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In Memoriam: Jimmie C. Holland, MD

The Oral Cancer Foundation is deeply saddened by the passing of OCF Science Advisory Board member, Dr. Jimmie C. Holland. When our organization was in it’s infancy, Dr. Holland was an early supporter of OCF.  She was one of the first in the profession to focus attention on the mental well being of cancer patients. With OCF being a foundation that is heavily geared to funding the advancement of research, and being very hard science and research oriented,  her compassion for the mental health of cancer patients was a key component in humanizing our efforts, and ensuring that we stayed people centric.  We are tremendously grateful for her advanced work in Psycho-oncology, the good it has done for so many in the oral cancer community, and the guidance she offered us. She will be missed by many. Author: William Breitbart Source: https://blog.oup.com Date: Feb. 23, 2018 Jimmie C. Holland, MD, internationally recognized as the founder of the field of Psycho-oncology, died suddenly on 24 December 2017 at the age of 89. Dr. Holland, who was affectionately known by her first name, “Jimmie,” had a profound global influence on the fields of Psycho-oncology, Psychosomatic Medicine, and Oncology. Dr. Holland was the Attending Psychiatrist and Wayne E. Chapman Chair at Memorial Sloan-Kettering Cancer Center (MSK) and Professor of Psychiatry, Weill Medical College of Cornell University in New York. In 1977, she was appointed Chief of the Psychiatry Service in the Department of Neurology at MSK. The Psychiatry Service at MSK was the [...]

2018-04-21T11:53:40-07:00February, 2018|OCF In The News, Oral Cancer News|

Suicide Among Cancer Survivors — Highest Risk in HNC

Author: Roxanne Nelson, RN, BSN Source: MedScape.com Date: Feb. 20, 2018 ORLANDO, Florida — Head and neck cancer (HNC) accounts for only about 4% of new cancer cases in the United States, but the risk for suicide among survivors is significantly higher than for survivors of all other cancer types, with the exception of pancreatic cancer. "The risk of suicide is significantly elevated across cancer sites, and the risk is especially high among HNC and pancreatic cancer survivors," said Nosayaba Osazuwa-Peters, BDS, MPH, CHES, instructor, Department of Otolaryngology-Head and Neck Surgery, Saint Louis University School of Medicine, Missouri. "Cancer survivors are candidates for suicide-related psychosocial surveillance," he added. Cancer is the number 2 cause of death in the United States and accounts for 1 of every 4 deaths. Suicide is the tenth cause of death, independent of cancer. "If you add cancer to it, you get the perfect storm," he said. "Survivorship does come at a cost, and this is one of the more unfortunate costs of cancer survivorship," Osazuwa-Peters told delegates here at the Cancer Survivorship Symposium (CSS) Advancing Care and Research. Currently, there are more than 16 million survivors in the United States. The good news is that more people are surviving cancer, and there is now more focus on competing causes of death and comorbidities, he explained. There is also more focus on the increased risk for acute and late toxicities, which needs to be addressed as the rate of survival increases. Osazuwa-Peters pointed out that there [...]

2018-02-27T17:02:46-07:00February, 2018|Oral Cancer News|

Bareback Rider Cody Kiser Uses Tucson Rodeo Role to Rail Against Oral Cancer

Author: Norma Gonzalez Source: Arizona Daily Star Date: Feb. 23, 2018 Prior to Friday’s first event, Cody Kiser stretched and danced around the dressing room behind the chutes. Kiser was nothing but smiles as he loosened up for bareback riding at the 93rd annual La Fiesta de los Vaqueros. While in high school in 2006, Kiser suffered an injury competing in bull riding. The bull stepped on his face, breaking all the bones in its left side. Kiser’s jaw was broken in two places and had to be wired shut. Through plastic surgery, Kiser had his face put back together. Now, Kiser’s smile is more than just a gruesome injury story. The 27-year-old from Carson City became a spokesperson and role model with the Oral Cancer Foundation in 2014, and is the first spokesman to be affiliated with the rodeo. “My side of it isn’t giving out a lot of facts,” he said. “Everyone knows smoking and chewing is bad. If you do it long enough, it’ll kill you.” Kiser has never smoked or chewed. He simply doesn’t like it. “I was never part of that,” Kiser said. “I just like to lead a healthy lifestyle and it just worked out so perfect to get involved with the foundation.” So now, the bareback rider lends his voice to the foundation and helps in the prevention of tobacco use. According to oralcancer.org, as many as 15 percent of high school boys use smokeless tobacco in the United States. The nicotine content in [...]

