Charlotte Parker, Author at Oral Cancer News

New oral cancer data could prompt new treatments

Source: The Columbus Disbatch Author: Misti Crane Doctors are focusing increasingly on the role that human papilloma virus plays in oral cancer, and new research is prompting hope that treatments can be better tailored to patients. People with oral cancer have a better chance of surviving if the cancer is linked to HPV, according to a new study led by an Ohio State University researcher. Dr. Maura Gillison and her colleagues found that 82 percent of those with HPV-positive tumors in the back of their mouths survived at least three years, compared with 57percent of those with mouth tumors not tied to HPV. Their study included 323 oropharyngeal cancer patients. HPV, which is spread by sexual contact, is the virus that also causes cervical cancer. It can cause cancer of the mouth through oral sex. The research took into account other risk factors such as tobacco use. It was published online yesterday in the New England Journal of Medicine. This study should prompt more studies and advances in treatment, Gillison said. For example, it could be that patients with a better prognosis could have less radiation and suffer fewer side effects, she said. Side effects of treatment include trouble swallowing, dental problems, difficulty speaking and inflexibility in the neck. Gillison also presented new data yesterday at the American Society of Clinical Oncology meeting in Chicago. The data showed a worse outcome for smokers who have HPV-positive cancers than for patients with the same type of cancer who don't smoke. The risk [...]

Charlotte Parker2010-06-09T10:00:14-07:00June, 2010|OCF In The News, Oral Cancer News|

FDA to examine cigarette ingredients

Source: Health.com Author: Amanda Gardner MONDAY, JUNE 7 (Health.com) — If you want to know what’s in your TV dinner or Twinkies—a big if—all you need to do is look on the package. But if you smoke cigarettes and want to know what you’re inhaling, you’re out of luck. For years, tobacco companies have been lacing cigarettes with hundreds of chemicals and additives ranging from ammonia to cocoa, reportedly to heighten the kick of nicotine, improve flavor, and mask the harshness of smoke. Very little is known about the health effects of these ingredients, however, since the tobacco industry isn’t required to disclose them publicly or explain their purpose. The mystery may soon come to an end. On Tuesday, a Food and Drug Administration (FDA) advisory panel will meet to investigate what “harmful or potentially harmful” ingredients are in the more than 300 billion cigarettes smoked in the U.S. each year. After a second meeting this summer, the panel will provide a list of ingredients and recommendations to the FDA, which was granted the authority by Congress to regulate tobacco products in 2009. “Maybe with a new FDA ruling, companies will have to tell us what they put in these products and why,” says Norman Edelman, MD, the chief medical officer of the American Lung Association. “The concern is that these [ingredients] have health risks and we don’t really know what they are.” Sixty years ago cigarettes contained few additives. But as tobacco companies sought to reduce the levels of nicotine [...]

Charlotte Parker2010-06-09T12:38:21-07:00June, 2010|Oral Cancer News|

New report compares radiation approaches in head and neck cancer

Source: MedScape Today Author: Nick Mulcahy June 1, 2010 — Intensity-modulated radiation therapy (IMRT) for head and neck cancer leads to fewer cases of xerostomia, but has not yet been proven to be more successful than any other kind of radiation therapy in reducing tumors or improving survival, according to a new comparative-effectiveness review funded by the federal Agency for Healthcare Research and Quality (AHRQ). The review compares the effectiveness of 4 types of radiotherapy (IMRT, 3DCRT, 2DRT, and proton-beam therapy) in terms of tumor control, overall survival, adverse events, and quality-of-life issues. Many scientists consider IMRT to be theoretically better able to target cancerous cells while sparing healthy tissue than either 3DCRT or 2DRT, but more research is needed, the authors of the report point out. The report, entitled Comparative Effectiveness and Safety of Radiotherapy Treatments for Head and Neck Cancer, is authored by the Blue Cross and Blue Shield Association's Technology Evaluation Center Evidence-Based Practice Center. The late adverse effect of xerostomia, also known as dry mouth, is less common than in the past because the use of IMRT has allowed radiation oncologists to spare most patients' salivary glands from radiation as part of treatment planning, an expert recently told Medscape Oncology. Sparing salivary glands has become standard among clinicians who use IMRT, said Avraham Eisbruch, MD, professor of radiation oncology at the University of Michigan Medical School and Comprehensive Cancer Center in Ann Arbor. Dr. Eisbruch's comments came in the context of his study on the use of IMRT [...]

