Monitoring Tobacco-Specific N-Nitrosamines and Nicotine in Novel Marlboro and Camel Smokeless Tobacco Products: Findings From Round 1 of the New Product Watch

Source: Abstract Introduction: Information on chemical composition of the new oral “spitless” smokeless tobacco products is scarce, and it is not clear whether there is some variability as a function of purchase place or time due to either unintended or intended manufacturing variations or other conditions. Methods: We analyzed tobacco-specific N-nitrosamines (TSNA) and nicotine in Marlboro Snus, Camel Snus, and dissolvable Camel products Orbs, Sticks, and Strips that were purchased in various regions of the country during the summer of 2010. Results: A total of 117 samples were received from different states representing six regions of the country. Levels of unprotonated nicotine in Marlboro Snus and Camel Snus varied significantly by regions, with the differences between the highest and the lowest average regional levels being relatively small in Marlboro Snus (∼1.3-fold) and large in Camel Snus (∼3-fold). Some regional variations in TSNA levels were also observed. Overall, Camel Snus had significantly higher TSNA levels than Marlboro Snus, and Camel Strips had the lowest TSNA levels among all novel products analyzed here. The amount of unprotonated nicotine in the dissolvable Camel products was comparable to the levels found in Marlboro Snus. Conclusions: Our study demonstrates some regional variations in the levels of nicotine and TSNA in Marlboro and Camel novel smokeless tobacco products. Continued monitoring of this category of products is needed as the existing products are being test marketed and modified, and new products are being introduced. This information is particularly important given its relevance to Food and Drug [...]

Kentucky Cancer Center Urges Smokers to Switch to Smoke-Free Tobacco. But is it Really a Better Option?

Source: In the smoker-heavy state of Kentucky, a cancer center is suggesting something that most health experts won't and the tobacco industry can't: If you really want to quit, switch to smoke-free tobacco. The James Graham Brown Cancer Center and the University of Louisville are aiming their "Switch and Quit" campaign at the city of Owensboro. It uses print, radio, billboard and other advertising to urge smokers to swap their cigarettes for smokeless tobacco and other products that do not deliver nicotine by smoke. Supporters say smokers who switch are more likely to give up cigarettes than those who use other methods such as nicotine patches, and that smokeless tobacco carries less risk of disease than cigarettes do. "We need something that works better than what we have," said Dr. Donald Miller, an oncologist and director of the James Graham Brown Cancer Center, which supports the effort along with the University of Louisville. "This is as reasonable a scientific hypothesis as anybody has come up with and it needs to be tried." The campaign runs counter to the prevailing opinion of the public health community, which holds that there is no safe way to use tobacco. Federal researchers, however, have begun to at least consider the idea that smokers might be better off going smokeless. The National Cancer Institute at the National Institutes of Health says on its website that the use of all tobacco products "should be strongly discouraged," and that there is "no scientific evidence that using [...]

Packet Helps Smokers Hide Graphic Warnings

Source: Sticky seals in the packets of one brand of cigarettes are helping smokers cover up graphic health warnings. Graphic images of illnesses like gangrene, mouth cancer and lung disease must be printed on every packet of cigarettes to cover 30% of the front and 90% of the back of the pack. ONE News looked at a range of cigarettes from a number of companies. Dunhill was the only product found with a seal inside the packet that can be stuck on the outside. It is labelled "exclusively Dunhill". The sticky 'reloc' seal is just the size to cover health warnings. Michael Colhoun of Action on Smoking and Health says nothing about a tobacco packet is accidental and the sticky seals have been included deliberately. "This seems to be a brand marketing exercise," he said. Fresh-seal stickers are used to cover graphic warning images Manufacturer British American Tobacco says its design is not intended to undermine the law. "We do not condone the practice of using one part of the pack designed for a particular purpose to hide those warnings," the company said. It said the seal is simply for keeping cigarettes fresh. One smoker said the sticker is "sneaky". Some smokers said they will continue using the sticker to hide the images. Quitline says since the graphic images first appeared in 2008, numbers of calls to its helpline have increased. But there are websites and even how-to videos dedicated to showing smokers how to cover the pictures up. This news story was resourced by the Oral Cancer Foundation, [...]

