A cancer on the rise, and the vaccine too late for Gen X

Source: www.cnn.comAuthor: Martha Shade  (CNN)The vaccine given to prevent cervical cancer in women could end up saving men's lives, too. Evidence is mounting that the HPV vaccine is also effective in preventing other HPV-related cancers, including those of the head and neck. Although most people who get HPV do not develop cancer, rates of HPV-related head and neck cancers are dramatically rising for men aged 40 to 50, according to Dr. Maura L. Gillison, the Jeg Coughlin Chair of Cancer Research at the Ohio State University Comprehensive Cancer Center. When Gillison recently gave a presentation showing the increasing rate of HPV-related head and neck cancer among men, her audience was shocked. "I've never shown a slide where the audience gasps," she said. Related: Yes, oral sex can lead to cancer "The risk of getting this cancer is strongly related to when you were born. If you are currently a 40- to 45-year-old man, your risk of getting this cancer is dramatically higher than a 40- to 45-year-old man three or four decades ago," Gillison said. Today's 40- to 50-year-old men have had more sexual partners and have engaged in more oral sex than previous generations, according to experts, significantly raising their risk of an HPV-related head and neck cancer. Actor Michael Douglas made headlines in 2013 when he announced he was battling an HPV-related cancer and that he got it from performing oral sex. Douglas was 68 when he was diagnosed, but many of the men being diagnosed with these [...]

2015-11-05T11:21:19-07:00November, 2015|OCF In The News, Oral Cancer News|

CDC says graphic anti-smoking ads work, more on way

Source: USA Today The federal government says its graphic ad campaign showing diseased smokers has been such a success that it is planning another round next year to nudge more Americans to kick the habit. The ads, which ran for 12 weeks in spring and early summer, aimed to get 500,000 people to try to quit and 50,000 to kick the habit long-term. "The initial results suggest the impact will be even greater than that," says Thomas Frieden, director of the Centers for Disease Control and Prevention, which spearheaded the $54 million campaign. The ads showed real Americans talking about how smoking caused their paralysis, lung removal and amputations. He says it's the first time the U.S. government has paid for anti-smoking ads, although some media ran them free. The CDC doesn't have a tally yet on how many people actually tried to quit, but it says the ads generated 192,000 extra calls — more than double the usual volume — to its national toll-free quit line, 800-QUIT-NOW, and 417,000 new visitors to smokefree.gov, its website offering cessation tips. That's triple the site's previous traffic. "We do plan to do another (campaign) next year," Frieden says, adding that he has no details yet on the ads or their timing. He says the amount the CDC spent this year is a pittance compared with the $10 billion the tobacco industry spends annually to market its products. The nation's two largest tobacco companies, Philip Morris USA and R.J. Reynolds Tobacco Company, declined [...]

2012-08-07T10:39:19-07:00August, 2012|Oral Cancer News|

Vaccination rates higher in states requiring them in middle school

Source: LA Times States that require vaccination for pertussis, meningitis and tetanus for admission to middle school have a higher vaccination rate than states that do not, but the rate is not nearly as high as one might expect from such a requirement, researchers reported Monday. States that required only that educational materials be sent home for those vaccines and the human papilloma virus (HPV) vaccine showed no improvement in vaccination rates. Vaccines for tetanus and pertussis are typically given during childhood, but the effects can diminish over time and a booster shot is recommended in early adolescence. The meningitis and HPV vaccines typically are given in adolescence. Concern has been spreading about low vaccination rates because of recent outbreaks of pertussis, commonly called whooping cough, in California and Washington.  Some parents refuse to have their children vaccinated because of groundless fears about vaccine side effects -- particularly the now-refuted link to autism -- but others simply find that it is easier to express "philosophical opposition" to the vaccines rather than take their children for the shots. But these unvaccinated children serve as a natural reservoir for the diseases, enhancing their spread, particularly to those who are too old or immune-impaired to receive the vaccines themselves. Thirty-two states required middle school vaccination with either the tetanus/diptheria (Td) vaccine or the tetanus/diptheria/acellular pertussis (TdaP) vaccine when the survey was performed in 2008-09. Fourteen of those specifically required the TdaP vaccine. None required that educational materials about those vaccines be sent home. [...]