Charlotte Parker2010-06-04T16:26:20-07:00June, 2010|Oral Cancer News|

U.S. cigarette brands tops in cancer causing chemicals

Source: CNN Author: Miriam Falco Smokers of U.S. brand cigarettes may get more bang for their buck in the worst way according to a small study conducted by the Centers for Disease Control and Prevention. Researchers found U.S. made cigarettes contain more cancer-causing chemicals than some cigarettes brands made elsewhere around the world. “Not all cigarettes are made alike” says Dr. Jim Pirkle, deputy director for science at the CDC’s National Center for Environmental Health. He says this is the first study to show that “U.S. cigarettes have more of the major carcinogen [TSNAs] than foreign made cigarettes." TSNAs are “tobacco-specific nitrosamines,” the major cancer-causing substance in tobacco. 126 smokers in five cities – Waterloo, Ontario; Melbourne, Victoria (Australia); London, England, Buffalo, New York, and Minneapolis, Minnesota – were recruited for this study. They were between the ages of 18 and 55 and smoked at least 10 cigarettes a day for the past year and had been brand loyal for at least three months. The cigarettes smoked by the study recruits represented some of the more popular brands for each country including: Players light and DuMaurier in Canada; Marlboro, Newport Light, Camel Light in the U.S.; Peter Jackson and Peter Stuyvesant in Australia; and Benson & Hedges and Silk Cut Purple in the United Kingdom. Scientists analyzed more than 2,000 cigarette butts to get the data they are reporting today, says Pirkle. When researchers compared cigarette brands in the U.S. to those in Canada and Australia, they found three times higher [...]

Charlotte Parker2010-06-04T13:06:10-07:00June, 2010|Oral Cancer News|

Oral cancer doesn’t silence North Carolina man

Source: The Cherokee Scout Author: Lizz Harold Marble – Switching out one form of tobacco for another, Rick Miller, 44, learned how to quit smoking and dipping the hard way. Miller went to a doctor in March to see if an ulcer inside his mouth could be removed. He expected a round of antibiotics or oral surgery. He figured he would be back to dipping as usual after it was taken care of. “I really didn’t have any symptoms. I got an ulcer underneath my tongue. They thought it was all it was,” Miller said. Miller’s wife, Nicolia, did what most people do when they suspect they have an ailment. She went online and did an Internet search. After doing her own research, she was convinced it was mouth cancer, and Miller decided to see a specialist to see if their suspicions were correct. “Everything happened so fast after that,” Miller said. Informed by the specialist that he had oral cancer, he was immediately set up with a chemotherapy and radiation doctor. The father of four, two who are twin toddlers, had to undergo bouts of chemotherapy – including days where it was pumping into him everyday. From dipping to smoking Eight years ago, he stopped a 21-year smoking habit and began dipping tobacco. After more than 30 years of combined tobacco use, Miller has been forced to give up his addiction. “I gave up smoking and needed something to fill the void,” Miller said. He said he got a [...]

Charlotte Parker2010-06-03T15:55:07-07:00June, 2010|Oral Cancer News|

Big Tobacco Files Lawsuit Over Anti-Smoking Ads

Source: Gothamist Author: John Del Signore A Board of Health directive could soon require any retailers selling cigarettes to display graphic warning signs (like the sample here) about the dangers of smoking, plus information on where to seek help quitting. But that would violate their First Amendment rights by focring them to "undertake graphic advocacy on behalf of the city," according to a lawsuit filed in Manhattan Supreme Court today by cigarette manufacturers' R.J. Reynolds, Philip Morris and Lorillard, along with two Queens convenience stores and two retail groups. The signs, which vividly depict the insalubrious effects of smoking on various parts of the human body (think mouth cancer and heart disease), "do not describe the risks of smoking in purely factual terms," the lawsuit claims.Furthermore, "The mandated signs crowd out other advertisements and otherwise dominate the point of sale in many smaller establishments, to the exclusion of merchandise or other messages chosen by the store owners. The signs thus deprive retailers of the limited space available for communicating with their customers and thereby restrict their speech." Say, it's nice to see Big Tobacco sticking up for the little guy, innit? In a statement, the Health Department says: Tobacco is an addictive drug that kills some 7,500 New Yorkers every year. It disables many more. Yet studies show that many smokers are still unaware of the full risks that smoking poses. By requiring cigarette vendors to post warning signs at the point of sale in retail outlets, New York City is trying to alert [...]

Charlotte Parker2010-06-03T15:40:35-07:00June, 2010|Oral Cancer News|

Free oral cancer screenings offered June 5th at NASCAR Event, at Nashville SuperSpeedway

Source: The Tennessean Author: Staff One person dies each hour of each day from oral cancer in the United States, but it only takes a three-minute oral exam to potentially save a life. On June 5, local dentists and hygienists will gather at the Nashville SuperSpeedway for the NASCAR Nationwide Series, to conduct free oral cancer screenings for the general public. The event is being sponsored by the Oral Cancer Foundation, to educate others about the importance of prevention and early detection through check-ups and awareness of important warning signs. The free exams will be conducted from 2-6 p.m. at the Speedway. Approximately 35,000 people in the U.S. will be newly diagnosed with oral cancer in 2010, which includes mouth cancer, tongue cancer and throat cancer. When found early, there is an 80 to 90 percent survival rate. However, due to a lack of public awareness, the majority of cases are found as late-stage cancers that can be killers. The Oral Cancer Foundation is a national public service, non-profit entity designed to reduce suffering and save lives through prevention, education, research, advocacy, and support activities. Check outwww.oralcancerfoundation.org to learn more about risk factors, signs and symptoms, treatments, current research and up-to-date oral cancer related news, among other important information. A free patient/survivor discussion forum is also open to the public, where those currently fighting oral cancer can gain insights and inspiration from those who have been there before them. The NASCAR Nationwide Series returns to Nashville Superspeedway on June 5 [...]

