Oral Cancer News – Page 200

After a long battle with 3 different types of cancer, a footloose Orlando man takes on a 2,650-mile hike

At 68, John Casterline has beaten advanced-stage lung cancer, prostate cancer and throat cancer. Last month, he finished radiation treatments. Just one week ago, his doctors pronounced him cancer-free. So what is he doing to celebrate? Forget Disney World. Starting April 28, this Orlando retiree will be hiking 2,650 miles, from Canada to Mexico, along the Pacific Crest Trail — a route that will climb above 13,000 feet elevation and require him to average 20 miles a day. "I expect that I will experience weather that is too cold, too hot, too wet, too dry and too perfect," he wrote in his journal a year ago, when he began training seriously for the hike. "I will encounter rattle snakes, bears, and maybe even mountain lions. … The mosquitoes will be horrendous at times, the hills steep, the rocks sharp, the trail blocked, the wind very strong. [Sleep will be] occasionally fitful and I'll be carrying a backpack with 30-plus pounds." But if you have to ask why he's doing it, he wrote, you wouldn't understand. It is not simply that he hopes to raise $26,500 for the dramatically underfunded battle against lung cancer, a disease expected to claim the lives of 160,000 Americans this year — more than colon, breast and prostate cancers combined. Nor is it about creating some kind of legacy. Though followers can read his ongoing exploits on lungcancerhike.org, the website is intended to give fellow cancer survivors hope — and to collect donations for the American [...]

Oral Cancer Foundation News Team - A2011-04-21T13:49:22-07:00April, 2011|Oral Cancer News|

Blueberries contain vital polyphenols that could contribute to a decline in obestiy

Source: Medical News Today Last week it was reported that strawberries may help treat throat cancer, now a new study shows how blueberries may aid in curbing obesity. Plant polyphenols have been shown to fight adipogenesis, which is the development of fat cell, and induce lipolysis, which is the breakdown of lipids and fat. The study was done to evaluate whether blueberry polyphenols play a role in adipocyte differentiation, the process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. Polyphenols occur in all plant foods and contribute to the beneficial health effects of vegetables and fruit. Their contribution to the antioxidant capacity of the human diet is much larger than that of vitamins. The total intake in a person's diet could amount to 1 gram a day, whereas combined intakes of beta-carotene, vitamin C, and vitamin E from food most often is about 100 mg a day. Phenolic acids account for about one third of the total intake of polyphenols in our diet, and flavonoids account for the remaining two thirds. Flavonoids are further subdivided into several categories. Shiwani Moghe, a graduate student at Texas Woman's University said: "The promise is there for blueberries to help reduce adipose tissue from forming in the body I wanted to see if using blueberry polyphenols could inhibit obesity at a molecular stage. We still need to test this dose in humans, to make sure there are [...]

Oral Cancer Foundation News Team - A2011-04-21T13:48:47-07:00April, 2011|Oral Cancer News|

American Dental Association encourages public to get screened for oral cancer

Source: www.prnewswire.com Author: press release The American Dental Association (ADA) and the Oral Cancer Foundation (OCF) encourage people to take part in Oral Cancer Awareness Month in April by visiting a dentist for a free oral cancer screening. So far, more than 1,250 sites across the nation have registered their screening events with the OCF. "Although many dentists perform oral cancer screenings as a routine part of dental examinations, the ADA encourages dentists to go out into their communities during the week of April 11-15 to provide free oral cancer screenings to people who might not regularly visit a dentist," said ADA Spokesperson Sol Silverman, D.D.S., a professor of oral medicine at the University of California, San Francisco. "Early detection is critical in increasing survival rates for patients who have developed an oral cancer; and recognizing and managing precancerous lesions is extremely important in prevention," he said. Mr. Brian Hill, OCF executive director and an oral cancer survivor, also stressed the importance of early detection and the important role that dentists play. "Early detection is important because it reduces treatment-related morbidity and improves survival rates," he said. In 2010, the National Cancer Institute estimated that approximately 36,540 people were diagnosed with oral cancer and approximately 7,880 people died of oral cancer. The National Institute of Dental and Craniofacial Research (NIDCR) estimates that the five-year survival rate for people diagnosed early, when the disease has not spread beyond the original location, is approximately 83 percent compared to a 20 percent survival [...]

Oral Cancer Foundation News Team - A2011-04-11T20:25:42-07:00April, 2011|OCF In The News, Oral Cancer News|

Oral cancer: How discovery devices assist screenings

Source: www.dentistryiq.com Author: Nick Efthimiadis, Vice President, Sales & Marketing, LED Dental Inc. As the intense media attention surrounding Michael Douglas’s illness clearly demonstrated, oral cancer is increasingly in the news these days. With the unfortunate growth in the number of relatively young people contracting the disease due to exposure to the sexually-transmitted human papilla virus — specifically, the HPV-16 strain — oral cancer will only become a bigger concern for both patients and dental practices over time. In fact, the Oral Cancer Foundation recently announced that HPV-16 has now replaced tobacco as the leading cause of this disease. Sadly, one North American dies every hour of every day from oral cancer, and many of those who survive the disease are forced to deal with lengthy, painful treatment and permanent disfigurement. The main problem is that oral cancer is typically discovered in late stages, when the five-year survival rate is only around 30%. The good news: when discovered early, the survival rate leaps to 80%-to-90%. The key to early discovery is the dental practice. Ideally, each and every practice should be conducting a two-step oral cancer screening on all adult patients as part of their annual or semi-annual hygiene checkup. The first step consists of a conventional “white light” exam comprising visual inspection and palpation. The second step consists of examination with an adjunctive screening device. Fortunately, the two steps should take no more than five minutes combined. For the past several years, the adjunctive device that has [...]

