How regular use of painkillers could boost survival rates from cancer

Source: www.mirror.co.uk Author: Miriam Stoppard In recent research, aspirin or ibuprofen were found to treble the chance of beating head and neck cancer. Could regular use of aspirin or ibuprofen boost survival rates from head and neck cancer? It seems it’s possible. In recent research, the common painkillers were found to treble the chance of survival (from 25% to 78%) for patients with a specific kind of cancer which contains an altered gene, known as PIK3CA. Around a third of head and neck cancers carry this mutation and it’s also found in other types of cancer. Head and neck cancer is newly ­diagnosed in more than 12,000 people in the UK each year, and in 65,000 in the US. It kills just over 4,000 people here and 14,000 in America. There are more than 30 areas in the head and neck where cancer can develop, such as the mouth and throat. Researchers at the University of ­California, San Francisco, looked at five-year survival rates for people ­diagnosed with the disease and found the regular use of non-steroidal anti-inflammatory drugs (NSAIDs), such as aspirin and ibuprofen, significantly improved survival for a third or more of patients with the disease. All the patients had the mutated gene. NSAIDs, however, had no effect on tumours without PIK3CA mutation. The study included 266 patients from the University of Pittsburgh Medical Center whose tumours were surgically removed. Altogether, 75 tumours (28%) in the study had a change in the PIK3CA gene. Among the patients who [...]

NSAIDs may cut oral cancer risk

Source: www.newsfix.ca Author: Martin March People who smoke are protected from oral cancer by aspirin or ibuprofen, according to a study. It’s already known that smoking is a strong risk factor for oral cancer. A study from the Norwegian Radium Hospital reveals that non-steroidal anti-inflammatory drugs (NSAIDs) may help protect some smokers from the disease. They looked at a group of light to moderate smokers who had taken NSAIDs over a long period. They were about 65 per cent less likely to develop oral cancer compared to smokers who did not take NSAIDs. All types of NSAID were protective, including ibuprofen, aspirin and indomethacin. However, acetaminophen, a common pain reliever which is not an NSAID, was not found to be effective. The benefit of NSAIDs was found to be greatest for those who smoked least. At higher levels of consumption of tobacco, its carcinogenic effect overcomes the benefit of the NSAID.

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