Hepatitis C Virus strongly linked to head and neck cancer: study

Source: www.techtimes.com Author: Deepthi B, Tech Times People infected with the Hepatitis C virus (HCV), one of the most common blood-borne virus infections, are more prone to developing particular types of head and neck cancer, according to a new study. Researchers from the Univerity of Texas MD Anderson Cancer Center have revealed that HCV-infected people are at a higher risk of developing these cancers by around two to five times more than those without the Hepatitis C infection. "What we are trying to make all understand is that this is an infection that has consequences – and it's an infection we can cure," said Dr. Harrys Torres, lead author and an associate professor of infectious diseases at the university. Torres further explained that the Hepatitis C infection is easily curable and that over 90 percent of the HCV-related cases can be cured without any trouble simply by taking antiviral drugs, although they are expensive. Also, it is recommended that people should ensure timely screenings and appropriate treatment for HCV, as this can considerably prevent the condition from developing in the body. Hepatitis C appallingly affects more than 3.5 million Americans, according to the U.S. Centers for Disease Control and Prevention. Sadly, several of them are not even aware that they are infected with the virus. For the purpose of the study, researchers examined medical records from over 34,500 patients tested for HCV at the cancer center from 2004 to 2014. The researchers discovered that patients suffering from hepatitis C seemed [...]

High incidence of multiple primary carcinomas in HCV-infected patients with oral squamous cell carcinoma

Source: Med Sci Monit, September 1, 2009; 15(9) Authors: Y Nagao and M Sata Background: Hepatitis C virus (HCV) infection has been associated with several extrahepatic manifestations. Oral cancer is one of them. We investigated the association among oral squamous cell carcinoma (OSCC), multiple primary cancers (MPCs), insulin resistance and HCV infection. Material/Methods: Upper gastrointestinal tract examination and determination of the presence of HCV infection were routinely done for 60 primary OSCC patients. Occurrence of MPCs was evaluated between 1992 and 2008. Results: Of the 60 patients, 21 (35%: 15 males and 6 females; mean age 67.3+/-11.9 years) developed MPCs. Antibodies to HCV were found in 26.7% (16/60) of cases. The incidence of MPCs in HCV-infected OSCC cases was 62.5% (10/16 cases, P<0.01 vs the non-HCV-infected OSCC group); for cases without HCV infection it was 25% (11/44 cases). In HCV-infected cases, 10 MPCs with patients, hepatocellular carcinoma (HCC) was the most common outcome (5 cases), whereas gastric cancer was the most common outcome (6 cases) in non-HCV-infected 11 MPCs. In logistic regression analysis, the adjusted odds ratios on staging IV, anti-HCV positive, and over 70 years old were 15.50, 13.45, and 4.46, respectively, indicating that there were significant differences. Furthermore, the patients with HCV-infected MPCs had hyperinsulinemia. Conclusions: HCV infection was strongly associated with the occurrence of MPCs as well as primary OSCC. HCV-infected OSCC patients in Japan should receive medical treatment to inhibit development of HCC. In patients with HCV infection, it is important to clinically examine organs other [...]

2009-09-08T17:24:19-07:00September, 2009|Oral Cancer News|
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