2015 – Page 10 – Oral Cancer News

The case for extending the HPV vaccine is clear and urgent

Source: www.huffingtonpost.co.uk Author: Dr Shaun Griffin Last month the world marked Immunization Week, an opportunity to raise awareness about the importance of routine life-saving immunizations and how they have transformed our approach to public health over the course of centuries. Close the Immunization Gap was this year's theme by the World Health Organisation. Progress towards global vaccination targets for 2015 is far off-track, according to the WHO one in five children still miss out on routine life-saving immunizations that could avert 1.5 million deaths each year from preventable diseases. The immunization gap also extends to gender, age and sexuality. A vaccination programme against the human papillomavirus (HPV) began in 2008 in the UK for girls aged 12-13 to reduce their risk of developing cervical cancer, which is caused by HPV. However, emerging research over the past eight years has found that cancers of the head, mouth, throat, penis and anus can also be caused by strains of the virus. The incidence rate of anal cancer in men who have sex with men (MSM) is increasing. Anal cancer incidence rates in MSM are equivalent to the rates that existed for cervical cancer in women before 1988, when the Government introduced the cervical cancer screening programme. Cancer Research UK (CRUK) estimated incidence rate of anal cancer is 78 per 100,000 per year in HIV-positive MSMs who are on HAART (anti-retroviral treatment), compared with 5 per 100,000 per year in HIV-negative MSMs. Around 5,500 men were diagnosed with oral, penile or anal cancer [...]

Oral Cancer Foundation News Team - A2015-05-06T14:07:25-07:00May, 2015|Oral Cancer News|

Laser Treatment Halts Oral Mucositis in Its Tracks

Source: www.medscape.com Author: Fran Lowry Spa-like treatment with a cool, low-level laser, similar to that use for wrinkles, vanquishes oral mucositis, one of the most debilitating toxicities of cancer therapy. "I have been an oncology nurse for over 25 years, and in those 25 years, there has been nothing that helps prevent or is effective against the treatment for oral mucositis, until now," said Annette Quinn, RN, MSN, from the University of Pittsburgh Cancer Institute. "Patients say they rank it higher than nausea and vomiting when it comes to adverse side effects, especially because we have good medications to control nausea and vomiting. But the low-level laser works better than we could have hoped," Quinn told Medscape Medical News. She presented results from a pilot project at the Oncology Nursing Society (ONS) 40th Annual Congress in Orlando, Florida. Oral mucositis affects virtually all head and neck cancer patients undergoing chemo and radiation therapy, and about 75% to 100% of patients undergoing stem cell transplantation with whole-body irradiation experience some degree of oral mucositis. Low-level laser therapy (LLLT) has been used to treat oral mucositis for a decade in Europe and South America, but it has not made its way to the United States because there is no mechanism for reimbursement, Quinn reported. She hopes this study will change that. "Reimbursement is the main obstacle to its use in the United States, but for this study, I was able to secure the treatment [...]

Charlotte Parker2015-05-04T10:29:44-07:00May, 2015|Oral Cancer News|

Three things you might not know about HPV

Source: www.huffingtonpost.ca Author: Sunnybrook Health Sciences Centre April 26 to May 2 is National Immunization Awareness week in Canada. One immunization known for raising a lot of questions is the Human Papillomavirus (HPV) vaccination, provided free of charge in Ontario to girls in grades 8-12, and following provincial schedules across the country. While there is lots of information online, at school and at the doctor's office about HPV, there is still a lot of confusion about what it may mean for your loved ones. Dr. Nancy Durand, gynecologist at Sunnybrook, explains three little-known facts about HPV. 1) HPV causes cancer in men, too When Michael Douglas candidly revealed his oral cancer was caused by HPV, many people expressed surprise. Even though HPV has traditionally been thought of as a disease that affects women and mainly causes cervical cancer, men are actually at higher risk of being diagnosed with certain types of HPV-positive cancers than women. "It's not well understood why men are at higher risk for HPV-positive oral cancer, but it does point out that vaccination in men is even more important than we may have previously thought," says Dr. Durand. Physicians are learning more and more that HPV can also cause other cancers in both women and men, such as anal cancers and head & neck cancers (cancers of the base of the tongue, tonsils and soft palate). 2) Not all HPV infections lead to cancer You've probably read some of the (slightly scary) statistics about HPV: Three in [...]

