Broccoli may prevent oral cancer as clinical tests set to start on humans

Source: www.mirror.co.uk Author: staff The much-maligned green vegetable deserves more respect as lab tests show extracts of sulforaphane reduced tumours in mice. Broccoli could soon protect people from cancer of the mouth, throat, neck and head in a new treatment known as “green chemoprevention.” Cruciferous vegetables such as broccoli, cabbage and garden cress have a high concentration of sulforaphane. Previous studies, including large-scale trials in China, have shown sulforaphane helps mitigate the effects of environmental carcinogens. Now lab tests have shown extracts made from broccoli sprout protected mice against oral cancer. American scientists now plan to carry out clinical trial on patients at high risk of a recurrence of head and neck cancer. They will be given capsules containing broccoli seed powder to determine if they can tolerate the regimen and whether it has enough of an impact on their oral lining to prevent cancer. Associate professor Dr Julie Bauman of the University of Pittsburgh said: “People who are cured of head and neck cancer are still at very high risk for a second cancer in their mouth or throat, and, unfortunately, these second cancers are commonly fatal. “So we’re developing a safe, natural molecule found in cruciferous vegetables to protect the oral lining where these cancers form.” The study involved testing sulforaphane in the laboratory when over several months mice predisposed to oral cancer were given the extract and found that it significantly reduced the incidence and number of tumours. Professor of medicine Dr Daniel Johnson at Pitt’s School [...]

HPV Shots for Boys Might Cut Cancer Costs

Source: MedPageToday.comAuthor: Charles Bankhead - Canadian study suggests vaccination would save money by preventing oropharyngeal cancer. Widespread vaccination of boys against human papillomavirus (HPV) infection proved to be a cost-saving approach to prevent subsequent head and neck cancer, according to data based on the Canadian health system. A 70% immunization rate and 99% efficacy with the quadrivalent vaccine Gardasil might reduce costs by as much as $28 million ($22.2 million U.S.). Reducing uptake and efficacy to 50% still might save $8 million ($6.35 million U.S.), Lillian L. Siu, MD, of Princess Margaret Cancer Center in Toronto, and co-authors reported online in Cancer. "According to the findings of this preliminary analysis, HPV vaccination for boys aged 12 years may be a cost-effective strategy in relation to the prevention of oropharyngeal cancer alone, strengthening the cost-effectiveness of a male vaccination program," the authors concluded. "The argument for funding male HPV vaccination in North America is becoming more compelling given the benefits of reductions in genital warts and anal cancer and the potential benefits for the female population because of increased herd immunity. "Prospective data collection for male HPV vaccination and oropharyngeal cancer may validate these findings in the future." The data are consistent with other studies showing cancer benefits for HPV immunization, although the Canadians are the first to suggest that vaccination saves money, U.S. sources told MedPage Today. Background Initial clinical studies of HPV vaccination and national vaccination programs targeted girls and young women. Only recently has the focus expanded to include immunization of adolescent boys. [...]

2015-04-14T10:42:30-07:00April, 2015|Oral Cancer News|

Legal loopholes allow big tobacco companies to target young children with new products

Source: http://www.contracostatimes.comAuthor: Sen. Mark Leno & Tony Thurmond   With smoking now widely known as the nation's No. 1 preventable killer, Big Tobacco is targeting our kids with new products that give an illusion of more safety but carry the age-old motive to hook kids on tobacco at a young age. Preventing children from picking up nicotine addiction is the best way to keep them free of tobacco-related disease for life. That's why we've each introduced bills that seek to curb youth usage of smokeless (chewing) tobacco and e-cigarettes. Last year, many were shocked when Hall of Famer Tony Gwynn, who played for the San Diego Padres, died from cancer of the salivary glands that was related to decades of smokeless tobacco usage.  Former World Series hero Curt Schilling, who helped propel the Arizona Diamondbacks and Boston Red Sox to championships, has blamed his bout with mouth cancer on chewing tobacco.  Use of chewing tobacco by professional athletes sends the wrong message to our kids, but nonetheless a powerful one. Researchers at the Harvard School of Public Health have found that the use of smokeless tobacco by players has a powerful "role model effect" on youths, particularly young males.  It's no wonder then that while overall rates of smoking have declined thanks to several decades of intense educational programs, smokeless tobacco rates have remained stubbornly high among youth. One in every 6 high school boys report regular usage. Assembly Bill 768 bans smokeless tobacco at all ballparks in California with organized baseball, [...]

