Should You Get the HPV Vaccine?

You don’t have to be a virgin to be protected against cancer. By Jake Blumgart|Posted Friday, Jan. 25, 2013, at 1:22 PM ET Source: Slate A doctor gives a 13-year-old girl an HPV vaccination Photo by Joe Raedle/Getty Images. The human papillomavirus has the dubious distinction of being the sexually transmitted disease you are most likely to get. It’s also the leading cause of cervical cancer. January has, somewhat arbitrarily, been dubbed Cervical Health Awareness Month (also National Hobby Month and Hot Tea Month, the last at least for good reason). While cervical cancer is the disease most commonly associated with HPV, a recent report from the American Cancer Society emphasizes that HPV’s threat is not gender-specific or organ-specific. While cervical cancer cases are in decline (as are general cancer rates), cancers linked to HPV are on the rise. The increasing prevalence of HPV-linked cancers should permanently alter our limited conception of the disease as chiefly a women’s issue. Oropharyngeal (which I’ll be vulgarizing as “oral”) and anal HPV-related cancers (which particularly afflict men who have sex with men) are becoming more common. Oral malignancies account for 37.3 percent of HPV-related cancers, edging out cervical cancer, which makes up 32.7 percent. For men, oral cancers make up 78.2 percent of total HPV-related cancer incidences, and they account for 11.6 percent of cases among women. The death rate for oral cancer is three times higher than that for cervical cancer. (About 40 percent of penile cancer cases are HPV-related, but rates [...]

2013-01-28T14:28:34-07:00January, 2013|OCF In The News, Oral Cancer News|

A tragic turn of events to most important dental story published in 2012

Source: DentistryIQ Date: 12/21/2012 By Maria Perno Goldie, RDH, MS, and Jo-Anne Jones, RDH Jo-Anne Jones, RDH, President, RDH Connection Inc., has much to be proud of! An article by Jo-Anne, about a possible connection between sex and oral cancer, has been selected by the dental editors of PennWell publications as the most important article published in 2012 for the dental profession. Jones’ article, “Sex and oral cancer: What is the connection?” appeared in the April 6 issue of RDH eVillage FOCUS e-newsletter. The article shares some of the latest statistics regarding a possible connection between the human papillomavirus (HPV) and oral cancer. To read the article, click here. The editors participating in the selection of the top published dental story perform editorial duties for Dental Economics, RDH, and Proofs magazines, as well as Dental Assisting Digest, RDH eVillage, RDH eVillage FOCUS, DE Expert Tips & Tricks, Surgical-Restorative Resource, and New Products electronic newsletters. Articles that were published in either print or electronic formats were accepted. Dental editors were asked to submit a nomination of the most important article from their respective publication. Nominations were sought for the following categories: • Most important article from Dental Assisting Digest • Most important article from Proofs • Most important article from RDH eVillage • Most important article from RDH eVillage FOCUS • Most important article from New Products • Most important article from Surgical-Restorative Resource • Most important article from DE Expert Tips & Tricks • Most important article from DentalEconomics.com • [...]

2012-12-21T10:56:21-07:00December, 2012|OCF In The News, Oral Cancer News|

Actor Michael Douglas Partners With Oral Cancer Foundation For Early Detection PSA Campaign

LOS ANGELES, May 14, 2012 /PRNewswire-USNewswire/ -- Actor and producer Michael Douglas has donated his time to help create a television public service announcement (PSA) on behalf of the Oral Cancer Foundation (OCF), a non-profit organization dedicated to helping those affected by the disease. The PSA will support the Foundation's efforts to educate the public about the need for annual screenings to catch oral cancers in their early, most survivable stages. The public service announcement will begin airing in June, and will continue to air nationwide through summer and autumn. Approximately 40,000 people in the US will be newly diagnosed with oral cancer in 2012. This includes those cancers that occur in the mouth itself, in the very back of the mouth known as the oropharynx, and on the exterior lip of the mouth. There are two distinct pathways by which most people come to oral cancer. One is through the use of tobacco and alcohol, and the other is through exposure to the HPV-16 virus (human papilloma virus version 16), a newly identified etiology, and the same virus which is responsible for the vast majority of cervical cancers in women. While oral cancer has historically been linked to tobacco and alcohol use, this is not simply a smoker's disease any longer. New data shows that the fastest-growing segment of newly diagnosed cases is now young, non-smokers. Most startling, is the fact that while many other cancers have been in decline in recent years, the occurrence of oral / oropharyngeal [...]

