Influences and predictors of long-term quality of life in head and neck cancer survivors
Source: Arch Otolaryngol Head Neck Surg. 2009;135(4):380-384. Authors: Mark W. El-Deiry, MD et al. Objective: To examine the impact of clinical predictors (pretreatment variables) and other influences (treatment and posttreatment variables) on long-term quality of life (QOL) in patients treated for squamous cell carcinoma of the upper aerodigestive tract. We hypothesized that baseline QOL and comorbidity would be predictors of QOL 1 year after treatment. Design: Retrospective cohort study. Setting: Academic Medical Center in Seattle, Washington. Patients: Patients (N = 173) with baseline (pretreatment) and 1-year posttreatment QOL data. Main Outcome Measure: Head and neck–specific QOL scores at 1 year after treatment (as measured by the University of Washington Quality of Life [UW-QOL] scale). Results: We identified strong relationships between 1-year UW-QOL scores and baseline UW-QOL scores (correlation coefficient [Pearson r] = 0.58; P