A man’s cancer vanished after he was injected with a weakened herpes virus in a promising clinical trial
Source: www.insider.com Author: Andrea Michelson A new cancer therapy that uses a modified herpes virus to attack tumor cells showed promise in early clinical trials abroad. The drug, called RP2, completely obliterated one patient's oral cancer. The 39-year-old told the BBC that he had cancer of the salivary glands, which continued to grow despite attempts at treatment. He was preparing for the end of his life when he learned about the experimental drug, which was available through a phase one safety trial at the Institute of Cancer Research in the UK. After a short course of the drug, the patient — Krzysztof Wojkowski of west London — has been cancer-free for two years and counting, he told the BBC. Other patients in the trial saw their tumors shrink, although the majority did not have a significant change: three out of nine patients who were given the trial drug alone, and seven of 30 who received a combined treatment, appeared to benefit from the experimental therapy. While more research needs to be done to see how RP2 compares to known therapies, the drug seemed to help some patients and only caused mild side effects, such as tiredness. These early results are promising, said Jonathan Zager of the Moffitt Cancer Center, who was not involved in the trial. "We'll see some more studies done in the very near future, and I'm excited — certainly not disheartened or skeptical," Zager told Insider. A modified virus delivers a 'one-two punch' to cancer cells The [...]