Bioscientists help throat cancer patients speak again

Source: medicalxpress.com Author: staff, provided by the University of Kent Voice Prosthesis Biofilm. Credit: Dr Campbell W. Gourlay, University of Kent Through the work of the School of Biosciences team, in collaboration with East Kent Hospitals University NHS Foundation Trust, Kent has developed a new method of care for patients who have to have their larynx removed. The Biosciences team found that the replacement voice boxes would last much longer if they dealt with the fungal infection Candida albicans that was causing the silicone versions to fail. For the first time, scientists were able to extend the life of the replacement voicebox by dealing with the fungal infection. The team has developed clinical care for patients that has now been taken up by many NHS Trusts in the UK and which is anticipated could be used worldwide for throat cancer patients. It means patients may be able to carry on using silicone voice prosthesis for much longer, enabling them to still speak and reducing the risk of dangerous secondary chest infections. Dr Campbell Gourlay, Senior Lecturer in Cell Biology at Kent, said the University's work, funded by the NHS and Kent Cancer Trust, will enable people who lose their larynx to maintain speech and enjoy a better quality of life.

2016-12-01T14:49:14-07:00December, 2016|Oral Cancer News|

“They don’t care:” Hamilton senior left five months without a voice

Source: www.thespec.com Author: Joanna Frketich Donna Thombs has not uttered a word in five long months. The east Hamilton senior is desperate to get her voice back, but has so far faced a waiting list with no room for compassion at St. Joseph's hospital. "It's terrible," mouths Thombs. "They don't care." The only sound is wheezing as she attempts to talk with gestures along with slowly mouthing out words using exaggerated movements. It takes multiple attempts to get across even the simplest words. Often, she shakes her head and just gives up. Credit: Hamilton Spectator Donna Thombs has been living in silence for five months as she awaits an operation to restore her voice following surgery for throat cancer. "Try not talking for one day," she mouths. "I've done it for months. Now, it's really starting to get to me." Thombs says the surgical procedure essential to giving her a voice takes roughly 20 minutes. She came achingly close when it was scheduled for Aug. 26, only to have it cancelled. As of Friday, Thombs had been given no information by the office of head and neck surgeon Dr. Michael Gupta on how much longer she'd have to wait. She'd been told her case was a low priority despite the safety concerns of a woman in her 80s living alone with no voice to call for help. Her relatives phone to check on her but her only way to communicate with them is to knock once to let [...]

2015-09-23T07:40:20-07:00September, 2015|Oral Cancer News|

Improving QOL in head and neck cancer as survival improves

Source: www.medscape.com Author: Zosia Chustecka In patients undergoing radiation treatment for head and neck cancer, reducing the radiation to organs not affected by cancer is key to improving quality of life post-treatment. Several studies presented here at the 2014 Multidisciplinary Head and Neck Cancer Symposium described new approaches to sparing radiation delivered to the salivary glands and to the voice box, without any loss of cancer control, but with a reported reduction in adverse effects, such as xerostomia (dry mouth), and an anticipated reduction in loss of voice and speech quality. Improvements in such outcomes are becoming increasingly important as the epidemiology of head and neck cancer is changing, and the increase in human papillomavirus-positive disease means that patients are being diagnosed their 50s and will, in many cases, go on to live for decades after their definitive cancer treatment, researchers commented at a press briefing. Xerostomia can make it difficult to speak, as well as chew and swallow, and can lead to dental problems. "Dry mouth might seem trivial, but it actually has a significant effect on quality of life," commented Tyler Robin, PhD, an MD candidate in his final year at the University of Colorado Medical School in Denver. To reduce this adverse effect, intensity-modulated radiation techniques are already directing the beam away from the parotid gland, which is responsible for stimulated saliva production, for example during eating. But for the rest of the time, saliva is produced unstimulated from the submandibular gland. "This gland actually produces the [...]

2014-02-28T14:23:04-07:00February, 2014|Oral Cancer News|

Michael Douglas: ‘Throat cancer’ was really tongue cancer

Source: cnn.com Author: Jen Christensen, CNN Michael Douglas never had throat cancer, as he told the press in 2010. The actor now says he had tongue cancer. Douglas said he hid the diagnosis at the urging of his doctor to protect his career. "The surgeon said, 'Let's just say it's throat cancer,' " Douglas told fellow actor Samuel L. Jackson for a segment that ran on British television as a part of Male Cancer Awareness Week. Douglas says that the doctor told him if they had to do surgery for tongue cancer, "it's not going to be pretty. You could lose part of your tongue and jaw." When Douglas first talked about his cancer diagnosis in the summer of 2010, he was on a worldwide publicity tour for the movie "Wall Street: Money Never Sleeps." Douglas and Jackson joked that could have been the end of his acting career. Douglas said if he had surgery he could see the director saying, "What's your good side? I've got no side over here." "There really is no such thing as throat cancer per se," explained Brian Hill, an oral cancer survivor and the founder of the Oral Cancer Foundation. Douglas has taped a public service announcement to raise awareness about oral cancer for Hill's foundation. "Throat" cancer and tongue cancer are both colloquial terms that fall under the oral cancer umbrella. Throat cancer usually refers to cancerous tumors that develop in your pharynx, voice box or tonsils. Tongue cancer refers to cancerous [...]

