Oral Cancer News

Oncologists Favor Psychosocial Care, But Give It Short Shrift

Source: Oncology STAT MIAMI (EGMN) - Oncologists endorse the idea of connecting cancer patients to psychosocial care at the conclusion of active treatment. But practice doesn't align with beliefs, perhaps because they are unfamiliar with where to refer their patients for care. Among 57 oncologists who responded to a survey in the southeastern United States, 35, or 61%, considered psychosocial care to be beneficial. A majority thought it was "important" following cancer treatment, reported Laurie Freeman-Gibb at the annual conference of the American Psychosocial Oncology Society (APOS). But the oncologists said they spent just 4.2 minutes, on average, discussing psychosocial care during consultations, according to Ms. Freeman-Gibb, a lecturer in the department of nursing at the University of Windsor in Ontario, and her colleague Andrew Hatchett, Ph.D., of the University of Louisiana at Lafayette's department of kinesiology. And since only about 1 in 6 oncologists responded to the survey - it was sent to 350 practitioners - the findings may present an overly optimistic picture of what happens in real-life practice when a patient leaves active treatment and returns to the community for care. "I think it's sometimes a time constraint," said Ms. Freeman-Gibb. "If you only have 20 minutes to see this person and you open the floodgates to what's really going on, you might never get out the door ... especially if you don't know whom to tell the patient to call." Dr. Hatchett said the impetus for the study was a series of conversations he had with [...]

Charlotte Parker2012-05-02T10:45:02-07:00May, 2012|Oral Cancer News|

Genes May Link Disparate Diseases

Source: The Wall Street Journal Diseases that strike different parts of the body—and that don't seem to resemble each other at all—may actually have a lot in common. Scientists have identified the genetic basis for many separate diseases. Now, some researchers are looking at how the genes interact with each other. They are finding that a genetic abnormality behind one illness may also cause other, seemingly unrelated disorders. Sometimes diseases are tangentially linked, having just one gene in common. But the greater the number of shared genetic underpinnings a group of diseases has, the greater the likelihood a patient with one of the illnesses will contract another. Researchers have found evidence, for example, that there is a close genetic relationship between Crohn's disease, a gastrointestinal condition, and Type 2 diabetes, despite the fact the two conditions affect the body in very distinct ways. Other illnesses with apparently close genetic links are rheumatoid arthritis and Type 1 diabetes, the form of the disease that usually starts in childhood, says Joseph Loscalzo, chairman of the department of medicine at Brigham and Women's Hospital in Boston. This network approach, known among scientists as systems biology, could change the way medical specialists view and treat disease, according to some researchers. Rather than only looking to repair the parts of the body that are directly affected by illness, "we should be looking at what the wiring diagram [inside of cells] looks like," says Albert-László Barabási, a physicist at Northeastern University's Center for Complex Network Research [...]

Charlotte Parker2012-05-02T10:33:24-07:00May, 2012|Oral Cancer News|

$27 Million Verdict Against R.J. Reynolds for Cancer Victim

Source: JDsupra.com A Florida man was awarded $27 million in compensatory and punitive damages against tobacco company R.J. Reynolds last month after doctors told him that 44 years of smoking caused his lung cancer. Plaintiff had lung removed due to cigarette addiction Thousands of lawsuits pending against big tobacco companies First payouts by big tobacco expected to be made today Addictive Habits Emmon Smith, a minister in Mariana, Florida, started smoking when he was a 13-year-old boy in 1944. Despite numerous attempts to quit, he couldn’t kick the addictive habit until he was forced to in 1992 by a cancer diagnosis and subsequent removal of one of his lungs. Smith sued tobacco company R.J. Reynolds in 2008, and in March of this year a jury awarded him $10 million in compensatory damages and $20 million in punitive damages; however, they found the plaintiff 30 percent at fault so he will receive only $7 million of the compensatory award, for a total of $27 million. Smith’s suit was led by attorney Richard Diaz as well as a team of attorneys from Crabtree & Associates and Ratzan Law Group. The Smith case was just one of more than 8,000 lawsuits against tobacco companies stemming from a 1990s class action known as the Engle case. In 2000, a Florida jury awarded class members a stunning $145 billion in punitive damages, finding that cigarettes are dangerous, addictive, carcinogenic, and most importantly, that tobacco companies knew all this and lied about it. “They found that [...]