2012-05-14T19:59:49-07:00May, 2012|OCF In The News, Oral Cancer News|

Oral Cancer Foundation Sponsors 13th Annual Oral Cancer Awareness Month in April 2012

Source: Dentistry IQ Organization encouraging dental professionals to offer free screenings to the public Did you know that the fastest growing segment of the oral cancer community is young, healthy non-smokers? It's shocking but true. Exposure to the HPV-16 virus, the most common sexually transmitted infection, is now the leading cause of oral cancers in the U.S. There is little that can be done to stop this virus from spreading. Our only hope to save lives is through increased professional involvement and public awareness to generate early discovery of the disease process. To that end, the Oral Cancer Foundation (OCF) is encouraging the dental community to get involved in Oral Cancer Awareness Month this April 2012 by offering free oral cancer screenings to the public in a national effort to raise awareness of this silent killer. Oral cancer has existed outside the consciousness of much of the public, which is one reason 37,000 Americans will be newly diagnosed this year alone. That is about 100 new people a day. That lack of awareness has contributed to this cancer not being discovered until very late in its development. By implementing a public awareness campaign, OCF wants to educate the public about the risk factors, early signs and symptoms of the disease, as well as the need for all adults to undergo an annual oral cancer screening. In the early stages of oral cancer's development, it is often is painless, and physical signs may not be obvious to an individual. This makes [...]

2012-01-07T16:54:51-07:00January, 2012|OCF In The News, Oral Cancer News|

Data Published in the Lancet Oncology Support High Efficacy Previously Demonstrated By Cervarix

Source: Therapeutics Daily Author: Staff LONDON, Nov. 9, 2011-An analysis published today in The Lancet Oncology reinforces previous findings showing that GlaxoSmithKline’s Cervarix®, provided protection against advanced precancerous lesions (CIN3+), above that expected from a vaccine that protects against human papillomavirus (HPV) types 16 and 18. CIN3+ is the immediate step before invasive cervical cancer and data showing protection against this type of lesion are considered the most stringent evidence of potential cervical cancer prevention.1 Results from the largest efficacy trial of a cervical cancer vaccine to date (PATRICIA), show that Cervarix provided 93%† efficacy against CIN3+ irrespective of the HPV type associated with the CIN3+ lesion.1This pre-defined, exploratory analysis was conducted in women with no evidence of past or current HPV infection.‡ These women are thought to be representative of young girls prior to the onset of sexual activity – the primary target population for organised vaccination programmes. These findings have been incorporated into the European label for Cervarix, updated by the European Commission in September 2011. Additional data from the same end-of-study analysis have been published in a separate article in TheLancet Oncology. These data demonstrate that Cervarix provided 82%* efficacy against CIN3+, associated with a composite of 12 cancer-causing HPV types not included in the vaccine, in the same population as the analysis discussed above.2 This analysis excluded cases co-infected with HPV 16 and/or 18 and is therefore a conservative estimate of cross-protective efficacy. Non-vaccine HPV types, including the 12 studied in this analysis, together account for approximately 30% of cervical cancers globally.3 The authors [...]

2011-11-16T12:04:02-07:00November, 2011|Oral Cancer News|

Life After Tongue Cancer, & a Total Glossectomy

Source: UCSF Medical Center Author: Sierra Tzoore   Tongue cancer is uncommon, and it's especially unusual for it to strike a young person who doesn't smoke or drink heavily. Kate Brown was just 32 years old, recently married and beginning a new job, when she learned that a spot on her tongue was stage III tongue cancer. Brown was referred to UCSF Medical Center, where surgeons recommended a drastic treatment that was her best shot at survival: a total glossectomy, or tongue removal, followed by chemotherapy and radiation. Four years later, Brown is cancer-free and, unlike many patients who undergo total glossectomy, able to eat and speak understandably. We asked Brown about her treatment and path to recovery. How did you discover you had tongue cancer? A small sore appeared on my tongue when I had a sore throat. I took antibiotics for the sore throat, but the spot was still there after the sore throat subsided. I then started to have ear pain and the sore got larger. I was prescribed antibiotics again. When my doctor looked in my ear she didn't see any swelling, but the earache became unbearably painful. I'd never been in pain like that. In my heart of hearts, I knew at that point that something was terribly wrong, but I wasn't sure what it was. I decided to see another doctor, who referred me to an ear, nose and throat specialist, Dr. Ivor Emanuel at California Pacific Medical Center. Dr. Emanuel's specialty is allergies but I think [...]

