Another setback for vapes? Using the devices can increase the risk of oral cancer as much as cigarettes do, study finds

Source: www.dailymail.co.uk Author: Cassidy Morrison, Senior Health Reporter DailyMail.com Using a vape causes cancer-linked DNA damage to the mouth at the same rate as using a cigarette does, study finds. The latest study from researchers at the University of Southern California (USC) further pokes holes in the notion that vaping e-cigarettes such as Juul and PuffBar devices are a healthier alternative to smoking. Vapers who regularly use e-cigarettes saw just as much damage to DNA in their mouths as smokers of regular tobacco cigarettes, raising the specter of chronic diseases including cancer. Flavor pods in particular were the most dangerous. Cancers are caused by such DNA damage, also referred to as gene mutations that, over time, may stop working normally or grow out of control and become cancerous. This is not the first study to come to this conclusion. Canadian researchers found that mice exposed to flavored vapes consistently suffered serious cellular and molecular damage to their lungs. Dr Ahmad Besaratinia, senior author of the study and public health experts at USC, said: ‘For the first time, we showed that the more vapers used e-cigarettes, and the longer they used them, the more DNA damage occurred in their oral cells.’ Smoking exposes the cells coating the inside of the mouth, the airways, and the lungs to dozens of powerful chemical carcinogens. The cells in parts of the body that are directly exposed to smoke are damaged most acutely, with 150 mutations found to occur in each lung cell within one [...]

2023-02-18T14:11:07-07:00February, 2023|Oral Cancer News|

Shades of Big Tobacco: How (and why) Juul bought an entire issue of a scientific journal

Source: Salon Date: July 20th, 2021 Author: Jon Skolnik   Facing the imminent threat of corporate death, the embattled e-cigarette maker Juul is pulling out all the stops in its fight to convince the Food and Drug Administration that its vaping products are more beneficial than harmful. If that sounds like a stretch, it probably is. Last month, Juul settled a $40 million lawsuit that accused the company of luring in teens to use its flavored vape products, allowing Juul to avoid the potential PR nightmare of a widely covered jury trial. Juul has also spent tens of millions in federal lobbying efforts over the past several years, presumably in an effort to block comprehensive regulations on the sale of e-cigarettes. But the most bizarre Juul news came two weeks ago, when the New York Times reported that the company had funded an entire issue of a scientific journal, in which every article presented evidence that vaping is a beneficial harm-reduction practice that can wean smokers off tobacco cigarettes. Last month, the American Journal of Health and Behavior (AJHB), a 44-year-old academic journal that has published many nationally recognized scholars, released a special edition specifically devoted to the question of whether e-cigarettes are harmful or helpful. The 219-page issue is unusual not just by virtue of its niche subject matter — e-cigarettes are a relatively new phenomenon in the field of health behavior — but also because its publication was bankrolled entirely by one source: Juul Labs. This fraught episode comes at an exceptionally tumultuous time for the vape maker. In early 2019, Juul, a company founded just four [...]

2021-07-20T13:15:56-07:00July, 2021|Oral Cancer News|

Need another reason not to vape? Your oral health is at risk

Source: www.health24.com Author: Healthday staff The warnings about vaping – inhaling the vapour of electronic cigarettes – tend to focus on the potential dangers to the heart and lungs. But an increasing amount of research shows the chemicals in e-cigarettes start to inflict damage right where they enter the body: your mouth. Because e-cigarettes are a recent phenomenon, said Dr Crystal Stinson, assistant professor at Texas A&M College of Dentistry in Dallas, "Studies on their impact are really new. But now we have a solid amount of evidence that shows the link between e-cigarettes and poor oral health." Nicotine, whether smoked or vaped, restricts blood flow to the gums, which can contribute to periodontal disease. The fluid in e-cigarettes, which can include propylene glycol, benzene, formaldehyde and other chemicals, only increases the risks. Irreversible issues A study published earlier this year in the journal iScience showed that 43% of people using e-cigarettes had gum disease and oral infections. That figure was higher among smokers – 73% – but only 28% among people who neither smoked nor vaped. "The oral cavity is really resilient tissue that heals faster than other parts of the body," Stinson said. "But we also know that when you repeatedly traumatise it, that's when you end up having issues that are irreversible." Those issues, she added, range from inflammation and tooth cavities to loss of bone that anchors teeth to the jaw, called periodontitis, and oral cancer. Another study published in May in Science Advances concluded the [...]