Novel one-step system for restoring voice in throat cancer patients

Source: medicalxpress.com This picture shows the cannula (A) and the tool (B) for inserting the voice prosthesis which is usually made of silicon (partly shown on the left side of the tool). This tool will then be inserted into the cannula so that it can be injected into the patient's fistula according to the length required, using the calibration on the cannula. Credit: National University of Singapore. Patients who have lost their voice box through disease such as throat cancer may be able to speak immediately after a procedure to create a small opening at the throat. A novel system developed through an Engineering-in-Medicine project led by Dr Chui Chee Kiong, NUS Department of Mechanical Engineering, and Dr David Lau, Consultant Ear, Nose & Throat (ENT) Surgeon at Raffles Hospital, cuts down a two-week duration before patients can speak, to about 10 minutes after the initial procedure. People who undergo laryngectomy and lose their voice box can recover approximately 80 per cent of normal speech by having a voice prosthesis fitted into an opening or fistula between the trachea (windpipe) and esophagus (food pipe). To speak, the patient covers the stoma (breathing opening in the neck) with his or her thumb and forces air through the prosthesis into the esophagus and out through the mouth. Before the prosthesis can be inserted, the doctor needs to make a small puncture (tracheo-esophageal puncture or TEP) in the wall between the trachea and esophagus. During the puncture, a guide-wire is inserted into the [...]

Blacks with throat cancer get harsher therapy

Source: in.reuters.com Author: Frederik Joelving Blacks in the United States with throat cancer are more likely than whites to have surgery that leaves them unable to speak than to get gentler voice-preserving therapy, according to a study. Previous research has found a similar racial disparity in breast cancer treatment, with blacks more often having the entire breast removed instead of just the cancerous lumps. It's unclear why the disparity exists. But study leader Allen Chen, a radiation oncologist at University of California, Davis, said that poverty, less education and deep-rooted historical biases could all be at work. "There could be an underlying distrust among African Americans where they feel anything less than surgery might be considered quote-unquote experimental," Chen told Reuters Health. He referenced the Tuskegee experiment, conducted by the U.S. government from the 1930s into the 1970s, in which black patients with syphilis went untreated despite assurances to the contrary. "That sort of distrust needs to be addressed or alleviated," Chen said, because voice-preserving treatment for throat cancer, based on radiation and drug therapy, is now the standard. His study, published in the Archives of Otolaryngology - Head & Neck Surgery, is based on data from a US cancer registry including nearly 5,400 cases of laryngeal cancer between 1991 and 2008. About 80 percent of whites had voice-preserving treatment, while the rest had their voice box surgically removed - the traditional approach. Among blacks, 75 percent had the gentler therapy. While that's only a five-percent difference, "I think that's [...]

New surgical approach can remove throat tumor and rebuild trachea

Source: www.news-medical.net Author: staff Using a novel surgical approach, it's possible to rebuild the trachea and preserve a patient's voice after removing an invasive throat tumor, according to a new report from Henry Ford Hospital in Detroit. This case study is the first of its kind to not only document a successful technique to create a fully functional trachea, or windpipe, but also report a rare type of malignant tumor in an adult's trachea. Most commonly, this type of tumor is seen in newborns and very rarely occurs in the neck, says lead study author Samer Al-Khudari, M.D., with the Department of Otolaryngology-Head & Neck Surgery at Henry Ford Hospital. "In this case, the patient's tumor had spread to the trachea, thyroid gland, muscles around the thyroid gland and nerves in the area," says Dr. Al-Khudari. According to head and neck cancer surgeon Tamer A. Ghanem, M.D., Ph.D., who led the Henry Ford surgical team, the easiest approach would have been to remove the trachea and the voice box, given the tumor's proximity to the larynx and other surrounding structures. With this method, however, the patient would no longer be able to speak or swallow normally. Instead, the surgical team took another approach. Using tissue and bone from the patient's arm, they were able to reconstruct the trachea, restoring airflow through the trachea and saving the patient's voice. "We had to think outside the box to not only safely remove the tumor, but to allow for optimum functional outcome," says [...]

Determined to play: man uses air compressor to play saxophone

Source: www.theindependent.com Author: Tracy Overstreet Jerry True just has the music in him. "Anything I touch -- it plays for me," he said. So when throat cancer took away his voice box -- and the air he needed to play the saxophone -- he took up the drums. But that was only until he could manufacture a way to play his Selmer mark VI B-flat sax with an air compressor. "It took me two years to get it just right," True said. True is now back on the band circuit playing in the front row for the Paul Kothe band of Hastings. "We've been playing together for 35 years," True said of Kothe. "He sounds just like he always did," Paul Kothe said. "He has a beautiful sound." True was front and center at the Feb. 21 Kolache Shoot-Out in Elba playing his saxophone with the Kothe Band. The band paused long enough for judges to announce the kolache winners and then for the audience to sing "Happy Birthday" to True -- his 83rd. True was raised in Arcadia and taught himself how to play the sax when his father, a part-time string instructor, brought the instrument home and couldn't make it work. "He sounded like a Canadian goose," True said through the Servox voice simulator he touched to his throat. But the instrument Leonard True couldn't get to work, simply sang for his son. "I was in a dance band by the time I was 12," True said. True's [...]

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