Charlotte Parker2012-05-01T10:35:58-07:00May, 2012|Oral Cancer News|

Robotic Surgery Is Useful Option for Oral Cancer

Source: Onclive.com Minimally invasive transoral robotic surgery (TORS), used alone or combined with adjuvant therapy, provides good functional and oncologic outcomes in patients with oropharyngeal squamous cell carcinoma (OPSCC), new research suggests. The results were especially impressive in patients with human papillomavirus (HPV) infection, which is currently the most common cause of OPSCC in Europe and the United States. Eric J. Moore, MD, associate professor of Otolaryngology at the Mayo Clinic in Rochester, Minnesota, and coauthors reviewed a prospective database of patients with previously untreated OPSCC arising in the tonsil or base of the tongue who underwent TORS at their institution during a recent 2-year period. In 2011, about 12,000 individuals in the United States were diagnosed with OPSCC, according to the authors. The most common sites are the tonsillar fossa and base of the tongue. Customarily, OPSCC has been treated with combined modality therapy, including open surgical resection through mandibulotomy, neck dissection, and adjuvant radiation therapy or combined chemotherapy and radiation therapy. TORS was later introduced to improve access to these tumors. Functional outcomes of the study included gastrostomy tube dependence and tracheostomy dependence. Oncologic outcomes included local, regional, and distant control and disease-specific and recurrence-free survival. Overall, 66 patients who underwent TORS as their primary treatment were followed for a minimum of 2 years. Sixty-four patients, or 97%, were able to tolerate an oral diet and maintain their nutritional needs before initiating adjuvant therapy at 4 weeks. Only 3 patients, or 4.5%, required long-term gastrostomy tube use, and [...]

Charlotte Parker2012-04-30T17:14:50-07:00April, 2012|Oral Cancer News|

Exercise helps cancer patients

Source: www.dailyrx.com Author: staff A small trial shows that rehabilitation therapy for head and neck cancer patients clearly improves their ability to swallow faster, something that's often damaged with the cancer treatment. Intense treatment for cancers of the head and neck often involves both chemotherapy and radiation. With many important muscles involved in the region, preventing the areas targeted by radiation from weakening can be avoided with swallowing exercises. The study compared a control group given no swallowing exercises to another group given the series of targeted rehabilitation therapy. It took nine months for the two groups to have equivalent ability, highlighting the importance of preserving muscle function prior to cancer treatment. Importantly, rehabilitation after cancer treatment can prevent some of the worst side effects, and allows patients to get back to their normal day to day life. The initial damage from cancer treatment was extensive, as both groups had equal ability immediately after cancer therapy. Yet the muscle function rebounded quickly in the rehabilitation group, as results at 3 and 6 months after treatment were improved as a result of the swallowing exercises. The group given exercises also rated themselves as more comfortable eating in public, an important qualifier in showing how well the exercises worked. "With improvements in swallowing function from post-treatment exercises, interest in the use of prophylactic swallowing exercises to prevent or minimize post-CRT swallowing dysfunction has grown" the authors write as background in the study. "Indeed, some cancer treatment centers recommend prophylactic swallowing exercises for [...]

Oral Cancer Foundation News Team - A2012-04-30T12:28:50-07:00April, 2012|Oral Cancer News|

New technique to synthesize boron-nitride nanotubes

Source: www.azom.com Author: Cameron Chai Researchers at the Institute of Life Sciences, Scuola Superiore Sant'Anna in Pisa, Italy have used boron-nitride nanotubes (BNNT) to improve the effectiveness of the cancer treatment. Irreversible Electroporation involves putting holes in tumor cell walls. It is used to treat soft tissue tumors in cancers that are difficult to treat, such as head and neck, prostate, pancreas, kidney, lung and liver. The treatment is being offered and studied for effectiveness at many centers in the USA. Researchers belonging to the Department of Energy's Thomas Jefferson National Accelerator Facility, the National Institute of Aerospace and NASA's Langley Research Center provided the BNNTs. A hole of an appropriate size in a cancer cell wall may cause the cell to commit suicide. The chief scientist at BNNT, Michael W. Smith, offered BNNTs to the researchers in Italy. These high-quality BNNTs are flexible, long, and have a small diameter. They are crystalline and have minimal defects. The BNNTs were suspended in glycol-chitosan and then chopped into bits with sound waves. These bits were then put on human epithelial carcinoma (HeLa) cells. The amount of BNNTs that had the capacity to kill around 25% of the cancerous cells within a period of 24 hours was determined. Through an electroporation device, the researchers supplied electricity of 160 V to a solution which contained the particular amount of BNNTs. The HeLa cells were exposed to the solution. Further, unexposed cancer cells were also treated with the same amount of voltage. When the [...]

Oral Cancer Foundation News Team - A2012-04-30T12:24:11-07:00April, 2012|Oral Cancer News|

Survey reveals most are unaware of the causes and symptoms of mouth cancer

Source: www.cosmeticdentistryguide.co.uk Author: staff A survey has revealed that most people are unaware of the major risk factors and symptoms of oral cancer. The SimplyHealth Annual Dental Health Survey revealed that of the 11,785 adults surveyed, 70 percent were unaware of the symptoms of mouth cancer while only 3 percent knew that kissing could increase your risk of moth cancer as a result of exposure to the human papilloma virus (HPV). A spokesperson for SimplyHealth said that most were aware that smoking and drinking increased the risk of oral cancer, but very few people were aware of the link between oral cancer and the HPV, a virus which is also responsible for some cases of cervical cancer. According to Cancer Research UK, some strains of HPV increase the risk of mouth cancer, which could explain why the disease is becoming more common in young people, as the virus is spread through physical contact. Dentist Michael Thomas said that it was important for people to be aware of the symptoms of mouth cancer, as well as the causes. As with most forms of cancer, the earlier mouth cancer is diagnosed, the higher the chance of survival. Only 28 percent of adults surveyed had discussed mouth cancer with their dentist and this is worrying, as dentists are in a prime position to spot the early warning signs and arrange further tests and treatment. The most common symptoms of mouth cancer include lumps or swellings in the mouth or throat, sores or ulcers [...]

