Link between coffee and dental care – lower your oral cancer risk

Source: blogjam.eu Author: Jenny L McCoy Studies have already shown that coffee may benefit dental care by reducing the risk of developing cavities. Now there’s even more good news for java junkies. Researchers have discovered that drinking a lot of coffee actually lowers your risk of mouth and throat cancer. According to the findings featured in WebMD, people who drink more than four servings of coffee daily have nearly a 40% lower chance of contracting mouth or throat cancer when compared to people who don’t drink coffee. For those who drank less than five cups of coffee daily, the level of protection fell to still significant 4% lower odds for contracting mouth and throat cancer for each cup of coffee consumed each day. Protection for oral and pharyngeal cancer was evident, but protection against cancer of the larynx was not. Coffee’s protective effect was shown to remain intact even for drinkers and smokers, despite the fact that tobacco and alcohol consumption are linked to head and neck cancers. Additionally, the protection effect didn’t demonstrate a boost by consuming fruits and vegetables, which are also known to protect against head and neck cancers. The researchers at the University of Milan reached these findings when they analyzed nine studies comparing 5,139 people with head and neck cancer to 9,028 people without cancer. So, which ingredient in coffee is responsible for reducing the risk of oral cancer? The study dismissed caffeine as a likely possibility since drinking tea, even in mass quantities, was [...]

Curry spice ‘kills cancer cells’

Source: news.bbc.co.uk An extract found in the bright yellow curry spice turmeric can kill off cancer cells, scientists have shown. The chemical - curcumin - has long been thought to have healing powers and is already being tested as a treatment for arthritis and even dementia. Now tests by a team at the Cork Cancer Research Centre show it can destroy gullet cancer cells in the lab. Cancer experts said the findings in the British Journal of Cancer could help doctors find new treatments. Dr Sharon McKenna and her team found that curcumin started to kill cancer cells within 24 hours. 'Natural' remedy The cells also began to digest themselves, after the curcumin triggered lethal cell death signals. Dr McKenna said: "Scientists have known for a long time that natural compounds have the potential to treat faulty cells that have become cancerous and we suspected that curcumin might have therapeutic value." Dr Lesley Walker, director of cancer information at Cancer Research UK, said: "This is interesting research which opens up the possibility that natural chemicals found in turmeric could be developed into new treatments for oesophageal cancer. "Rates of oesophageal cancer have gone up by more than a half since the 70s and this is thought to be linked to rising rates of obesity, alcohol intake and reflux disease so finding ways to prevent this disease is important too." Each year around 7,800 people are diagnosed with oesophageal cancer in the UK. It is the sixth most common [...]

Rising number of college students smoking hookah raises concern for oral cancer

Source: eon.businesswire.com Hookah smoking, where specially made flavored tobacco is heated, passed through water and drawn through a rubber pipe, has been around for centuries. According to a recent study conducted at the University of Pittsburgh School of Medicine, however, these days hookah use is on the rise among college-age Americans. In fact, one in three college students has smoked a hookah at some point. In response to this alarming trend, the largest ear, nose, throat, allergy and audiology practice in the tri-state area, ENT and Allergy Associates, LLP (ENTA), which is highly involved with the American Cancer Society’s Great American Smokeout, is calling for increased public awareness about the risks associated with hookah smoking. ENTA stresses the importance of quitting this unhealthy habit and provides tips on what young people can do to help decrease their chances of developing oral cancer. “Young people need to be made aware of the negative impact of hookah smoking on their health, including the increased risk for developing oral cancer,” explains Michael Bergstein, M.D., FACS, of the ENTA office in Sleepy Hollow, N.Y. “A typical hookah session can last up to one hour, with smokers taking long, deep breaths, so that the smoke inhaled can equal 100 cigarettes or more, according to a 2005 study by the World Health Organization. Therefore, it is critical that hookah smokers stop immediately and practice preventive measures against oral cancer.” Individuals should routinely perform simple oral self-exams of their mouth in order to help detect early changes [...]