Charlotte Parker2010-06-03T16:00:35-07:00June, 2010|OCF In The News, Oral Cancer News|

FDA tobacco regulator promises firm approach, open mind

Source: The Wall St. Journal Author: David Kesmodel WILLIAMSBURG, Va.—The top tobacco regulator at the Food and Drug Administration signaled to industry executives Monday that he would take a firm approach to overseeing the industry, but pledged to keep an open mind about new products and ideas to reduce tobacco-related illnesses. Dr. Lawrence Deyton, director of the agency's Center for Tobacco Products, said in a speech at an annual tobacco-industry conference here that his job "is to address this enormous toll of confusion, suffering and death caused by the current state of tobacco use in this country." In one of his first speeches to a large group of tobacco executives, Mr. Deyton told members of the Tobacco Merchants Association that he would place strong emphasis on reducing the number of minors who become tobacco users. He said 4,000 kids begin smoking each day, on average, and 1,000 become regular users. He reiterated his concern that new, dissolvable forms of smokeless tobacco produced by companies such as Reynolds American Inc. are candy-like in their appearance. Reynolds is complying with a review of such products by the FDA and has said its dissolvable products, which are being test-marketed in three cities, are made and marketed for adults. Mr. Deyton, a longtime public-health expert, began his job in September, a few months after the agency was given broad powers to regulate the industry under a landmark law signed by President Obama. The agency is still in the early stages of solidifying the framework under [...]

Charlotte Parker2010-05-29T11:00:45-07:00May, 2010|Oral Cancer News|

Critical impact of radiotherapy protocol compliance and quality in the treatment of advanced head and neck cancer

Source: Stanford University Author: Staff Departments of Radiation Oncology and Medical Oncology, and Centre for Biostatistics and Clinical Trials, Peter MacCallum Cancer Centre; University of Melbourne, Melbourne, Australia; Department of Radiation Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada; Department of Radiation Oncology, Hospital General Vall d'Hebron, Barcelona, Spain; Department of Radiation Oncology, University of Massachusetts Medical Center, North Worcester, MA; Department of Radiation Oncology, H. Lee Moffitt Cancer Center, Tampa, FL; Department of Radiation Oncology, Genolier Swiss Medical Network, Geneva, Switzerland; Department of Radiation Oncology, Institut Gustave Roussy, Villejuif, France; Quality Assurance Review Center, Providence, RI. PURPOSE To report the impact of radiotherapy quality on outcome in a large international phase III trial evaluating radiotherapy with concurrent cisplatin plus tirapazamine for advanced head and neck cancer. PATIENTS AND METHODS The protocol required interventional review of radiotherapy plans by the Quality Assurance Review Center (QARC). All plans and radiotherapy documentation underwent post-treatment review by the Trial Management Committee (TMC) for protocol compliance. Secondary review of noncompliant plans for predicted impact on tumor control was performed. Factors associated with poor protocol compliance were studied, and outcome data were analyzed in relation to protocol compliance and radiotherapy quality. Results At TMC review, 25.4% of the patients had noncompliant plans but none in which QARC-recommended changes had been made. At secondary review, 47% of noncompliant plans (12% overall) had deficiencies with a predicted major adverse impact on tumor control. Major deficiencies were unrelated to tumor subsite or to T or N stage (if N+), [...]

Charlotte Parker2010-05-27T07:47:24-07:00May, 2010|Oral Cancer News|

Swedish Match snuff separates from snus pack

Source: Tobacco News Author: Staff Swedish Match North America, maker of moist snuff, cigars and chewing tobacco, is taking a different approach to marketing its Swedish-style snus tobacco product when compared to two other U.S. tobacco companies offering the product, according to a report by the Richmond Times-Dispatch. Swedish Match marketers began a sampling effort in Vail, Colo., and now are handing out silvery sample packs of General Snus on Wall Street — a sign that the product will be positioned as a high-end item, the report stated.”We are emphasizing the Swedish cachet,” Richard Flaherty, president of Swedish Match North America, told the paper when asked about the sampling push. In addition, Swedish Match’s General brand is more expensive than either the Marlboro brand by Altria Group’s Philip Morris unit, or Reynolds American’s Camel brand. The premium positioning is not the only difference in its marketing strategy.”We’re not marketing snus as something for when you can’t smoke. We’re marketing it as an alternative to cigarettes,” Flaherty said in the report. The company is looking for smokers who don’t want to smoke at all, rather than using the product as a fill-in to cigarettes, the report stated. For this reason, the company identified a key target group in parents who worry about secondhand smoke at home, Flaherty said. In addition, the focus on niche consumer groups rather than the general tobacco market is a reason why General isn’t appearing in convenience stores. Instead of fighting for shelf space with two of the toughest competitors in [...]

Charlotte Parker2010-05-27T07:48:07-07:00May, 2010|Oral Cancer News|

Oral Cancer News
Compiled by The Oral Cancer Foundation

About Charlotte Parker