MRI – Page 2 – Oral Cancer News

MRI shows promise for oral cancer staging

Source: www.drbicuspid.com Author: DrBicuspid Staff Magnetic resonance imaging (MRI) could play an important role in the diagnosis of oral cancer, according to a study in Brazilian Oral Researcher (December 2011, Vol. 25:6, pp. 512-518). Researchers from the University Center of Anapolis School of Dentistry compared clinical staging and MRI staging for oral cancer in 10 patients diagnosed with oral cancer. A head and neck surgeon performed standard TNM staging, while two medical radiologists and two oral radiologists performed a new staging assessment by interpreting MRI studies, without prior knowledge of the clinical staging. Each evaluated the extent of the primary tumor (T), metastasis to regional lymph nodes (N), and grouping by stages. There was significant agreement (p

Oral Cancer Foundation News Team - A2011-12-09T06:53:40-07:00December, 2011|Oral Cancer News|

MRI can show jaw invasion of oral cancer

Source: www.medpagetoday.com Author: Charles Bankhead, Staff Writer Oral cancer's spread to the mandible could not hide from a type of MRI that may facilitate more accurate staging and surgical planning, data from laboratory studies suggest. Sweep imaging with Fourier transform (SWIFT) provided fine-detail views of cortical and medullary bone specimens, and the images exhibited good correlation with histopathologic findings. The in-vitro studies did not specifically examine SWIFT's ability to identify early cortical bone invasion by oral cancer. However, the high-quality images obtained from the investigation provide reason for optimism, the researchers reported in the September issue of Archives of Otolaryngology Head and Neck Surgery. "Our study is very promising in that it offers a SWIFT-based MRI technique for accurate assessment of minute changes of cortical and medullary bone in three dimensions without any ionizing radiation," Ayse Tuba Karagulle Kendi, MD, of the University of Minnesota in Minneapolis, and co-authors wrote. "It has the potential to precisely determine the extent of mandibular bone invasion associated with oral carcinoma. This study is a crucial step toward the goal of developing a robust and noninvasive approach for preoperative imaging of mandibular invasion," they added. Carcinoma of the oral cavity often spreads to the mandible, but in many instances does not cross the periosteal layer, obviating the need for mandibulectomy. Limitations of current imaging techniques often preclude determination of bone invasion prior to surgery, the authors noted. MRI and CT have been used most often to evaluate mandibular invasion of oral cancer, but conventional [...]

Oral Cancer Foundation News Team - A2011-09-23T16:35:59-07:00September, 2011|Oral Cancer News|

Ultrasound as effective as CT scans for most diagnoses, reducing the dangers of radiation

Source: www.medicalnewstoday.com Author: staff For diagnosing head and neck ailments, tests that use radiation are always less desirable than those that don't. Otolaryngologists have a wide range of techniques available to them, including CT or "CAT" scans, MRI and ultrasound. CT uses significant radiation and MRI a lower amount, but ultrasound is a non-invasive, non-radiating technique. It does not require injection of radioactive contrast material and has no side effects. Now, a new study by Tel Aviv University exploring the efficacy of expensive and invasive CT scans has found that, in some cases, they don't offer a clinical advantage over a simple, inexpensive ultrasound procedure. In his study, Dr. Michael Vaiman of Tel Aviv University's Sackler Faculty of Medicine compared the efficacy of CT versus ultrasound scans for locating vertebral arteries in the throat, an important assessment that must be completed before a surgeon operates in the neck area of the body. After comparing the outcomes of 250 CT scans with 500 ultrasound images, he concluded that there is no advantage to using CT scans for most of these procedures, especially those that are used to locate anomalies in the neck to map major arteries before surgery can take place. Dr. Vaiman's results were published in the March issue of the European Archives of Oto-Rhino-Laryngology. When scans are sound CT scans combine X-rays with highly sophisticated computers to produce a number of pictures of the interior of the body. Traditionally, doctors have relied on these scans to find neck arteries [...]

Oral Cancer Foundation News Team - A2011-05-13T12:21:24-07:00May, 2011|Oral Cancer News|

More ’empowered’ patients question doctors’ orders

Source: www.usatoday.com Author: Mary Brophy Marcus In the past, most patients placed their entire trust in the hands of their physician. Your doc said you needed a certain medical test, you got it. Not so much anymore. Jeff Chappell of Montgomery, Ala., recalls a visit a couple of years ago to a Charlotte emergency room, near where the family used to live, with his wife, Jacqueline, who has adrenal failure. "I blew up loud enough for everyone in the ER to hear me explain that while we were insured, an MRI was about a $1,000 co-pay," Chappell says. The couple knew her symptoms well (primarily stomach pain), knew that an MRI was not necessary under the circumstances and knew that a cortisone shot was what she needed. "The doctor walked off in a huff," Chappell says, but later came back and "compromised" by agreeing to give his wife the shot, but not before taking an abdominal X-ray to rule out other problems first. Many physicians say an increasing number of patients are getting involved in decisions about their medical care, including medication choices, whether they need a specialist, and especially whether they need expensive diagnostic tests, which some health economists say are driving up the cost of health care. 'Shared decision model' "There have been big changes," says Patrick McManus, residency director of family and community medicine at Thomas Jefferson University in Philadelphia. "Some of my older patients are still more deferential, but more and more, we talk with patients [...]

