Radiation exposure increases kids’ risk for developing thyroid cancer later in life

Source: www.endocrineweb.com Author: staff University of Rochester Medical Center researchers have revealed that children who are exposed to head and neck radiation during a CT scan or cancer treatment may have an increased risk of thyroid cancer in adulthood. The paper, which was published in the December issue of the journal Radiation Research, provided findings that may explain why the rates of thyroid cancer are continuing to rise, as the general public is becoming increasingly exposed to radiation through some medical procedures. "Ionizing radiation is a known carcinogen and, in fact, about 1 million CT scans are performed every year on children five years or younger," said lead author Jacob Adams. "Although CTs and other imaging tests are an important diagnostic tool, with everything comes a risk." He and his colleagues assessed a group of patients who had been treated with chest radiotherapy during infancy as a result of an enlarged thymus. Of the 1,303 individuals evaluated, 50 developed thyroid cancer, compared to only 13 controls out of 1,768 people who had not undergone radiation therapy. According to the researchers, the study supports previous evidence showing that the risk of thyroid cancer due to radiation exposure may continue for children for a median of 57.5 years.

2010-12-29T10:42:48-07:00December, 2010|Oral Cancer News|

Betel nut, oral cancer pilot study for Saipan, Guam now underway

Source: www.saipantribune.com Author: Moneth Deposa A betel nut and oral cancer pilot study will be conducted on Saipan and Guam beginning this year. The study hopes to gather baseline date to develop protocols for studying oral precancerous lesions and other health risks among betel nut users in Micronesia. University of Guam epidemiologist Dr. Yvette Paulino, co-leader in the pilot study, will work with Dr. Suzanne Murphy from the Cancer Research Center of Hawaii in the pilot study. In a presentation to members of the Commonwealth Cancer Association last week, Dr. Paulino disclosed that oral cancer is the sixth leading cancer worldwide, but ranks in the Top 3 cancers in countries where there are betel nut/areca nut chewers. Betel nut, she said, is apparently a misnomer. The nut itself is more accurately called “areca nut” and “betel” refers to the leaf that is sometimes used with the nut. “Betel quid” refers to the mixture of nut and leaf. The three-year pilot study aims to collect information on betel nut/areca nut use among 300 study participants in Guam and on Saipan and members of their families. In the course of the study, oral examinations and biopsies will be performed as needed, health risks will be measured, and associations of duration, frequency, and type of betel nut/areca nut use with oral pre-cancers and health risks will be studied. Dr. Paulino said that betel nut/areca nut is considered a human carcinogen. She revealed that betel nut chewing has been shown to be associated with [...]

U.S. cigarette brands tops in cancer causing chemicals

Source: CNN Author: Miriam Falco Smokers of U.S. brand cigarettes may get more bang for their buck in the worst way according to a small study conducted by the Centers for Disease Control and Prevention. Researchers found U.S. made cigarettes contain more cancer-causing chemicals than some cigarettes brands made elsewhere around the world. “Not all cigarettes are made alike” says Dr. Jim Pirkle, deputy director for science at the CDC’s National Center for Environmental Health. He says this is the first study to show that “U.S. cigarettes have more of the major carcinogen [TSNAs] than foreign made cigarettes." TSNAs are “tobacco-specific nitrosamines,” the major cancer-causing substance in tobacco. 126 smokers in five cities – Waterloo, Ontario; Melbourne, Victoria (Australia); London, England, Buffalo, New York, and Minneapolis, Minnesota – were recruited for this study. They were between the ages of 18 and 55 and smoked at least 10 cigarettes a day for the past year and had been brand loyal for at least three months. The cigarettes smoked by the study recruits represented some of the more popular brands for each country including: Players light and DuMaurier in Canada; Marlboro, Newport Light, Camel Light in the U.S.; Peter Jackson and Peter Stuyvesant in Australia; and Benson & Hedges and Silk Cut Purple in the United Kingdom. Scientists analyzed more than 2,000 cigarette butts to get the data they are reporting today, says Pirkle. When researchers compared cigarette brands in the U.S. to those in Canada and Australia, they found three times higher [...]

