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On the Call: Altria Group CEO Michael Szymanczyk

Source: Business Week Richmond, VA Like other tobacco companies, Altria Group Inc. is focusing on cigarette alternatives such as cigars, snuff and chewing tobacco for sales growth as tax increases, smoking bans, health concerns and social stigma make the cigarette business tougher. The smokeless tobacco category is growing at about 7 percent a year, but still remains small compared with cigarettes. The parent company of the nation's biggest cigarette maker, Philip Morris USA, said Wednesday that volumes for its smokeless tobacco segment, which includes Copenhagen and Skoal, as well as Marlboro Snus, grew 16.4 percent in the third quarter and revenues excluding excise taxes increased about 11 percent to $363 million. In a conference call with analysts regarding Altria's third-quarter earnings, CEO Michael E. Szymanczyk talked about the company working with retailers to better align their shelf space with changes in the tobacco industry. QUESTION: Is the investment to help retailers reallocate their space and improve their display units for smokeless products meaningful to call out? RESPONSE: This is a category that has grown pretty substantially here over the last few years, but in retail stores, there hasn't been any significant movement in the space. At the same time, the cigarette category has declined in volume. And while inventories have come down in the cigarette business, the actual physical space devoted to cigarettes hasn't meaningfully changed. There's a good opportunity to play catch-up here. ... We're helping retailers redistribute their space so it's more consistent with their sales, and that [...]

2010-10-21T12:27:20-07:00October, 2010|Oral Cancer News|
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Turmeric makes chemo more effective

Source: timesofindia.indiatimes.com Author: staff Researchers with UCLA's Jonsson Cancer Center have found that curcumin, the major component in the spice turmeric, when combined with the drug Cisplatin enhances the chemotherapy's suppression of head and neck cancer cell growth. In India, women for years have been using turmeric for medicinal purposes, as an anti-aging agent rubbed into their skin, to treat cramps during menstruation, as a poultice on the skin to promote wound healing and as an additive in cosmetics, said scientist Eri Srivatsan, an adjunct professor of surgery and a Jonsson Cancer Center researcher. Srivatsan, along with Dr. Marilene Wang, a professor of head and neck surgery, lead author of the study and a Jonsson Cancer Center researcher, has been studying curcumin and its anti-cancer properties for six years. A 2005 study by Wang and Srivatsan first showed that curcumin suppressed the growth of head and neck cancer cells, first in cells and then in mouse models. In the animal studies, the curcumin was applied directly onto the tumours in paste form because it did not dissolve in saline, which would have allowed it to be injected. In need of a better way to deliver the curcumin, the team collaborated with Dr. Kapil Mehta of M.D. Anderson Cancer Center and found that encapsulating the curcumin in a liposome, an artificially prepared vehicle that enclosed the spice component within its membrane, made the treatment injectable. The curcumin was injected into the tail vein of a mouse, where it circulated into the [...]

2010-10-20T08:54:24-07:00October, 2010|Oral Cancer News|
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Latest generation VELscope device approved for sale by Health Canada

Source: www.sfgate.com Author: staff LED Dental Inc. announced today that its VELscope Vx Enhanced Oral Assessment system was granted a medical device license and approved for sale by Health Canada. The VELscope Vx system's unique cordless design and affordable pricing make it easier than ever for dental practices to detect oral cancer and other forms of oral disease. The first-generation VELscope device was introduced in 2006, with the second-generation version launching two years later. In total, LED Dental has sold almost 6,000 units of the two devices, which have been used to conduct almost 10 million enhanced oral soft tissue exams worldwide. Oral soft tissue exams not only help detect all types of oral disease but are also a key element of an oral cancer screening protocol. Today, VELscope fluorescence visualization technology is used to conduct more enhanced oral exams than any other detection technology in the world. "We are extremely excited about the potential of the VELscope Vx system to significantly increase the number of dental practices conducting oral cancer screenings," said Peter Whitehead, founder and CEO of LED Dental. "The device's portability makes it easy to transport between operatories within the dental practice, and its attractive pricing makes it possible for practices to charge very low exam fees to their patients." Oral cancer kills one North American every hour of every day. According to the SEER database, oral cancer has a higher mortality rate than several better-publicized cancers, such as cervical cancer and testicular cancer. Some oral cancers [...]