2015-04-13T12:22:32-07:00April, 2015|Oral Cancer News|

Breath test for detecting head and neck cancer

Source: http://medicalxpress.com/ Author: provided by Ecole Polytechnique Federale de Lausanne A portable device can detect the presence of certain types of cancer in people's breath. Tested on patients, the new device was developed in part by EPFL researchers as part of an international collaboration. Inhale, then exhale. This simple act could now save lives. A technology developed in part at EPFL can quickly identify the presence of a head and neck cancer, such as of the throat or mouth by analysing people's breath. The new device, equipped with extremely sensitive sensors, has been tested on patients and operates with a computer or even a mobile phone. It's an innovative tool for the early diagnosis of tumours. Very few routine exams exist to detect cancer. Yet this disease is the third leading cause of death worldwide. Most tumours are found relatively late, which makes recovery less likely. Cancer "signals" its presence in human breath At SAMLAB in Neuchâtel, under the direction of Nico de Rooij, a team of researchers including Frédéric Loizeau, a doctoral student at the time, developed very precise micro-sensors able to distinguish the breath of a healthy patient from that of a sick one. The scientists' starting point was the observation that human breath contains not only air, but also hundreds of volatile organic compounds (VOCs) whose presence and concentration vary depending on the patients' state of health. The metabolism of cancerous cells is different from that of healthy cells, and the two types of cells produce different [...]

Nova Scotia to include boys in HPV vaccination schedule

Source: www.theglobeandmail.com Author: Kelly Grant, Health Reporter Boys in Nova Scotia will begin receiving free vaccinations against the human papillomavirus next fall, a move that makes the Maritime province only the third in Canada to extend public funding of the cancer-thwarting shot to all children, regardless of gender. In the budget unveiled on Thursday, Nova Scotia’s Liberal government announced it would make the HPV vaccine available to Grade 7 boys as part of the regular school-based immunization program. The expansion is expected to cost $492,000 a year. Every province in Canada already covers the HPV vaccine for girls in an effort to prevent genital warts and cervical cancer, both of which can be caused by some strains of the virus, which is transmitted through sex and skin-to-skin contact. But in recent years, oncologists and major health organizations – including the Canadian Cancer Society and the National Advisory Committee on Immunization – have begun calling for HPV vaccinations for boys, too. Until this week, only Prince Edward Island and Alberta had heeded that call with a publicly funded program. HPV can lead to cancers of the penis, anus, oral cavity and throat in men, as well as genital and anal warts. “We have a vaccine. It can prevent cancers in men and women, so we want Canadians to be vaccinated against it, because we can actually prevent cancers from starting in the first place,” said Robert Nuttall, the assistant director of cancer control policy at the Canadian Cancer Society. Nova Scotia’s [...]

FDA Advisory Committee hesitates to endorse message of safe smokeless tobacco

Source: www.medpagetoday.com Author: Shannon Firth An FDA advisory panel were reluctant to recommend a gentler warning label for one brand of smokeless tobacco products at a committee hearing on Friday. Swedish Match North America (SMNA), the first company to be considered for a modified risk tobacco designation by the FDA, is asking to replace a current label warning, "This product is not a safe alternative to cigarettes," with this: "Warning: No tobacco product is safe, but this product presents substantially lower risks to health than cigarettes." It also wants to drop warnings required for other smokeless tobacco products about oral cancers, tooth loss, and gum disease. In a key vote, the eight-member FDA's Tobacco Products Scientific Advisory Committee split 4-4 on whether the claim that snus offer a "substantially lower risk" claim relative to cigarettes is justified. Many members said the health risks were lower for certain tobacco-related illnesses, but not for all health concerns. Those who disputed the claim argued that it could not be taken as a "global statement" -- as there are known risks to pregnant women and uncertain risks for adolescents. As for the proposed label change, the whole committee agreed that the sponsor's statements would not suffice. Gary Giovino, PhD, chair of the department of Community Health and Health Behavior at the State University of New York at Buffalo, felt the statement was "dismissive of the health risks." The word "but" in any sentence seems to negate the first half, he said. Snus is a [...]

Curt Schilling: Letter to my younger self

Source: www.theplayerstribune.com Author: Curt Schilling Dear 16-year-old Curt, Tomorrow at lunch, a kid is going to dare you to take a dip of Copenhagen. If you say yes, like I did, you’ll be addicted for the rest of your life. Well, the rest of your life up to the point when you are diagnosed with cancer. I get what you’re thinking. You’re 16 — you’re invincible, just like all your buddies. If you were to jump ahead 33 years, you couldn’t write a better dream than the one your life is going to be. With one exception. If you say yes tomorrow, you will become addicted to chewing tobacco and you will get mouth cancer. I’m going to tell you a little story that I think may help guide you. (I saw this on a TV series called The West Wing — great show, you’re going to love it one day — and it very much rings true). There was a man — we’ll call him Joe. Joe lived in the same house his entire life. One day, a huge storm came. He turned on the radio: Prepare for torrential rains and deadly flash flooding. Everyone should evacuate to safety immediately. See, Joe was a devout Christian. He had the Lord in his life for as long as he could remember. Church every Sunday, prayed twice a day. “My faith in God is resolute. He will save me,” Joe thought. The rain kept coming down. About two hours later, water [...]