2012-05-08T16:49:50-07:00May, 2012|Oral Cancer News|

HPV Vaccine Recommendation for Boys Viewed as Necessary

Source: OncLive.com  As the incidence of head and neck cancers linked to the human papillomavirus (HPV) continues to rise, a federal advisory panel has recommended that all 11- and 12-year-old boys be vaccinated against the virus, igniting further controversy in an area where acceptance of a public health policy has been slow. The recommendation from the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention (CDC) would expand the use of the vaccine beyond the original target population of 11- and 12-year-old girls for whom it is recommended as protection against cervical cancer. Ezra E. W. Cohen, MD, firmly supports the latest recommendation. “It’s the right move by the CDC,” he said in an interview. “I think it’s a long time coming.” Cohen said that the fact that the original recommendations targeted cervical cancer created a cultural perception that the vaccine was only intended for girls. Yet the HPV virus affects men as well. According to the CDC, HPV is associated with about 18,000 cancers in women and 7000 cancers in men each year. Overall, the incidence of HPV-positive oropharynx cancers increased by 225% between 1988 and 2004, according to National Cancer Institute research. There were an estimated 6700 cases of HPV-positive oropharynx cancers in 2010, up from 4000 to 4500 in 2004. Cohen said he believes such numbers are going to continue to rise. Even by taking proactive steps in 2011, the vaccine is only intended for children and young adults. HPV that is already [...]

2012-04-18T10:05:13-07:00April, 2012|Oral Cancer News|

HPV Vaccine May Prevent Recurrence of Precancerous Conditions

Source: abcnews.com The human papillomavirus (HPV) vaccine has been touted as a way to prevent cervical cancer and genital warts, but a new study suggests the vaccine may also prevent women diagnosed with precancers from developing recurrences. Researchers randomly assigned more than 1,350 women diagnosed with genital warts or certain precancerous conditions to receive either three injections of the HPV vaccine or a placebo. The women were followed for about four years. Women who received the vaccine had 46.2 percent lower risk of developing another HPV-related disease after treatment for their genital warts or their precancerous condition. Typically, women treated for these types of conditions are at risk for subsequent disease later, but the study offers evidence that "vaccination offered substantial benefit" in terms of lowering that risk, wrote the international team of authors, led by Elmar Joura, an associate professor at the University of Vienna in Austria. Experts not involved with the research told ABC News that the research is significant because it suggests for the first time that the HPV vaccine may offer benefits beyond prevention. "We always thought about the vaccine from the prevention, and this suggests it can lower the risk of developing a second episode of disease," said Dr. Anna Giuliano, director of the Center for Infection Research in Cancer at the Moffitt Cancer Center in Tampa. Giuliano cited another study published online in January that found the HPV vaccine reduces the recurrence of abnormal anal cell growths in men. "We're now seeing a pattern [...]

2012-04-17T10:16:45-07:00April, 2012|Oral Cancer News|

Young Girls More Likely to Report Side Effects after HPV Vaccine

Source: Therapeutics Daily PORTLAND, Ore., April 3, 2012 /PRNewswire/ -- Younger girls are more likely than adult women to report side effects after receiving Gardasil, the human papillomavirus vaccine. The side effects are non-serious and similar to those associated with other vaccines, according to a new study funded by the Centers for Disease Control and Prevention and published in the Journal of Women's Health. As part of an ongoing study and evaluation of this relatively new vaccine, researchers surveyed 899 girls and young women (ages 11-26) within two weeks after they received the Gardasil vaccine injection in the upper arm. The survey, which took place in 2008, also found that while most girls and young women did know that the vaccine can prevent cervical cancer, and that three doses are recommended, many didn't know that the vaccine can also prevent genital warts and abnormal pap smears. "Gardasil is an important cancer-prevention vaccine, but too few girls are getting it. Our study found that young girls do have some knowledge about the vaccine, but they need to know more. If these girls and their parents know what to expect, they will likely be less afraid of getting the vaccine," said study lead author Allison Naleway, PhD, a senior investigator with the Kaiser Permanente Center for Health Research in Portland, Ore. Since 2006, the CDC has recommended Gardasil for girls ages 11-12, and for older girls and women (ages 13-26) who did not receive the vaccine when they were younger. The CDC [...]

2012-04-11T09:43:23-07:00April, 2012|Oral Cancer News|

Tobacco Makers Must List Ingredients, Prove Safety Claims

Source: Businessweek.com Tobacco companies will have to begin reporting the amount of unsafe chemicals in their products and prove their so-called lower-risk alternatives to smoking such as snuff are actually safer, U.S. regulators said. The Food and Drug Administration moved today to implement pieces of a 2009 law giving the agency the authority to regulate tobacco products. The FDA released preliminary guidelines for the industry that it says can educate consumers on exactly what is in cigarettes, such as ammonia and formaldehyde, and police claims that certain tobacco products may be safer than others. The agency will share information on chemical amounts with the public within a year, Lawrence Deyton, director of the FDA’s Center for Tobacco Products, said in a telephone call with reporters. On the issue of less-risky tobacco items, the draft guidelines set up two categories: one with a higher evidence standard that lets companies claim less harm than cigarettes; and another with a lower standard that permits companies to market products as reducing exposure to unsafe ingredients. “We are forging new territory to ensure that tobacco companies provide accurate information and do not mislead American consumers,” FDA Commissioner Margaret Hamburg said in a statement. “We are committed to stopping such practices that may cause people to start or continue using tobacco products that could lead to preventable disease and death.” 93 Chemicals The FDA released a list of 93 chemicals that tobacco makers would have to report the quantity of in their products. The FDA is studying [...]