Facing the Facts: HPV-Associated Head and Neck Cancers Get a Second Look

Source: CureToday.com HPV causes surge in oral cancer rates. Kevin Pruyne knew he didn’t fit the stereotype of a hard drinker or heavy smoker who one day develops an oral cancer. The 52-year-old mechanic had been working a three-week stint in a remote section of northern Alaska, repairing trucks on an oil field, when he noticed a hard lump beneath his jaw while shaving. For nearly three months, as Pruyne was prescribed antibiotics for a possible infection and then later shuttled between physician specialists, he kept hearing the same thing: the lump could not be cancer. Pruyne only occasionally consumed alcohol and had never smoked. His wife, Kathy, began researching her husband’s symptoms, which included repetitive throat clearing, a nagging sensation that something was lodged in his throat and ringing in his ears. And the lump, which looked like the top half of an egg, felt solid to the touch. This wasn’t some inflamed lymph node from a lingering head cold, Kathy Pruyne says. “He had every symptom [of cancer], but nobody would listen to me.”   Kevin Pruyne, with his wife, Kathy, is hopeful his HPV-positive oral cancer will be cured. Photo by Rick Bacmanski. Pruyne received a diagnosis of stage 4 oral cancer, which started with a tumor at the base of his tongue. He had already begun chemotherapy when he learned that researchers had discovered an association between the human papillomavirus (HPV) and increasing rates of oropharyngeal cancers. He asked that his tissue be tested; the results came [...]

2012-06-20T12:05:38-07:00June, 2012|Oral Cancer News|

Vitamin B veggies cut risk of mouth cancer

Source: www.dentistry.co.uk Author: staff Women who consume high volumes of folic acid found in vitamin B from vegetables and some fruits are less likely to suffer from mouth cancer. A sample of 87,000 nurses were followed for 30 years from 1976 by researchers from the Columbia University Medical Centre and Harvard School of Public Health. Women who drank a high volume of alcohol and had low folic acid intake were three times more likely to develop mouth cancer than those who drank high volumes of alcohol but had high volumes of folic acid in their diet. Alcohol is one of the major risk factors for mouth cancer and those who drink to excess are four times more likely to be diagnosed. This is the first time that folic acid intake has been shown to affect the risk of the disease. Alcohol leads to a reduction in folic acid metabolism by creating acetaldehyde which leads to a reduction of folic acid in the body. Chief executive of the British Dental Health Foundation, Dr Nigel Carter, said: 'Rates of mouth cancer in women have been increasing for many years as a result of changed social habits with more women smoking and drinking. 'This new research could offer a method to reduce this by looking at the folic acid intake and increasing fruit and vegetables containing folic acid in the diet. “In the past studies have tended to focus on males, as they are twice as likely to suffer from the disease. While [...]

Actor Michael Douglas Partners With Oral Cancer Foundation For Early Detection PSA Campaign

LOS ANGELES, May 14, 2012 /PRNewswire-USNewswire/ -- Actor and producer Michael Douglas has donated his time to help create a television public service announcement (PSA) on behalf of the Oral Cancer Foundation (OCF), a non-profit organization dedicated to helping those affected by the disease. The PSA will support the Foundation's efforts to educate the public about the need for annual screenings to catch oral cancers in their early, most survivable stages. The public service announcement will begin airing in June, and will continue to air nationwide through summer and autumn. Approximately 40,000 people in the US will be newly diagnosed with oral cancer in 2012. This includes those cancers that occur in the mouth itself, in the very back of the mouth known as the oropharynx, and on the exterior lip of the mouth. There are two distinct pathways by which most people come to oral cancer. One is through the use of tobacco and alcohol, and the other is through exposure to the HPV-16 virus (human papilloma virus version 16), a newly identified etiology, and the same virus which is responsible for the vast majority of cervical cancers in women. While oral cancer has historically been linked to tobacco and alcohol use, this is not simply a smoker's disease any longer. New data shows that the fastest-growing segment of newly diagnosed cases is now young, non-smokers. Most startling, is the fact that while many other cancers have been in decline in recent years, the occurrence of oral / oropharyngeal [...]

2012-05-14T19:59:49-07:00May, 2012|OCF In The News, Oral Cancer News|

New method of predicting the spread of throat cancer to other body parts found

Source: starglobaltribune.com Author: staff Independent of other factors, such as smoking history and HPV status, matted lymph nodes appear to signal increased chance of oropharyngeal cancer spreading to other parts of the body. Researchers at the University of Michigan Health System have found a new indicator that may predict which patients with a common type of throat cancer are most likely have the cancer spread to other parts of their bodies. Patients with oropharyngeal squamous cell carcinoma who had “matted” lymph nodes – nodes that are connected together – had a 69 percent survival rate over three years, compared to 94 percent for patients without matted nodes, according to a study published online ahead of print publication in Head & Neck. The oropharynx is an area that includes the back of the tongue, soft palate, throat and tonsils. “The spread of cancer throughout the body accounts for about 45 percent of the deaths from oropharyngeal carcinoma,” says the study’s senior author, Douglas B. Chepeha, M.D., M.S.P.H., an associate professor of otolaryngology head and neck surgery at the U-M Medical School. “Our findings may help doctors identify patients who are at higher risk for having their cancer metastasize and who would benefit from additional systemic therapy. Conversely, some patients without matted nodes may benefit from a reduction of the current standard treatment, which would cut down on uncomfortable side effects.” Notably, the findings indicate an increased risk independent of other established prognostic factors, such as the patient’s history of smoking or [...]

