Oral Cancer News – Page 224 – The Oral Cancer Foundation News Archive

Nicotine-delivering e-cigarettes under fire

Source: Courier Journal By: Patrick Howington Sean Howard smoked cigarettes for 14 years until he found something new — an electronic cigarette that delivers the nicotine he craves but not the deadly toxins from cigarette smoke. Now Howard, 28, of Lexington, said he breathes better, can exercise again, and “I don’t smell like a cigarette.” A server at a local country club, Howard said he has gone back and tried cigarettes a couple of times in the year since he quit them, “and now I can’t stand the things. … I actually don’t know how I smoked them.” Howard is among the growing number of advocates of e-cigarettes — plastic or metal tubes that contain a nicotine solution but no tobacco. A battery heats the liquid into a vapor for inhaling. Sold under names like “Health E-Cigarettes” and “SmokeAnywhere” that suggest harmlessness and the ability to evade indoor smoking bans, e-cigarettes don’t require matches and don’t emit toxic smoke — but they’ve still drawn plenty of fire. In court filings and enforcement actions, federal regulators and some states have lined up with medical organizations who say e-cigarettes’ safety hasn’t been proved. While their sale is legal in most of the U.S., including Kentucky and Indiana, several states have banned e-cigarettes or are considering it. (They are not covered under Louisville and Lexington’s indoor smoking bans, though, and there are no current plans to add them.) Advocates of the product, and some medical experts, say the devices could save thousands of [...]

Oral Cancer Foundation News Team - A2010-10-22T14:28:38-07:00October, 2010|Oral Cancer News|

HPV Causing “Slow Epidemic” of Oral Cancers

Source: Medscape Today By: Janis C. Kelly October 21, 2010 — Human papillomavirus (HPV) is a risk factor for oropharyngeal squamous cell carcinoma (OSCC), and might account for the steady increase in OSCC incidence, even in subjects who do not smoke or consume alcohol, according to Swedish researchers. A review of recent studies, conducted by Trobjorn Ramqvist, MD, and Tina Dalianis, MD, PhD, and published online October 13 in Emerging Infectious Diseases, suggests that changes in sexual practices are behind the surge in OSCC cases linked to sexually transmitted HPV. The key factors appear to be multiple sex partners, starting sexual activity at a younger age, and increased oral sex. The data are startling. For example, from 1970 to 2002, tonsillar cancer (which is the most common OSCC) increased in Stockholm, Sweden, by 2.8-fold, and by 2006/07, 93% of all tonsillar cancers in that city were HPV-positive. Dr. Dalianis, who is professor of tumor virology and the head of the Department of Oncology–Pathology at Karolinska Institutet in Stockholm, told Medscape Medical News that "we realized that there was an increase in HPV-induced tonsillar cancer, but we did not realize it was so eminent until we separated the 2 groups (HPV-negative and -positive tonsillar cancer cases) the way we did." The most common OSCC is tonsillar cancer, followed by base of tongue cancer. Overall 5-year survival for OSCC is about 25%, and HPV-positive OSCC generally has better clinical outcomes than HPV-negative disease. Dr. Dalianis said that HPV (most commonly type 16) [...]

Oral Cancer Foundation News Team - A2010-10-22T11:17:11-07:00October, 2010|Oral Cancer News|