The Oral Cancer Foundation Launches April Oral Cancer Awareness Month

Source: Yahoo NewsAuthor: The Oral Cancer Foundation  NEWPORT BEACH, Calif., April 9, 2015 /PRNewswire-USNewswire/ -- April is Oral Cancer Awareness Month. 2015 marks the 16th year that The Oral Cancer Foundation has lead the effort to raise awareness of this disease and the need for an annual screening. OCF has learned that although we accomplish a great deal as an organization, we can do so much more through the formation of strategic relationships with those who share our values and goals. OCF is grateful to the thousands of private dental offices that make time on multiple days during the month of April to offer free screenings to members of the public in their local communities across the nation. Besides the screening itself, these offices provide valuable information to the public related to risk factors and early signs and symptoms. An informed public can engage in self-discovery, which has generated early stage finds in so many other cancers. In addition to the 1,000's of private dental offices who will join with OCF this April, a coalition of professional organizations, private sectors companies, and educational institutions have chosen to partner with us. The professional organizations include; The American Academy of Oral Medicine (AAOM), The American Academy of Periodontology (AAP), The American Dental Hygienists Association (ADHA), The American Association of Oral and Maxillofacial Surgeons (AAOMS), The Academy of General Dentistry (AGD), The American Dental Association (ADA), The American Academy of Oral & Maxillofacial Pathology (AAOMP), and The Canadian Dental Hygiene Association (CDHA).  Our [...]

2015-04-09T10:53:10-07:00April, 2015|OCF In The News, Oral Cancer News|

A Pastime Baseball Can Do Without

 Source:http://www.wsj.com Author: Larry Thornberry  The Major League Baseball season starts Monday, with many a pinch of tobacco between many a cheek and gum. Not everyone is happy about this (about the chewing tobacco, that is). The San Francisco board of supervisors is considering a measure to put chew off-limits at every ball field in the city, including AT&T Park, where the world-champion Giants play. A bill introduced February in the California Assembly would do the same in pro and league venues across the whole state. Major League Baseball supports this approach, since it cannot get the powerful players union on board with a chewing-tobacco ban. No word on how the laws would be enforced, but the sponsor of the state bill says don’t expect chew cops in dugouts or snuff-sniffing dogs in stands. Until relatively recently, tobacco around baseball clubhouses wasn’t considered much to worry about. As a young fan in the 1950s, I was used to players like Nellie Fox and Bill Tuttle, who stuffed so much chaw in their cheeks that they appeared to be trying to swallow a softball. One of my favorite players of the day, Rocky Bridges, looked like a chipmunk with a buzzcut. Baseball cards, an obsession with preteen boys for the better part of the last century, first came with packs of cigarettes, only later with bubble gum. Back in the day, sportswriters weren’t quick to link tobacco and the early deaths of former ballplayers. It was obvious in the case of Bill Tuttle, who died of mouth cancer at [...]

2015-04-09T10:45:16-07:00April, 2015|Oral Cancer News|

Young supports Oral Cancer Awareness with launch of new Burgundy Disposable Prophy Angle

Source: http://www.dentistryiq.comAuthor: DentistryIQ Editors Screening is the beginning of the end of oral cancer, and Young is joining the Oral Cancer Foundation in empowering hygienists to “Be Part of the Change.” Hygienists are on the front lines of oral cancer detection, and their involvement in early screening is paramount in the fight against oral cancer. Young is helping to support hygienists and keep oral cancer awareness in the forefront by launching the new Classic Burgundy Petite Web disposable prophy angle just in time for Oral Cancer Awareness Month in April. In addition to being the signature burgundy color of oral cancer awareness, the Classic Burgundy Petite Web disposable prophy angle packaging acts as a billboard to promote awareness through early detection. According to the Oral Cancer Foundation, more than 43,000 people are diagnosed with oral cancer in the U.S. each year, and only 57% will survive past five years due to late diagnosis. When found at early stages of development, oral cancer victims have an 80 to 90% survival rate. Thanks to engagement from the RDH community, we are on the cusp of a major change in this paradigm. With a commitment to screening for oral cancer warning signs during routine prophylaxis procedures, hygienists are helping to save lives through early detection. “Just doing ‘opportunistic’ cancer screenings during routine dental hygiene procedures would yield tens of thousands of opportunities to catch oral cancer in its early stages. One of our goals is to initiate an effort within the dental community to aggressively screen all [...]

2015-03-31T16:12:30-07:00March, 2015|OCF In The News, Oral Cancer News|
Go to Top