2010-06-04T13:06:10-07:00June, 2010|Oral Cancer News|

New model for oral cancer/tobacco research

Source: www.upi.com/Health_News Author: staff A carcinogen in tobacco smoke is being used in oral cancer research to provide a more relevant model to understand the disease, U.S. researchers say. Joseph Guttenplan of the the New York City College of Dentistry and Dr. Karam El-Bayoumy of the Pennsylvania State University College of Medicine say smoking is understood to be one of the leading causes of oral cancer, but research on oral cancer in has been limited to using synthetic carcinogens manufactured especially for cancer research, instead of examining the carcinogens that occur in tobacco smoke. The researchers injected low, medium and high doses of dibenzo(a,l)pyrene, a carcinogen in tobacco, into the mouths of 104 mice. After 38 weeks, one group of the mice developed excessive numbers of mutations in their oral tissue and within one year, 31 percent of a second group of mice displayed large tumors in their mouths. "As a result of this study, we now have a model that is significantly better than past models which relied on synthetic carcinogens," Guttenplan says in a statement. "We plan to use this new model in future studies to examine potential agents for cancer prevention." The findings were presented at the annual meeting of the American Association for Cancer Research in Washington.

State rules marijuana smoke is a carcinogen, may require dispensaries to post warnings

Source: www.mercurynews.com Author: April Dembosky Joints and baggies sold at California's medical marijuana dispensaries will soon carry a new warning label. Next to tags like "Purple Haze" and "White Widow" will be the advisory: Contents may cause cancer when smoked. On Friday, California added marijuana smoke to its official list of known carcinogens, joining the ranks of arsenic, asbestos and DDT. Pot brownies, lollipops and other non-inhalables are not affected by the new ruling. Scientists found the pungent smoke shares many of the same harmful properties as tobacco smoke, warranting its inclusion on the Proposition 65 warning list. The law requires the state to publish a list of chemicals known to cause cancer or reproductive toxicity, and businesses and government agencies must post warnings when they use such chemicals or sell products containing them. "Marijuana smoke is a mixture of different chemicals, and a number of those were already on the Prop. 65 list," said Allan Hirsch, chief deputy director of the state Office of Environmental Health Hazard Assessment, which made the designation. From a health perspective, pot advocates say the ruling was unsurprising, given the state's track record on documenting the harmful effects of all kinds of smoke inhalation. However, some are worried by its political implications as advocates attempt to legalize recreational use of marijuana. "I definitely have concerns about law enforcement and politicians who aren't in favor of medical marijuana or law reform, who would use this designation to further restrict access," said Allen St. Pierre, executive [...]

Using mouthwash could increase risk of cancer by nine times, claim scientists

Source: news.scotsman.com Author: Shan Ross Mouthwashes containing alcohol can cause oral cancer and should be removed from supermarket shelves, a dental health study claims. Scientists say there is now "sufficient evidence" that such mouthwashes contribute to an increased risk of the disease. The ethanol in mouthwash is thought to allow cancer-causing substances to permeate the lining of the mouth. Michael McCullough, associate professor of oral medicine at the University of Melbourne, Australia, who led the study, said: "We see people with oral cancer who have no other risk factors than the use of (mouthwash containing alcohol], so what we've done is review all the evidence. "Since this article, further evidence has come out, too. We believe there should be warnings. If it was a facial cream that had the effect of reducing acne but had a four to fivefold increased risk of skin cancer, no-one would be recommending it." Professor McCullough, chair of the Australian Dental Association's therapeutics committee, said the alcohol in mouthwashes "increases the permeability" of the mucus membrane to other carcinogens, such as nicotine. A toxic breakdown product of alcohol called acetaldehyde that may accumulate in the oral cavity when swished around the mouth is also a "known human carcinogen," he said. Top-selling mouthwashes contain as much as 26 per cent alcohol. Smoking and alcohol are well-established risk factors in causing cancer, but the use of mouthwash containing alcohol is more controversial. Prof McCullough and co- author Dr Camile Farah, director of research at the University of [...]

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