Brad Rodu recommends spit tobacco use as a method to help with smoking cessation ("Smokers need the facts on alternatives," Ideas, April 19). This strategy, known as harm reduction, encourages spit tobacco as an alternative to cigarettes because of lower risks for severe health consequences. Although smoking cessation is very important, spit tobacco is not a safe alternative. There are numerous diseases and illnesses that have been scientifically linked to spit tobacco, including gingivitis, tooth decay, cardiovascular disease and oral, esophageal, pharyngeal, laryngeal, stomach and pancreatic cancer. The most dangerous of these health issues is oral cancer, which has a mortality rate of 54 percent within five years of diagnosis. The risk for developing oral cancer from spit tobacco has been found to be 14 times greater than the risk in nonusers. Besides the health risks associated with the use of spit tobacco, there are other concerns with harm reduction. There could be an increase in use among adolescents who think "smokeless is harmless" when it comes to spit tobacco, an overall increase in the use of tobacco by nonusers, and an increase in sales of high-nicotine products that raise the risk for addiction. In his research, Dr. Rodu has often discussed the effectiveness of harm-reduction programs in Sweden. While Swedish studies have indeed demonstrated decreased smoking levels through the use of spit tobacco, there are several differences between the two countries that make it difficult to compare the United [...]

Charlotte Parker2009-04-27T16:40:12-07:00April, 2009|Oral Cancer News|