2012-04-02T09:56:47-07:00April, 2012|Oral Cancer News|

Maura L. Gillison, M.D., Ph.D., Receives AACR’s Richard and Hinda Rosenthal Memorial Award

Source: AACR News CHICAGO — The American Association for Cancer Research will award Maura L. Gillison, M.D., Ph.D., with the 36th Annual AACR Richard and Hinda Rosenthal Memorial Award during the AACR Annual Meeting 2012, held here March 31 – April 4. Gillison is receiving this award in recognition of her significant contributions to the understanding of the role of human papillomavirus (HPV) in head and neck cancers. Gillison’s award lecture, “Clinical implications of HPV in head and neck cancers,” will take place at 10 a.m. CT on Wednesday, April 4 in room S100 of the McCormick Place Convention Center. “It is an honor to be the recipient of this award,” said Gillison. “Our team strives to generate data that will improve the lives of individuals affected by head and neck cancers, and this is a wonderful validation that we are on the right track.” This award is designed to provide incentive to young investigators early in their careers. It was established in 1977 by the AACR and the Rosenthal Family Foundation to recognize research that has made, or promises to make, a notable contribution to improved clinical care in the field of cancer. Gillison is a professor of medicine, epidemiology and otolaryngology and the Jeg Coughlin Chair of Cancer Research at Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute in Columbus, Ohio. She is also adjunct faculty at The Johns Hopkins University School of Medicine, in Baltimore, Md. Her [...]

2012-03-23T09:31:04-07:00March, 2012|Oral Cancer News|

Oral Sex Cancer Virus More Common in Men Than Women, Study Finds

Source: Bloomberg.com About 10 percent of men and 3.6 percent of women are orally infected with human papillomavirus, which is acquired through oral sex and can cause cancer. There are two peaks in the age people are infected -- 30 to 34 and 60 to 64, according to the study published today in the Journal of the American Medical Association. The virus is linked to throat cancer, and is becoming a more common cause of the disease as Americans quit smoking. The virus, called HPV, is the most-common sexually transmitted virus in the U.S., where half the population will be infected at some time in their lives, according to the Centers for Disease Control and Prevention. It is known to cause cervical, vulvar, vaginal, penile and anal cancer. The higher HPV infection rate in men explains why their head and neck cancer rates are greater, said Maura Gillison, a professor at the Ohio State University College of Medicine in Columbus. “This provides pretty strong evidence that the higher infection rate is the reason why,” said Gillison, the study’s lead author, in a telephone interview. “This is a jumping board for additional research.” Besides sex, other demographics associated with oral HPV infection include age, lifetime number of sex partners, and the number of cigarettes smoked each day. The research is the first population-based study to examine how many men and women were infected, Gillison said. Existing Vaccines Though Merck & Co.’s Gardasil and GlaxoSmithKline Plc (GSK)’s Cervarix target genital HPV, it’s [...]

2012-01-26T10:10:18-07:00January, 2012|Oral Cancer News|

The one thing Rick Perry did right: A shot that stops cancer, the politics of sex and HPV prevention

Source: CultureMap.com I don’t like Rick Perry — I never voted for him and worked actively to try to oust him — but in 2006 he tried to do something good for young girls in Texas. He tried to mandate vaccinations for sixth grade girls with a drug that prevented HPV (Human Papilloma Virus), the devil behind cervical cancer. This virus is responsible for the deaths of 4,000 young women each year in the United States. When Perry announced his mandate, the shit hit the fan and his conservative base (which is most of the state) went ballistic. The social conservatives objected to the vaccine as an infringement on parental rights, and small government conservatives were alarmed at Perry’s aggressive use of executive power. Needless to say, Perry backed off, and the vaccine was off to a miserable start. Six years later, fewer than 33 percent of girls ages 11 to 26 have received all three doses of the HPV vaccine, and Perry is still paying a political price for it. ​Not just for girls Well, it now appears that boys aren’t “immune” from HPV’s effects. After all, girls have to get infected from somewhere, right? Doctors have observed that young men were getting throat cancers that were usually seen in older, tobacco-using men. Also, there was an increase in anal cancers. Who do you think the culprit behind this was? HPV. It turns out that HPV is the most common sexually transmitted disease: between 75 and 80 percent of [...]

2011-12-02T12:39:52-07:00December, 2011|Oral Cancer News|
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