The End-of-Life Paradox

Source: The Huffington Post It seems that whenever Marian visits her dad, he wants to go over certain things: where his will is located, where to find his stocks and bank book, and even where to find the charcoal suit that he wants used when he is laid out in his casket. To Marian, such conversations are morbid, distressing and perplexing. At 82, her father is relatively healthy, independent and maintains an active life. Why does he always seem to focus on death -- especially when she is around? Often adult children experience what I call this end-of-life paradox. Their older parents want to speak about the logistics of death in detail. Or, maybe they want to review end-of-life care plans contained in advance directives, just at the time when it is most difficult emotionally and spiritually for their adult child to listen to such conversations. The end-of-life paradox results from the different places the generations are in their own spiritual development and how each makes sense both of life and death. Older persons recognize that even if they are active and healthy, they are nearing the end point of life. Victor Marshall, a sociologist, used the term "awareness of finitude" to describe the appreciation for the life cycle that older people may exhibit. Death is perceived as closer. This does not mean that they expect to die immediately, but rather that they realize that death is part of life. They are reluctant to plan too far into the future. [...]

Anti-Vaccine Groups Continue to Cause National Problems

The United States seems to be on track to have more measles cases than any year in more than a decade, with virtually all cases linked to other countries, including Europe where there's a big outbreak. Already there have been 89 cases reported so far. The U.S. normally sees only about 50 cases of measles in a year thanks to vaccinations. Health officials are reluctant to make predictions, but acknowledge the pace of reports is unusually hot. "It's hard to say, but we're certainly getting a lot," said Dr. Greg Wallace, who leads the measles, mumps, rubella and polio team at the U.S. Centers for Disease Control and Prevention. Europe, especially France, has been hit hard by measles, with more than 6,500 cases reported in 33 nations. International health officials are blaming it on the failure to vaccinate all children. Just about all U.S. outbreaks were sparked by people bringing it here from other countries. This week, international health officials posted an alert urging travelers everywhere to get the recommended two doses of vaccine before flying overseas. "The risk of getting infection is very high," said Dr. Cuauhtemoc Ruiz Matus, an immunization expert with the Pan American Health Organization. In the U.S., the worst year for measles in the last decade was 2008, when 140 cases were reported. There have been no measles deaths this year, but health officials warn the disease can be dangerous. Measles is highly contagious and up to 90 percent of people exposed to an infected [...]

Spouses of Head/Neck Cancer Patients More Inclined to PTSD

Source: MedScape Today Partners of patients with newly diagnosed head and neck cancer are significantly more likely to meet research criteria for post-traumatic stress disorder (PTSD) than patients themselves, according to a study presented here at the Society of Behavioral Medicine 32nd Annual Meeting and Scientific Sessions. Donna Posluszny, PhD, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, and colleagues from there and from the University of Texas, Arlington, Texas, found that 8 of 20 partners of patients with head and neck cancer (20%) had a mean score on the PTSD Checklist (also known as the PCL) of 50 or higher, compared with only 2 of 40 patients (5%). Patients who score at least 50 on the PCL meet the criteria for PTSD. "This is not a formal diagnosis of PTSD but for research purposes, a score of 50 or higher is meaningful," Dr. Posluszny told delegates. "And we were very surprised to find that partners of patients with newly diagnosed head and neck cancer experience greater amounts of traumatic stress than patients themselves do." For the study, investigators recruited 40 dyads (2 individuals regarded as a pair) where the partner was considered to be a "romantic" partner. Some 78% of the patients were male, while most partners were female; all but a small minority were married. Almost all were white, and, as a cohort, they were somewhat better educated and made more money than the majority of patients with head and neck cancer. Sixty-five percent of them also had [...]

University of Michigan scientists are at the forefront of cancer stem cell research

Source: www.annarbor.com Author: Betsy de Parry Nine years ago, I walked into the University of Michigan Comprehensive Cancer Center for the first time and walked out as a terrified cancer patient. During all the months that I was in treatment, I never saw the labs or gave a thought to the research that was being conducted in them. And then, when standard treatment failed to stop my cancer, I was rescued by a new therapy that was pioneered at U-M by Dr. Mark Kaminski, and I began to appreciate those labs we patients never see and the discoveries that are made in them. Discoveries, after all, save lives. Indeed, labs are hotbeds of discovery. And the labs at Michigan are turning out stem cell research that is revolutionizing the way many cancers are treated. I know — stem cells are two words that stir passion and debate, but there are stem cells... and there are stem cells. What distinguishes them from other cells is their ability to divide and make exact copies of themselves indefinitely, a process called self-renewal, and their ability to change, or differentiate, into other types of cells. Embryonic stem cells — the controversial ones — have unlimited potential to become any type of cell. Adult stem cells — with which we're born — are more restricted than embryonic stem cells in terms of what they can become, but they can still differentiate. For example, adult stem cells in our bone marrow, known as hematopoietic cells, constantly [...]