2010-10-20T08:46:07-07:00October, 2010|Oral Cancer News|
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Virus Behind Oral Cancer Epidemic

Study Shows 'Startling Increase' in Oral Cancer Is Linked to Sexually Transmitted HPV Source: WebMD Health News By: Daniel DeNoon Researchers warn of an ongoing epidemic of oral cancer caused by the sexually transmitted human papillomavirus (HPV). A study in Stockholm, Sweden, finds that cases of oral cancer -- primarily cancer of the tonsils -- increased sevenfold from 1970 to 2007. They find that while HPV caused only 54% of oral cancers from 1998-1999, it caused 84% of these cancers in 2006-2007. "It looks like HPV-positive oral cancers are rising quite sharply in the past 10 years, while HPV-negative oral cancers went down. That is why we say it is an epidemic," study leader Tina Dalianis, MD, PhD, professor of tumor biology at Sweden's Karolinska Institute, tells WebMD. HPV is a well-known cause of cervical cancer. But researchers have only recently begun to appreciate its role in oral cancer, says HPV-oral cancer expert Gypsyamber D'Souza, PhD, of Johns Hopkins Bloomberg School of Public Health. "Yes there is a startling increase in the incidence of oropharyngeal cancer, and that increase is being driven by HPV," D'Souza tells WebMD. "But while many experts agree that there's an epidemic rise in HPV-related oral cancer, the cancer remains rare." The risk of developing oral cancer increases with the lifetime number of oral or vaginal sex partners, but many people with HPV-related oral cancer have five or fewer lifetime sexual partners. Men are more likely to get oral cancer than are women, and people with [...]

2010-10-18T09:25:43-07:00October, 2010|Oral Cancer News|
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Oral Cancer Foundation founder named Survivor Circle Award winner by ASTRO

The American Society for Radiation Oncology (ASTRO) has named Brian Hill of Newport Beach, Calif., as its 2010 Survivor Circle Award winner. Hill will be recognized with a trophy and a $1,000 prize during the Awards Ceremony on Tuesday, November 2, 2010, during ASTRO's 52nd Annual Meeting in San Diego. He has chosen to donate the funds from the award to benefit The Oral Cancer Foundation, the nonprofit he started a decade ago. The Survivor Circle Award recognizes a cancer survivor who has given back to the community by devoting his or her time to helping others with cancer. Hill was diagnosed with Stage 4 metastatic tonsil cancer in 1997. When he was going through treatment, he had many questions about side effects and realized there was a lack of information and awareness about head and neck cancer even though the disease has a very high death rate, due to it being caught at a late stage in most cases. "There was a huge lack of information available, and I was desperate to find someone to talk to who had gone through the same thing I was experiencing," Hill said. "I knew that if I was feeling this way, there had to be others feeling my frustrations too. I then became a student of the disease. " After Hill completed his grueling but successful radiation treatments at M.D. Anderson Cancer Center in Houston, he and his wife Ingrid founded The Oral Cancer Foundation in 1999, which is now a national [...]

2010-10-15T15:42:57-07:00October, 2010|OCF In The News|
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A personalized and integrative approach to cancer care

Source: www.mdnews.com Author: staff With the recent move to a newly renovated office and infusion center at the corner of Tank Farm Road and Broad Street in San Luis Obispo, Tom Spillane, M.D.; Jim Malone, M.D.; and Deborah Villa, M.D., have renamed the practice Coastal Integrative Cancer Care (CICC), in order to reflect their commitment to a multidisciplinary, collaborative approach to the treatment of cancer. The group, along with Tim Souchek, PA-C, and a dedicated professional oncology-nursing staff, has been the provider of state-of-the-art medical oncology and hematology care in San Luis Obispo County for more than 10 years. However, the new CICC is now able to maximize patients’ treatment outcomes by integrating the latest scientific and technologic information with complementary therapies. Integrative medicine refers to the fusion of complementary therapies (for which there is evidence of safety and effectiveness) with standard Western medical treatments. The term “integrative oncology” has been developed to describe the integration of mainstream cancer care with nonpharmacologic, evidence-based complementary therapies, examples of which include: dietary changes, exercise, physical therapy, naturopathic medicine, chiropractic medicine, acupuncture, massage therapy, aromatherapy, Reiki, Yoga, meditation, guided imagery/hypnotherapy, expressive arts, Tai Chi, Qigong, resistance training, aerobic training programs and dietary interventions. CICC incorporates these interventions through a host of local providers and resource centers, including the Hearst Cancer Resource Center and The Wellness Community. CICC makes every effort to tailor treatments to individual patients based on science and clinical research. The term “personalized medicine” has also been recently coined to describe [...]

2010-10-13T14:48:00-07:00October, 2010|Oral Cancer News|
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Lilly presents new data in head and neck cancer – a difficult to treat cancer with poor survival rates

Source: www.prnewswire.com Author: press release Eli Lilly and Company announced today that its global Phase III trial evaluating Alimta® (pemetrexed for injection) in combination with cisplatin in patients with recurrent or metastatic squamous cell cancer of the head and neck (SCCHN) did not meet its primary endpoint for overall survival. Data were presented for the first time today at the 35th Annual Meeting of the European Society for Medical Oncology (ESMO). The Phase III study, the largest trial conducted in SCCHN to date, evaluated Alimta in combination with cisplatin compared with placebo plus cisplatin given every three weeks in a total of 795 patients. The primary objective of the study was to determine overall survival. Patient quality of life was also assessed, in addition to several pre-planned sub-group analyses. The Alimta/cisplatin regimen showed a median overall survival of 7.3 months compared with 6.3 months with cisplatin alone, a result not considered a statistically significant improvement (p=0.082). There was no significant difference in the quality of life scores for patients treated with either ALIMTA/cisplatin or cisplatin alone (p=0.200). As a result, Lilly will not be submitting marketing authorization applications for Alimta in SCCHN with either the U.S. Food and Drug Administration (FDA) or the European Medicine Agency (EMA). "The fact that combination treatment with pemetrexed and cisplatin did not improve overall survival in this study is disappointing, although perhaps not surprising given how difficult it can be to effectively treat metastatic or locally advanced head and neck cancer," said the study's [...]

