HPV Linked to Throat Cancer
5/10/2007 web-based article Salynn Boyles WebMD.com Oral Sex Is Major Risk Factor HPV, the virus that causes cervical cancer, is also linked to throat cancer, and oral sex is a major risk factor for both men and women, new research shows. Having multiple oral sex partners topped the list of practices associated with an increased risk of developing oropharyngeal cancer, according to the study published in the May 10 issue of The New England Journal of Medicine. People in the study who reported having a history of six or more oral sex partners were three times as likely to develop the cancer as people who reported that they had never had oral sex. In looking at patients with tumors that were positive for a particular strain of HPV already well-linked to cervical cancer, six or more oral sex partners increased risk for throat cancer by eightfold. And those who showed evidence of a prior oral infection with human papillomavirus (HPV) were 32 times more likely to develop the cancer. Oral sex seemed to be the main mode of transmission for oral HPV, although the researchers note that transmission from mouth to mouth contact couldn't be excluded. The new study shows that oral HPV infection is linked to head and neck cancer regardless of two other known risk factors: heavy tobacco and alcohol use. But longtime HPV researcher Maura L. Gillison, MD, PhD, of Johns Hopkins University in Baltimore, says the findings should not be seen as cause for undue alarm. [...]