heart attack – Oral Cancer News

Scientists say that E-Cigarettes and Snuff are not harmless

Author: Eliza GraySource: time.com New research casts doubt on nicotine's safety—even if you aren't smoking New research from the American Heart Association journal Circulation shows that patients who stopped using smokeless tobacco after a heart attack had improved life expectancy—similar to that of people who quit smoking. The finding offers new information about the dangers of smokeless tobacco, the risks of which are not as well understood as cigarettes’. “That was a big surprise for us,” said Dr. Gabriel Arefalk, lead researcher and a cardiologist at Uppsala University Hospital in Uppsala, Sweden. “For smoking, it has been known for decades now that people benefit from discontinuation, especially after having suffered a heart attack, but for snus we had no idea what to expect. ”The researchers reviewed data on 2,474 heart attack survivors under 75 in Sweden who used snus (oral snuff) from 2005 to 2009. About 675 quit. During the two years of follow-up, 69 of those who continued using snus died, compared with only 14 quitters. Based on this data, researchers determined that those who quit snus had almost half the mortality risk of those who didn’t quit, which is similar to the benefit of smoking cessation, according to a release from the American Heart Association. Dr. Arefalk, who is also a clinician, said the researchers wanted to study the problem because they didn’t know what to tell patients about the risks of using snus after a heart attack. He cautioned that the study was small and far from enough to [...]

Charlotte Parker2014-06-25T11:44:46-07:00June, 2014|Oral Cancer News|

Temple researchers show targeted cancer drug may stunt heart’s ability to repair itself

Source: EurekaAlert! Date: November 6, 2012 (Philadelphia, PA) – Scientists for the first time have evidence showing how a widely used type of "targeted" cancer drug can be dangerous to the heart. Studying mice with the equivalent of a heart attack, researchers found that the drug sorafenib (Nexavar) – which inhibits proteins called tyrosine kinase receptors (RTKs), and is used in kidney and liver cancer treatment – can interfere with heart stem cell activity, affecting the heart's ability to repair itself after injury. The findings suggest that sorafenib and other similar drugs that target these kinds of protein receptors may raise the risk for heart attack for some cancer patients with underlying heart disease, as well as affect the heart's ability to repair damage. By understanding how these cancer drugs can affect the heart, scientists and clinicians may be able to devise new treatment strategies to lessen such potentially damaging effects of often vital cancer drugs. "The goal is not to take the drug off of the market – it's a very good and useful drug that cancer patients need. We're trying to understand how this cancer drug and others like it can affect the heart, and what types of individuals might be at risk for problems," said senior author Steven Houser, PhD, Professor and Chair of Physiology at Temple University School of Medicine and Director of Temple's Cardiovascular Research Center. "Our results are beginning to provide a clearer picture of some of the potential physiological mechanisms at play." Dr. [...]

Charlotte Parker2012-11-09T11:25:06-07:00November, 2012|Oral Cancer News|

Aspirin Cuts Death Rate From Several Common Cancers

Source: Web MD Taking aspirin over a long period of time can substantially cut the risk of dying from a variety of cancers, according to a study showing that the benefit is independent of dose, gender, or smoking. It also found that the protective effect increases with age. The study is by Peter Rothwell, MD, PhD, FRCP, of John Radcliffe Hospital in Oxford, England, and colleagues, and has been published online by the journal the Lancet. A previous study by the same authors showed that low doses of aspirin (75-300 milligrams) reduced the number of cases of colorectal cancer by a quarter and deaths caused by the disease by more than a third. The latest study confirms the earlier results and concludes that similar effects can be shown for other types of cancers. The study looked at eight trials examining the effects of a daily dose of aspirin on preventing heart attacks involving 25,570 patients, 674 of whom died from cancer. They showed a 21% reduction in the number of deaths caused by cancer among those who had taken aspirin, compared with people who had not. The investigation also showed that the benefits of taking aspirin increased over time. After five years, death rates were shown to fall by 34% for all cancers and by 54% for gastrointestinal cancers. Participants were also followed up after 20 years, by which point 1,634 of the original participants had died as a direct result of cancer. This 20-year follow-up established that the risk [...]