Oral Cancer Foundation News Team - A2015-04-29T13:19:58-07:00April, 2015|Oral Cancer News|

U-M scientists observe deadly dance between nerves and cancer cells

Source: ns.umich.edu Author: Laura Bailey In certain types of cancer, nerves and cancer cells enter an often lethal and intricate waltz where cancer cells and nerves move toward one another and eventually engage in such a way that the cancer cells enter the nerves. The fluorescence image shows the interaction between the nerve (red) and cancer (green). Image credit: Nisha D’Silva The findings, appearing in Nature Communications, challenge conventional wisdom about perineural invasion, which holds that cancer cells are marauders that invade nerves through the path of least resistance, said Nisha D'Silva, principal investigator and professor at the University of Michigan School of Dentistry. D'Silva's lab discovered that perineural invasion is actually a much more intricately choreographed biochemical give-and-take between the nerves and the cancer cells. "Once head and neck cancer invades the nerves, it is one of the worst things that can happen," said D'Silva, who also has a joint appointment at the U-M Medical School Department of Pathology and is a member of the U-M Cancer Center's Head and Neck Oncology program. "It is highly correlated with poor patient survival, and there is no targeted treatment for it because it is not known why some tumors do this and some don't." Perineural invasion is seen most in head and neck, pancreatic, stomach and colon cancers, and causes severe pain or numbness, tumor spread and recurrence, and loss of function, among other complications. D'Silva's lab found that perineural invasion begins when the nerve releases a stimulus that triggers a [...]

Oral Cancer Foundation News Team - A2015-04-29T13:13:53-07:00April, 2015|Oral Cancer News|

Double the N.I.H. Budget

Source: NYTimes.comAuthor: Newt Gingrich MCLEAN, Va. — NO one who lived through the 1990s would have suspected that one day people would look back on the period as a golden age of bipartisan cooperation. But in some important ways, it was. Amid the policy fights that followed the Republican victories of 1994, President Bill Clinton and the new majorities in Congress reached one particularly good deal: doubling the budget for the National Institutes of Health. The decision was bipartisan, because health is both a moral and financial issue. Government spends more on health care than any other area. Taxpayers spend more than $1 trillion a year for Medicare and Medicaid alone, and even more when you add in programs like Veterans Affairs, the Children’s Health Insurance Program and the Indian Health Service. Unfortunately, since the end of the five-year effort that roughly doubled the N.I.H. budget by 2003, funding for the institutes has been flat. The N.I.H. budget (about $30 billion last year) has effectively been reduced by more than 20 percent since then. As 92 percent of the N.I.H. budget goes directly to research, one result is that the institutes awarded 12.5 percent fewer grants last year than in 2003. Grant applications, over the same period, increased by almost 50 percent. Even as we’ve let financing for basic scientific and medical research stagnate, government spending on health care has grown significantly. That should trouble every fiscal conservative. As a conservative myself, I’m often skeptical of government “investments.” But when it comes [...]

Charlotte Parker2015-04-22T10:25:13-07:00April, 2015|Oral Cancer News|

LED Dental Joins With the Oral Cancer Foundation to promote oral cancer early detection initiative

Source: www.marketwatch.com Author: press release LED Dental Inc. has announced that the company will be serving as a strategic partner in the Oral Cancer Foundation's "Be Part of the Change"(TM) program, seeking to promote the importance of routine comprehensive oral screenings and early detection in the fight against oral cancer. The Oral Cancer Foundation initiated the "Be Part of the Change"(TM) campaign to help promote a shift in paradigm with regard to the screening for oral cancer, creating a movement toward earlier detection of oral disease. While regular oral screenings are a key tool in the early detection of oral cancer and pre-cancerous lesions, many patients are not receiving routine oral examinations that could potentially locate a serious oral health concern. The Oral Cancer Foundation is working to change the mindset of the oral healthcare industry, making improved oral screening protocols a priority in every dental practice. "The best defense any patient has against oral disease and oral cancer is early detection, which is where dental practitioners can effect change," said Brian Hill, founder and executive director of the Oral Cancer Foundation. "When oral cancer is located in earlier stages, there is higher probability for reduced treatment related morbidity and improved patient outcomes. Our goal is to get healthcare professionals to commit to performing routine comprehensive oral examinations on every patient, especially during hygiene visits and recall appointments." As the manufacturer of the market-leading VELscope® Vx Enhanced Oral Assessment, LED Dental has joined the Oral Cancer Foundation's cause, providing a free [...]

Oral Cancer Foundation News Team - A2015-05-18T22:22:16-07:00April, 2015|OCF In The News, Oral Cancer News|

Broccoli may prevent oral cancer as clinical tests set to start on humans

Source: www.mirror.co.uk Author: staff The much-maligned green vegetable deserves more respect as lab tests show extracts of sulforaphane reduced tumours in mice. Broccoli could soon protect people from cancer of the mouth, throat, neck and head in a new treatment known as “green chemoprevention.” Cruciferous vegetables such as broccoli, cabbage and garden cress have a high concentration of sulforaphane. Previous studies, including large-scale trials in China, have shown sulforaphane helps mitigate the effects of environmental carcinogens. Now lab tests have shown extracts made from broccoli sprout protected mice against oral cancer. American scientists now plan to carry out clinical trial on patients at high risk of a recurrence of head and neck cancer. They will be given capsules containing broccoli seed powder to determine if they can tolerate the regimen and whether it has enough of an impact on their oral lining to prevent cancer. Associate professor Dr Julie Bauman of the University of Pittsburgh said: “People who are cured of head and neck cancer are still at very high risk for a second cancer in their mouth or throat, and, unfortunately, these second cancers are commonly fatal. “So we’re developing a safe, natural molecule found in cruciferous vegetables to protect the oral lining where these cancers form.” The study involved testing sulforaphane in the laboratory when over several months mice predisposed to oral cancer were given the extract and found that it significantly reduced the incidence and number of tumours. Professor of medicine Dr Daniel Johnson at Pitt’s School [...]

