About Oral Cancer Foundation News Team - A

This author has not yet filled in any details.
So far Oral Cancer Foundation News Team - A has created 2444 blog entries.

Can even moderate drinking increase the risk of cancer?

Source: www.theguardian.com Author: Luisa Dillner Alcohol may be a social lubricant but WHO and Public Health England say it can cause cancer. Last week the alcohol industry was accused of downplaying the link between alcohol and the increased risk of seven cancers: mouth, throat, oesophagus, liver, breast and colon. A research paper in Drug and Alcohol Review found that “responsible drinking” information funded by the alcohol industry tends to push the message that only heavy drinking increases the risk of these cancers. But the paper says the risk starts with low levels of drinking, even though the risk itself is low. So is the recommended number of alcohol units a week – 14 – too high? The solution Even less than 1.5 units a day – a small glass of wine – can increase the risk of mouth, throat, oesophagus and breast cancer (in women), according to a UK government committee. While the toll of heavy drinking on the liver and pancreas is well known, the link to cancers, especially breast and colorectal, is less so. There are more than 100 epidemiology studies showing an association between breast cancer and alcohol, the risk increasing with less than one daily glass of wine. Research at Harvard found that while light to moderate drinking was not significantly associated with an increased risk for men (unless they smoked), it did increase the risk of breast cancer for women. Edward L Giovannucci, professor of nutrition and epidemiology at Harvard School of Public Health and [...]

2017-10-02T10:30:20-07:00October, 2017|Oral Cancer News|
Read More

HPV and cancer: Key mechanism may suggest treatment

Source: www.medicalnewstoday.com Author: Maria Cohut New research from Georgetown University in Washington, D.C., investigates how the human papillomavirus promotes cancer. The findings might point to a potential new and improved strategy for targeted treatment. The human papillomavirus (HPV) refers to a group of viruses transmitted through sexual contact. Some types of HPV cause various kinds of cancer, including mouth, anus, and cervical cancer. According to data from the Centres for Disease Control and Prevention (CDC), around 1 in 4 people in the United States are infected with HPV. Although treatments for HPV-related conditions do exist, they either target non-cancerous outcomes (such as genital warts) or they focus on the prevention of cancer through screening of abnormal cell activity. Treatments for cancers caused by HPV include surgical interventions and chemotherapy, but at present, none of the options specifically address the viral source. Researchers from Georgetown University Medical Center in Washington, D.C., have now identified the mechanism that promotes the survival of cancerous cells due to HPV. The study, which was led by Dr. Xuefeng Liu, describes a molecular apparatus that renders cancer cells "immortal." Understanding how this apparatus works may lead to better targeted treatments in the future, the researcher suggests. "There is no targeted treatment now for these cancers since German virologist Harald zur Hausen, Ph.D., discovered in 1983 that HPV can cause cervical cancer," says Dr. Liu. "Recently," he adds, "the numbers of HPV-linked head and neck cancers have increased in the U.S. Now we have a chance to [...]

2017-10-02T10:24:34-07:00October, 2017|Oral Cancer News|
Read More

Halving radiation therapy for HPV-related throat cancer offers fewer side effects, similar outcomes

Source: www.eurekalert.org Author: Mayo Clinic press release Mayo Clinic researchers have found that a 50 percent reduction in the intensity and dose of radiation therapy for patients with HPV-related throat cancer reduced side effects with no loss in survival and no decrease in cure rates. Results of a phase II study were presented today at the 59th Annual Meeting of the American Society for Radiation Oncology in San Diego by Daniel Ma, M.D. a radiation oncologist at Mayo Clinic. "A common approach for treating HPV-related throat cancer is a combination of surgery followed by daily radiation therapy for six to 6½ weeks," says Dr. Ma. "However, the radiation treatment can cause a high degree of side effects, including altered taste, difficulty swallowing, dry mouth, stiff neck and damage to the jaw bone." Dr. Ma says that patients with HPV-related throat cancer tend to be young and, once treated, are likely to live a long time with possibly life-altering side effects from the standard treatment. "The goal of our trial was to see if an aggressive reduction of radiation therapy (two weeks of radiation twice daily) could maintain excellent cure rates, while significantly reducing posttreatment side effects, improving quality of life and lowering treatment costs." Researchers followed 80 patients with HPV-related oropharyngeal squamous cell cancer with no evidence of residual disease following surgery and a smoking history of 10 or fewer pack years. That's the number of years smoking multiplied by the average packs of cigarettes smoked per day. At two [...]

