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Robotic surgery breakthrough helping Valley throat and mouth cancer patients

Source: www.abc15.com Author: Jodie Heisner A breakthrough surgery helping those with mouth and throat cancer is being offered by a surgeon right here in the Valley (Mesa, AZ). “It’s nice when about every few years something comes along that’s really a giant step,” said Dr. Glen Rothman of Banner Desert Medical Center. That giant step is being taken with small robotic arms and 3-D imaging. The procedure is done without the doctor even touching you. “Truly the ability to go through the mouth where my hands and my eyes cannot see, with tiny instrumentation and remove tumors in ways that really just did not exist before this technology,” said Dr. Rothman. The procedure is helping patients with mouth and throat cancers similar to the type Michael Douglas is fighting. “It is my understanding that he has squamous cell cancer of his tongue base and that is one of the areas where the daVinci robot could really be used,” said Dr. Rothman. Douglas has opted for chemotherapy and radiation to treat the disease, but for those that choose the surgery with the daVinci robot there are benefits. Without the robot the surgery involves cutting through the jaw leaving scarring. Typically patients are in the hospital for at least eight days. “We do it though the mouth with no incisions on the outside. Just a couple days in the hospital, none of those tubes, no external scars and a much faster, easier recovery,” said Dr. Rothman. It also helps to eliminate many [...]

2010-09-21T12:34:10-07:00September, 2010|Oral Cancer News|
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Smokeless tobacco won’t help smokers quit

Source: www.webmd.com Author: Bill Hendrick Smokeless tobacco products -- whether chewed or used as dry or moist snuff -- may increase the risk of heart attack, fatal stroke and certain cancers, says a new policy statement published online in Circulation: Journal of the American Heart Association. "No tobacco product is safe to consume," Mariann Piano, PhD, lead writer of the policy statement and a professor in the department of behavioral health science at the University of Illinois at Chicago, says in a news release. The notion that smokeless tobacco may help reduce the rate of cigarette smoking is based in part on Swedish research, which showed a significant decline in smoking by Swedish men between 1976 and 2002 that corresponded with an increase in the use of smokeless tobacco. But in similar research in the U.S., the opposite was found to be true, the article says. There was no reduction in smoking rates among people who used smokeless tobacco products. Nicotine-Replacement Therapy Piano says that smokers trying to kick the habit might want to try nicotine-replacement therapy, by chewing nicotine gum or using a nicotine patch that can be attached to the skin, rather than using smokeless tobacco products. Piano tells WebMD that most people who use nicotine-replacement therapy do so for short periods of time, and it doesn't appear to be as addictive as smokeless tobacco "because of slower absorption, lower doses of nicotine, greater cost, lack of flavoring, sociocultural influences" or a combination of such factors. She says [...]

2010-09-14T09:06:26-07:00September, 2010|Oral Cancer News|
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FDA sends e-cigarette companies a warning

Source: www.boston.com Author: staff The Food and Drug Administration is lighting a fire under the electronic cigarette industry to work with the agency to legally market the devices and is cautioning other companies that their sales and manufacturing practices violate federal law. The FDA said yesterday it sent warning letters to five companies that make e-cigarettes or components for the plastic and metal devices that heat a liquid nicotine solution in a disposable cartridge, creating vapor that the smoker inhales. In the letters, the FDA said the companies are violating the Federal Food, Drug and Cosmetic Act, including unsubstantiated claims and poor manufacturing practices. The FDA is asking the companies to let the agency know within 15 business days how it plans to correct the violations. The other companies receiving warning letters were E-CigaretteDirect LLC of Colorado, Ruyan America Inc. in Minneapolis, Gamucci America in Florida, and Johnson Creek Enterprises LLC of Wisconsin. But in a letter to the Electronic Cigarette Association, the FDA said the actions were not meant to be seen as a larger effort to ban e-cigs. It urged the industry group to work with the FDA to ensure the safety and effectiveness of the devices to help people quit smoking traditional cigarettes through usually expensive clinical trials. “We are interested in finding out whether e-cigarettes can be proven safe and effective,’’ said Michael Levy, FDA compliance lawyer.

2010-09-13T09:02:45-07:00September, 2010|Oral Cancer News|
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U.S. smoking rate hasn’t changed, CDC says

Source: www.latimes.com Author: Thomas H. Maugh II One in five Americans lights up regularly. If all states had prevention programs like those in California and Utah, 5 million fewer people would be smoking, the agency says. After 40 years of continual declines, the smoking rate in the United States has stabilized for the last five years, with one in every five Americans still lighting up regularly, the Centers for Disease Control and Prevention said Tuesday. Moreover, more than half of all children are exposed to toxic, secondhand smoke and 98% of those who live with a smoker have measurable levels of toxic chemicals in their blood stream, setting them up for future harm from cancer, heart disease and a variety of other ailments. "If you smoke and have children, don't kid yourself. Your smoke is harming your children," CDC Director Dr. Thomas R. Frieden said in a news conference. Using products marketed as being less harmful is no panacea, he added. "All cigarettes kill equally, and we know that light and low-tar cigarettes are no less likely to kill you." Despite the reduction in smoking over the last four decades, Frieden said, smoking remains the No. 1 cause of preventable deaths in the United States. Every year, an estimated 446,000 Americans die from smoking-related diseases. The good news is that some states are making progress in combating smoking. Utah has the lowest smoking rate at 10%, and California is second with a rate just below 13%, according to CDC figures. [...]