Oral Cancer Foundation News Team - A2012-04-30T12:19:01-07:00April, 2012|Oral Cancer News|

Handheld probe shows promise for oral cancer detection

Source: phys.org Author: staff A team of American researchers have created a portable, miniature microscope in the hope of reducing the time taken to diagnose oral cancer. The probe, which is around 20 cm long and 1 cm wide at its tip, could be used by doctors to diagnose oral cancer in real-time or as a surgical guidance tool; dentists could also use it to screen for early-stage cancer cells. The probe has been presented today in IOP Publishing's Journal of Micromechanics and Microengineering, and has shown good agreement with images of oral cancers obtained using conventional, much slower techniques at the University of Texas Health Science Centre at San Antonio, TX. Historically, the death rate associated with oral cancer is particularly high; not because it is hard to discover or diagnose, but due to the cancer being routinely discovered late in its development. Lead author of the study Dr John X J Zhang at the University of Texas at Austin said: "Today, that statement is still true, as there isn't a comprehensive programme in the US to opportunistically screen for the disease; without that, late stage discovery is more common." The probe uses a laser to illuminate areas of the sample and can view beneath the surface of tissue, creating full 3D images. It can also take a series of images and layer them on top of each other, much like the tiling of a mosaic, giving a large overall field-of-view. The key component of the probe is [...]

Oral Cancer Foundation News Team - A2012-04-27T13:56:25-07:00April, 2012|Oral Cancer News|

It’s Time to Stop Letting Congress Stomp on Nonprofit Advocacy Rights

Source: The Chronicle of Philanthropy Nonprofit organizations have fewer rights to speak out about important public-policy matters today than they did last year. The latest assault on advocacy came in a spending bill Congress approved to provide money to education, health, and human-service groups. These new restrictions on advocacy were passed as part of a coordinated campaign by conservatives to quash popular democracy. Unfortunately, as contrasted with past “defund the left” efforts, charity leaders didn’t find out about them in time to take action to prevent their passage. The challenges to nonprofit advocacy began more than three decades ago when the Heritage Foundation started making new restrictions a priority. This attack was pushed by the Reagan White House in the early 1980s, took the form of major Republican congressional legislative efforts in the mid-1990s, and has arisen in various forms since then. Some conservative lawmakers and Republican White House officials have tried to go so far as to limit what charities can do with private contributions; others have tried to restrict the types of activities that nonprofits can conduct with federal funds. Most of their efforts were stopped by groups whose missions were to serve as watchdogs to protect charities’ rights and the coalitions they organized. Nevertheless, conservatives succeeded in several attempts to chip away at nonprofit advocacy rights. For example, Congress voted to prohibit social-welfare organizations classified under Section 501(c)(4) from receiving federal grants if they lobby. Additionally, grantees of the Legal Services Corporation face greater restrictions on advocacy [...]

Charlotte Parker2012-04-27T10:42:00-07:00April, 2012|Oral Cancer News|

Pig mucus effective at blocking viruses associated with cervical and oral cancer

Source: American Chemical Society Scientists are reporting that the mucus lining the stomachs of pigs could be a long-sought, abundant source of "mucins" being considered for use as broad-spectrum anti-viral agents to supplement baby formula and for use in personal hygiene and other consumer products to protect against a range of viral infections. Their study appears in ACS' journal Biomacromolecules. In the report, Katharina Ribbeck and colleagues point out that mucus, which coats the inside of the nose, mouth and vagina, is the immune system's first line of defense. The slimy secretion traps disease-causing microbes, ranging from influenza virus to HIV (which causes AIDS) before they can cause infection. That has led to consideration of mucin, the main component of mucus, for use as an anti-viral agent in a variety of products. However, existing sources of mucins, such as breast milk, cannot provide industrial-sized quantities. Large amounts of mucus exist in the lining of pigs' stomachs, and the authors set out to determine if pig mucus - already used as a component of artificial saliva to treat patients with "dry mouth," or xerostomia - has the same anti-viral activity. They found that pig mucus is effective at blocking a range of viruses, from strains of influenza to the human papilloma virus, which is associated with cervical and oral cancer. They report that pig mucins could be added to toothpastes, mouthwashes, wound ointments and genital lubricants to protect against viral infections. "We envision porcine gastric mucins to be promising antiviral components [...]

Charlotte Parker2012-04-26T17:17:40-07:00April, 2012|Oral Cancer News|