2017-09-26T07:17:21-07:00September, 2017|Oral Cancer News|
Read More

Alcohol industry ‘playing down’ risk of cancer by using tobacco industry tactics

Source: news.sky.com Author: Paul Kelso, Health Correspondent The alcohol industry is misleading the public by downplaying the risk of cancer through similar tactics to the tobacco industry, researchers say. Liquor bottles in grocery store A study led by the London School of Hygiene and Tropical Medicine (LSHTM) and Sweden's Karolinska Institutet found the industry is using "denying, distortion and distraction" strategies to minimise evidence. Researchers analysed information relating to cancer on the websites and documents of 28 alcohol industry organisations between September and December last year, finding that most showed "some sort of distortion or misrepresentation" of evidence. The industry most commonly presented the relationship between alcohol and cancer as highly complex, implying there was no evidence of a consistent or independent link, according to the study. Other tactics included denying that any relationship existed or claiming that there was no risk for light or moderate drinking, as well as presenting alcohol as just one risk among many. Alcohol consumption is an established risk factor for a range of cancers, including oral cavity, liver, breast and colorectal cancers, and accounts for about 4% of new cancer cases annually in the UK. The latest British government advice on alcohol, issued last year, makes an explicit link between cancer and alcohol. It states: "The risk of developing a range of health problems (including cancers of the mouth, throat and breast) increases the more you drink on a regular basis." During the consultation phase the alcohol industry challenged the link with cancer. [...]

2017-09-08T11:53:23-07:00September, 2017|Oral Cancer News|
Read More

What’s next after creating a cancer-prevention vaccine?

Source: www.scientificamerican.com Author: Dina Fine Maron A winner of this year’s Lasker Awards talks about his work with HPV Imagine a vaccine that protects against more than a half-dozen types of cancer—and has a decade of data and experience behind it. We have one. It’s the human papillomavirus (HPV) vaccine, and it was approved for the U.S. market back in June 2006. It can prevent almost all cervical cancers and protect against cancers of the mouth, throat and anus. It also combats the sexually transmitted genital warts that some forms of the virus can cause. On Wednesday, two researchers who completed fundamental work on these vaccines received one of this year’s prestigious Lasker Awards, a group of medical prizes sometimes called the “American Nobels.” Douglas Lowy and John Schiller, whose research provided the basis for the HPV vaccine, were selected alongside a researcher who separately unraveled key aspects of metabolic control of cell growth. Planned Parenthood was also given an award, for its public service. Lowy and Schiller, who both work at the U.S. National Cancer Institute (NCI), received the Lasker for their research on animal and human papillomaviruses—work that enabled the development of a vaccine against HPV-16 type, a form of the virus that fuels many HPV malignancies. The duo’s experiments proved that the vaccine is effective in animals, and they also conducted the first clinical trial of an HPV-16 vaccine in humans. That gave pharmaceutical companies the evidence they needed to invest in their own vaccines designed to [...]

2017-09-06T08:08:49-07:00September, 2017|Oral Cancer News|
Read More

Personalised cancer treatment

Source: medicalxpress.com Author: University of Oslo In Norway, more and more people are being affected by cancer of the mouth and throat. In recent years, the incidence has increased but the mortality has remained the same. Cisplatin is one of the most commonly administered cytostatics for this patient group. At the start of treatment, the drug works well. Gradually, though, most patients experience that the tumour develops resistance against this drug and the prognosis for survival then becomes very poor. In her PhD thesis, Jian Gao wanted to find out how the cancer cells could protect themselves against this cytostatic i.e. what is the underlying mechanism of resistance. She therefore cultured various cancer cell lines derived from oral cavity which were given differing doses of the cytostatic cisplatin. A cancer cell line is cultured from patients' cancerous tumours and can live indefinitely in the laboratory. These types of cell lines are used to examine the biology and the changes that have resulted in the development of cancer. Because the cancer cell lines divide in the laboratory, they can also adapt to new growth conditions, for example by becoming resistant to the cytostatic cisplatin in the same way as the cancer tissue in the patients. "First, I had to find those cancer cells that were sensitive to the cytostatic," explains Jian Gao. By identifying the sensitive cancer cell lines that I could make resistant in the laboratory, I could then study which changes took place in the cells as they changed [...]

2017-09-04T14:06:02-07:00September, 2017|Oral Cancer News|
Read More

HPV-related oral cancers have risen significantly in Canada

Source: www.ctvnews.ca Author: Sheryl Ubelacker, The Canadian Press The proportion of oral cancers caused by the human papillomavirus has risen significantly in Canada, say researchers, who suggest the infection is now behind an estimated three-quarters of all such malignancies. In a cross-Canada study, published Monday in the Canadian Medical Association Journal, the researchers found the incidence of HPV-related oropharyngeal cancers increased by about 50 per cent between 2000 and 2012. "It's a snapshot of looking at the disease burden and the time trend to see how the speed of the increase of this disease (is changing)," said co-author Sophie Huang, a research radiation therapist at Princess Margaret Cancer Centre in Toronto. Researchers looked at data from specialized cancer centres in British Columbia, Alberta, Ontario and Nova Scotia to determine rates of HPV-related tumours among 3,643 patients aged 18 years or older who had been diagnosed with squamous cell oropharyngeal cancer between 2000 and 2012. HPV is the most common sexually transmitted infection worldwide. Most people never develop symptoms and the infection resolves on its own within about two years. "In 2000, the proportion of throat cancer caused by HPV was estimated at 47 per cent," said Huang. "But in 2012, the proportion became 74 per cent ... about a 50 per cent increase." Statistics from a Canadian Cancer Society report last fall showed 1,335 Canadians were diagnosed in 2012 with HPV-related oropharyngeal cancer and 372 died from the disease. HPV is the most common sexually transmitted infection worldwide. Most people [...]

