New technology that transforms brain signals into speech may give voice to people with Parkinson’s, throat cancer

Source: www.techtimes.com Author: Naia Carlos Tech Times Technology has advanced so greatly that even patients who have completely lost their voice could potentially have it restored soon. In fact, scientists have already developed a computer-based system that can translate brain activity into speech. Someday in the future, this system could help individuals who have lost their speech through various conditions, such as Parkinson's disease, throat cancer, and paralysis. "Speech is an amazing form of communication that has evolved over thousands of years to be very efficient," said Edward F. Chang, M.D., senior author of the study and professor of neurological surgery at the University of California, San Francisco. "Many of us take for granted how easy it is to speak, which is why losing that ability can be so devastating. It is our hope that this approach will be helpful to people whose muscles enabling audible speech are paralyzed." Scientists Develop Computer-Generated Speech Translator In a study published in the journal Nature, researchers shared the details of their new technology. First, the team collected recordings of the brain activity of epilepsy patients without speech problems and who are scheduled to undergo surgery. The researchers had each patient speak or mime in full sentences, then they constructed maps on how the brain directs the entire vocal system to make sounds. The second step involved the maps getting applied to a computer program that produced the speech. Volunteers listened to the computer-generated speech and asked to transcribe what they heard. In more [...]

Cancer ‘vaccine’ shown to be effective in small trial

Source: www.upi.com Author: Dennis Thompson, HealthDay News A new method of brewing a cancer vaccine inside a patient's tumor could harness the power of the immune system to destroy the disease, researchers report. Immune stimulants are injected directly into a tumor, which teaches the immune system to recognize and destroy all similar cancer cells throughout the body, said senior researcher Dr. Joshua Brody. He is director of the Lymphoma Immunotherapy Program at the Icahn School of Medicine at Mount Sinai in New York City. "We're injecting two immune stimulants right into one single tumor," Brody said. "We inject one tumor and we see all of the other tumors just melt away." Eight out of 11 lymphoma patients in a small, early clinical trial experienced partial or complete destruction of the tumor that received the initial injection, according to the report published April 8 in the journal Nature Medicine. The vaccine also halted overall cancer progression in six patients for three to 18 months, and caused significant regression or actual remission in three patients, the investigators found. The results were solid enough that the research team is expanding its next clinical trial to include lymphoma, breast, and head and neck cancer patients, Brody said. That trial started in March. Prior efforts at unleashing the immune system to fight cancer have focused on T-cells, which Brody calls the "soldiers" of the immune army because they directly attack harmful invaders in the body. Drugs called checkpoint inhibitors help T-cells identify cancer cells as [...]

How does alcohol compare with tobacco in terms of cancer risk?

Source: rocklandregister.com Author: Rockland Staff Everyone knows, these days, about the cancer risks associated with smoking cigarettes. Perhaps not as many understand that drinking alcohol also poses some elevated risk for developing cancer. A new study, however, has compared and quantified these risks in a new report suggesting that drinking a single bottle of wine per week can bear the equivalent cancer risk of at least five cigarettes. Study author Dr. Theresa Hydes comments, “It is well-established that heavy drinking is linked to cancer of the mouth, throat, voice box, gullet, bowel, liver, and breast. Yet, in contrast to smoking, this is not widely understood by the public.” According to the National Cancer Institute, data shows there are “clear patterns” related to alcohol consumption and the development of several types of cancer: liver cancer, colorectal cancer, esophageal cancer, breast cancer, and head and neck cancer. Essentially, the more you drink (both acutely and cumulatively), the higher your risk for developing cancer. However, the study also suggest that even very light drinks (one or fewer drinks per day, or up to 7 per week) have about the same moderately elevated risk as binge drinkers (sporadic drinking of at least four servings in one session). From this data, then, a British team of researchers from University of Southampton, Bangor University, and the University Hospital Southampton NHS Foundation Trust investigated the data, particularly in how alcohol consumption might compare against smoking. Analyzing data taken from Cancer Research UK—regarding lifetime cancer risk across the [...]