Ethics Being Questioned In Dentistry

Source: Scandals, lawsuits, a growing focus on commercialization and self-promotion, and dentists who prescribe excessive treatments are tarnishing the profession's image, according to a presentation on ethics at the recent ADA annual session in Las Vegas. Most dentists may be surprised that a Google search on ethical scandals among health professions shows that dentistry now gets more hits than medicine, nursing, chiropractics, and pharmacology, according to Ann Boyle, DMD, interim provost and vice chancellor for academic affairs at Southern Illinois University. Some of the public's changing perceptions toward dentistry can undoubtedly be traced to ubiquitous media coverage of scandals and malpractice lawsuits involving medical professionals, Dr. Boyle noted. Gordon Christensen, DDS, MSD, PhD, discussed the decline of dentists' credibility in a 2001 article, noting a Gallup poll showed that their ranking among professions had fallen below nurses, physicians, and veterinarians (Journal of the American Dental Association, August 2001, Vol. 132:8, pp. 1163-1165). Dentists were ranked third among the most trusted professionals in 1995 but slipped to ninth in 2001, according to Gallup poll rankings; they ranked sixth in 2009. Negative influences, according to Dr. Christensen, included commercialization and self-promotion, excessive treatment and fees, providing service only when it's convenient, and refusing to accept responsibility when treatment fails prematurely. “These front-line physicians consider us uncaring, selfish, greedy, and unprofessional.” — Ann Boyle, DMD, Southern Illinois University Dr. Boyle pointed to a 1997 Reader's Digest article about dentists' honesty. In it, the author visited 50 dentists in 28 states to see how [...]

Possible Link Between HPV and Heart Disease

Source: We already know HPV, or human papillomavirus, can cause cervical cancer. It's also known to cause some kinds of oral cancer. But could HPV also cause heart disease? An intriguing new study is drawing a link. The study found that women who are known to be infected with cancer-causing strains of the virus may be at increased risk for cardiovascular disease and stroke -- even when they have none of the usual heart disease risk factors. The study authors say their research is one of the first to investigate a potential link between heart disease and HPV, which is one of the most common sexually transmitted infections. The Public Health Agency of Canada estimates that more than 70 per cent of sexually-active Canadian men and women will have a sexually transmitted HPV infection at some point in their lives. They say they began the study because they wanted to know why some people have heart attacks even though they have none of the usual risk factors, like high cholesterol or high blood pressure. About 20 per cent of patients with heart disease lack risk factors, which has left open the possibility that underlying "nontraditional" causes might be involved in the disease. If there is indeed a link between the virus and heart disease, it could have a number of implications. It would mean that doctors would have to monitor patients with HPV to help prevent heart attack and stroke. As well, there is the possibility that the HPV vaccine [...]

HPV Vaccine Recommended for Boys aged 11 to 12 Years

Source: The CDC's Advisory Committee on Immunization Practices today approved routine recommendation in favor of administering the quadrivalent HPV vaccine for boys aged 11 to 12 years. Committee members decided that the vaccine (Gardasil, Merck) was safe, efficacious and cost-effective enough to warrant routine usage in this population. The recommendation issued in 2009 was permissive, meaning providers could give the vaccine to boys, but it was not routinely administered. This change would put the HPV vaccine into the regular vaccination schedule. The three-vaccination series can start as early as age 9 years. "The committee recommended that routine vaccination of males aged 11 or 12 years with three doses of quadrivalent vaccine be given to prevent HPV infection and HPV-related disease," Anne Schuchat, MD, director of the CDC's National Center for Immunization and Respiratory Diseases, said in a phone call with reporters. "Boys and young men 13 to 21 years of age who have not already received the vaccine should be vaccinated." Anne Schuchat, MD Insurance companies typically cover HPV vaccine in boys, but that is not necessarily the case for a permissive recommendation, according to Schuchat, who said a routine recommendation for a vaccine usually translates into coverage without co-pays. The committee voted 8-5 with one abstention in favor of recommending vaccination for young men up to age 21 years with permissive recommendation for men aged 22 to 26 years. The committee considered recommending vaccination up to age 26 years, which would have harmonized recommendations for men and women, [...]

CDC Committee Recommends Boys Receive HPV Vaccine

Source: A federal government advisory committee voted Tuesday to recommend that boys and young men, from ages 11 to 21, be vaccinated against the human papilloma virus, commonly referred to as HPV. The Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices says the vaccine series can be started as early as age 9. Twelve members of the committee voted in favor of a recommendation that 11- and 12-year-old boys be vaccinated; one member abstained. A separate vote involving males age 13 to 21 was split. Eight voted for it; five voted against, and one abstained. The same recommendation said males age 22 through 26 may be vaccinated. HPV is the No. 1 sexually transmitted disease in the United States. At least 50% of sexually active people will get it at some point in their lives. Study: Males should get HPV vaccine too The HPV votes took place as part of the advisory committee's meeting in Atlanta, Georgia. The HPV vaccine is already recommended for females between the ages of 9 and 26 to reduce the risk of cervical cancer. The CDC recommends girls get the vaccine at age 11 or 12. The FDA approved the first HPV vaccine, Gardasil, back in 2006. The second vaccine, Cervarix, was approved in 2009. The vaccine is given in three doses. Gardasil also protects against most genital warts and has been shown to protect against anal, vaginal and vulvar cancers, all of which are associated with HPV, according to the [...]

