Global burden of cancer is on the rise

Source: Medical News TodayPublished: Catherine Paddock, PHDBy: February 4, 2014  A new report from the World Health Organization's cancer agency reveals that cancer rates are growing at an "alarming pace" around the world and urges stronger efforts on prevention measures to curb the disease. The World Cancer Report 2014, from the World Health Organization's (WHO's) International Agency for Research on Cancer (IARC), estimates that the global burden of cancer will rise from an estimated 14 million new cases per year in 2012 to 22 million within the next 20 years. Due to growing and aging populations, developing countries are disproportionately affected by the growing numbers of cancers. Over 60% of the global burden is in Africa, Asia and Central and South America, where 70% of cancer deaths occur, and where lack of early detection and treatment is a growing problem. There is an urgent need to put in place measures to prevent the disease, says the report, adding that half of all cancers could be avoided if we use what we already know more effectively. Dr. Christopher Wild, report co-editor and director of the IARC, says: "Despite exciting advances, this Report shows that we cannot treat our way out of the cancer problem. More commitment to prevention and early detection is desperately needed in order to complement improved treatments and address the alarming rise in cancer burden globally." Leading cause of deaths worldwide, costs spiralling out of control Cancer is a leading cause of death worldwide - in 2012 the [...]

2014-02-06T14:44:36-07:00February, 2014|Oral Cancer News|

What the ‘rinse-and-spit’ oral cancer test could mean for dental professionals and their patients

Source: Author: Vicki Cheeseman, Associate Editor A new oral cancer “rinse-and-spit” test for the early detection of tumors could mean great things for dental professionals and their patients when the test becomes available for use in dental practices nationwide possibly as early as late 2014 or into 2015. The test, developed at the University of Miami Miller School of Medicine and exclusively licensed to Vigilant Biosciences, Inc., will be available as a low-cost, point-of-care screening test for the early detection of oral cancer, and is envisioned as a kit with a special oral rinse and test strip. The test strip detects proteins that are markers of oral cancer and are captured by the rinse. The markers may be present before a lesion is easily visible. Early detection tests are critical because the majority of patients present in late stage when cure rates reach only 40%. I asked Dr. Franzmann to explain how the test strip works. “The beauty of the test strip approach is that it is so simple for the patient and health-care professional to use. The technology behind the test strips has been around for many years and is used for many medical applications. The key is to know what to test for. Through our research, we discovered certain proteins, or markers, are present in the saliva in the early stages of squamous cell carcinoma, the most common head and neck cancer.” How early can tumors be detected with the test strip? Dr. Franzmann said, “The tumors [...]

If You Fail to Look

Source: The American Academy of Oral Systemic Health Newsletter Author: Cris Duval Detecting oral cancer in its earliest stages saves lives, eases suffering, reduces morbidity, and ameliorates post-surgery recovery. Remember when you took driver’s education in high school?  I do! When I grew up, driver’s education students in Washington State were required to watch “shock” highway-safety films. These videos, depicting the aftermath of drivers’ actions, showed actual accident scenes, complete with audio recordings of victims’ screams and color close-ups of mangled bodies.  My bet is that, if you have ever watched one of these videos, you have never forgotten it. For me, when I saw these videos, I thought about my family and my friends.  I know that I have a family that loves and cares about me, and thus, I owe it to them to avoid doing something stupid behind-the-wheel.  I never want one of my loved ones to have to go through the pain of seeing me hurt. This means to me that my driver’s license is more than just a “key” to get behind the wheel.  Rather, as a website for traffic safety in Texas states, a driver’s license signifies that the driver possesses the “essential knowledge, skills, and experience to perform reduced risk practices in [a] total traffic environment.”  In other words, the driver is accountable to himself and other drivers. My response to these driver’s education videos is akin to my reaction to videos that I watched at the Pacific Northwest Head, Neck & Thyroid Cancer [...]

