Oral Cancer Foundation praised for its social media efforts

Source: The Oral Cancer Foundation Author: John Pohl Social Media Guru Mashable.com Cites Organizations Using Social Media for Public Good The Oral Cancer Foundation was recently praised by a leading Internet media website in an article discussing non-profit organizations that are effectively using Internet based social media for the public good.  Mashable, the world’s largest site focused exclusively on Web 2.0 and social media such as blogs, Facebook, YouTube and Twitter, touted the online efforts of several organizations in a recent story entitled, 5 Unique Social Good “Finds”.  Other organizations cited included The National Suicide Prevention Hotline and the ASPCA. Founded in July 2005, Mashable is the most prolific source for information and reviews of new websites and services, publishes breaking news on new web developments, and provides social media resources and guides. Mashable's audience includes early adopters and influencers, social media enthusiasts, entrepreneurs, large and small corporations, marketing, PR and advertising agencies, Web 2.0 aficionados, and technology journalists. “We are flattered that our social media efforts have generated the attention and kind words of such a leading edge organization,” said Brian Hill, Founder and Executive Director of the Oral Cancer Foundation.  “We dedicate a great deal of time and focus to social media, which we believe allows us to connect with younger members of our audience in a way that is richer, more meaningful, and more relevant than we can achieve using more traditional media. This is particularly important to us, as individuals impacted by oral cancers have been [...]

2009-06-30T16:00:34-07:00June, 2009|OCF In The News|

Blueberries: cancer-fighting flowers in disguise

Source: www.examiner.com Author: Julie LeBlanc                                                         I can’t say I’ve been one for gardening. Or just liking plants, in general, for that matter. I’m the person that killed two rose bushes within two weeks while living in the school dormitories last year. It’s things like this that make you contemplate becoming a super-villain. Even I was amazed to find out that blueberries are not, in fact, berries at all. They’re not even fruit. Reference.com claims they are “epigynous fruits” which, aside from having a name that could tongue-tie Mr. Ed, means that they are actually flowers. Tiny, blue, delicious flowers that go fabulously with vanilla ice cream. Instead of parts like the stamen and petals falling off when the bud is ready to ripen, these organs stay attached and actually form alongside the plant ovary to create these little “false fruits.” Other veggies in this genre of plants include cucumbers, melons, bananas and figs. Sneaky little buggers. “The health properties of blueberries” or “Why you need another reason to eat these for dessert”: Containing only about 40 calories in ½ a cup, blueberries have ascended to the superfood pantheon which includes, among other things, açai berries, red wine and plums. Like their cancer-fighting counterparts, blueberries contain high levels of anthocyanins and antioxidants, two phytonutrients which amp up the body’s immune system and to detoxify harmful chemicals. Some species even contain reservatrol, another phytonutrient that aids in fighting cancer and Alzheimer’s.  Red grapes and red wines are well-known for containing high [...]

Cancer researchers “play it safe” due to grant system

Source: NYTimes Author: Gina Kolata Among the recent research grants awarded by the National Cancer Institute is one for a study asking whether people who are especially responsive to good-tasting food have the most difficulty staying on adiet. Another study will assess a Web-based program that encourages families to choose more healthful foods. Many other grants involve biological research unlikely to break new ground. For example, one project asks whether a laboratory discovery involving colon cancer also applies to breast cancer. But even if it does apply, there is no treatment yet that exploits it. The cancer institute has spent $105 billion since PresidentRichard M. Nixon declared war on the disease in 1971. TheAmerican Cancer Society, the largest private financer of cancer research, has spent about $3.4 billion on research grants since 1946. Yet the fight against cancer is going slower than most had hoped, with only small changes in the death rate in the almost 40 years since it began. One major impediment, scientists agree, is the grant system itself. It has become a sort of jobs program, a way to keep research laboratories going year after year with the understanding that the focus will be on small projects unlikely to take significant steps toward curing cancer. “These grants are not silly, but they are only likely to produce incremental progress,” said Dr. Robert C. Young, chancellor at Fox Chase Cancer Center in Philadelphia and chairman of the Board of Scientific Advisors, an independent group that makes recommendations to the cancer institute. The [...]

