Early detection, treatment helps conquer oral cancer

Source: www.newsbug.info Author: Bob Moulesong According to the Oral Cancer Foundation, almost 50,000 cases of oral cancer will be diagnosed in the U.S. in 2018. The American Cancer Society reports that 10,000 people will die from the disease this year. Half of all people diagnosed with oral cancer will be alive in five years, according to both sources. While those are disquieting statistics, Region physicians say routine checkups and early diagnosis improve the odds. Oral cancer Oral cancer includes cancers of the lips, tongue, cheeks, floor of the mouth, hard and soft palate, sinuses, saliva glands, and throat. “People we see usually come to us for a lesion or ulcer found in the mouth or throat,” says Dr. Akta Kakodkar, an ear, nose and throat specialist with Community Healthcare System. “Some of them experience no pain but notice a growth or patch of discolored tissue in their mouth, cheek or gum.” Kakodkar, who with her husband and fellow Community ENT physician, Dr. Kedar Kakodkar, treats oral cancer patients, is quick to point out that not every lesion, ulcer or mouth sore is cancer. “We see hundreds of nervous patients who have bacterial or fungal infections,” she says. “Treatment with antibiotics or antifungal medications clear up many of these lesions. There are also many white and red patches that clear up on their own.” The only way to know is a thorough examination. Types and risk factors “Most cases of oral cancer are linked to use of tobacco, alcohol and betel [...]

2019-01-04T20:02:56-07:00November, 2018|Oral Cancer News|

Patients with HPV-positive oropharynx cancer should receive chemoradiation

Source: medicalxpress.com Author: provided by European Society for Medical Oncology Patients with human papilloma virus (HPV)-positive throat cancer should receive chemoradiotherapy rather than cetuximab with radiotherapy, according to late-breaking research reported at the ESMO 2018 Congress in Munich. "Many patients have been receiving cetuximab with radiotherapy on the assumption that it was as effective as chemotherapy with radiotherapy and caused less side effects but there has been no head-to-head comparison of the two treatments," said study author Prof Hisham Mehanna, Chair, Head and Neck Surgery, Institute of Cancer and Genomic Sciences, University of Birmingham, UK. Throat cancer is rapidly becoming more common in Western countries. For example in the UK, incidence was unchanged in 1970 to 1995, then doubled in 1996 to 2006, and doubled again in 2006 to 2010.The rise has been attributed to HPV, a sexually transmitted infection. Most throat cancer was previously caused by smoking and alcohol and affected 65-70 year-old working class men. Today HPV is the main cause and patients are around 55, middle class, working, and have young children. HPV-positive throat cancer responds well to a combination of cisplatin chemotherapy and radiotherapy, and patients can survive for 30-40 years, but the treatment causes lifelong side effects including dry mouth, difficulty swallowing, and loss of taste. Patients deemed unable to tolerate chemotherapy, for example because of poor kidney function or older age, receive cetuximab, an epidermal growth factor receptor (EGFR) inhibitor, and radiotherapy. This study compared side effects and survival with the two treatments in [...]

New risk factor for mouth cancer uncovered

Source: www.medicalnewstoday.com Author: Tim Newman, fact checked by Paula Field In some regions, mouth cancer incidence has risen. A recent study investigates a new risk factor for mouth cancer. In certain parts of the world, over the past couple of decades, mouth cancer rates have soared. For instance, in the United Kingdom, rates of mouth cancer have increased by 68 percent. They rose from eight cases per 100,0000 in 1992–1995 to 13 cases per 100,000 in 2012–2014. In the United States, mouth cancer and mortality rates have declined overall. However, when examined at a state level, the data reveal a more complex picture. For instance, mouth cancer deaths have risen significantly in Nevada, North Carolina, Iowa, Ohio, Maine, Idaho, North Dakota, and Wyoming. Some known risk factors for mouth cancer include smoking tobacco, drinking alcohol, human papillomavirus (HPV), and chewing betel quid, which is a mix of natural ingredients wrapped in a betel leaf that is popular in some parts of Southeast Asia. In India, mouth cancers are the most common cause of cancer-related deaths in men aged 30–69 years old. Scientists think that chewing betel quid could be responsible for many of these deaths. New risk factor for mouth cancer Although scientists have confirmed some risk factors, there is still much to learn about how and why mouth cancer affects certain individuals and not others. Recently, scientists set out to investigate another potential risk factor: air pollution. The researchers, funded by the Ministry of Science and Technology in Taiwan, [...]