2011-08-22T12:33:47-07:00August, 2011|OCF In The News, Oral Cancer News|

Ischemic Stroke, Transient Ischemic Attack after Head & Neck Radiotherapy

Source: AHA Journals Author: Chris Plummer, PhD; Robert D. Henderson, PhD; John D. O'Sullivan, MD; Stephen J. Read, PhD Abstract Background and Purpose—Cerebrovascular disease can complicate head and neck radiotherapy and result in transient ischemic attack and ischemic stroke. Although the incidence of radiation vasculopathy is predicted to rise with improvements in median cancer survival, the pathogenesis, natural history, and management of the disease are ill defined. Methods—We examined studies on the epidemiology, imaging, pathogenesis, and management of medium- and large-artery intra- and extra-cranial disease after head and neck radiotherapy. Controlled prospective trials and larger retrospective trials from the last 30 years were prioritized. Results—The relative risk of transient ischemic attack or ischemic stroke is at least doubled by head and neck radiotherapy. Chronic radiation vasculopathy affecting medium and large intra- and extra-cranial arteries is characterized by increasing rates of hemodynamically significant stenosis with time from radiotherapy. Disease expression is the likely consequence of the combined radiation insult to the intima-media (accelerating atherosclerosis) and to the adventitia (injuring the vasa vasorum). Optimal medical treatment is not established. Carotid endarterectomy is confounded by the need to operate across scarred tissue planes, whereas carotid stenting procedures have resulted in high restenosis rates. Conclusions—Head and neck radiotherapy significantly increases the risk of transient ischemic attack and ischemic stroke. Evidence-based guidelines for the management of asymptomatic and symptomatic (medium- and large-artery) radiation vasculopathy are lacking. Long-term prospective studies remain a priority, as the incidence of the problem is anticipated to rise with improvements in [...]

2011-08-08T12:12:22-07:00August, 2011|Oral Cancer News|

Sentinel Node Biopsy Safe & Effective in Head/Neck Melanomas

Source: MD News Author: Staff *see below University of Michigan study refutes controversy about technique in delicate head, neck region. ANN ARBOR, MI — A common technique for determining whether melanoma has spread can be used safely and effectively even in tumors from the head and neck area, according to a new study from the University of Michigan Comprehensive Cancer Center. Sentinel lymph node biopsy involves injecting a special dye to identify the first node where cancer would likely spread. If that node is clean, patients can avoid further debilitating surgery to remove multiple lymph nodes. If that node shows cancer, patients know they need the more extensive surgery or further treatment with radiation, chemotherapy or a clinical trial. Patients with larger melanomas are routinely offered this procedure. But many surgeons believed that the complex anatomy combined with the critical nerves and blood vessels in the head and neck area made sentinel lymph node biopsy unsafe and inaccurate for melanomas in that region. In the current study, which appears online in Cancer, researchers looked at 353 head and neck melanoma patients who had received sentinel lymph node biopsy at U-M over a 10-year period. After reviewing patients’ records, the researchers found that the sentinel lymph node could be identified in all but one patient, and no patients sustained permanent nerve injuries during the procedure. About 20 percent of the patients had at least one sentinel node positive for cancer and were referred for a complete dissection to remove additional lymph [...]

2011-08-08T12:12:51-07:00August, 2011|Oral Cancer News|

AAOMS Supports Goals of Oral Cancer Awareness Week

ROSEMONT, Ill., April 1, 2011 /PRNewswire-USNewswire/ -- The 2011 Oral Cancer Awareness Week, set for April 11-15, is intended to educate people of all ages and socio-economic levels about the risk factors and symptoms of oral, head and neck cancer and the importance of early detection. The American Association of Oral and Maxillofacial Surgeons (AAOMS) agrees with the Oral Cancer Foundation, which conceived the awareness week observance, that it is critical oral cancers receive the national media attention necessary to raise public awareness. The Oral Cancer Foundation points out that the high death rate traditionally associated with oral cancer is not because it is hard to discover or diagnose, but because the cancer has historically been discovered late in its development.  In its early stages, oral cancer may – and often does - go unnoticed because there are no blatant symptoms or pain.  This only underscores the importance of establishing a regimen to include regular self-examinations and examination by a dentist or oral and maxillofacial surgeon at least annually. The mouth is one of the easiest parts of your body to examine yourself. Also, changes in the mouth can be easily seen, so oral cancer can be detected in its early stages. The key to early detection is performing a self-examination regularly. Examining your mouth each month will help you identify changes or new growths early. And, early detection is important in increasing the chance of a cure. Factors That May Cause Cancer According to the National Institutes of Health, [...]

HPV: To test or not to test

Source: www.rdhmag.com Author: Nancy W. Burkhart, RDH, EdD The dental practitioner has a responsibility to examine and assess the oral tissue status of all patients. Usually, we are happy to report that the tissue is healthy and no further treatment is necessary. Ethically, our role in assessment is both an understood practice as well as a legal one each time we interact with our patients. Within your practice, what is the expected role in assessing and relaying advice/recommendations to our patients? Do we rely strictly on scientific evidence with evidence-based protocol? Do we trust the developers/promoters of dental products to provide information to us? Do we relay personal opinion from colleagues, or do we reject opinion-based information? Do we search the scientific literature for current information, or call our colleagues and company representatives and obtain a consensus of what the best options may be for dissemination of information? We have all been in these situations. With busy practices, it is very time consuming to sit down and evaluate all the literature. Anyone who has been faced with a medical decision for a loved one or ourselves may actually feel exhausted while trying to sort through all of the options, treatments, and advice – some of which may even be at odds within specific group specialties in the way treatment is rendered. It can be very daunting, draining us both mentally and physically. So how do we approach this dilemma? For some time, we have known about the detrimental [...]

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