A Look at Therapy Toxicities & Biology in Head & Neck Cancers

Source: journals.lww.com Author: Valerie Neff Newitt A measure of intrigue and discovery pertaining to head and neck cancer, spiked with compassion for patients struggling against treatment toxicities, helps quench the intellectual thirst of Yvonne Mowery, MD, PhD, Butler Harris Assistant Professor of Radiation Oncology at Duke University Medical Center, Durham, N.C. Splitting time between the clinic and laboratory, Mowery is actively engaged in patient care as well as preclinical, translational, and clinical research. “I hope to get a better understanding of the biology of head and neck cancer and determine pathways that we can target to reduce metastatic spread of the disease and improve responsiveness to available treatments,” she told Oncology Times. Long before reaching her current status as an award-winning investigator, Mowery grew up in Richmond, Va., in the midst of a “completely non-scientific” family. “I was an oddball,” she joked, while recalling her parents' patience with her backyard composting experiments that became so foul-smelling that the health department was contacted. As a kid, her idea of a great present was an encyclopedia of science, and the thing that caught her eye at the toy store was a junior chemistry set. Science was clearly her path when she headed to the University of Virginia. In her sophomore year, Mowery began working in a genetics lab. That's where the lure of fruit flies took hold. “I looked at the development of their reproductive system and found that very interesting,” she recalled. Nearing the completion of her undergraduate education, Mowery debated [...]

2018-11-04T07:47:45-07:00November, 2018|Oral Cancer News|

Forms of tobacco that give you cancer

Source: www.medicalnewstoday.com Author: Zawn Villines, reviewed by Philip Gregory, PharmD, MS Nicotine is the primary substance in cigarettes that causes addiction, but most experts agree that it does not directly cause cancer. Most research points to cigarette smoke, not nicotine, as being the primary contributor to cancer among smokers. However, although most experts agree that nicotine does not directly cause cancer, some research suggests that nicotine may lead to a type of DNA damage that increases the risk of cancer. Research from 2015 reported in the Indian Journal of Medical and Paediatric Oncology suggests that nicotine may increase the risk of cancer because it might damage DNA, initiate cancer and cause it to progress faster, and interact with cancer-causing chemicals. Research into the role of nicotine in cancer is ongoing. Many studies, however, do not differentiate between nicotine, tobacco, or smoking when they discuss cancer risk. This makes it difficult to determine which of them causes cancer. Even if nicotine does cause or lead to cancer, the risks of developing cancer through the use of nicotine-only products are much lower than the risks from smoking. Methods of consuming nicotine and their safety Nicotine is addictive and is the primary reason most people smoke. However, almost every other nicotine-based product is safer than smoking. No nicotine replacement product is completely safe for all people, but some of the less harmful alternatives include: Nicotine replacement therapy A person with a heart condition should speak to a doctor before undergoing NRT. Nicotine replacement [...]

2018-11-01T07:55:23-07:00November, 2018|Oral Cancer News|
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