Oral Cancer Foundation News Team - A2015-04-20T06:51:10-07:00April, 2015|Oral Cancer News|

HPV Shots for Boys Might Cut Cancer Costs

Source: MedPageToday.comAuthor: Charles Bankhead - Canadian study suggests vaccination would save money by preventing oropharyngeal cancer. Widespread vaccination of boys against human papillomavirus (HPV) infection proved to be a cost-saving approach to prevent subsequent head and neck cancer, according to data based on the Canadian health system. A 70% immunization rate and 99% efficacy with the quadrivalent vaccine Gardasil might reduce costs by as much as $28 million ($22.2 million U.S.). Reducing uptake and efficacy to 50% still might save $8 million ($6.35 million U.S.), Lillian L. Siu, MD, of Princess Margaret Cancer Center in Toronto, and co-authors reported online in Cancer. "According to the findings of this preliminary analysis, HPV vaccination for boys aged 12 years may be a cost-effective strategy in relation to the prevention of oropharyngeal cancer alone, strengthening the cost-effectiveness of a male vaccination program," the authors concluded. "The argument for funding male HPV vaccination in North America is becoming more compelling given the benefits of reductions in genital warts and anal cancer and the potential benefits for the female population because of increased herd immunity. "Prospective data collection for male HPV vaccination and oropharyngeal cancer may validate these findings in the future." The data are consistent with other studies showing cancer benefits for HPV immunization, although the Canadians are the first to suggest that vaccination saves money, U.S. sources told MedPage Today. Background Initial clinical studies of HPV vaccination and national vaccination programs targeted girls and young women. Only recently has the focus expanded to include immunization of adolescent boys. [...]

Charlotte Parker2015-04-14T10:42:30-07:00April, 2015|Oral Cancer News|

Legal loopholes allow big tobacco companies to target young children with new products

Source: http://www.contracostatimes.comAuthor: Sen. Mark Leno & Tony Thurmond With smoking now widely known as the nation's No. 1 preventable killer, Big Tobacco is targeting our kids with new products that give an illusion of more safety but carry the age-old motive to hook kids on tobacco at a young age. Preventing children from picking up nicotine addiction is the best way to keep them free of tobacco-related disease for life. That's why we've each introduced bills that seek to curb youth usage of smokeless (chewing) tobacco and e-cigarettes. Last year, many were shocked when Hall of Famer Tony Gwynn, who played for the San Diego Padres, died from cancer of the salivary glands that was related to decades of smokeless tobacco usage. Former World Series hero Curt Schilling, who helped propel the Arizona Diamondbacks and Boston Red Sox to championships, has blamed his bout with mouth cancer on chewing tobacco. Use of chewing tobacco by professional athletes sends the wrong message to our kids, but nonetheless a powerful one. Researchers at the Harvard School of Public Health have found that the use of smokeless tobacco by players has a powerful "role model effect" on youths, particularly young males. It's no wonder then that while overall rates of smoking have declined thanks to several decades of intense educational programs, smokeless tobacco rates have remained stubbornly high among youth. One in every 6 high school boys report regular usage. Assembly Bill 768 bans smokeless tobacco at all ballparks in California with organized baseball, [...]

Charlotte Parker2015-04-13T12:22:32-07:00April, 2015|Oral Cancer News|

Breath test for detecting head and neck cancer

Source: http://medicalxpress.com/ Author: provided by Ecole Polytechnique Federale de Lausanne A portable device can detect the presence of certain types of cancer in people's breath. Tested on patients, the new device was developed in part by EPFL researchers as part of an international collaboration. Inhale, then exhale. This simple act could now save lives. A technology developed in part at EPFL can quickly identify the presence of a head and neck cancer, such as of the throat or mouth by analysing people's breath. The new device, equipped with extremely sensitive sensors, has been tested on patients and operates with a computer or even a mobile phone. It's an innovative tool for the early diagnosis of tumours. Very few routine exams exist to detect cancer. Yet this disease is the third leading cause of death worldwide. Most tumours are found relatively late, which makes recovery less likely. Cancer "signals" its presence in human breath At SAMLAB in Neuchâtel, under the direction of Nico de Rooij, a team of researchers including Frédéric Loizeau, a doctoral student at the time, developed very precise micro-sensors able to distinguish the breath of a healthy patient from that of a sick one. The scientists' starting point was the observation that human breath contains not only air, but also hundreds of volatile organic compounds (VOCs) whose presence and concentration vary depending on the patients' state of health. The metabolism of cancerous cells is different from that of healthy cells, and the two types of cells produce different [...]

Oral Cancer Foundation News Team - A2015-04-12T07:41:10-07:00April, 2015|Oral Cancer News|