chemotherapy – Page 10 – Oral Cancer News

Aspirin may stop deafness caused by chemotherapy

Source: www.bbc.com Author: staff Aspirin could save the hearing of cancer patients receiving chemotherapy, scientists in Cardiff hope. A trial will be launched at the city's Velindre Hospital to see if high doses of the drug can prevent permanent loss. Conditions ranging from tinnitus to deafness are a common side effect for patients given the chemotherapy drug cisplatin. The trial, called Coast, has recruited 88 adults prescribed cisplatin in Cardiff and other UK hospitals. It is used to treat testicular cancer, germ cell cancer, head and neck cancer, bladder cancer, cervical cancer, non-small cell lung cancer and some types of children's cancer. 'Shock it was cancer' Father-of-four Andrew Millington, 66, was given cisplatin after a tumour was found at the base of his tongue. "I had a persistent sore throat and earache, and I went to see my GP last spring," he said. "I was referred to a consultant and had an MRI scan. It was a shock to be told it was cancer but... it was generally curable, which was such a relief to hear. I was offered cisplatin and, after hearing about the possible side effects, I was more than happy to take part in the Coast trial." Around 18,500 cancer patients receive cisplatin every year and around half suffer some form of permanent hearing loss. Ahead of the trial's launch on Thursday, professor Emma King, chief investigator and Cancer Research UK surgeon at the University of Southampton, said: "Aspirin can have serious side effects, including internal bleeding, [...]

Oral Cancer Foundation News Team - A2014-05-11T11:18:15-07:00May, 2014|Oral Cancer News|

Jim Kelly’s toughest game: Fighting oral cancer

Source: www.foxnews.com Author: Dr. Manny Alvarez Jim Kelly, the Hall of Fame quarterback who played for the Buffalo Bills until 1996, is one of the greatest football players that I have ever seen. During his football career, I followed him closely and was always in awe of his athletic abilities, his leadership qualities and his love of family. Unfortunately, Jim Kelly is currently battling a second recurrence of oral cancer and has been scheduled to undergo surgery in an attempt to control the disease. His wife, Jill, told the Associated Press that her 54-year-old husband’s cancer is aggressive and beginning to spread. I’ve been following Jim Kelly’s health struggles and have been thinking about him, praying that he gets better. It is easy to think of some humans as immortal – especially when you’re looking at an individual as physically fit as Jim Kelly. But we tend to forget that sometimes nature has a unique plan for all of us. However, Jim Kelly’s struggles can serve as a reminder for us all to be vigilant about our health. Jim Kelly is suffering from oral cancer, which doesn’t get the attention that it deserves, despite the fact that 42,000 new cases will be diagnosed in 2014, according to the National Cancer Institute. Oral cancers are any cancers occurring in the oral cavity, which starts in your throat and extends all the way to your lips. The sad part about this disease is that oral cancers are typically not identified early, which [...]

Oral Cancer Foundation News Team - A2014-03-30T10:22:43-07:00March, 2014|Oral Cancer News|

Unilateral radiation benefited patients with advanced tonsil cancer

Source: www.healio.com Author: staff Unilateral radiotherapy was associated with effective regional control in patients with advanced tonsil cancer, according to study results presented at the 2014 Multidisciplinary Head and Neck Cancer Symposium. Additionally, the results supported previous findings that suggest the primary tumor location, not the extent of ipsilateral neck lymph node involvement on the tumor side of the neck, governs the disease risk in the contralateral side of the neck. Researchers evaluated 153 consecutive patients diagnosed with squamous cell carcinoma of the tonsil who were treated with surgical removal and postoperative intensity-modulated radiation therapy. Forty-six of the patients underwent unilateral radiotherapy. Of these patients, 72% were male. The average patient age was 59 years. Current or former smokers comprised 61% of the study population. Lateralized primary tumors were confirmed in 40 (87%) of the patients. Two (4%) patients had non-lateralized tumors. Lateralization could not be retrospectively ascertained in four patients (9%). The cancer stages for these patients were distributed as follows: TX, 2%; T1, 44%; T2, 41%; and T3, 13%. Lymph node involvement stages were as follows: N0, 11%; N1, 13%; and N2, 76%. The patients underwent radiation doses of 60 Gy to 66 Gy to the postoperative bed and involved neck, and 52 Gy to 54 Gy to the elective region in 30 to 33 fractions using a simultaneous integrated boost technique. Concurrent chemotherapy was administered to 30 of the 46 patients. The median follow-up period was 2.8 years (range, 0.4-8.7 years). Researchers reported no local or regional [...]