April is Oral Cancer Awareness Month: Self-exams, early detection can save lives

Source: www.prnewswire.com Author: press release Because early detection of oral cancer offers a greater chance of a cure, the American Association of Oral and Maxillofacial Surgeons (AAOMS) is reminding the public during Oral Cancer Awareness Month of the importance of performing monthly self-exams. AAOMS promotes self-exams and screenings every April with the Oral Cancer Foundation, which predicts about 53,000 new cases of oral cancer will be diagnosed in 2019 in the United States – leading to more than 9,000 deaths. "A monthly self-exam takes only minutes and could potentially save your life," said AAOMS President A. Thomas Indresano, DMD, FACS. "If done on a regular basis, you're increasing the chances of identifying changes or new growths early. The survival rate for oral cancer is between 80 and 90 percent when it's found at early stages of development." Oral and maxillofacial surgeons (OMSs) encourage a six-step oral cancer self-exam that involves looking and feeling inside the mouth for suspicious sores and feeling the jaw and neck for lumps. Using a bright light and a mirror: First remove any dentures. Look and feel inside the lips and the front of the gums. Tilt the head back to inspect and feel the roof of the mouth. Pull the cheek out to inspect it and the gums in the back. Pull out the tongue and look at its top and bottom. Feel for lumps or enlarged lymph nodes in both sides of the neck, including under the lower jaws. Oral cancer symptoms may include [...]

The HPV Vaccine Is Already Dramatically Lowering Rates of Cervical Disease

Source: Gizmodo Date: 04/03/19 Author: Ed Cara A new study out Wednesday in the BMJ is the latest to showcase even the short-term benefits of the human papillomavirus (HPV) vaccine. It found that the routine vaccination of preteen girls in Scotland, starting in 2008, led to drastically lower rates of cervical disease by the time the girls turned 20. That included conditions known to raise the risk of cervical cancer later on in life. There are over 100 different types of HPV that regularly infect humans. Most types cause no symptoms at all, while some can cause annoying but harmless warts on our hands, feet, or genitals, depending on where they like to call home. High-risk HPV types, however, linger in the cells that line the surfaces of our body, triggering changes that can eventually turn them cancerous. These HPV types account for nearly all cases of cervical cancer, as well as a substantial proportion of cancers in the mouth, throat, anus, and penis. We’ve had a vaccine available for two of the most common high-risk types of HPV since 2006, when it was at first recommended only for teen girls. Over the years, the window of opportunity for getting the vaccine has expanded, as has the number of HPV types it protects against. The newest version protects against seven high-risk types that account for 90 percent of cervical cancers (along with two types that cause genital warts). And young boys and men are now also encouraged to get the vaccine, as are women up [...]

2019-04-04T09:26:20-07:00April, 2019|Oral Cancer News|

Flossing and going to the dentist linked to lower risk of oral cancer

Source: www.livescience.com Author: Yasemin Saplakoglu, Staff Writer Regularly flossing and going to the dentist may be tied to a lower risk of oral cancer. That's according to findings presented March 31, here at the American Association for Cancer Research (AACR) annual meeting. In the new study, researchers analyzed the dental health behaviors of patients who were diagnosed with oral cancer between 2011 and 2014 at the ear, nose and throat clinic at The Ohio State University Comprehensive Cancer Center. The patients' behaviors were compared to those of non-cancer patients who came to the clinic for other reasons, such as dizziness or an earache. [7 Odd Things That Raise Your Risk of Cancer (and 1 That Doesn't)] All of the patients in the study had responded to a survey that included questions about how often they flossed, how often they went to the dentist, how sexually active they were and if they smoked or drank alcohol. Oral cancer can be divided into two categories: those driven by the sexually transmitted human papillomavirus (HPV) and those that aren't, said lead study author Jitesh Shewale, a postdoctoral fellow at the University of Texas MD Anderson Cancer Center in Houston. (Smoking and drinking are both risk factors for non-HPV oral cancers.) After adjusting for factors such as age, gender, socioeconomic status and race, the researchers found that oral HPV-negative people who went to the dentist less than once a year had nearly twice the risk of developing oral cancer than those who went once [...]

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