Leech Therapy Continues to Show Promise in Salvaging Free Tissue Flaps
8/10/2004 NEW YORK By Anthony J. Brown, MD Reuters Health New findings from a long-term study provide further evidence that leeches can be used to save head and neck free tissue flaps typically considered unsalvageable. In the study, the flaps were saved in all 15 patients treated with leeches. Although this therapy is associated with considerable blood loss and other problems, the chance to avoid a second reconstructive surgery is probably worth the risk, lead author Dr. Douglas B. Chepeha told Reuters Health. "The speech and swallowing results, as well as the cosmetic results of a second flap operation are never as good as the first."In a report published in 2002, Dr. Chepeha and colleagues, from the University of Michigan in Ann Arbor, described the outcomes of eight patients who were treated with leech therapy at their institution between 1995 and 2000. The flaps were saved in all cases, although transfusion requirements were often high and ICU psychosis and prerenal azotemia were common problems. In a study update, presented Monday at the 6th International Conference on Head and Neck Cancer in Washington, DC, Dr. Chepeha described the outcomes of the original cohort as well as seven additional patients who were treated after 2000. All of the subjects had free tissue flaps that developed venous obstruction that could not be corrected with surgery or thrombolytic therapy. Patients undergoing leech therapy were admitted to the ICU where three leeches are placed every hour until inosculation occurs. During the ICU stay, antithrombotic therapy [...]