A life less healthy: tobacco’s daily toll

Source: www.napsnet.com Author: staff When people think of the consequences of smoking and tobacco use, often-fatal diseases such as Stage IV lung cancer most commonly come to mind. But there is another side to tobacco use. About 8.6 million people in the U.S. are currently living with tobacco-related illnesses. Chronic bronchitis, emphysema and oral cancer can be debilitating illnesses—illnesses that can rob people of opportunities and that can affect their daily lives. For many of these people, tobacco use means no longer being able to enjoy eating, be physically active or spend quality time with family. Thomas Cook, 51, knows the effects firsthand. Cook started smoking at age 13 and was diagnosed at 38 with Stage IV larynx cancer. “When you get sick from using tobacco, your whole life changes. Things will never and can never be the same. Not one day goes by that I don’t think about cancer. All I have to do is look in the mirror and there it is,” said Cook, who appeared in the Emmy-nominated truth youth smoking prevention campaign commercial, “Singing Cowboy,” in 2006. Christine Brader smoked for almost 28 years until she was diagnosed with oral cancer. Brader, 48, survived three bouts of oral cancer in three years. She lost 65 pounds from not being able to eat and has had more surgeries than she can count. She lost her pets because she was too sick to care for them. She also lost her house, her job and in her words, “my [...]

Michael Douglas turns alarming diagnosis into resources for Montreal hospital

Source: TheStar.com The atmosphere was electric when elegant, beleaguered actor Michael Douglas appeared at New York Fashion Week with his beautiful wife, Catherine Zeta-Jones. The glamourous couple had come out to support their designer pal Michael Kors, whose 30th anniversary show was part of the February shows at Lincoln Center. Like many fans, I breathed a sigh of relief when I saw the 66-year-old actor, looking chic in his tailored cashmere. Last summer, Douglas had been diagnosed with Stage 4 throat cancer. We had all said our prayers. This week, in gratitude to the doctor and hospital that helped save his life, Douglas appeared at a gala benefit in Montreal for the McGill Head and Neck Cancer Fund. But he was flying solo: Zeta-Jones, who was recently diagnosed and treated for bipolar II disorder, was at work on a film in the United States. Their family has gone through some unspeakably tough trials, but it appears things are happily back on track. At the gala, the dapper Douglas posed for countless pictures and chatted with guests, adamant about spreading the word that cancer can be beaten and a positive attitude is key. Free of the disease for three months now, Douglas told the crowd that his cancer had gone undiagnosed by doctors in the U.S. While on vacation at his farm outside Mont Tremblant in 2010, Douglas sought a second opinion from Dr. Saul Frenkiel, a head and neck surgeon at Montreal’s Jewish General Hospital. The chilling news: Douglas had [...]

Lower survival rate for head and neck cancer patients who suffer from stress and depression

Source: Medical News Today Studies have shown that stress can affect the immune system and weaken the body's defense against infection and disease. In cancer patients this stress can also affect a tumor's ability to grow and spread. However, the biological mechanisms that underlie such associations are not well understood. Now, researchers at Fox Chase Cancer Center find that poor psychosocial functioning is associated with greater vascular endothelial growth factor (VEGF) expression - a signaling protein that not only stimulates tumor growth, but is also associated with shorter disease-free survival in head and neck cancer patients. "There is research showing that high VEGF expression in other cancers, such as ovarian, is associated with psychosocial factors," says Carolyn Fang, Ph.D., Co-Leader of the Cancer Prevention and Control Program at Fox Chase, who presented the study at the 32nd Annual Meeting & Scientific Sessions of the Society of Behavioral Medicine on Thursday, April 28th. "This information coupled with what we already know about VEGF promoting tumor aggressiveness and poorer prognosis in head and neck cancer patients, certainly gave us a reason to look at this biomarker." VEGF not only plays a pivotal role in angiogenesis, but it is also regulated by stress hormones and key cytokines - a category of signaling molecules used extensively in intercellular communication. In the current study, Fang and colleagues looked at 37 newly diagnosed, pre-surgical head and neck cancer patients, to see if psychosocial functioning, such as perceived stress and depressive factors, was associated with VEGF, a [...]