Penthouse Founder Bob Guccione Dead at 79

Source: ThirdAge News Penthouse founder Bob Guccione died on Wednesday in Texas after a long bout with lung cancer, his family said. He was 79 years old. Guccione also suffered from oral cancer, the Oral Cancer Foundation says. “My cancer was only a tiny tumor about the size of an almond at the base of my tongue,” he explained in an intervie with New York Magazine. “The cure is probably every bit as bad as the disease. It’s affected my ability to swallow . . . the mobility of my tongue . . . it makes it very difficult for me to talk...” The Wall Street Journal reported his family said in a statement Guccione died at Plano Specialty Hospital in Plano. Guccione created Penthouse in 1965, immediately setting it apart from Hugh Hefner's Playboy magazine through its more graphic photos of unclothed women and less reliance on the written word. If Playboy was the publishing world's version of the Beatles, Penthouse was the Rolling Stones. "Unlike his future arch-rival Hugh Hefner, he did not suffer from sexual shyness and repression," John Heidenry, a former Penthouse Forum editor wrote in his book "What Wild Ecstasy." "He liked girls, pure and simple, like any average healthy Italian boy from New Jersey, and he was no virgin." Guccione diversified into other magazines, movies and other ventures and his fortune at one time was estimated at $400 million but Penthouse's popularity waned with the advent of Internet pornography.

Oral Cancer Foundation News Team - A2010-10-22T08:48:47-07:00October, 2010|Oral Cancer News|

The Major Component In Tumeric Enhances The Effect Of Chemotherapy In Suppressing Head And Neck Cancers

Curcumin, the major component in the spice turmeric, when combined with the drug Cisplatin enhances the chemotherapy's suppression of head and neck cancer cell growth, researchers with UCLA's Jonsson Cancer Center have found. A naturally occurring spice widely used in South Asian and Middle Eastern cooking, Turmeric has long been known to have medicinal properties, attributed to its anti-inflammatory effects. Previous studies have shown it can suppress the growth of certain cancers, said Dr. Marilene Wang, a professor of head and neck surgery, lead author of the study and a Jonsson Cancer Center researcher. "Head and neck cancers, particularly cases diagnosed in a later stage, are terrible cancers that often require very radical surgeries and chemotherapy and radiation," Wang said. "They often don't present until late, and the structures in the head and neck are so vital that our treatments often cause disfigurement and severe loss of function. So using non-toxic curcumin as a treatment was a very appealing idea." The study, done in cells in Petri dishes and then in mouse models, appears in the October issue of the journal Molecular Cancer Therapeutics. In India, women for years have been using turmeric for medicinal purposes, as an anti-aging agent rubbed into their skin, to treat cramps during menstruation, as a poultice on the skin to promote wound healing and as an additive in cosmetics, said scientist Eri Srivatsan, an adjunct professor of surgery and a Jonsson Cancer Center researcher who, along with Wang, has been studying curcumin and its [...]

Oral Cancer Foundation News Team - A2010-10-21T15:06:19-07:00October, 2010|Oral Cancer News|

On the Call: Altria Group CEO Michael Szymanczyk

Source: Business Week Richmond, VA Like other tobacco companies, Altria Group Inc. is focusing on cigarette alternatives such as cigars, snuff and chewing tobacco for sales growth as tax increases, smoking bans, health concerns and social stigma make the cigarette business tougher. The smokeless tobacco category is growing at about 7 percent a year, but still remains small compared with cigarettes. The parent company of the nation's biggest cigarette maker, Philip Morris USA, said Wednesday that volumes for its smokeless tobacco segment, which includes Copenhagen and Skoal, as well as Marlboro Snus, grew 16.4 percent in the third quarter and revenues excluding excise taxes increased about 11 percent to $363 million. In a conference call with analysts regarding Altria's third-quarter earnings, CEO Michael E. Szymanczyk talked about the company working with retailers to better align their shelf space with changes in the tobacco industry. QUESTION: Is the investment to help retailers reallocate their space and improve their display units for smokeless products meaningful to call out? RESPONSE: This is a category that has grown pretty substantially here over the last few years, but in retail stores, there hasn't been any significant movement in the space. At the same time, the cigarette category has declined in volume. And while inventories have come down in the cigarette business, the actual physical space devoted to cigarettes hasn't meaningfully changed. There's a good opportunity to play catch-up here. ... We're helping retailers redistribute their space so it's more consistent with their sales, and that [...]