Head and neck cancer: An overview of head and neck cancer

Source: www.curetoday.com Author: staff Meryl Kaufman, M.Ed., CCC-SLP, BRS-S, and Itzhak Brook, M.D., M.Sc., board members of the Head and Neck Cancer Alliance, discuss the prevalence of cancers of the head and neck, emphasizing the potential risk factors and importance of prevention. Transcript: Meryl Kaufman, M.Ed., CCC-SLP, BRS-S: Welcome to this CURE Connections® program titled “Head and Neck Cancer: Through the Eyes of a Patient.” I’m Meryl Kaufman, a certified speech-language pathologist and founder of Georgia Speech and Swallowing LLC. I am joined today by Dr. Itzhak Brook, a professor of pediatrics and medicine at Georgetown University School of Medicine, who was diagnosed with throat cancer in 2006. Together we will discuss the prevalence of head and neck cancer, what unique challenges patients may face and how one can adjust to life after receiving treatment for their disease. Dr. Brook and I also serve as board members on the Head and Cancer Alliance. Dr. Brook, let’s talk about head and neck cancer in general. What’s the difference between head and neck cancer associated with the traditional risk factors, such as smoking and drinking, and HPV-related head and neck cancers? Itzhak Brook, M.D., M.Sc.: The traditional head and neck cancer is related to smoking and alcohol consumption. It’s usually associated with a high rate of laryngeal cancer. And HPV-related cancer is a relatively new arrival on the scene of head and neck cancer, and it’s associated with a condition of infection by a venereal disease. The virus HPV is usually associated with [...]

2018-09-04T13:04:43-07:00September, 2018|Oral Cancer News|

With oral cancer on the rise, dentists can play an important role

Source: http://exclusive.multibriefs.com Author: Tammy Adams Today's dental professionals routinely see and deal with many issues and conditions that were not so common just a few short decades ago. For example, there has been a marked increase in the incidence of oral cancer in the United States, sparking the need for regular oral cancer screening as part of a preventive dental checkup. This additional screening is now routinely performed in many dental practices across the nation. The American Cancer Society estimates that around 50,000 Americans are infected with oral cancer each year. In past generations, oral cancer was mostly linked to smoking, alcohol use or a combination of the two. But even as smoking rates have fallen, oral cancer rates have risen (especially in men), and researchers have concluded that this is likely caused by the human papillomavirus (HPV), a sexually transmitted disease. Early diagnosis makes a difference Oral cancer is often only discovered when the cancer has metastasized to another location, most commonly the lymph nodes of the neck. Prognosis at this stage of discovery is significantly worse than when it is caught in a localized intraoral area. According to the Oral Cancer Foundation, the best way to screen for HPV-related oral and oropharyngeal cancer is through a visual and tactile exam given by a medical or dental professional, who will also perform an oral history taking to ask about signs and symptoms that cover things that are not visible. Most of the symptoms of a developing HPV-positive infection are [...]

Be your own advocate

Source: www.wvnews.com Author: Mary McKinley The importance of dental care goes beyond cavities — it’s also about preventing cancer. The week of April 8 is National Oral, Head and Neck Cancer Awareness Week, and your dentist or dental hygienist may be your first line of defense against oral cancer. More than 50,000 Americans are expected to be diagnosed with oral or oropharyngeal cancer (cancer of the back of the throat, including the base of the tongue and the tonsils) in 2018, and 350 will be diagnosed in West Virginia alone. Routine dental exams can detect cancer or pre-cancers during the early stages. If you notice a persistent sore or pain, swelling or changes in your mouth, or red or white patches on the gums, tongue, tonsils or lining of the mouth, visit a doctor or dentist so they can examine your mouth more closely. Some people diagnosed with oral cancer have no risk factors, so it’s important for everyone to keep those dental appointments. If you use tobacco, drink alcohol in excess, or have the human papillomavirus (HPV), you have an increased risk for oral cancer. Oral cancer is more common in older adults, particularly men, but oropharyngeal cancer is on the rise in middle-aged, nonsmoking white men between the ages of 35 and 55. The majority of these types of cancer cases are caused by HPV. Take charge of your health and reduce your risk of oral cancer. If you smoke or chew tobacco, quit now (it’s never too [...]

Management strategies for oral potentially malignant disorders

Source: www.medscape.com Author: Joel M. Laudenbach, DMD Oral potentially malignant disorders (OPMDs) include oral leukoplakia (OL), oral erythroplakia, oral submucous fibrosis, oral lichen planus, proliferative verrucous leukoplakia, and actinic keratosis. Once an OPMD has been clinically diagnosed, execution of management strategy is critical. When formulating the strategy, healthcare providers should consider histopathology, lesion characteristics (ie, surface texture, unifocal, multifocal), lesion location in the mouth (ie, tongue, floor of mouth), patient risk factor assessment, and a detailed medical/cancer history. In this newly published article, Nadeau and Kerr[1] detail various parameters surrounding evaluation and management of OPMDs. The authors make it clear that OPMDs are challenging, each with their own nuances regarding risk for malignant transformation. For example, when OL is unifocal, nonhomogeneous, nodular, or verrucous, there is a much higher chance of the OL becoming dysplastic (12.63-fold) or demonstrating a focus of carcinoma (8.9-fold) when compared with homogeneous types of OLs.[1] Provider knowledge of these variables is critical when counseling patients about their diagnosis and management options and when selecting interventions along with follow-up care. Although progression to malignancy is difficult to predict with OPMDs, clinicians can account for multiple risk factors such as smoking/alcohol status, high-risk location in the oral cavity, and size of lesion (>200 mm2) to help formulate a tailored management plan for each patient. Consultation with an oral pathologist to discuss the histologic appearance in the context of specific patient history and lesion characteristics can provide additional perspective and/or recommendations. Modifiable oral cavity cancer risks related to [...]