Oral Cancer…what does sex have to do with it?

Source: DentistryIQ.com The answer is … plenty! This issue will focus on oral cancer awareness. While there are many topics we can delve into regarding this dreadful disease, we will focus on a few topics. We will share two personal and very poignant stories. Kim Anzalotti, Bill Wislon, and Eva Grayzel impart information that will move you and make you think about your daily in-office procedures. JoAnn Gurenlian, RDH, PhD, will share insights on the human papillomavirus, or HPV, a sexually transmitted virus, and its relationship to oral cancer. And last, but certainly not least, Jamie O'Day, Treatment Facilities Coordinator, The Oral Cancer Foundation Inc., The Bruce Paltrow Oral Cancer Fund, will share her insight on oral cancer screening and the need for a thorough examination. One personal story is shared by Eva Grazel, an international motivational speaker, author, performer, and cancer survivor. I had the pleasure of meeting Eva a number of years ago. In 1998 at age 33, Eva, a non-smoker, saw a number of dentists and physicians for over two years for an “ulcer” on her tongue that became larger and more painful, without any resolution. She was finally diagnosed with advanced oral cancer, Stage IV squamous cell carcinoma, on the lateral border of her tongue. After the many missed opportunities for diagnosis, Eva was given a 15% chance of survival. While her late stage diagnosis is not uncommon, her recovery was unique, as she beat the odds. After diagnosis, Eva underwent a partial tongue reconstruction, a [...]

Michael Douglas compliments Canadian health care

Source: The Globe and Mail Hollywood star Michael Douglas offered up high praise for Canadian health care on Tuesday in a nod to the Montreal medical staff who made the breakthrough diagnosis of his throat cancer. Mr. Douglas said a doctor at Montreal’s Jewish General Hospital detected the disease that had eluded specialists in the United States. In gratitude, the Oscar winner agreed to add a new role to his résumé: fundraising draw for Canadian medical research. The actor travelled to Montreal from New York on Tuesday to act as leading man for McGill University’s annual fundraiser for head and neck cancer research. In an interview at a Montreal ballroom where he was about to be honoree for the evening, a dapper-looking Mr. Douglas said getting the news was like being “hit by a truck.” Yet when it came, he said, he had suspected it for months. He said he’d been having bothersome symptoms over the course of nine months: pain in his throat, in the back of his gums and up toward his ears. He consulted various ear, nose and throat doctors and was prescribed antibiotics for what was thought to be an infection. But while summering last year in Quebec’s Mont Tremblant, where he shares a home with his wife, actress Catherine Zeta-Jones, Mr. Douglas went to see Dr. Saul Frenkiel at the Jewish General, a McGill teaching hospital. The doctor put a tongue depressor in the actor’s throat. “I looked in his eyes and I immediately knew [...]

U of A study finds ways to help end dry mouth in cancer patients

Source: e! Science News For patients suffering from cancer in the mouth or throat, a recent study shows that a treatment called submandibular gland transfer will assist in preventing a radiation-induced condition called xerostomia. Also known as dry mouth, xerostomia occurs when salivary glands stop working. University of Alberta researcher Jana Rieger likens the feeling of xerostomia to the experience of the after-effects of having surgery and anesthetic—but the feeling is permanent. While the importance of healthy saliva glands may be an afterthought for some patients when battling cancer, the long-lasting effects create a number of problems for them when they are in remission. "We need saliva to keep our mouths healthy," said Rieger. "Without saliva, people can lose their teeth, dentures don't fit properly and the ability to swallow and speak is severely altered." The study conducted by Rieger, a speech language pathologist in the Faculty of Rehabilitation Medicine, looked at functional outcomes—speech changes, swallowing habits and the quality of life of patients with mouth and throat cancers—as they received two different types of treatments prior to and during radiation. The first group of patients underwent the submandibular gland transfer. This method was pioneered by Hadi Seikaly and Naresh Jha at the University of Alberta in 1999. The transfer involves moving the saliva gland from under the angle of the jaw to under to the chin. Prior to this procedure, the saliva gland was in line for the radiation. Seikaly says, "Most patients, when they are cured from cancer, [...]

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