Oral Cancer Foundation News Team - A2010-09-03T20:58:23-07:00September, 2010|Oral Cancer News|

PET-FDG improves staging, management of head, neck cancer

Source: helathimaging.com Author: staff Adding whole-body PET-FDG to the pre-therapeutic conventional staging of head and neck squamous cell carcinoma improved the TNM [tumor, node and metastasis] classification of the disease and altered the management of 13.7 percent of patients, according to a study published in the February issue of the Journal of Clinical Oncology. Max Lonneux, MD, from the departments of nuclear medicine, head and neck surgery, radiation oncology and maxillofacial surgery, Cliniques Universitaires Saint-Luc in Brussels, and colleagues included his 233 patients in this multicenter, prospective study with newly diagnosed and untreated head and neck squamous cell carcinoma. Researchers first determined the TNM stage and therapeutic decision based on the conventional work-up (including physical exam, CT/MRI of the head and neck region, and thoracic CT) and sealed in envelope. They then performed whole-body PET-FDG, and subsequently wrote TNM stage and therapeutic decision in a sealed envelope. The investigators also recorded changes in TNM stages and in patient management as a result of PET-FDG imaging. Clinical outcome and histopathology were used as gold standards to validate the TNM stage. Conventional and PET stages were compared using the McNemar test. According to the authors, conventional and PET stages were discordant in 43 percent of the patients. PET proved to be accurate in 47 patients and inaccurate in 13 patients. TNM status was left unconfirmed in 40 patients because no therapeutic change was expected from the stage difference. The researchers found that conventional plus PET TNM classification (envelope two) was significantly more [...]

Oral Cancer Foundation News Team - A2010-02-17T08:18:31-07:00February, 2010|Oral Cancer News|

Nanomagnet in “Star-Trek style” wand could cure cancer

Source: www.telegraph.co.uk Author: staff The space-age technology, which uses microscopic iron particles to heat up and destroy tumours, may be ready for clinical trials in as little as three years. Different teams of UK scientists have been working together on the research, which could bring new hope to patients who are no longer responding to standard therapy. In future the ''nanomagnet'' cancer treatment may even be administered in GP surgeries or out-patient clinics. Crucially, the scientists believe it will be highly cost-effective. The technique literally ''cooks'' cancer cells as if they were in a microwave oven. But instead of microwaves, a rapidly changing magnetic field is generated by the paddle-shaped ''wand''. This heats up thousands of iron oxide ''nanoparticles'' placed inside the tumours. Heating the cells by only 5-6C is enough to send them into shock and kill them. Meanwhile, surrounding healthy tissue in which the iron oxide particles are absent is left unharmed. A major part of the research has involved finding ways to target tumours with the nanoparticles. Two approaches have been explored, one using bone marrow stem cells and the other using antibodies to ferry the particles to cancer sites. A major advantage of using a biological version of ''iron filings'' in the therapy is that they can easily be tracked by a magnetic resonance imaging (MRI) scanner. Doctors will be able to map exactly where the nanoparticles - and the cancer - are situated in the body. The ''wand'' can then be held over the hidden [...]

Oral Cancer Foundation News Team - A2009-10-06T20:29:12-07:00October, 2009|Oral Cancer News|

Oxygen and MRI may determine best cancer treatment

Source: www.allheadlinenews.com Author: David Goodhue A combination of a basic magnetic resonance imaging, or MRI, test and breathing oxygen may determine the best course for treating some cancer patients, University of Texas, Southwestern researchers said. Researchers have demonstrated before that the amount of oxygen present in a tumor can be a predictor in its response to treatment. Tumors with little oxygen typically grow stronger and are resistant to chemotherapy and radiation. But the only way to measure the oxygen level in tumors was to insert a large needle directly into the growth. Dr. Ralph Mason, a professor of radiology at the University of Texas, Southwestern, said a technique known as a blood oxygen level dependent, or BOLD, MRI, can detect oxygen levels in tumors noninvasively. The patient only has to breathe oxygen when undergoing the MRI, according to a UT Southwestern press release. "The patient simply inhales pure oxygen, which them circulated through the bloodstream, including to the tumors," Mason said in a statement. A report of Mason and his colleagues' research will appear in a future edition of Magnetic Resonance in Medicine. BOLD MRIs are not new to the medical profession. They have been used extensively in studying brain function. Doctors at UT Southwestern have begun using them to treat patients with cervical, prostate and head and neck cancers.

Oral Cancer Foundation News Team - A2009-06-03T04:48:29-07:00June, 2009|Oral Cancer News|