Which cancers have increased over the past decade?

Source: www.mdlinx.com Author: Naveed Saleh, MD, MS, for MDLinx The incidence of cancers at the level of the oral cavity and pharynx increased between 2007 and 2016, according to a recent report by researchers from the CDC published in Morbidity and Mortality Weekly Report. This rise occurred despite respective decreases in the incidence of cancers at various anatomic sites. Cancers of the oral cavity and pharynx make up 3% of cancers diagnosed in the United States each year, with risk factors including tobacco use, HPV infection, and excessive alcohol intake. “The overall increase appears to be driven by increases in cancers of the tonsil, base of tongue, oropharynx, and other cancers of the oral cavity and pharynx, which are HPV-associated, as well as by those of gum and anterior tongue,” wrote the authors. Breaking down the numbers On average, the incidence rates for cancers of the oral cavity and pharynx combined increased by 0.6% per year between 2007 and 2016, with specific increases as follows: Oral cavity and pharynx (3.4%) Base of tongue (1.8%) Anterior tongue (1.8%) Gum (1.9%) Tonsil (2.4%) Oropharynx (1.9%) For the following cancers, however, incidence rates decreased: Soft palate and uvula (−3.7%) Hard palate (−0.9%) Floor of mouth (−3.1%) Lip (−2.7%) Hypopharynx (−2.4%) Nasopharynx (−1.3%) Of note, the incidence of cheek and other mouth and salivary gland cancers remained unchanged.

With HPV-related head and neck cancers rising, focus on treatment and vaccination

Source: blogs.wsj.com/health Author: Laura Landro A form of head and neck cancer associated with the sexually transmitted human papillomavirus is on the rise, especially in men, the WSJ reports. Fast-rising rates of oropharyngeal cancer — tumors in the tonsil and back-of-the-tongue area — have been linked to changes in sexual behavior that include the increased practice of oral sex and a greater number of sexual partners. But HPV-positive cancer has also been reported in individuals who report few or no sexual partners. It may also be possible for the virus to be transmitted to an infant via an infected mother’s birth canal. An HPV vaccine is routinely recommended for girls because the virus can cause cervical cancer. The rise in HPV-positive head and neck cancers is leading to a new focus both on treatment of the disease, and whether recommending routine vaccination for boys could prevent oral infections and cancers. (A CDC advisory panel said in 2009 that it was fine for boys to get the vaccine, but recommended against routine administration.) Eric Genden, chief of head and neck oncology at Mt. Sinai Medical Center, tells the Health Blog that when treated appropriately, patients with HPV-positive cancers have an 85% to 90% disease-free survival rate over five years. By contrast, patients with HPV-negative head and neck cancers, which are often associated with smoking and drinking, typically have more advanced disease when the cancer is detected and face a five-year survival rate of only 25% to 40%, Genden says. HPV-induced head [...]

Doctors study link between oral cancer and HPV – suggest males should also be vaccinated

Source: www.theprovince.com Author: Iris Winston, Canwest News Service Oral cancer brings to mind images of longtime chain smokers and grizzled tobacco chewers. But the risk factors for cancers of the mouth and throat now include sexual activity as well as all forms of tobacco use and alcohol consumption. "Over the 20 years I have been in practice, I have treated a few rodeo riders and baseball players who use chewing tobacco or snuff, as well as smokers," says Dr. Joseph Dort, a professor of head and neck surgery at the University of Calgary's faculty of medicine and president of the Canadian Society of Otolaryngology. "Classically, people think of oral cancer as something that occurs in smokers and drinkers and usually among people in their 50s, 60s or even older. But, over the last 10 years or so, we have become aware that the human papillomavirus (HPV) -- the same virus that is associated with cervical cancer -- has now been strongly associated with certain kinds of head and neck cancer, specifically the tonsil and tongue-based cancers, and that they are becoming more prevalent in people who are younger than the usual cohort." Dr. Linda Lee, a specialist in oral pathology and oral medicine who is the staff dentist at Toronto's Princess Margaret Hospital, has seen a similar trend. "Because people are smoking less, we would expect to see a decline in oral cancer," she says, "but it hasn't declined and this is probably because of the HPV factor. We have [...]

Strides made in tonsil cancer repair

Source: health.usnews.com Author: staff Surgery on tonsil cancer patients can spell trouble for the palate, but now researchers say they've developed a technique that helps preserve the ability to speak clearly and eat most foods. Traditionally, surgeons use big pieces of tissue to reconstruct the area after tonsil tumors are removed. But the patients who undergo this treatment can suffer "quality of life issues," study author Dr. Douglas Chepeha, an associate professor of otolaryngology, head and neck surgery and director of the microvascular program at the University of Michigan Health System, said in a school news release. The treatment "affects speech and eating -- typically, patients have difficulty eating when they have this kind of tumor and undergo surgery," he said. The new treatment, which uses tissue from another part of the body, helps ensure that the tongue can move more efficiently. The study authors, who report their findings in the current issue of the Archives of Otolaryngology Head & Neck Surgery, followed 25 patients with tonsil cancer for an average of five years. "In particular, patients who have less than half their palate removed do very well with this reconstruction. We're trying to make sure the remaining tongue and palate they have really work. Our goal is to get patients eating in public and back to work," Chepeha said. Tonsil cancer is a form of throat cancer, which will kill an estimated 2,230 Americans this year.

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