2020-09-08T06:09:52-07:00September, 2020|Oral Cancer News|

E-cigarettes found to cause change in mouth bacteria – which could lead to gum disease or oral cancer

Source: theconversation.com Author: Beth Daley E-cigarettes are a popular alternative to smoking, but we still know very little about the effects of them on our health. While numerous studies have explored the effect of e-cigarettes on our lungs, heart, and overall health, one important and often overlooked consideration is what effect they have on our microbiome. But a recent study has found e-cigarettes change the bacteria in our mouths. These bacterial changes can lead to disease, if left unchecked. Our microbiome is the living community of bacteria, fungi, and viruses that keep us healthy. We often hear a lot about our gut microbiome, but our oral microbiome is probably just as important to our overall health. It’s the second and most diverse microbiota next to the gut, home to over 1,000 species of microbes. It’s the gateway to the rest of our digestive system and plays a key role in helping us break down foods. Our oral microbiome also wards off potentially harmful microbes by preventing them from reproducing. A healthy oral microbiome reduces the chances of developing infections or disease. A recent study in Science Advances(1) investigating the effect of e-cigarettes on our oral microbiome found that e-cigarettes have a negative impact on the diversity of the bacteria present. They also cause an immune response from cells, which can lead to long-term damage to the surrounding cells. Our oral microbes are not only the first to experience e-cigarette vapour, they’re also exposed to higher concentrations of the chemicals. This [...]

The US surgeon general just issued a rare advisory about e-cigs like the Juul — here’s why vaping is so dangerous

In a rare national advisory, the top US public health official warned Americans of the dangers of e-cigarettes like the Juul, a popular device that lets users inhale nicotine vapor without burning tobacco. US Surgeon General Jerome Adams said in the advisory on Tuesday that e-cigs like the Juul are a particular danger to kids and teens and called for fresh measures to halt their rising popularity. "We need to protect our kids from all tobacco products, including all shapes and sizes of e-cigarettes," Adams said in a statement, adding, "We must take action now to protect the health of our nation's young people." The advisory singles out Juul multiple times, saying the sleek devices are popular among teens because they're easy to conceal and don't emit much odor. It tells parents, health professionals, and teachers to be on the lookout for all forms of nicotine-delivery devices, including e-cigs. Adams' announcement comes on the heels of warnings from several other federal agencies about a rise in e-cig use, including from the Centers for Disease Control and Prevention and the Food and Drug Administration. In November, after new CDC data pointed to a 78% increase in e-cig use among high-school students, FDA Commissioner Scott Gottliebannounced moves to further restrict sales of e-cigarettes to prevent them from getting into the hands of young people. That included a crackdown on flavored offerings, which researchers say appeal strongly to young people. Several days before the FDA's announcement, Juul Labs, the Silicon Valley startup behind the most popular e-cig in the US, temporarily halted sales of [...]

2018-12-19T16:41:28-07:00December, 2018|Oral Cancer News|

Tobacco 21 — its time has come

Source: vtdigger.org Author: Nevin Zablotsky, DMD As we approach the holiday season I am reminded of the gifts of love we share with our families, as well as the New Year’s resolutions we make and try to keep after Jan. 1 history. I am a periodontist having practiced in Burlington and South Burlington for the past 40 years. In that time I have treated patients that have been severely compromised by tobacco. Some have lost teeth from advanced periodontal disease and some have lost parts of their tongue and jaw due to oral cancer, leaving them significantly compromised functionally as well as well as emotionally. I have had to advise teenagers and their families that their tobacco chewing habit had caused significant enough changes in their mouth to warrant a biopsy of the involved area. This caused great stress to them as they waited a week to find out the results. Some may think that it takes many years for tobacco use to compromise one’s health, but teenagers can die a horrible death from tobacco use if they are one of the unlucky ones who is genetically predisposed to oral cancer. Over the years, I have traveled throughout Vermont teaching about tobacco and nicotine addiction to elementary, junior and senior high school students. I feel that I have a good sense of what kids are thinking about these subjects. The elementary school students seem to understand that cigarettes are bad for them. When one talks to the middle school kids, [...]

2018-12-11T20:44:16-07:00December, 2018|Oral Cancer News|

Forms of tobacco that give you cancer

Source: www.medicalnewstoday.com Author: Zawn Villines, reviewed by Philip Gregory, PharmD, MS Nicotine is the primary substance in cigarettes that causes addiction, but most experts agree that it does not directly cause cancer. Most research points to cigarette smoke, not nicotine, as being the primary contributor to cancer among smokers. However, although most experts agree that nicotine does not directly cause cancer, some research suggests that nicotine may lead to a type of DNA damage that increases the risk of cancer. Research from 2015 reported in the Indian Journal of Medical and Paediatric Oncology suggests that nicotine may increase the risk of cancer because it might damage DNA, initiate cancer and cause it to progress faster, and interact with cancer-causing chemicals. Research into the role of nicotine in cancer is ongoing. Many studies, however, do not differentiate between nicotine, tobacco, or smoking when they discuss cancer risk. This makes it difficult to determine which of them causes cancer. Even if nicotine does cause or lead to cancer, the risks of developing cancer through the use of nicotine-only products are much lower than the risks from smoking. Methods of consuming nicotine and their safety Nicotine is addictive and is the primary reason most people smoke. However, almost every other nicotine-based product is safer than smoking. No nicotine replacement product is completely safe for all people, but some of the less harmful alternatives include: Nicotine replacement therapy A person with a heart condition should speak to a doctor before undergoing NRT. Nicotine replacement [...]