2010-09-13T08:07:11-07:00September, 2010|Oral Cancer News|
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‘I like my odds’ against cancer, Michael Douglas says

By Donna Freydkin Source:USA TODAY NEW YORK— They don'tmake'em like Michael Douglas anymore. In this age of crass reality upstarts and pampered starlets, he's a movie star of the old school. And even in his third week of grueling radiation treatments for Stage IV throat cancer, Douglas is a gentleman first, making sure a guest is comfortable on the green sofa in his family room and apologizing repeatedly for being a little off his game after a particularly brutal radiation session this morning. He hasn't pondered the meaning of life yet, or gone on any soul-searching journeys to faraway lands. "I like my odds. I'm not dealing with mortality issues until they tell me, 'Oops, we have to go back and do surgery' or something like that," Douglas says. "The tumor is shrinking. The odds are good." He pauses a beat, smiles, and takes a sip of the aloe-infused water he's drinking to soothe his throat. "I haven't found God yet." There's no woe-is-me self-pity as Douglas manages to poke fun at his condition. "There's never a really great time for cancer, but this is one for the books," he cracks. "Actually I was doing really good, but today has not been great." It has been a doozy of a year for Douglas, 65, full of highs and staggering lows. After little-seen turns in 2009's Ghosts of Girlfriends Past and 2007's King of California, he earned positive reviews for playing a sleazy seducer in this year's intimate drama Solitary Man. [...]

2010-09-10T21:33:53-07:00September, 2010|Oral Cancer News|
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Organ preservation for advanced resectable cancer of the base of tongue and hypopharynx: a Southwest Oncology Group trial

Source: J Clin Oncol 23:88-95 Author: Susan G. Urba et al. Purpose: The Southwest Oncology Group designed a phase II trial for patients with base of tongue or hypopharyngeal cancer to evaluate the complete histologic response rate at the primary site after induction chemotherapy followed by chemoradiotherapy for responders. Secondary end points were the rate of organ preservation and the need for salvage surgery. Patients and Methods: Fifty-nine eligible patients were enrolled; 37 had base of tongue cancer, and 22 had hypopharynx cancer. Forty-two percent had stage III disease, and 58% had stage IV disease. Induction chemotherapy was two cycles of cisplatin 100 mg/m2 and fluorouracil 1,000 mg/m2/d for 5 days. Patients who had a greater than 50% response at the primary site were treated with radiation 72Gy and concurrent cisplatin 100 mg/m2 for three cycles. Patients with less than partial response at the primary had immediate salvage surgery. Results: Forty-five patients (76%) had a greater than 50% response at the primary after induction chemotherapy; 43 went on to receive definitive chemoradiotherapy. Thirty-two patients (54%) achieved a histologic complete response at the primary site, and an additional nine patients had a complete clinical response, but biopsy was not done. Seventy-five percent of patients did not require surgery at the primary tumor site. The 3-year overall survival was 64%. The 3-year progression-free survival with organ preservation was 52%. Conclusion: Patients with base of tongue or hypopharyngeal cancer treated with this regimen of induction chemotherapy followed by definitive chemoradiotherapy have a good [...]

2010-09-07T07:46:33-07:00September, 2010|Oral Cancer News|
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More ’empowered’ patients question doctors’ orders

Source: www.usatoday.com Author: Mary Brophy Marcus In the past, most patients placed their entire trust in the hands of their physician. Your doc said you needed a certain medical test, you got it. Not so much anymore. Jeff Chappell of Montgomery, Ala., recalls a visit a couple of years ago to a Charlotte emergency room, near where the family used to live, with his wife, Jacqueline, who has adrenal failure. "I blew up loud enough for everyone in the ER to hear me explain that while we were insured, an MRI was about a $1,000 co-pay," Chappell says. The couple knew her symptoms well (primarily stomach pain), knew that an MRI was not necessary under the circumstances and knew that a cortisone shot was what she needed. "The doctor walked off in a huff," Chappell says, but later came back and "compromised" by agreeing to give his wife the shot, but not before taking an abdominal X-ray to rule out other problems first. Many physicians say an increasing number of patients are getting involved in decisions about their medical care, including medication choices, whether they need a specialist, and especially whether they need expensive diagnostic tests, which some health economists say are driving up the cost of health care. 'Shared decision model' "There have been big changes," says Patrick McManus, residency director of family and community medicine at Thomas Jefferson University in Philadelphia. "Some of my older patients are still more deferential, but more and more, we talk with patients [...]