Oral Cancer Foundation News Team - A2014-03-26T16:02:26-07:00March, 2014|Oral Cancer News|

Recurrent mouth and throat cancers less deadly when caused by HPV

Source: www.oncologynurseadvisor.com Author: Kathy Boltz, PhD People with late-stage cancer at the back of the mouth or throat that recurs after chemotherapy and radiation treatment are twice as likely to be alive 2 years later if their cancer is caused by the human papillomavirus (HPV), suggests new research. This study was presented at the 2014 Multidisciplinary Head and Neck Cancer Symposium, held in Scottsdale, Arizona. Previous studies have found that people with so-called HPV-positive oropharyngeal cancers are more likely to survive than those whose cancers are related to smoking or whose origins are unknown. The new study shows that the longer survival pattern holds even if the cancer returns. Oropharyngeal cancers, which once were linked primarily to heavy smoking, are now more likely to be caused by HPV, a virus that is transmitted by oral and other kinds of sex. The rise in HPV-associated oropharyngeal cancers has been attributed to changes in sexual behaviors, most notably an increase in oral sex partners. For the study, the researchers used data provided by the Radiation Therapy Oncology Group on 181 patients with late-stage oropharyngeal cancer whose HPV status was known and whose cancer had spread after primary treatment. There were 105 HPV-positive participants and 76 HPV-negative ones. Although the median time to recurrence was roughly the same (8.2 months vs 7.3 months, respectively), some 54.6% of those with HPV-positive cancer were alive 2 years after recurrence, whereas only 27.6% of those with HPV-negative cancers were still alive at that point in time. [...]

Oral Cancer Foundation News Team - A2014-03-19T07:11:24-07:00March, 2014|Oral Cancer News|

Throat cancer survivor celebrates life after trans-oral robotic surgery

Source: www.newswise.com Author: staff When Charlie Guinn sits down to eat with his lovely wife of 39 years, he thoroughly enjoys each bite. It’s not just the food; the entire experience is a celebration. Just over a year ago, Mr. Guinn learned that he had stage IV throat cancer. For him, just surviving would have been an accomplishment — so swallowing again at a meal with a loved one is truly something special. The American Cancer Society estimates that in 2013 over 41,000 people in the U.S. were diagnosed with cancer of the oral cavity and pharynx and almost 8,000 died from the disease. But Mr. Guinn would be the first to say that he is one of the lucky ones. He is one of the first patients to undergo trans-oral robotic surgery (TORS) at the University of New Mexico Hospital. And the results have been stunning. Mr. Guinn first discovered the lump in his throat while shaving. When it was still there a week later, he went to an urgent care center where he was immediately referred to an Ear, Nose and Throat physician. The physician ran a number of tests including a biopsy. When the results came back, the physician referred Mr. Guinn to Nathan Boyd, MD, at the University of New Mexico Cancer Center. It had been only a week and a half from that fateful visit to urgent care. Mr. Guinn recalls, “When I first got there to see Dr. Boyd, one of the nurses told [...]

Oral Cancer Foundation News Team - A2014-03-07T07:25:15-07:00March, 2014|Oral Cancer News|

Surgery beats chemotherapy for tongue cancer, U-M study finds

Source: www.eurekalert.org Author: press release Patients with tongue cancer who started their treatment with a course of chemotherapy fared significantly worse than patients who received surgery first, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center. This is contrary to protocols for larynx cancer, in which a single dose of chemotherapy helps determine which patients fare better with chemotherapy and radiation and which patients should elect for surgery. In larynx cancer, this approach, which was pioneered and extensively researched at U-M, has led to better patient survival and functional outcomes. But this new study, which appears in JAMA Otolaryngology Head and Neck Surgery, describes a clear failure. "To a young person with tongue cancer, chemotherapy may sound like a better option than surgery with extensive reconstruction. But patients with oral cavity cancer can't tolerate induction chemotherapy as well as they can handle surgery with follow-up radiation. Our techniques of reconstruction are advanced and offer patients better survival and functional outcomes," says study author Douglas Chepeha, M.D., MSPH, professor of otolaryngology – head and neck surgery at the University of Michigan Medical School. The study enrolled 19 people with advanced oral cavity cancer. Patients received an initial dose of chemotherapy, called induction chemotherapy. Those whose cancer shrunk by half went on to receive additional chemotherapy combined with radiation treatment. Those whose cancer did not respond well had surgery followed by radiation. Enrollment in the trial was stopped early because results were so poor. Ten of [...]

Oral Cancer Foundation News Team - A2013-12-30T06:42:46-07:00December, 2013|Oral Cancer News|

Swallowing exercises preserve function in head and neck cancer patients receiving radiation

Source: http://www.newsfix.ca/ Author: staff A study at UCLA’s Jonsson Comprehensive Cancer Center has found that head and neck cancer patients receiving radiation as part of their treatment were less likely to need a feeding tube or suffer unwanted side effects such as worsening of diet or narrowing of the throat passage if they performed a set of prescribed swallowing exercises — called a “swallow preservation protocol” — during therapy. The study, conducted from 2007 to 2012, was led by Dr. Marilene Wang, a member of the Jonsson Cancer Center and professor-in-residence in the department of head and neck surgery at UCLA’s David Geffen School of Medicine. The study was published online by the journal Otolaryngology–Head and Neck Surgery, and will appear later in the journal’s print edition. Surgery and radiation have been the traditional treatments for head and neck cancer, but with the advent of improved and targeted chemotherapy, many types of this disease are treated with chemotherapy and radiation, (chemoradiation) in the hope of preserving the tissue and structure. But, even when tissue and structure are preserved, patients do not always retain their ability to swallow naturally and normally. Most patients who receive chemoradiation have significant side effects during treatment and for a long time after recovery. Difficulty swallowing (dysphagia) is one of the most common unwanted side effects of radiation and chemoradiation, and is one of the main predictors of diminished quality of life for the patient after treatment. Wang’s study was designed to evaluate the swallow preservation [...]