2017-08-14T12:10:46-07:00August, 2017|Oral Cancer News|
Read More

Transoral robotic surgery cuts patient recovery time

Source: exclusive.multibriefs.com Author: Carolina Pickens Oral cancer is diagnosed in almost 50,000 Americans each year and has a 57 percent survivability rate past five years, according to research from the Oral Cancer Foundation. 3D illustration of surgical robot The number of diagnoses has been fairly constant in oral and pharyngeal cancer for decades, but survivability has actually gone up slightly in the last 10 years. This can be attributed to the increasing percentage of patients with dental insurance attending annual appointments (when oral cancer is most often recognized and diagnosed earlier), the spread of HPV-related oral cancer (which is easier to treat) and advances in diagnostic tools for dentists and oral specialists. These advancements aren't limited to recognizing oral and throat cancer; strides in scientific approaches for surgical treatment are changing the way specialists treat oral phalangeal cancers. For example, Nepean Hospital of New South Wales has seen drastic improvement in patients' quality of life and surgical recovery time by performing transoral robotic surgery (TORS) with the da Vinci System. This technology provides surgeons the tools needed to perform successful, minimally-invasive surgeries for patients with T1 or T2 throat cancers. "Without the robot, tongue and throat cancers are among the most difficult tumors to surgically remove," said Dr. Chin, an otolaryngology, head and neck surgeon at the hospital. Previous surgical methods required surgeons cut into the neck to access tumors in the throat and back of the mouth — and operations would often last for up to 12 [...]

2017-07-30T14:52:05-07:00July, 2017|Oral Cancer News|
Read More

Calgary cancer patient asks why smokers are near hospitals if grounds are supposed to be ‘smoke-free’

Source: globalnews.ca Author: Heather Yourex-West At just 47-years-old, Tim Allsopp is battling throat cancer. He doesn’t smoke but during he’s his treatment, he says, he’s been exposed to second-hand cigarette smoke more often because he often passes by people smoking on his way to treatment at Calgary’s Tom Baker Cancer Centre. “Everyday when we come to therapy, we notice that there’s people smoking outside the building,” Allsopp said. “That’s confusing to me because the policy states, no smoking on Alberta Health Services property, this includes buildings, grounds and parking lots.” “I’m at the point now where I’m very susceptible to infection and that could land me in the emergency department in almost life threatening condition.” While AHS has had a smoke-free hospital grounds policy for years, it doesn’t take long to spot people lighting up. AHS says it tries to enforce its policy, but it’s not easy. WATCH: Smokers ignore no smoking signs in front of Winnipeg hospitals “Our protective services people try to use an educational approach first but if that’s not successful, then they have the power to issue a ticket,” said Dr. Brent Friesen, lead medical officer of health for Alberta Health Services’ tobacco reduction strategy. Friesen says the problem is that AHS can only issue tickets for people breaking either provincial law or city by-law, not AHS policy. That means, while AHS may say no smoking is allowed on hospital grounds, the province only requires people keep a five-metre distance from hospital doors. “If they’re further [...]

2017-07-25T08:35:20-07:00July, 2017|Oral Cancer News|
Read More

Head and neck cancer is more common than you think

Source: www.irishtimes.com Author: Jamie Ball Well over 1,000 people in Ireland are diagnosed each year with cancers of the head and neck, with almost three-quarters of cases being attributed to smoking and alcohol. Yet this pernicious form of cancer very often goes under-reported, or sufficient heed isn’t paid to the warning signs that, if caught early, may be the difference between life and death. This is why July 27th will mark the third World Head & Neck Cancer day, taking place across 53 countries. The 2017 National Cancer Strategy highlights the importance of prevention, detection and diagnosis, and education and awareness is key for early recognition of the disease. According to James Paul O’Neill, Prof of Otolaryngology, Head and Neck Surgery in Beaumont Hospital, Dublin and the Royal College of Surgeons in Ireland, there can be many different types of cancers within the head and neck, each with their own tissue characteristics and biological behaviour. “Cancers may develop in several areas of this region, including the mouth, throat, larynx (voice box), glandular tissue (thyroid), salivary tissue (parotid gland), lymphatic tissue, nose, sinuses and skin. Patients have a large variety of symptoms and signs according to the subsite of the disease,” says O’Neill. He says surgery incorporates many different techniques and skills, as the region has essential functional roles, such as talking, breathing, smelling, hearing, chewing and swallowing. “We are now in the age of highly-specialised technological innovations. There is a drive towards minimally invasive surgery because we can perform the [...]

2017-07-25T08:28:00-07:00July, 2017|Oral Cancer News|
Read More
© - The Oral Cancer Foundation - Head & Neck Cancer IRS 501(c)3 Charity - 3419 Via Lido #205, Newport Beach, CA 92663 | Disclaimer / Privacy Policy
Go to Top