2018-02-27T10:35:38-07:00February, 2018|Oral Cancer News|

New cancer test isn’t ready for prime time

Author: H Gilbert Welch Date: February 14, 2018 Source: http://www.cnn.com/2018/02/13/opinions/liquid-biopsy-opinion-welch/index.html (CNN)- A simple blood test to detect cancer early. How great is that? There has been enthusiasm about the so-called "liquid biopsy" for years. In mid-January, however, doctors learned more -- both about this vision and its problems. A widely reported study in the journal Science described a liquid biopsy test -- CancerSEEK -- which combined measuring eight tumor biomarkers with testing for pieces of DNA with cancer associated mutations in 16 genes. It's not one test; it's a battery of tests. And while collecting the blood may be simple, the subsequent analysis is extraordinarily complex. The task at hand is particularly challenging. We all have pieces of DNA in our blood. Distinguishing the tumor DNA from the background DNA requires finding the mutations specifically associated with cancer. Adding to the complexity, healthy individuals can have mutations. To avoid labeling innocuous mutations as cancerous requires a bunch of statistical fine-tuning. In other words, there are a lot of steps in a liquid biopsy and much potential for things to go awry. To their credit, the CancerSEEK investigators were very forthright that the study conditions were ideal for the test to accurately detect cancer. The liquid biopsy simply had to discriminate between patients with known cancer (the majority of whom had symptoms) and healthy individuals. And the statistical fine-tuning was tailored to the study participants -- with the knowledge of who had, and who did not have, cancer. Although the test was [...]

2018-02-14T11:36:19-07:00February, 2018|Oral Cancer News|

CDHA Urges Hygienists to Remind Patients of Oral Cancer Screening

Author: Canadian Dental Hygienists Association Date: January 29, 2018 Source: https://www.oralhealthgroup.com World Cancer Day (February 4) is a perfect time for dental hygienists across Canada to remind the public of the importance of regular oral cancer screenings, not only during dental appointments, but also now at home. The Canadian Cancer Society projected in 2017 that 4,700 Canadians would be diagnosed with oral cavity cancer, and that 1,250 Canadians would die.  In hopes of improving the long-term outcomes for people diagnosed with oral cancer, the Canadian Dental Hygienists Association (CDHA) has partnered with the Oral Cancer Foundation and the American Dental Hygienists Association on a “Check Your Mouth™” initiative to help individuals identify the early signs and symptoms of oral cavity cancers.  “Dental hygienists recognize that early detection has great potential to reduce the oral cancer burden in Canada,” states Sophia Baltzis, CDHA president. “Between dental visits, which usually include an oral cancer screening, our clients can and should examine their mouths for suspicious tissue changes.” The Check Your Mouth™ campaign features an interactive website (www.checkyourmouth.org) that offers easy-to-use tools and tips for a quick visual and tactile examination of the oral cavity.  Individuals can learn to self-discover the early symptoms of disease and then seek further evaluation from a dental professional if necessary.  “Dental hygienists are your partners in prevention,” adds Baltzis. “We encourage all Canadians to maintain a healthy lifestyle, practice good oral hygiene habits, and spot the early signs of oral cancer. The Check Your Mouth™ website is a valuable [...]

2018-02-06T14:57:40-07:00January, 2018|Oral Cancer News|

Study Identifies Potential Cause of Hearing Loss from Cisplatin

Author: NCI Staff Date: January 26, 2018 Source: National Cancer Institute (https://www.cancer.gov/news-events) Results from a new study may explain why many patients treated with the chemotherapy drug cisplatin develop lasting hearing loss. Researchers found that, in both mice and humans, cisplatin can be found in the cochlea—the part of the inner ear that enables hearing—months and even years after treatment. By contrast, the drug is eliminated from most organs in the body within days to weeks after being administered. The study, led by researchers from the National Institute on Deafness and other Communication Disorders (NIDCD), part of the National Institutes of Health, was published November 21 in Nature Communications. Cisplatin, a platinum-based chemotherapy drug, is commonly used for the treatment of many cancers, including bladder, ovarian, and testicular cancers. But cisplatin and other similar platinum-containing drugs can damage the cochlea, leaving 40%–80% of adults, and at least 50% of children, with significant permanent hearing loss, a condition that can greatly affect quality of life. “This study starts to explain why patients who receive the drug sustain hearing loss,” said Percy Ivy, M.D., associate chief of NCI’s Investigational Drug Branch, who was not involved in the study. “This is very important, because as we come to understand how cisplatin-related hearing loss occurs, over time we may figure out a way to block it, or at least diminish its effects.” A New Approach to Researching Cisplatin-Induced Hearing Loss The new study differs from previous research because it is a comprehensive look at the pharmacokinetics, or concentration, of the [...]

2018-02-06T14:57:52-07:00January, 2018|Oral Cancer News|

Anti-smoking plan may kill cigarettes–and save Big Tobacco

Date: January 19, 2018 Author: Matthew Perrone Source: www.apnews.com WASHINGTON (AP) — Imagine if cigarettes were no longer addictive and smoking itself became almost obsolete; only a tiny segment of Americans still lit up. That’s the goal of an unprecedented anti-smoking plan being carefully fashioned by U.S. health officials. But the proposal from the Food and Drug Administration could have another unexpected effect: opening the door for companies to sell a new generation of alternative tobacco products, allowing the industry to survive — even thrive — for generations to come. The plan puts the FDA at the center of a long-standing debate over so-called “reduced-risk” products, such as e-cigarettes, and whether they should have a role in anti-smoking efforts, which have long focused exclusively on getting smokers to quit. “This is the single most controversial — and frankly, divisive — issue I’ve seen in my 40 years studying tobacco control policy,” said Kenneth Warner, professor emeritus at University of Michigan’s school of public health. The FDA plan is two-fold: drastically cut nicotine levels in cigarettes so that they are essentially non-addictive. For those who can’t or won’t quit, allow lower-risk products that deliver nicotine without the deadly effects of traditional cigarettes.   US health officials are pushing ahead with an unprecedented plan to make cigarettes less addictive and provide lower-risk alternative products to US smokers. (Jan. 19) This month the government effort is poised to take off. The FDA is expected to soon begin what will likely be a years-long process [...]