Oral Cancer Foundation News Team - A2010-10-21T12:27:20-07:00October, 2010|Oral Cancer News|

Turmeric makes chemo more effective

Source: timesofindia.indiatimes.com Author: staff Researchers with UCLA's Jonsson Cancer Center have found that curcumin, the major component in the spice turmeric, when combined with the drug Cisplatin enhances the chemotherapy's suppression of head and neck cancer cell growth. In India, women for years have been using turmeric for medicinal purposes, as an anti-aging agent rubbed into their skin, to treat cramps during menstruation, as a poultice on the skin to promote wound healing and as an additive in cosmetics, said scientist Eri Srivatsan, an adjunct professor of surgery and a Jonsson Cancer Center researcher. Srivatsan, along with Dr. Marilene Wang, a professor of head and neck surgery, lead author of the study and a Jonsson Cancer Center researcher, has been studying curcumin and its anti-cancer properties for six years. A 2005 study by Wang and Srivatsan first showed that curcumin suppressed the growth of head and neck cancer cells, first in cells and then in mouse models. In the animal studies, the curcumin was applied directly onto the tumours in paste form because it did not dissolve in saline, which would have allowed it to be injected. In need of a better way to deliver the curcumin, the team collaborated with Dr. Kapil Mehta of M.D. Anderson Cancer Center and found that encapsulating the curcumin in a liposome, an artificially prepared vehicle that enclosed the spice component within its membrane, made the treatment injectable. The curcumin was injected into the tail vein of a mouse, where it circulated into the [...]

Oral Cancer Foundation News Team - A2010-10-20T08:54:24-07:00October, 2010|Oral Cancer News|

Latest generation VELscope device approved for sale by Health Canada

Source: www.sfgate.com Author: staff LED Dental Inc. announced today that its VELscope Vx Enhanced Oral Assessment system was granted a medical device license and approved for sale by Health Canada. The VELscope Vx system's unique cordless design and affordable pricing make it easier than ever for dental practices to detect oral cancer and other forms of oral disease. The first-generation VELscope device was introduced in 2006, with the second-generation version launching two years later. In total, LED Dental has sold almost 6,000 units of the two devices, which have been used to conduct almost 10 million enhanced oral soft tissue exams worldwide. Oral soft tissue exams not only help detect all types of oral disease but are also a key element of an oral cancer screening protocol. Today, VELscope fluorescence visualization technology is used to conduct more enhanced oral exams than any other detection technology in the world. "We are extremely excited about the potential of the VELscope Vx system to significantly increase the number of dental practices conducting oral cancer screenings," said Peter Whitehead, founder and CEO of LED Dental. "The device's portability makes it easy to transport between operatories within the dental practice, and its attractive pricing makes it possible for practices to charge very low exam fees to their patients." Oral cancer kills one North American every hour of every day. According to the SEER database, oral cancer has a higher mortality rate than several better-publicized cancers, such as cervical cancer and testicular cancer. Some oral cancers [...]

Oral Cancer Foundation News Team - A2010-10-20T08:46:07-07:00October, 2010|Oral Cancer News|

Dead man will be remembered for spreading oral cancer

Source: The Gawker/ WSJ Author: Steven Miller Louis Bantle, the former marketing director and chairman of U.S. Tobacco, died earlier this month at the age of 81 from emphysema and lung cancer. Bantle was most famous for convincing millions of teenagers to dip. The WSJ chroniclesBantle's work from the 1960s through the 1990s, during which time he helped turn snuff into a billion-dollar business and tripled its use among 18-24 year-olds. "We must sell the use of tobacco in the mouth and appeal to young people," he said, according to the minutes of a marketing meeting in 1968. "We hope to start a fad." "If you go to high school in Texas and you don't have a can of snuff in your pocket, you're out," Mr. Bantle told Forbes in 1980. Your legacy will live on, Mr. Bantle. Original Article from the WSJ: Louis Bantle made dipping snuff into a national pastime. Mr. Bantle, who died Oct. 10 at age 81 after a long struggle with lung cancer and emphysema, was chairman of United States Tobacco Co. for two decades beginning in 1973, a period that saw an explosion in snuff's popularity, particularly among younger users. In the 1970s, sales of the company's Skoal and Copenhagen tobaccos were relatively small and concentrated in the upper Midwest, where Scandinavian woodcutters had spread the smokeless habit in the 19th century. Mr. Bantle ramped up advertising featuring football and rodeo star Walt Garrison and other rugged athletes. He introduced a series of "starter" [...]