2012-06-01T09:35:08-07:00June, 2012|Oral Cancer News|

Ireland: mouth cancer awareness day yields results

Source: Author: staff Dentists are emphasizing the importance of early detection with mouth cancer, after 12 cases of the potentially deadly cancer were discovered on Mouth Cancer Awareness Day and one of these was discovered in Waterford. The Irish Dental Association estimates that 10,000 people availed of free mouth cancer examinations carried out by participating dentists countrywide on September 21 of last year. As well as the confirmed cases, 286 people were advised to attend their GP for other related problems. Mouth Cancer Awareness Day was set up by a group of mouth, head and neck cancer survivors in September 2010. It is now a joint initiative by the Irish Dental Association, Irish Cancer Society, Dublin Dental University Hospital, Cork Dental University Hospital, the Dental Health Foundation and Mouth, Head and Neck Cancer Awareness Ireland. The President of the IDA, Conor McAlister said the fact twelve cancers were discovered in one day showed the importance of early detection and the need for everyone to have a regular examination. He said, "Three hundred cases of mouth cancer are detected here each year with 100 deaths and this type of cancer actually kills more Irish people than cervical cancer or skin melanoma. "According to the National Cancer Register in Ireland, roughly 50% of all mouth cancers are diagnosed at an advanced stage. Hopefully the fact these 12 cases have been caught at an earlier stage means the impact on quality of life will be reduced." He added, "This year we saw [...]

Oral temperature changes in head and neck cancer patients predicts side effect severity

Source: American Society for Radiation Oncology The abstract, "Pilot study of functional infrared imaging for early  detection of mucositis in locally advanced head and neck cancer  reated with chemoradiotherapy," will be presented at the Head and  neck Society Meeting in Arizona today. This is a synopsis of that  presentation. Slight temperature increases of the oral mucus membranes early in a head and neck cancer patient's chemotherapy and radiation therapy (chemoradiotherapy) treatment is a predictor of severe mucositis later in treatment, according to a study presented at the Multidisciplinary Head and Neck Cancer Symposium, sponsored by AHNS, ASCO, ASTRO and SNM. Mucositis, or mouth sores, is a common side effect of chemoradiotherapy for head and neck cancer that is painful and can be very severe. Physicians cannot predict which patients will have mild mucositis or severe mucositis that would require narcotic pain  medication, nutritional support and/or feeding tubes. Researchers in this study hypothesized that using sensitive thermal imaging technology to measure temperature changes of less than  one-tenth of a degree early in treatment could predict the severity of mucositis later in treatment. This knowledge could allow for early  intervention and potential changes in therapy using a technology that is simple, harmless and non-invasive. Patients receiving chemoradiotherapy underwent baseline and weekly thermal imaging of their oral mucus membranes. All patients displayed an increase in temperature and severe mucositis was found in 53 percent of patients. "If we could predict which patients were going to suffer the greatest toxicity, we could proactively make changes to [...]

2012-01-26T15:32:36-07:00January, 2012|Oral Cancer News|

Johnson & Johnson Sued for $70 Million Over Oral Cancer Test Detection

Source: July 8, 2011 -- Oral Cancer Prevention International (OCPI), makers of the Oral CDx brush test for oral cancer detection, is suing Johnson & Johnson (J&J) over a terminated distribution contract with OraPharma. OraPharma was previously a subsidiary of J&J until it was acquired last December by Water Street Healthcare Partners, a private equity firm in Chicago. J&J, which among other things sells Listerine mouthwash, was worried that a 2008 study linking alcohol-containing mouthwashes with oral cancer would negatively affect sales of Listerine and allegedly induced OraPharma to breach the sales agreement, according to OCPI. The lawsuit, filed July 6 in U.S. District Court, District of New Jersey, claims that J&J "maliciously and fraudulently" interfered with a contract between OCPI and OraPharma that gave OraPharma exclusive rights to sell the test to U.S. dentists. J&J's interference caused OraPharma "to suppress sales of and withhold from the public a proven lifesaving oral cancer prevention product in order to protect sales of its mouthwash, Listerine, which has been linked to oral cancer," according to the complaint. After OCPI signed the contract in February 2010, J&J did not want to "lend credence to the link between Listerine and oral cancer" by selling both its mouthwash and OralCDx, the complaint states. As of press time, J&J did not return calls for comment by Sales of Listerine bring in more than $1 billion per year, the suit claims. OralCDx is a "quick, painless, and inexpensive test that can prevent oral cancer by [...]

Oral, Head and Neck Cancers Continue to Increase While Most U.S. Cancer Death Rates are on the Decline

Source: SHOTS (NPR's Health Blog) The rate at which Americans die from cancer continues to fall, according to the latest estimates from the American Cancer Society. As a result, nearly 900,000 cancer deaths were avoided between 1990 and 2007, the group figures. Survival gains have come as mortality rates have declined for some of the most common malignancies, including colorectal cancer, breast cancer in women and prostate cancer. Still, the ACS estimates there will nearly 1.6 million new cancers diagnosed this year, and about 572,000 deaths from the disease. The incidence of cancers hasn't budged much for men in recent years, after falling quite a bit during the first half of the last decade. Cancer incidence for women has been falling since 1998. The report was just published online by CA: A Cancer Journal for Clinicians. Lung cancer remains the biggest killer for both men and women. All told, about 160,000 people in the U.S. are expected to die from it this year. Starting in 1987, more women have died from lung cancer each year than breast cancer. One section of the report focuses on a persistent and, in some cases, widening gap in cancer death rates between people with the least education and those with the most. Educational attainment is often used in research as a proxy for socioeconomic status. American Cancer Society epidemiologist Elizabeth Ward, one of the report's authors, tells Shots, "People of a lower socioeconomic status are more likely to smoke and less likely to get [...]