2009-06-30T04:29:16-07:00June, 2009|Oral Cancer News|

New cancer treatment shows promise in testing

Source: nytimes.com Author: Nicholas Wade A new method of attacking cancer cells, developed by researchers in Australia, has proved surprisingly effective in animal tests. The method is intended to sidestep two major drawbacks of standard chemotherapy: the treatment’s lack of specificity and the fact that cancer cells often develop resistance. In one striking use of the method, reported online Sunday in Nature Biotechnology, mice were implanted with a human uterine tumor that was highly aggressive and resistant to many drugs. All of the treated animals were free of tumor cells after 70 days of treatment; the untreated mice were dead after a month. The lead researchers, Jennifer A. MacDiarmid and Himanshu Brahmbhatt, say their company, EnGeneIC of suburban Sydney, has achieved a similar outcome in dogs with advanced brain cancer. “We have been treating more than 20 dogs and have spectacular results,” Dr. Brahmbhatt said. “Pretty much every dog has responded and some are in remission.” These experiments have not yet been published. Cancer experts who were not involved with the research say that the new method is of great interest, but that many treatments that work well in laboratory mice turn out to be ineffective in patients. Bert Vogelstein, a leading cancer researcher at Johns Hopkins University, called the method “a creative and promising line of research,” but noted the general odds against success. “Unfortunately our track record shows that far less than 1 percent of our promising approaches actually make the grade in patients,” he said. The EnGeneIC [...]

Oral health suffers in down economy

Source: www.myjournalcourier.com Author: Katie Anderson As layoffs and furlough days continue to eat away at pocket books, local dentists say they’ve noticed a decrease in the area’s appetite for oral health care. Dental health care experts are concerned. “I think a lot of preventative care has become affected by people’s economic situations,” said Randall Lawson, a doctor of dental surgery and owner of College Avenue Dental in Jacksonville. “I have two hygienists that do preventive care, cleanings, et cetera, and they have seemed to become less busy as of late.” He said although the summer time is busier due to children being out of school, his office has seen more cancellations than usual. William Weller, a doctor of dental surgery with an office on West Lafayette Avenue, has seen a similar trend at his practice. “Whenever we have a downturn or anything like this there are several things that happen,” Dr. Weller said. “Probably the most significant is people looking for ways to cut corners — looking to delay or postpone their six-month checkups. It’s kind of unfortunate because yes, they’ll save 100 bucks on a checkup but they’ll pay later.” Dr. Weller said the people he and his fellow dentists treat in the area, for the most part, “are really honest people.” “If they don’t have the money they don’t want to come in and incur a debt,” he explained. “Which is laudable to some degree, but something that we worry about.” They worry for many reasons. One, most [...]

Vanderbilt-Ingram Cancer Center’s research efforts highlighted at annual cancer conference

Source: www.mc.vanderbilt.edu Author: Dagny Stuart A new drug which targets a genetic mutation found in more than 50 percent of melanoma cases, 10 percent to 15 percent of colorectal tumors and 8 percent of other solid tumors, caused tumor shrinkage and extended progression-free survival among patients during a recent Phase 1 clinical trial. Igor Puzanov, M.D., assistant professor of Medicine, and Jeffrey Sosman, M.D., Ingram Professor of Cancer Research, led Vanderbilt-Ingram Cancer Center's participation in the multi-center study. Puzanov delivered the initial findings during a poster session at the recent American Society of Clinical Oncology (ASCO) conference in Orlando, Fla. Puzanov and Sosman were among nearly a dozen VICC cancer investigators who were invited to give oral or poster presentations on their latest research findings during the ASCO conference. PLX4032 is a novel, highly selective drug that targets the BRAFV600E cancer-causing genetic mutation. In addition to tumor shrinkage and delay in tumor progression, some patients reported clinical improvement in symptoms. “The BRAFV600E mutation activates the MAP kinase signaling pathway, causing cells to proliferate. One of the hallmarks of cancer is this uncontrolled, unregulated cell proliferation,” said Puzanov. “The new drug is a very selective inhibitor which appears to target only this mutation, and it blocks the unregulated cell growth and causes cell death.” In patients without the mutation, no clinical response to treatment was observed and progression-free survival was less than two months, consistent with historical data. “This is personalized medicine at its best,” said Sosman. “If continued trials confirm [...]

Zila enters into merger agreement with Tolmar

Source: www.earthtimes.org Author: press release Zila, Inc. today announced that it has entered into a definitive merger agreement with Tolmar Holding, Inc., a privately held, pharmaceutical research, development, manufacturing and commercial operations company. Under terms of the agreement, Tolmar will acquire all of the outstanding shares of Zila for a cash purchase price of $0.38 per share, representing an approximate premium of 18% over the closing price of Zila’s shares on June 24, 2009. Total consideration paid by Tolmar includes the purchase of Zila’s existing $12 million senior secured convertible debt at a discount. The proposed merger transaction is subject to customary closing conditions, including approval by Zila’s stockholders, but is not subject to any financing contingency. David Bethune, Zila’s chairman and CEO, stated, “We are fortunate to have entered into this merger agreement with Tolmar, given Zila’s current financial condition and our inability to access the financial markets. The Board of Directors conducted a substantial and exhaustive review of Zila’s available alternatives, before concluding that this transaction was fair to and in the best interest of the company and its stockholders. I am gratified that we have found a way to both satisfy our debt obligations and provide value for our shareholders. This merger will provide the resources and platform for Zila’s dedicated employees to realize the true worldwide potential of Zila’s oral cancer screening and periodontal products." About Zila, Inc. Zila, Inc., headquartered in Scottsdale, Arizona, is a diagnostic company dedicated to the prevention, detection and treatment of [...]