Oral Cancer Foundation News Team - A2011-04-10T17:42:46-07:00April, 2011|Oral Cancer News|

Alcohol linked to 10% of cancer cases, study finds

Source: www.irishtimes.com Author: Dr. Muiris Houston Reducing alcohol intake would reduce the number of cancer cases in the Republic, the Irish Cancer Society has said. It was responding to the results of a major European study, published online by the British Medical Journal, which found that up to one in 10 cancers in men and one in 33 in women could be caused by drinking. Researchers concluded that drinking above recommended alcohol limits was likely to be responsible for the majority of cancer cases linked to alcohol, although for some people even a small consumption may increase the risk. They analysed data from eight European countries, involving more than 360,000 men and women who were aged between 35 and 70 at the beginning of the study. The research is part of the European Prospective Investigation of Cancer, one of the largest ever studies into the links between diet and cancer. Some 17 per cent of bowel cancers in men were linked to drinking, as were 4 per cent of cases in women. And 5 per cent of cases of breast cancer in women were also linked to drinking, the study showed. Overall, more than 18 per cent of cancers in men were down to drinking more than 24g of alcohol a day. In women, 4 per cent of cancers were due to drinking more than 12g of alcohol daily. Naomi Allen, from Oxford University, one of the researchers, said: “This research supports existing evidence that alcohol causes cancer and that [...]

Oral Cancer Foundation News Team - A2011-04-10T17:30:05-07:00April, 2011|Oral Cancer News|

Oral tongue squamous cell carcinoma is on the rise in young caucasian females, age 18 to 44 years

Source: Journal of Clinical Oncology Abstract Purpose To evaluate the incidence of oral cavity squamous cell carcinoma (OCSCC) and oral tongue squamous cell carcinoma (OTSCC) in young white women, age 18 to 44 years. Patients and Methods We analyzed incidence and survival data from the Surveillance, Epidemiology and End Results (SEER) Program of the National Cancer Institute from 1975 to 2007 for OCSCC and OTSCC. Three cohorts were examined: all ages, age 18 to 44 years (ie, “young”), and age > 44 years. Individuals were stratified by sex and/or race. Percentage change (PC) and annual percentage change (APC) were calculated. Joinpoint regression analyses were performed to examine trend differences. Results Overall, incidence of OCSCC was decreasing for all ages. However, incidence was increasing for young white women (PC, 34.8; APC, 2.2; P < .05). Incidence of OTSCC was decreasing for all ages except in the age 18 to 44 years group (PC, 28.8; APC, 1.8; P < .05). Young white individuals had increasing incidence trends of OTSCC (white women: PC, 111.3; APC, 4; P < .05; young white men: PC, 43.7; APC, 1.6; P < .05). The APC of OTSCC was significantly greater in young white women compared with that in young white men (P = .007). Furthermore, incidence of SCC in all other subsites of the oral cavity was decreasing. Nonwhites had a decreasing incidence of OCSCC and OTSCC. Cause-specific survival was similar among whites age 18 to 44 and individuals older than age 44 years. Conclusion OTSCC [...]

Charlotte Parker2011-04-10T17:26:36-07:00April, 2011|Oral Cancer News|

Dental professionals join The Oral Cancer Foundation to raise awareness as HPV is now the primary cause of Oral Cancers in America

NEWPORT BEACH, Calif., April 4, 2011 /PRNewswire/ -- A serious change in the cause of oral cancer is taking place nationally, and its implications are impacting the American public in a manner that a decade ago no one would have predicted. For decades, oral cancer (also known as mouth cancer, tongue cancer, tonsil cancer, and throat cancer) has been a disease which most often occurred in older individuals, who during their lifetimes had been tobacco users. Most cases were ultimately the result of lifestyle choices. Today that paradigm has changed. A common, sexually transferred virus has replaced tobacco as the number one cause of oral cancers, Human Papilloma Virus number 16 (HPV16). This is one of the same viruses that are responsible for the majority of cervical cancers in women. This year alone, approximately 37,000 Americans will be newly diagnosed with oral cancer, and one person will die every hour of every day from this disease. HPV16, one of about 130 versions of the virus, is now the leading cause of oral cancer, and is found in about 60% of newly diagnosed patients. Dr. Maura Gillison from the James Cancer Center, a long time researcher of the relationship between HPV and oral cancers, recently reported these new findings at the American Academy for the Advancement of Science meeting. This change in etiology, which has accelerated its influence over the last two decades as tobacco use in the US simultaneously was declining, has also changed the demographics of who is getting [...]