Oral Cancer Foundation News Team - A2013-11-19T14:59:39-07:00November, 2013|Oral Cancer News|

Michael Douglas: ‘Throat cancer’ was really tongue cancer

Source: cnn.com Author: Jen Christensen, CNN Michael Douglas never had throat cancer, as he told the press in 2010. The actor now says he had tongue cancer. Douglas said he hid the diagnosis at the urging of his doctor to protect his career. "The surgeon said, 'Let's just say it's throat cancer,' " Douglas told fellow actor Samuel L. Jackson for a segment that ran on British television as a part of Male Cancer Awareness Week. Douglas says that the doctor told him if they had to do surgery for tongue cancer, "it's not going to be pretty. You could lose part of your tongue and jaw." When Douglas first talked about his cancer diagnosis in the summer of 2010, he was on a worldwide publicity tour for the movie "Wall Street: Money Never Sleeps." Douglas and Jackson joked that could have been the end of his acting career. Douglas said if he had surgery he could see the director saying, "What's your good side? I've got no side over here." "There really is no such thing as throat cancer per se," explained Brian Hill, an oral cancer survivor and the founder of the Oral Cancer Foundation. Douglas has taped a public service announcement to raise awareness about oral cancer for Hill's foundation. "Throat" cancer and tongue cancer are both colloquial terms that fall under the oral cancer umbrella. Throat cancer usually refers to cancerous tumors that develop in your pharynx, voice box or tonsils. Tongue cancer refers to cancerous [...]

Oral Cancer Foundation News Team - A2013-10-15T07:17:01-07:00October, 2013|Oral Cancer News|

Eating, Swallowing Exercises May Aid Throat Cancer Patients

Source: US NewsPublished: September 19, 2013 Keeping up these activities during chemo or radiation linked to better diets after treatment, study finds THURSDAY, Sept. 19 (HealthDay News) -- Throat cancer patients appear to benefit from continuing to eat and doing swallowing exercises while undergoing radiation treatment or chemotherapy, researchers say. Radiation treatment can interfere with a person's ability to swallow, but performing swallowing exercises can help patients prevent weakness that can occur after periods of not swallowing. The new study included nearly 500 patients treated for throat cancer between 2002 and 2008. Of the 58 percent of patients who followed swallowing exercises, 74 percent were able to maintain eating at the end of their treatment, the investigators found. In addition, eating and doing swallowing exercises during the treatment period were linked to better long-term diets after treatment ended and less time relying on a feeding tube, according to the study, which was published online Sept. 19 in the journal JAMA Otolaryngology -- Head & Neck Surgery. Long-term swallowing outcomes were best in patients who continued eating throughout radiation treatment or chemotherapy and followed their swallowing-exercise regimen, said Katherine Hutcheson, of the University of Texas M.D. Anderson Cancer Center, and colleagues. Outcomes were worst in patients who did not eat or do swallowing exercises. Nearly 14,000 new cases of throat cancer will be diagnosed in the United States this year, the study authors said in a journal news release. * This news story was resourced by the Oral Cancer Foundation, and [...]

Charlotte Parker2013-09-20T15:02:52-07:00September, 2013|Oral Cancer News|

Swallowing exercises shown to preserve function in head and neck cancer patients receiving radiation

Source: www.healthnewsdigest.com Author: staff A study from UCLA's Jonsson Comprehensive Cancer Center (JCCC) has found that head and neck cancer patients receiving radiation as part of their treatment were less likely to suffer unwanted side effects such as worsening of diet, need for a feeding tube, or narrowing of the throat passage if they complied with a set of prescribed swallowing exercises called a swallow preservation protocol (SPP) during therapy. The five-year study was led by Dr. Marilene Wang, JCCC member, professor-in-residence in the department of head and neck surgery, UCLA's David Geffen School of Medicine. The study was published online ahead of print in the journal Otolaryngology - Head and Neck Surgery on August 27, 2013. Surgery and radiation (RT) have been the traditional treatments for head and neck cancer but with the advent of improved and targeted chemotherapy many types of this disease are treated with chemotherapy and radiation (chemoradiation or CRT) in the hope of preserving the tissue and structure. Despite the sparing of critical tissue, preservation does not always translate to normal, natural swallowing ability. Most patients who receive CRT have significant side effects during treatment and for a long time after recovery. Difficulty swallowing (dysphagia) is one of the most common unwanted side effects of RT and CRT, and is one of the main predictors of decreased patient quality of life after treatment. Wang's study was designed to evaluate the SPP, in which patients had swallow therapy before, during and after radiation treatment. The effectiveness [...]

Oral Cancer Foundation News Team - A2013-09-01T15:54:22-07:00September, 2013|Oral Cancer News|