New Fire Pepper Jelly Proceeds Help Benefit The Bruce Paltrow Oral Cancer Fund

Source: Jenkins Jellies was recently started by actress Hillary Danner, who was encouraged by a friend to invent a unique pepper jelly that has an extra kick of flavor. She brought in friends Maria Newman and Chef Jared Lavy to help out, resulting in the creation of the delicious, one-of-a-kind Hell Fire Pepper Jelly. The jelly is headlined by a perfect balance between a sweet taste of jelly and the hot kick you would expect from peppers. Hell Fire Pepper Jelly is unique in that it is versatile, with an infinite number of uses. Couple it with a variety of cheeses to give your sandwiches an extra kick. Use it as a glaze or marinade on streak, salmon, pork or chicken. It also makes for a great topper on burgers, hot dogs and meatloaf. The product is completely organic, with nothing artificial about it, which means you get the pure, unaltered natural blend of flavors. There are no preservatives, artificial flavors, high fructose corn syrup or food coloring. The ingredients strictly include a blend of seven fresh peppers, vinegar, organic sugar and pectin. Plus, the jelly is completely vegan friendly and gluten free. This delicious product has rightfully been recognized by celebrities like Chef Mario Batali and actors Ed Begley, Jr. and Gwyneth Paltrow. It is a delicious topper that will make the boring burger or steak pop with a unique flavor. It is available at Dean & DeLuca stores across the country, as well as online. Part of the profits go to Green [...]

Proper dental care for cancer patients: why it is important

Source: Author: Alan B. Sheiner DDS Common side effects from radiation therapy are not stressed enough in dental schools, but they can be managed and even prevented. A few weeks ago, I was contacted by a retired physician with whom I had not spoken for a number of years since he retired from practice to become a “gentleman farmer” in the country. While I was happy to hear from him, his news was not so good. He was calling because he had been treated for base of tongue cancer and his teeth were “coming apart”. His cancer treatment consisted of chemotherapy and radiation therapy. Unfortunately, he somehow “slipped through the cracks” and his oral cavity was now suffering from some of the side effects of the cancer therapy – fortunately he is currently cancer free. The oral cavity, one of the most complex and visible organ systems in the body, is invariably compromised as a result of treatment for head and neck cancer. Whether the malignancy is to be treated by surgery, radiation therapy, chemotherapy or a combination of these modalities, the function, if not also the form, of the oral cavity will be impacted. Aside from the obvious physical changes after cancer surgery to the head and neck region, there are issues which usually accompany radiation therapy to the head and neck region. There may be side effects from cancer therapy, some of which can be devastating, but preventable or manageable with proper precautions and care. The most [...]

The versatile application of cervicofacial and cervicothoracic rotation flaps in head and neck surgery

Source: Author: staff The large defects resulting from head and neck tumour surgeries present a reconstructive challenge to surgeons. Although numerous methods can be used, they all have their own limitations. In this paper, we present our experience with cervicofacial and cervicothoracic rotation flaps to help expand the awareness and application of this useful system of flaps. Methods: Twenty-one consecutive patients who underwent repair of a variety of defects of the head and neck with cervicofacial or cervicothoracic flaps in our hospital from 2006 to 2009 were retrospectively analysed. Statistics pertaining to the patients'clinical factors were gathered. Results: Cheek neoplasms are the most common indication for cervicofacial and cervicothoracic rotation flaps, followed by parotid tumours. Among the 12 patients with medical comorbidities, the most common was hypertension. Defects ranging from 1.5 cm x 1.5 cm to 7 cm x 6 cm were reconstructed by cervicofacial flap, and defects from 3 cm x 2 cm to 16 cm x 7 cm were reconstructed by cervicothoracic flap. The two flaps also exhibited versatility in these reconstructions. When combined with the pectoralis major myocutaneous flap, the cervicothoracic flap could repair through-and-through cheek defects, and in combination with a temporalis myofacial flap, the cervicofacial flap was able to cover orbital defects. Additionally, 95% patients were satisfied with their resulting contour results. Conclusions: Cervicofacial and cervicothoracic flaps provide a technically simple, reliable, safe, efficient and cosmetic means to reconstruct defects of the head and neck. Authors: Fa-yu Liu, Zhong-fei Xu, Peng Li, Chang-fu Sun, [...]

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