2018-11-01T07:55:23-07:00November, 2018|Oral Cancer News|

AN E-CIGARETTE COMPANY PUT VIAGRA AND CIALIS IN ITS VAPING LIQUIDS, AND THE FDA IS NOT PLEASED

Source: newsweek.com Date: 10/13/18 Author: Kelly Wynne A vape company, HelloCig Electronic Technology Co., has included Viagra and Cialis in its liquids, and has raised the ire of the Food and Drug Administration. One liquid was called e-Cialis, a popular erectile dysfunction drug, and was displayed with photos of the real product, according to Ars Technica. A weight loss drug, whose brand was banned in Europe, was allegedly adapted into the liquid form as well, though FDA testing proved it instead contained the erectile dysfunction medication found in Viagra. The FDA sent a warning letter to HelloCig on Thursday. It urged the company to make the necessary changes to properly market their products and asked they comply with FDA regulations to continue selling any type of drug. HelloCig alleged they responded to the FDA in a statement sent to USA Today Saturday. “Our aim is to fully comply with all FDA regulations, both in letter and spirit," the statement read. The FDA also released a statement, written by FDA Commissioner Scott Gottlieb, on the illegal sale of these liquids on Thursday. “There are no e-liquid products approved to contain prescription drugs or any other medications that require a doctor’s supervision,” the statement read. “Prescription drugs are carefully evaluated and labeled to reflect the risks of the medications and their potential interactions with other medicines, and vaping active drug ingredients is an ineffective route of delivery and can be dangerous.” Gottlieb considers the e-cigarette usage among teenagers an epidemic, he clarified in a statement last [...]

2018-10-15T14:38:04-07:00October, 2018|Oral Cancer News|

Youth vaping has soared in 2018, new data show

Source: www.wsj.com Authors: Betsy McKay and Jennifer Maloney Number of high schoolers who used e-cigarettes in the past 30 days has risen some 75% in 2018 Teen use of e-cigarettes has soared this year, according to new research conducted in 2018 that suggest fast-changing youth habits will pose a challenge for public-health officials, schools and parents. The number of high-school students who used e-cigarettes in the past 30 days has risen roughly 75% since last year, according to a person who has seen new preliminary federal data. That would equate to about three million, or about 20% of high-school students, up from 1.73 million, or 11.7% of high-school students in the most recently published federal numbers from 2017. Nearly a third of 13-to-18-year-olds who responded to a separate survey conducted by The Wall Street Journal with research firm Mercury Analytics said they currently vape. The new numbers offer a rare look at evolving teen vaping habits. Sales of e-cigarettes are expected nearly to double this year over 2017, and researchers have wondered how much of that increase is because of teen use. But there can be a long lag time between the collection of data and public reports. Most of the teens who vape said they are doing it for reasons other than to quit smoking, according to the Journal’s survey conducted in 49 states in May. More than half said they do it because they like the flavors that e-cigarette liquids come in and they think vaping is fun. [...]

2018-09-21T08:57:52-07:00September, 2018|Oral Cancer News|

E-cigarettes ‘could give you mouth cancer by damaging your DNA’

Source: metro.co.uk Author: Zoe Drewett Researchers say vaping could lead to an increased risk of developing mouth cancer. A study carried out by the American Chemical Society found evidence to suggest using e-cigarettes raises the level of DNA-damaging compounds in the mouth. If cells in the body are unable to repair the DNA damage after vaping, the risk of cancer can increase, the study claims. The long-term effects of e-cigarettes are not yet known but researchers say they should be investigated further (Picture: PA) The researchers admit the long-term health effects of using electronic cigarettes are still unknown. Researcher Dr Romel Dator said: ‘We want to characterize the chemicals that vapers are exposed to, as well as any DNA damage they may cause.’ Since they were introduced in 2004, e-cigarettes have been marketed as a safer alternative to smoking. But the team carrying out the study claim genetic material in the oral cells of people who vape could be altered by toxic chemicals. E-cigarettes work by heating a liquid – which usually contains nicotine – into an aerosol that the user inhales. It is often flavoured to taste like fruit, chocolate or bubblegum. ‘It’s clear that more carcinogens arise from the combustion of tobacco in regular cigarettes than from the vapor of e-cigarettes,’ Silvia Balbo, the project’s lead investigator said. ‘However, we don’t really know the impact of inhaling the combination of compounds produced by this device. ‘Just because the threats are different doesn’t mean that e-cigarettes are completely [...]

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