Oral Cancer Foundation breaks records in April’s Awareness and Screening Month

Source: MSNBC News Author: staff Oral cancer is an insidious disease that too often is not discovered until very late in its development, as it might not produce symptoms the average person may notice. By then treatments are less effective, and because of late discovery in far too many patients, it has a five year survival rate of only about 57%, much lower than cancers we commonly hear about. Oral cancer has existed outside the awareness of much of the public, yet it will take one life, every hour of every day in the U.S. This year the combination of unprecedented efforts by the relatively small, non-profit Oral Cancer Foundation, a coalition of strategic partners they formed, and a dose of celebrity power, created what might be called a perfect storm; and one that potentially will change public awareness of one of the few cancers that is actually increasing in incidence in the U.S. For thirteen years in a row, April has been oral cancer awareness month nationally. More than 85% of all head and neck cancers are oral and oropharyngeal disease. Historically, a loose coalition of stakeholders in the disease has mustered about 200 screening events in April in facilities ranging from large institutions to individual dental offices around the country. Those participants opened their doors for at least a half-day to opportunistically screen members of the public in their communities for free, to find early stage disease, and to raise public awareness. This year the Oral Cancer Foundation, [...]

American Dental Association encourages public to get screened for oral cancer

Source: Author: press release The American Dental Association (ADA) and the Oral Cancer Foundation (OCF) encourage people  to take part in Oral Cancer Awareness Month in April by visiting a dentist for a free oral cancer screening.  So far, more than 1,250 sites across the nation have registered their screening events with the OCF. "Although many dentists perform oral cancer screenings as a routine part of dental examinations, the ADA encourages dentists to go out into their communities during the week of April 11-15 to provide free oral cancer screenings to people who might not regularly visit a dentist," said ADA Spokesperson Sol Silverman, D.D.S., a professor of oral medicine at the University of California, San Francisco. "Early detection is critical in increasing survival rates for patients who have developed an oral cancer; and recognizing and managing precancerous lesions is extremely important in prevention," he said. Mr. Brian Hill, OCF executive director and an oral cancer survivor, also stressed the importance of early detection and the important role that dentists play.  "Early detection is important because it reduces treatment-related morbidity and improves survival rates," he said. In 2010, the National Cancer Institute estimated that approximately 36,540 people were diagnosed with oral cancer and approximately 7,880 people died of oral cancer. The National Institute of Dental and Craniofacial Research (NIDCR) estimates that the five-year survival rate for people diagnosed early, when the disease has not spread beyond the original location, is approximately 83 percent compared to a 20 percent survival [...]

Dental professionals join The Oral Cancer Foundation to raise awareness as HPV is now the primary cause of Oral Cancers in America

NEWPORT BEACH, Calif., April 4, 2011 /PRNewswire/ -- A serious change in the cause of oral cancer is taking place nationally, and its implications are impacting the American public in a manner that a decade ago no one would have predicted. For decades, oral cancer (also known as mouth cancer, tongue cancer, tonsil cancer, and throat cancer) has been a disease which most often occurred in older individuals, who during their lifetimes had been tobacco users.  Most cases were ultimately the result of lifestyle choices. Today that paradigm has changed. A common, sexually transferred virus has replaced tobacco as the number one cause of oral cancers, Human Papilloma Virus number 16 (HPV16). This is one of the same viruses that are responsible for the majority of cervical cancers in women. This year alone, approximately 37,000 Americans will be newly diagnosed with oral cancer, and one person will die every hour of every day from this disease. HPV16, one of about 130 versions of the virus, is now the leading cause of oral cancer, and is found in about 60% of newly diagnosed patients. Dr. Maura Gillison from the James Cancer Center, a long time researcher of the relationship between HPV and oral cancers, recently reported these new findings at the American Academy for the Advancement of Science meeting. This change in etiology, which has accelerated its influence over the last two decades as tobacco use in the US simultaneously was declining, has also changed the demographics of who is getting [...]

2011-04-07T10:39:32-07:00April, 2011|OCF In The News, Oral Cancer News|
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