{"id":6933,"date":"2009-10-13T13:24:48","date_gmt":"2009-10-13T20:24:48","guid":{"rendered":"http:\/\/oralcancernews.org\/wp\/?p=6933"},"modified":"2009-10-13T13:24:48","modified_gmt":"2009-10-13T20:24:48","slug":"ct-characteristics-of-resolving-ground-glass-opacities-in-a-lung-cancer-screening-programme","status":"publish","type":"post","link":"https:\/\/oralcancernews.org\/wp\/ct-characteristics-of-resolving-ground-glass-opacities-in-a-lung-cancer-screening-programme\/","title":{"rendered":"CT characteristics of resolving ground-glass opacities in a lung cancer screening programme"},"content":{"rendered":"

Source: Eur J Radiol<\/em>, October 3, 2009
\nAuthor: L Felix et al.<\/p>\n

Purpose:
\nThis study aimed at evaluating the computed tomography (CT) characteristics of resolving localized ground-glass opacities (GGOs) in a screening programme for lung cancer. <\/p>\n

Material and Methods:
\n280 patients at high-risk for lung cancer (221 men, 59 women; mean age, 58.6 years), divided into four groups (lung cancer history (n=83), head and neck cancer history (n=63), symptomatic (n=88) and asymptomatic (n=46) cigarette smokers), were included in a prospective trial with annual low-dose CT for lung cancer screening. We retrospectively reviewed all localized GGOs, analyzed the CT characteristics on initial CT scans and changes during follow-up (median 29.1 months). Variables associated with resolution of GGOs were tested using chi-square or Mann-Whitney tests. <\/p>\n

Results:
\nA total of 75 GGOs were detected in 37 patients; 54.7% were present at baseline and 45.3% appeared on annual CT. During follow-up, 56.2% persisted and 43.8% disappeared. The resolving localized GGOs were significantly more often lobular GGOs (p=0.006), polygonal in shape (p=0.02), mixed (p=0.003) and larger (p<0.0001) than non-resolving localized GGOs. <\/p>\n

Conclusion:
\nLocalized GGOs are frequent and many disappeared on follow-up. CT characteristics of resolving GGOs show significant differences compared to persistent ones. This study emphasizes the importance of short-term CT follow-up in subjects with localized GGOs.<\/p>\n

Authors:
\nL Felix, G Serra-Tosio, S Lantuejoul, J F Timsit, D Moro-Sibilot, C Brambilla, and G R Ferretti<\/p>\n

Authors’ affiliation:
\nClinique Universitaire de Radiologie et Imagerie M\u00e9dicale, Universit\u00e9 Grenoble I, CHU Grenoble, France<\/p>\n","protected":false},"excerpt":{"rendered":"

Source: Eur J Radiol, October 3, 2009 Author: L Felix et al. Purpose: This study aimed at evaluating the computed tomography (CT) characteristics of resolving localized ground-glass opacities (GGOs) in a screening programme for lung cancer. Material and Methods: 280 patients at high-risk for lung cancer (221 men, 59 women; mean age, 58.6 years), divided into four groups (lung cancer history (n=83), head and neck cancer history (n=63), symptomatic (n=88) and asymptomatic (n=46) cigarette smokers), were included in a prospective trial with annual low-dose CT for lung cancer screening. We retrospectively reviewed all localized GGOs, analyzed the CT characteristics on initial CT scans and changes during follow-up (median 29.1 months). Variables associated with resolution of GGOs were tested using chi-square or Mann-Whitney tests. Results: A total of 75 GGOs were detected in 37 patients; 54.7% were present at baseline and 45.3% appeared on annual CT. During follow-up, 56.2% persisted and 43.8% disappeared. The resolving localized GGOs were significantly more often lobular GGOs (p=0.006), polygonal in shape (p=0.02), mixed (p=0.003) and larger (p<0.0001) than non-resolving localized GGOs. Conclusion: Localized GGOs are frequent and many disappeared on follow-up. CT characteristics of resolving GGOs show significant differences compared to persistent ones. This study emphasizes the importance of short-term CT follow-up in subjects with localized GGOs. Authors: L Felix, G Serra-Tosio, S Lantuejoul, J F Timsit, D Moro-Sibilot, C Brambilla, and G R Ferretti Authors’ affiliation: Clinique Universitaire de Radiologie et Imagerie M\u00e9dicale, Universit\u00e9 Grenoble I, CHU Grenoble, France<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[370,371,1543],"class_list":["post-6933","post","type-post","status-publish","format-standard","hentry","category-oral_cancer_news","tag-computed-tomography","tag-ct","tag-ground-glass-opacities"],"_links":{"self":[{"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/posts\/6933","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/comments?post=6933"}],"version-history":[{"count":4,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/posts\/6933\/revisions"}],"predecessor-version":[{"id":6937,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/posts\/6933\/revisions\/6937"}],"wp:attachment":[{"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/media?parent=6933"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/categories?post=6933"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/tags?post=6933"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}