Charlotte Parker2010-10-20T08:39:52-07:00October, 2010|Oral Cancer News|

Dentistry’s Schmidt and Boston Biomedical Share $1.25mil NIH Grant for Cancer Pain Research

Source: Iewy Author: Staff The National Institute of Dental and Craniofacial Research, part of the National Institutes of Health (NIH), has awarded a joint, five-year, $1.25 million grant to Dr. Brian L. Schmidt, a Professor of Oral and Maxillofacial Surgery at the NYU College of Dentistry, and Dr. Markus Hardt, a protein chemist at the Boston Biomedical Research Institute, for a study of the molecular mechanisms of oral cancer pain. The ultimate goal of the research is to spur the development of more sophisticated analgesics (pain medications) to alleviate the pain that is so often manifested in patients with oral cancer. “Oral cancer is a logical place to start when seeking clues about cancer pain,” Dr. Schmidt said. “To begin, oral cancer is very painful. In fact, pain is the most common presenting symptom associated with this cancer. Secondly, oral cancer is painful at the primary site, not just at sites of metastasis as is the case in almost all other cancers. Lastly, the primary site of the oral cancer is readily accessible, enabling us to directly sample the cancer microenvironment.” Dr. Schmidt hypothesizes that the cause of oral cancer pain and pain generated by other cancers may be produced along similar molecular pathways in the body. Oral cancer pain, like many other kinds of cancer pain, is triggered by specific actions. Just as oral cancers can cause patients to feel pain in the oral cavity when they speak, other cancers generate pain during mechanical stimulation. For example, if a [...]

Charlotte Parker2010-10-18T14:53:54-07:00October, 2010|Oral Cancer News|

Virus Behind Oral Cancer Epidemic

Study Shows 'Startling Increase' in Oral Cancer Is Linked to Sexually Transmitted HPV Source: WebMD Health News By: Daniel DeNoon Researchers warn of an ongoing epidemic of oral cancer caused by the sexually transmitted human papillomavirus (HPV). A study in Stockholm, Sweden, finds that cases of oral cancer -- primarily cancer of the tonsils -- increased sevenfold from 1970 to 2007. They find that while HPV caused only 54% of oral cancers from 1998-1999, it caused 84% of these cancers in 2006-2007. "It looks like HPV-positive oral cancers are rising quite sharply in the past 10 years, while HPV-negative oral cancers went down. That is why we say it is an epidemic," study leader Tina Dalianis, MD, PhD, professor of tumor biology at Sweden's Karolinska Institute, tells WebMD. HPV is a well-known cause of cervical cancer. But researchers have only recently begun to appreciate its role in oral cancer, says HPV-oral cancer expert Gypsyamber D'Souza, PhD, of Johns Hopkins Bloomberg School of Public Health. "Yes there is a startling increase in the incidence of oropharyngeal cancer, and that increase is being driven by HPV," D'Souza tells WebMD. "But while many experts agree that there's an epidemic rise in HPV-related oral cancer, the cancer remains rare." The risk of developing oral cancer increases with the lifetime number of oral or vaginal sex partners, but many people with HPV-related oral cancer have five or fewer lifetime sexual partners. Men are more likely to get oral cancer than are women, and people with [...]

Oral Cancer Foundation News Team - A2010-10-18T09:25:43-07:00October, 2010|Oral Cancer News|