The Major Component In Tumeric Enhances The Effect Of Chemotherapy In Suppressing Head And Neck Cancers

Curcumin, the major component in the spice turmeric, when combined with the drug Cisplatin enhances the chemotherapy's suppression of head and neck cancer cell growth, researchers with UCLA's Jonsson Cancer Center have found. A naturally occurring spice widely used in South Asian and Middle Eastern cooking, Turmeric has long been known to have medicinal properties, attributed to its anti-inflammatory effects. Previous studies have shown it can suppress the growth of certain cancers, said Dr. Marilene Wang, a professor of head and neck surgery, lead author of the study and a Jonsson Cancer Center researcher. "Head and neck cancers, particularly cases diagnosed in a later stage, are terrible cancers that often require very radical surgeries and chemotherapy and radiation," Wang said. "They often don't present until late, and the structures in the head and neck are so vital that our treatments often cause disfigurement and severe loss of function. So using non-toxic curcumin as a treatment was a very appealing idea." The study, done in cells in Petri dishes and then in mouse models, appears in the October issue of the journal Molecular Cancer Therapeutics. In India, women for years have been using turmeric for medicinal purposes, as an anti-aging agent rubbed into their skin, to treat cramps during menstruation, as a poultice on the skin to promote wound healing and as an additive in cosmetics, said scientist Eri Srivatsan, an adjunct professor of surgery and a Jonsson Cancer Center researcher who, along with Wang, has been studying curcumin and its [...]

Cancer will kill 13.2 million a year by 2030: U.N.

Source: www.medscape.com Author: Reuters Health Information Cancer will kill more than 13.2 million people a year by 2030, almost double the number who died from the disease in 2008, the United Nations' cancer research agency said on Tuesday. The International Agency for Research on Cancer (IARC) also said that almost 21.4 million new cases of the disease will be diagnosed annually in 2030. Launching a new database on global incidence of cancer in 2008, the latest year for which figures are available, the IARC said the burden of cancer was shifting from wealthier to poorer nations. "Cancer is neither rare anywhere in the world, nor confined to high-resource countries," it said in a statement. In total, 7.6 million people died of cancer in 2008 and there were an estimated 12.7 million new cases diagnosed. Around 56% of new cancer cases worldwide in 2008 were in developing countries and these regions also accounted for 63% of all cancer deaths, the data showed. IARC director Christopher Wild said the data represented the most accurate available assessment of the global burden of cancer and would help international health policy makers develop their responses. The most commonly diagnosed cancers worldwide in 2008 were lung cancer, with 1.61 million cases, breast cancer, with 1.38 million, and colorectal cancers, with 1.23 million. The most common causes of cancer death were lung (1.38 million), stomach (0.74 million) and liver cancers (0.69 million) The projection for annual death rates of 13.2 million and annual diagnosis of 21.4 million [...]

HPV virus linked to some forms of breast cancer, vaccine may help

Source: www.digitaljournal.com Author: staff Scientists working out of the University of South Wales have found that a vaccine for the HPV virus could prevent some forms of breast cancer. The study proves another important link between viral infections and more complex disease. Researchers around the world are finding remarkable connections between common viral infections and the later onset of complex and life-threatening diseases. Recent stories have found viral links to prostate cancer, to Parkinson's disease, to skin cancer, to mouth cancer, and to autism and schizophrenia. Some forms of breast cancer can now be added to this list. Australian scientists working out of the University of South Wales announced an important link between the very common HPV virus and a variety of breast cancers. Their findings suggest that an HPV vaccine could prevent these cancers from presenting themselves years later. The research suggests that tens of thousands of lives could be saved every year by administering the HPV vaccine to young females. The HPV virus is the most commonly distributed sexually transmitted disease, and it is well known to have a direct causal relationship with 90 to 95 percent of all cervical cancers. It has also been linked to mouth cancers. The study linking the HPV virus to these breast cancers was published in the British Journal of Cancer and was conducted using genetic probes of cancerous breast cells. The scientists were able to confirm the presence of HPV nuclei across a variety of tissues sampled. "The finding that high [...]

2009-09-05T18:42:10-07:00September, 2009|Oral Cancer News|

Cancer researchers “play it safe” due to grant system

Source: NYTimes Author: Gina Kolata Among the recent research grants awarded by the National Cancer Institute is one for a study asking whether people who are especially responsive to good-tasting food have the most difficulty staying on adiet. Another study will assess a Web-based program that encourages families to choose more healthful foods. Many other grants involve biological research unlikely to break new ground. For example, one project asks whether a laboratory discovery involving colon cancer also applies to breast cancer. But even if it does apply, there is no treatment yet that exploits it. The cancer institute has spent $105 billion since PresidentRichard M. Nixon declared war on the disease in 1971. TheAmerican Cancer Society, the largest private financer of cancer research, has spent about $3.4 billion on research grants since 1946. Yet the fight against cancer is going slower than most had hoped, with only small changes in the death rate in the almost 40 years since it began. One major impediment, scientists agree, is the grant system itself. It has become a sort of jobs program, a way to keep research laboratories going year after year with the understanding that the focus will be on small projects unlikely to take significant steps toward curing cancer. “These grants are not silly, but they are only likely to produce incremental progress,” said Dr. Robert C. Young, chancellor at Fox Chase Cancer Center in Philadelphia and chairman of the Board of Scientific Advisors, an independent group that makes recommendations to the cancer institute. The [...]

2009-06-30T04:29:16-07:00June, 2009|Oral Cancer News|

Drink a day increases cancer risk

Source: BBC News A glass of wine each evening is enough to increase your risk of developing cancer, women are being warned. Consuming just one drink a day causes an extra 7,000 cancer cases - mostly breast cancer - in UK women each year, Cancer Research UK scientists say. The risk goes up the more you drink, whether spirits, wine or beer, the data on over a million women suggests. Overall, alcohol is to blame for about 13% of breast, liver, rectum, mouth and throat cancers, the researchers say. They estimate that about 5,000 cases of breast cancer in the UK - 11% of the 45,000 cases diagnosed each year - can be attributed to women's consumption of alcohol. The study looked specifically at women who consumed low to moderate levels of alcohol - defined as three drinks a day or fewer. Over the seven years of the study, published in the Journal of the National Cancer Institute, a quarter of the 1.3 million women reported drinking no alcohol. Of those who did drink, virtually all consumed fewer than 21 drinks per week, and an average of 10g of alcohol per day, which is equivalent to just over one unit of alcohol found in half a pint of lager, a 125ml glass of wine or a single measure of spirits. Nearly 70,000 of the middle-aged women developed cancer and a pattern emerged with alcohol consumption. One too many? Consuming one drink a day increased the risk of all types of [...]

2009-02-26T15:40:18-07:00February, 2009|Oral Cancer News|
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