2018-02-06T14:58:15-07:00January, 2018|Oral Cancer News|

HPV vaccine is safe, effective after 10 years: study

Author: AFP/RelaxNews Date: November 30, 2017 Source: Globalnews.ca New research looking into the long-term effects of the human papillomavirus (HPV) vaccine has found it to be both safe and effective in protecting against the most virulent strains of the virus. Led by Dr. Daron G. Ferris, professor in the Department of Obstetrics and Gynecology at the Medical College of Georgia and at the Georgia Cancer Center at Augusta University, the study is the longest followup to date on the vaccine, looking at data from 1,661 male and female participants who were followed for just under 10 years. Of these participants, around two-thirds received a three-dose regimen of the vaccine when they were ages nine to 15 and sexually inactive. Initially about one-third received a placebo — not a vaccine — however, the placebo group also received the vaccine 30 months into the study, meaning that these individuals were followed a shorter period of time. Ferris found that the vaccine was virtually 100 per cent effective in preventing the disease, although vaccinating earlier produced the most robust initial and long-term antibody response, the proteins found in the blood which help fight infection. “We needed to answer questions like if we vaccinate earlier in life, will it last,” explained Ferris, “The answer is yes, this cancer prevention vaccine is working incredibly well 10 years later. A booster vaccine likely will not be needed by these young people. I think now we have come full circle.” The new finding also supports previous research which suggests that [...]

2017-12-03T14:03:35-07:00November, 2017|Oral Cancer News|

10 Facts Everyone Should Know About HPV

Author: Lindsay Holmes Date: November 27, 2017 Source: Huffingtonpost.com First thing: Don't stress. An HPV diagnosis from your doctor doesn't have to be scary. In the first season of HBO’s “Girls,” Lena Dunham’s character, Hannah, gets a startling wake-up call when she tests positive for the human papillomavirus. She gets upset and confronts her ex-boyfriend about it. Her best friend tells her “all adventurous women” have HPV, but she generally buys into the overblown idea that her life is over. Diagnoses like HPV can be complicated, and also unfairly laden with stigma. Research shows that shame and fear surrounding sexual health issues can be a barrier to testing and management. But it doesn’t have to be this way. Experts say that educating yourself can help take the scariness out of an HPV diagnosis and help you manage your health. Below is a breakdown of the facts everyone ― yes, including men! ― should know about HPV: HPV IS INCREDIBLY COMMON. Approximately 79 million Americans have HPV, according to the U.S. Centers for Disease Control and Prevention. Most of those infected are in their 20s. “HPV is very common, and most people will be exposed to HPV at some time in their lives,” Dr. Grace Lau, an assistant professor in the Department of Obstetrics and Gynecology at NYU Langone Health, told HuffPost. HPV IS CONSIDERED A SEXUALLY TRANSMITTED INFECTION. It’s the most common one, according to the CDC. It’s typically spread through vaginal or anal sex, and it can be passed [...]

2017-12-03T14:03:50-07:00November, 2017|Oral Cancer News|

Superseed? Apricot kernels, touted as cancer cure, linked to cyanide poisoning

Author: Catherine Solyom Date: November 22, 2017 Source: flipboard.com Brendan Brogan had just returned from a shopping trip on the Plateau laden with exotic snacks. On a visit to Montreal from California, he stood in the doorway of his buddy Mike Guetta’s room, munching away on something as they discussed the absurdities of the day. Then Guetta looked up. “Those better not be almonds,” he said. “You know I’m allergic to those.” “No, no,” Brogan replied, “I would never do that. These are apricot pits.” “What?!? Don’t eat those! They’re poisonous!” Brogan pooh-poohed the warning, arguing the kernels were organic and he’d bought them at the health food store. “Look! It’s the superseed of the Hunza people, with Vitamin B17!” Then he turned the bag over and read the fine print. His face went grey: “Caution: Do not consume more than 2-3 kernels per day. Keep out of the reach of children. Pregnant and nursing women should not consume apricot kernels. Health Canada warns that eating too many apricot kernels can lead to acute cyanide poisoning.” After a quick call to poison control, Brogan rushed to the nearest emergency room. He had eaten a third of the bag. Apricot kernels, like cherry pits and apple seeds, contain a product called amygdalin, also known as laetrile and marketed as Vitamin B17. Bitter apricot kernels — the pits of the pits — are widely available in Montreal health food stores, including at Rachelle-Béry branches across the city, where Brogan bought some. They are [...]

2018-02-06T14:58:38-07:00November, 2017|Oral Cancer News|
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