2010-10-13T14:39:16-07:00October, 2010|Oral Cancer News|
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Research shows lifestyle choices increase oral cancer risk

Source: www.cosmeticdentistryguide.co.uk Author: staff Research conducted by a team at Aberdeen University has shown that lifestyle choices are increasing the risk of oral cancer. The study showed that young people are increasing their risk of developing forms of cancer known as upper aero-digestive tract by choosing to drink alcohol on a regular basis and smoke. Diet also plays a significant part and those with a poor diet, lacking in essential nutrients provided by fruit and vegetables, have a much higher risk of developing AEDT cancers. The study was conducted over a five year period; data from 350 patients under the age of 50 with AEDT cancer was analysed alongside data from 400 patients who did not have AEDT cancer. The study concluded that nine out of ten cases of cancer were associated with regular consumption of alcohol, smoking and a poor diet. Oral cancer is becoming increasingly common, yet many people are still aware of the symptoms and signs. Dentists are campaigning to raise awareness of oral cancer and increase the media profile so that people are aware of the importance of regular dental check-ups and know which signs to look out for. Common symptoms of oral cancer include white or red patches in the mouth, sores which do not heal and unusual swellings in the mouth or throat. The British Dental Health Foundation are launching Mouth Cancer Action Month in November; it is hoped that the events and programmes will educate people about oral cancer and encourage them to [...]

2010-10-13T14:31:13-07:00October, 2010|Oral Cancer News|
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Baseball Hall of Famer Tony Gwynn to begin oral cancer treatment

The Associated Press Baseball Hall of Famer Tony Gwynn soon will begin treatment for parotid cancer, the San Diego Union-Tribune reported Saturday. The cancer was discovered last month after Gwynn, 50, underwent his third bout of surgery since 1997 to remove a tumor on his parotid gland, which pumps saliva into the mouth. The former San Diego Padres star said he faces seven to eight weeks of five-day-a-week radiation treatments and once-a-week chemotherapy treatments, the Union-Tribune reported. Gwynn said doctors told him they feel they caught the cancer early and "there was not much of it there." "They say this is a slow-moving but aggressive form of cancer," Gwynn told the paper. "I'm going to be aggressive and not slow moving in treating this." Gwynn suspects the cancer could be linked to his career-long practice of using chewing tobacco. "I haven't discussed that with the doctors yet, but I'm thinking it's related to dipping," said Gwynn, who resumed using chewing tobacco after the first two surgeries. Gwynn is San Diego State's baseball coach, and the school confirmed Gwynn's condition to The Associated Press. Gwynn plans to return to his alma mater, which he has coached since 2003. He retired from the majors in 2001 after 20 seasons with the Padres, in which he won a National League record-tying eight batting championships and was named to the All-Star Game 16 times.

2010-10-10T11:28:00-07:00October, 2010|Oral Cancer News|
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Government Certified: What’s Causing Cancer — Research Summary

CANCER-INSIDE AND OUT: Cancer is one of the most prominent diseases in the world. According to the National Cancer Institute, "cancer is a renegade system of growth inside the human body. The changes that must occur inside for cancer to flourish are genetic changes, but factors outside the body also play a role."  Outside factors, such as: diet, smoking, alcohol use, hormone levels, and even exposure to certain chemicals and viruses over time, can all work together to create defects and maturation in cells. Furthermore, they go on to explain that environmental, in science, means, everything outside the body, in the environment, that enters and interacts with it. This type of exposure can also include things such as: sunshine, rain, water, food intake, and workplace environment. Researchers have concluded approximately 67 percent of all cancers are due in some part to the environment. Feeling like you can't go anywhere now without being faced with cancer? The good news is these risks can decrease significantly if lifestyle changes are made. The National Cancer Institute suggests about one third of all cancer deaths could have been prevented if lifestyle changes were made, such as avoiding or completely eliminating tobacco and alcohol use. NOT JUST ON THE OUTSIDE: Environmental factors are not the only culprit when it comes to cancer. A lot of cancer is gene related and based on our composition from within. Random gene changes occurring now, as well as gene changes that occur from cell growth and division, accumulate and [...]

2010-10-08T11:32:47-07:00October, 2010|Oral Cancer News|
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