Oral Cancer Foundation News Team - A2010-12-22T11:18:57-07:00December, 2010|Oral Cancer News|

Smokeless tobacco won’t help smokers quit

Source: www.webmd.com Author: Bill Hendrick Smokeless tobacco products -- whether chewed or used as dry or moist snuff -- may increase the risk of heart attack, fatal stroke and certain cancers, says a new policy statement published online in Circulation: Journal of the American Heart Association. "No tobacco product is safe to consume," Mariann Piano, PhD, lead writer of the policy statement and a professor in the department of behavioral health science at the University of Illinois at Chicago, says in a news release. The notion that smokeless tobacco may help reduce the rate of cigarette smoking is based in part on Swedish research, which showed a significant decline in smoking by Swedish men between 1976 and 2002 that corresponded with an increase in the use of smokeless tobacco. But in similar research in the U.S., the opposite was found to be true, the article says. There was no reduction in smoking rates among people who used smokeless tobacco products. Nicotine-Replacement Therapy Piano says that smokers trying to kick the habit might want to try nicotine-replacement therapy, by chewing nicotine gum or using a nicotine patch that can be attached to the skin, rather than using smokeless tobacco products. Piano tells WebMD that most people who use nicotine-replacement therapy do so for short periods of time, and it doesn't appear to be as addictive as smokeless tobacco "because of slower absorption, lower doses of nicotine, greater cost, lack of flavoring, sociocultural influences" or a combination of such factors. She says [...]

Oral Cancer Foundation News Team - A2010-09-14T09:06:26-07:00September, 2010|Oral Cancer News|

Smoking ban heart gains ‘massive’

Source: news.bbc.co.uk Author: staff Bans on smoking in public places have had a bigger impact on preventing heart attacks than ever expected, data shows. Smoking bans cut the number of heart attacks in Europe and North America by up to a third, two studies report. This "heart gain" is far greater than both originally anticipated and the 10% figure recently quoted by England's Department of Health. The studies appear in two leading journals - Circulation and the Journal of the American College of Cardiology. Heart attacks in the UK alone affect an estimated 275,000 people and kill 146,000 each year. Big impact Earlier this month it was announced that heart attack rates fell by about 10% in England in the year after the ban on smoking in public places was introduced in July 2007 - which is more than originally anticipated. But the latest work, based on the results of numerous different studies collectively involving millions of people, indicated that smoking bans have reduced heart attack rates by as much as 26% per year. Second-hand smoke is thought to increase the chances of a heart attack by making the blood more prone to clotting, reducing levels of beneficial "good" cholesterol, and raising the risk of dangerous heart rhythms. Dr James Lightwood, of the University of California at San Francisco, led the Circulation study that pooled together 13 separate analyses. His team found that heart attack rates across Europe and North America started to drop immediately following implementation of anti-smoking laws, [...]

Oral Cancer Foundation News Team - A2009-09-22T05:10:54-07:00September, 2009|Oral Cancer News|

Up in smoke: health insurers hold billions in tobacco stocks

Source: Southernstudies.org Author: Desiree Evans A recent study published in the New England Journal of Medicine found that major U.S., Canadian and British life and health insurance companies are investing billions of dollars in tobacco company stock. Researchers first revealed that health and life insurance companies had major investments in tobacco companies in 1995 in an article in the British medical journal Lancet. More than 10 years later, insurance companies are still deeply invested in "big" tobacco, despite the national calls upon them to divest. "Despite calls upon the insurance industry to get out of the tobacco business by physicians and others, insurers continue to put their profits above people's health," said Wesley Boyd, the new report's lead author and a faculty member of Harvard Medical School. "It's clear their top priority is making money, not safe-guarding people's well-being." The report found that seven health and life-insurance companies in both the United States and overseas have nearly $4.5 billion invested in companies whose affiliates produce cigarettes, cigars and chewing tobacco. "Although investing in tobacco while selling life or health insurance may seem self-defeating, insurance firms have figured out ways to profit from both," Boyd said. "Insurers exclude smokers from coverage or, more commonly, charge them higher premiums. Insurers profit -- and smokers lose -- twice over." The study highlights New Jersey-based Prudential Financial Inc., which sells life insurance and long-term disability coverage. With total tobacco holdings of $264.3 million, Prudential Financial is a major investor in three tobacco firms, including America's biggest cigarette [...]

Charlotte Parker2009-06-19T07:41:28-07:00June, 2009|Oral Cancer News|