Charlotte Parker2011-04-07T10:39:32-07:00April, 2011|OCF In The News, Oral Cancer News|

Patient who loses jaw to oral cancer from smoking tells her story

Source: Los Angeles Times By: Milton D. Carrero, The Morning Call Look at Christine Brader's deep, amber eyes and you will see her beauty. Look beyond her contorted lips, and the jaw she lost as a three-time oral cancer survivor. Radiation took away her teeth, but she smiles. "I still feel like I've lost a great deal, she says, "but I'm still alive. And as long as I am alive, I am going to do what I can to help other people." Brader, 48, is sharing her face, her story and her time to tell the world about the dangers of smoking. The South Whitehall woman, who smoked about half-a-pack a day for 28 years, is featured in the national Truth campaign. Sponsored by the American Legacy Foundation, the series of ads present the unsweetened reality of those living with a serious illness caused by smoking. Brader's life is testament of resilience against oral cancer — a disease that, in five years, kills more than half of the 37,000 Americans diagnosed with it yearly, according to the Oral Cancer Foundation. "I still may not make it," she says, "and I don't have another chance in me. If I get it again, I'm done." Brader's life seemed idyllic until she discovered she had cancer. She had a stable job, a beautiful house in the woods and two teenage children who inspired her. But in 2007, she went to her family doctor, believing that she had a sinus infection. Her situation [...]

Charlotte Parker2017-03-29T19:08:10-07:00April, 2011|OCF In The News, Oral Cancer News|

Longitudinal study of human papillomavirus persistence and cervical intraepithelial neoplasia grade 2/3: critical role of duration of infection

Journal of the National Cancer Institute, April 5, 2011. Authors: Ana Cecilia Rodríguez, Mark Schiffman, Rolando Herrero, Allan Hildesheim, Concepción Bratti, Mark E. Sherman, Diane Solomon, Diego Guillén, Mario Alfaro, Jorge Morales, Martha Hutchinson, Hormuzd Katki, Li Cheung, Sholom Wacholder, Robert D. Burk Background The natural history of human papillomavirus (HPV) infections in older women is critical for preventive strategies, including vaccination and screening intervals, but is poorly understood. In a 7-year population-based cohort study in Guanacaste, Costa Rica, we examined whether women’s age and the duration of carcinogenic HPV infections influenced subsequent persistence of infection and risk of cervical intraepithelial neoplasia grade 2 (CIN 2) or worse disease. Methods At enrollment, of the 9466 participants eligible for pelvic examination, 9175 were screened for cervical neoplasia using multiple methods; those with CIN 2 or worse disease were censored and treated. Participants at low risk of CIN 2 or worse (n = 6029) were rescreened at 5–7 years (passively followed), whereas higher-risk participants (n = 2115) and subsets of low-risk women (n = 540) and initially sexually inactive women (n = 410) were rescreened annually or semiannually (actively followed) for up to 7 years. HPV testing was done using a polymerase chain reaction–based method. We determined, by four age groups (18–25, 26–33, 34–41, and ≥42 years), the proportion of prevalent infections (found at baseline) and newly detected infections (first found during follow-up) that persisted at successive 1-year time points and calculated absolute risks of CIN 2 and CIN grade 3 (CIN [...]

Charlotte Parker2011-04-10T17:25:47-07:00April, 2011|Oral Cancer News|

HPV link comes as a shock to male cancer patients

By ANIKA CLARK Stanley Sikora of Fall River and Tom Souza of Swansea clearly remember when they started their battles with cancer — life-changing moments while raking leaves or shaving, when they touched their necks and felt a lump. It's a common experience thanks to a disease that, between the suffering of friends, families and ourselves, has become nearly universal. But then came news neither expected. Tumors from both men tested positive for human papillomavirus, an often sexually transmitted virus that is increasingly being linked to cancers of the head and neck. At Massachusetts General Hospital's Center for Head and Neck Cancers, "it's something that we see practically on a daily basis," said Dr. Lori Wirth, medical director for head and neck oncology, who said in an email that, although there are not-fully-understood co-factors, there's strong data that about 60-65 percent of all cancers of the oropharynx (the rear of the mouth, including the back of the throat, tonsils and the base of the tongue) are HPV-related. "Our awareness that HPV is associated with oropharynx cancers is something that has been emerging over the last 5-10 years," she said. "Ten years ago, we didn't even look for (it)." Upon learning of his HPV diagnosis, "I honestly felt creepy about myself," said Sikora, 59, albeit somewhat reassured when he found out how easily it's transmitted. "Already I was shocked that I got cancer. Now it's from HPV," he said. "So I'm thinking 'I can't be going around telling people I got [...]

Oral Cancer Foundation News Team - A2011-04-04T14:41:03-07:00April, 2011|Oral Cancer News|