Ireland: mouth cancer awareness day yields results

Source: http://www.dentistryiq.com/ Author: staff Dentists are emphasizing the importance of early detection with mouth cancer, after 12 cases of the potentially deadly cancer were discovered on Mouth Cancer Awareness Day and one of these was discovered in Waterford. The Irish Dental Association estimates that 10,000 people availed of free mouth cancer examinations carried out by participating dentists countrywide on September 21 of last year. As well as the confirmed cases, 286 people were advised to attend their GP for other related problems. Mouth Cancer Awareness Day was set up by a group of mouth, head and neck cancer survivors in September 2010. It is now a joint initiative by the Irish Dental Association, Irish Cancer Society, Dublin Dental University Hospital, Cork Dental University Hospital, the Dental Health Foundation and Mouth, Head and Neck Cancer Awareness Ireland. The President of the IDA, Conor McAlister said the fact twelve cancers were discovered in one day showed the importance of early detection and the need for everyone to have a regular examination. He said, "Three hundred cases of mouth cancer are detected here each year with 100 deaths and this type of cancer actually kills more Irish people than cervical cancer or skin melanoma. "According to the National Cancer Register in Ireland, roughly 50% of all mouth cancers are diagnosed at an advanced stage. Hopefully the fact these 12 cases have been caught at an earlier stage means the impact on quality of life will be reduced." He added, "This year we saw [...]

Prognostic Significance of HPV Status in Oropharyngeal Cancer

OncologySTAT Editorial Team Dr. Maura Gillison is Professor of Medicine, Epidemiology, and Otolaryngology at Ohio State University in Columbus. OncologySTAT: The results of the Radiation Therapy Oncology Group (RTOG) 0129 trial showed that the human papillomavirus (HPV) is an independent prognostic factor in oropharyngeal cancer. Could you tell us about the rationale for this study? Dr. Gillison: Over the last 10 years, our research has shown that cancers of the oropharynx are actually 2 completely different diseases that can look quite similar. One subset is caused HPV infection, and the other is more closely associated with long-term use of alcohol and tobacco. Initial studies suggested that the presence of HPV in a patient’s tumor had prognostic significance, but study limitations made that conclusion dubious. We set out to determine whether or not HPV was indeed an independent prognostic factor in head and neck cancer. To show whether there was a direct relationship between HPV infection and head and neck cancer, we needed to prospectively study a uniformly treated and uniformly staged patient population. Thus, we used the study population from the trial conducted by the RTOG. We divided the patients into 2 groups—those whose tumors were caused by HPV and those whose tumors were not—and we compared survival outcomes for the 2 groups. The results showed that HPV status was the single most important predictor of patient outcome, even more so than disease stage and other well-known prognostic factors such as performance status and presence of anemia. In fact, after [...]

2012-04-18T10:16:03-07:00April, 2012|Oral Cancer News|

Oral cancer and cultural factors in Asia

Source: findarticles.com Authors: Sherry L Priebe, Jolanta Aleksejuniene, Shafik Dharamsi, Christopher Zed Abstract: Oral cancer is on the rise worldwide, with over 200,000 cases diagnosed yearly. The predisposing social and cultural habits related to this disease acquired in resource-poor countries in Southeast Asia remain prevalent among its users following migration to other and better resourced countries. As a result, countries that once rarely experienced high levels of oral cancer will likely see an increased incidence of this disease. Therefore, oral health professionals need to be aware of the cultural risk factors and the resulting oral health effects in order to respond effectively to the increasing incidence of oral cancer. The objective of this overview is to inform what is known about populations from resource poor countries in Asia in regards to oral cancer and its related cultural factors. Introduction: The social and cultural habits that may predispose people to oral cancer are common in resource-poor countries in Southeast Asia, and remain prevalent among its users following migration to other and better resourced countries. As a result, countries that once rarely experienced high levels of oral cancer will likely see a considerable increase of this disease. It has been suggested that following migration from these countries to North America, the habit has remained prevalent among this ethnic group. (1) Increasing the level of awareness among oral health professionals about oral cancer and its related cultural risk factors, as well as developing better early diagnosis are of key importance in addressing morbidity [...]

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