2010-09-03T20:58:23-07:00September, 2010|Oral Cancer News|
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Michael Douglas talks cancer with Letterman: stage 4, 80% odds

Source: www.huffingtonpost.com Author: staff Michael Douglas says he faces an "eight-week struggle" against throat cancer but is optimistic about his chances for recovery. During an appearance Tuesday on David Letterman's "Late Show," the actor said he had just finished his first week of radiation and chemotherapy. That drew a surprised reaction from Letterman. "You've never looked better to me, and this proves that you're a tough guy, for God's sakes," the talk-show host said, drawing cheers from the studio audience, according to a CBS news release. "Let's just say ... I'm pretty lit up right now," Douglas replied. The disease was diagnosed three weeks ago, he said, although he had complained of a very sore throat earlier this year and had undergone testing that failed to find a cause. Douglas, 65, who has two children with Catherine Zeta-Jones, said he enjoyed the summer traveling with his family before returning to the doctor. A biopsy found he had late, stage-four cancer, "which is intense, and so they've had to go at it," he said. However, Douglas said, the cancer remains above the neck and that means expectations are good, with an 80 percent or better chance of recovery. Asked by Letterman about his personal habits, he said he had smoked and consumed alcohol. According to a National Institutes of Health website, use of tobacco or alcohol are among the factors that put people at risk of developing throat cancer. Combining tobacco and drinking increases the risk. Most throat cancer develops in [...]

2010-09-01T13:10:43-07:00September, 2010|Oral Cancer News|
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Can saliva-based HPV tests establish cancer risk and guide patient management?

Source: Oral and Maxillofacial Pathology doi:10.1016 Author: Mark W. Lingen, DDS, PhD Section Editor, Oral and Maxillofacial Pathology Head and neck squamous cell carcinoma (HNSCC) is the 6th most common malignancy in the world today.1 Despite numerous advances in treatment, the 5-year survival rate has remained modest. This poor outcome is due to several factors, including delayed diagnosis. Therefore, improved early detection and effective prevention strategies are critical components for management of this malignancy. The etiology of classical HNSCC has been attributed to chronic exposure to tobacco and alcohol.2 In addition, there is now sufficient evidence to support the contention that high-risk forms of the human papillomavirus (HPV) are a major causative factor for HNSCC of the tonsil, base of tongue, and oropharynx.3-8 The increasing importance of HPV in oropharyngeal HNSCC has raised considerable concern and uncertainty among healthcare professionals and patients. For example, I am often asked to describe the clinical features of HPV-associated premalignant lesions. Unfortunately, to my knowledge, the clinical spectrum of HPV-associated premalignant disease has not been adequately described. Furthermore, because this subset of HNSCC often develops in hard to- examine locations, such as tonsillar crypts, it can be exceedingly difficult to even identify the carcinomas. In the absence of such information, how can clinicians identify patients that are at increased risk for harboring an HPV-associated premalignant lesions or HNSCC? Recently, a large commercial diagnostic lab began offering a saliva-based test for the identification of oral HPV infections. As a result of this new offering, I [...]

2010-08-31T12:09:37-07:00August, 2010|Oral Cancer News|
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Tobacco signs still target city’s poorer areas

Source: www.boston.com Author: Stephen Smith The signs, wrought in soothing italics, beckon with promises of tobacco “pleasure!’’ at low, low prices. Across Dorchester, Mattapan, and other city neighborhoods, big signs and little signs, vertical signs and horizontal signs trumpet the availability of cigarettes at corner stores and gas stations. They are plastered on façades and propped against windows, affixed to light poles and gas pumps. A dozen years after Massachusetts attempted to ban storefront tobacco ads within 1,000 feet of schools and playgrounds, a prohibition thwarted by a tobacco company’s legal challenge, the signs remain prolific and prominent in Boston’s lower-income neighborhoods, especially those with substantial African-American and Hispanic populations. But now, empowered by Congress to regulate tobacco companies, the Food and Drug Administration is taking steps that could rein in the pastel-hued signs that industry foes say entice young customers to start smoking. With cigarette advertising banished from the airwaves and largely absent from billboards, storefronts are some of the last bastions of tobacco marketing. The continued presence of the ads is a testament, researchers said, to the deep reach of cigarette makers in poorer communities, where merchants said company representatives sometimes personally attach ads to store exteriors. “Tobacco advertising is still alive and well,’’ said Dr. Michael Siegel, a tobacco control specialist at the Boston University School of Public Health. “There’s a widespread perception that somehow the tobacco advertising has gone away, that it’s been taken care of, that we don’t have to worry about this anymore. But [...]

2010-08-31T11:48:38-07:00August, 2010|Oral Cancer News|
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