Detecting subtle changes in cancer cells with nanofluidic biopsy

Source: www.azonano.com Author: staff By taking two standard laboratory techniques—capillary electrophoresis and antibody-based protein detection—and shrinking them to the nanoscale, researchers at the Stanford University School of Medicine have created a new method for detecting miniscule changes in the levels of proteins associated with cancer. In a study published in the journal Nature Medicine, the investigators used their new device to analyze whether individual cancer-associated proteins were present in the tiny samples and even whether modifications of the proteins varied in response to cancer treatments. Although the study focuses on blood cancers, the hope is that the technique also might provide a faster, less invasive way to track solid tumors. “Currently, we don’t know what’s going on in a patient’s tumor cells when a treatment is given,” said Alice C. Fan, M.D., who along with Dean W. Felsher, M.D., headed the team that developed this nanofluidic proteomic immunoassay (NIA) system. “The standard way we measure whether a treatment is working is to wait several weeks to see if the tumor mass shrinks. It would be a leap forward if we could detect what is happening at a cellular level.” Dr. Felsher, who is a member of the Center for Cancer Nanotechnology Excellence Focused on Therapy Response based at Stanford University, added, “This technology allows us to analyze cancer-associated proteins on a very small scale. “Not only can we detect picogram levels—one-trillionth of a gram—of protein, but we also can see very subtle changes in the ways the protein is modified.” [...]

Mark Karan’s track “Walk Through the Fire” -proceeds to benefit OCF

Source: Marinij.com Author: Paul Liberatore Singer-guitarist Mark Karan wrote the title track to this heartfelt solo album while he was in a hospital bed, steeling himself for a battle against throat cancer. After chemotherapy and radiation, Karan, one of rock's most respected sidemen, has been pronounced cancer-free and has returned to his lead guitar slot in Bob Weir's band RatDog. The song "Walk Through the Fire" is about personal resolve, humility, acceptance, courage and lessons learned in his brush with the life-threatening disease. Karan, who lives in Fairfax, manages this without being preachy or mawkish, showing maturity and strength in dealing with what was an intensely emotional experience. Profits from the track will go to the Oral Cancer Foundation. After Jerry Garcia's death, Karan was chosen to share his lead guitar slot with Steve Kimock in the post-Grateful Dead band the Other Ones, playing with that group for its two tours. When Weir, the Dead's rhythm guitarist and singer, formed RatDog, he tapped Karan as his lead guitarist. He moonlights with his side group, Jemimah Puddleduck. He doesn't need any help on this CD, but it's enriched by some prestigious guest musicians - the late Delaney Bramlett joins voices with Karan and plays dobro on Robert Johnson's blues classic "Love in Vain." And Little Feat's Bill Payne sweetens Karan's uptempo "Rock Your Papa" with Wurlitzer organ. The Persuasions add background vocals. Karan nods to Marin rock history with "Annie Don't Lie," a New Orleans-flavored tune written by Alex Call, former lead [...]

2009-06-26T11:09:49-07:00June, 2009|Oral Cancer News|

Anti-smoking bill a victory for kids

Source: www.blackvoicenews.com Author: Dr. Ernest Levister, Jr The health risks of tobacco are well known, yet the rates of smoking and using chewing tobacco continue to grow. Many young people pick up these habits every year — in fact, 90% of all adult smokers started when they were kids. Each day, more than 4,400 kids become regular smokers. So it was particularly encouraging to see President Barack Obama this week surrounded by children from the Campaign for Tobacco Free Kids sign the strongest anti-smoking measure ever, calling it “an extraordinary accomplishment that will help keep children from getting hooked on cigarettes”. This landmark legislation is a clear victory for kids. With an estimated 3,500 young people smoking their first cigarette each day, the ban on flavorings alone could have significant health benefits. Mr. Obama cited his own long struggle to quit the cigarettes he got hooked on as a teenager and praised the bill for providing critically needed protections for kids. Studies show that African Americans smoke fewer cigarettes when compared to Caucasians, but they share a far greater burden of smoking related health problems. It’s important to make sure kids understand the dangers of tobacco use. Smoking is the leading cause of preventable deaths in the United States, and can cause cancer, heart disease, and lung disease. Chewing tobacco (smokeless or spit tobacco) can lead to nicotine addiction, oral cancer, gum disease, and an increased risk of cardiovascular disease, including heart attacks. Kids might be drawn to smoking and [...]

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