HPV is causing an oral cancer epidemic in men by outwitting natural defenses

Source: www.philly.com Author: Marie McCullough, staff writer Five years ago, when actor Michael Douglas candidly revealed that his throat cancer was linked to having oral sex, two things happened. He made headlines that mortified his family. And he helped publicize the fact that a pervasive, sexually transmitted virus called HPV was unleashing an epidemic of oral cancer among men. Since then, scientists have made headway in figuring out why HPV, the human papillomavirus, has this glaring gender bias. Men are four times more likely than women to be diagnosed with oral cancer, a hard-to-detect, hard-to-treat disease that has overtaken cervical cancer as the most common HPV-related malignancy in the United States. To be sure, changes in sexual norms over the last few generations have played a role in this alarming trend. But research increasingly shows the real problem is something men have practically no control over: their immune response. Compared with women, men are more likely to get infected with HPV — including “high-risk” cancer-causing strains. They also are less able to wipe out infection on their own, and more likely to get reinfected. The reasons are unclear. “There is good evidence that men acquire oral infections more readily than women, even if they have similar sex practices,” said Ashish A. Deshmukh, a University of Florida HPV researcher. “And more than the acquisition, it’s the persistence of the virus. The clearance rate is not that fast in men.” Michael Becker of Yardley has stepped up as the face of this [...]

Alcohol and cancer – facts and health risks

Source: mesothelioma.net Author: staff Alcohol and Cancer – Facts and Health Risks While there are proven health benefits of drinking alcohol in moderation, and some specific benefits due to the natural compounds found in red wine, drinking is not always good for your health. Drinking regularly and to excess can have some serious and negative impacts on health and may even be linked to an increased risk for mesothelioma or other cancers. Drinking alcohol in moderation during cancer treatment may be fine for some patients, but generally it should be avoided. It may aggravate side effects and studies are also investigating whether or not alcohol can increase the risk of a cancer recurrence. If you are going through treatment for mesothelioma or another type of cancer, talk to your medical team before indulging in a drink or two. Alcohol Consumption is a Risk Factor for Cancer Many studies have found and confirmed, over and over again, that drinking alcohol is a risk factor for developing cancer generally and for specific types of cancers. Specifically, drinking has been linked with throat and mouth cancers, esophageal cancer, liver cancer, colon cancer, breast cancer, stomach cancer, and pancreatic cancer. The more alcohol consumed, the greater the risk. According to research data, approximately 3.5 percent of cancer deaths are related to alcohol consumption. Some of the specific facts about drinking and cancer from research include: People who drink three to four alcoholic beverages per day have a two to three times increased risk of [...]

2017-12-15T08:00:31-07:00December, 2017|Oral Cancer News|

Top cancer doctors have some advice about alcohol

Source: www.newser.com Author: staff Name things that increase your risk of cancer. Cigarettes and tanning beds might quickly come to mind. But how about alcohol? A recent survey of 4,016 adults by the American Society of Clinical Oncology found that only 30% knew alcohol is a risk factor for cancer, reports the New York Times. ASCO, which includes many leading cancer doctors, had yet to voice its own thoughts on the topic. That changed this month, with the Nov. 7 publication of a statement in the Journal of Clinical Oncology that begins by calling the link between the two "often underappreciated" and noting that "addressing high-risk alcohol use is one strategy to reduce the burden of cancer." "Despite the evidence of a strong link between alcohol drinking and certain cancers, ASCO has not previously addressed the topic of alcohol and cancer." In the statement they cite outside research they've found to be sound, like an estimate that 5.8% of global cancer deaths in 2012 were attributable to alcohol, and evidence that drinking can increase the risk of mouth, throat, voice box, liver, breast, esophageal, and colorectal cancers. So what's the upshot? It's not "Don't drink," lead statement author Dr. Noelle LoConte tells the Times. "It's different than tobacco where we say, 'Never smoke. Don't start.' This is a little more subtle"—drink less, essentially. (Though the statement does contain the line, "People who do not currently drink alcohol should not start for any reason.") So what's Wine Spectator's response? [...]

2017-11-21T07:39:50-07:00November, 2017|Oral Cancer News|
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