{"id":6138,"date":"2009-06-30T15:48:22","date_gmt":"2009-06-30T22:48:22","guid":{"rendered":"http:\/\/oralcancernews.org\/wp\/?p=6138"},"modified":"2009-06-30T16:01:21","modified_gmt":"2009-06-30T23:01:21","slug":"u-s-scientists-say-lilly-erbitux-cancer-drug-not-worth-price","status":"publish","type":"post","link":"https:\/\/oralcancernews.org\/wp\/u-s-scientists-say-lilly-erbitux-cancer-drug-not-worth-price\/","title":{"rendered":"U.S. scientists say Lilly Erbitux cancer drug not worth price"},"content":{"rendered":"<p><strong>Source: Bloomberg<\/strong><br \/>\n<strong>Author: Lisa Rapaport<\/strong><\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\"><strong><br \/>\n<\/strong>\n<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\"><a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwQuoteShort( this, 'LLY:US' ))\" href=\"http:\/\/www.bloomberg.com\/apps\/quote?ticker=LLY%3AUS\">Eli Lilly<\/a> &amp; Co.\u2019s tumor-fighter Erbitux doesn\u2019t prolong lung cancer patients\u2019 lives enough to justify its $80,000 cost, U.S. scientists said in commentary published today.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">Erbitux added to other cancer drugs extends survival about 1.2 months more than chemotherapy alone, making the price too high for a \u201cmarginal benefit,\u201d commentary in the\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwOpenWebSite( this ))\" href=\"http:\/\/jnci.oxfordjournals.org\/\" target=\"_blank\">Journal of the National Cancer Institute<\/a> said. Erbitux, which Lilly markets with\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwQuoteShort( this, 'BMY:US' ))\" href=\"http:\/\/www.bloomberg.com\/apps\/quote?ticker=BMY%3AUS\">Bristol-Myers Squibb Co.,<\/a> generated $1.3 billion last year as treatment approved for other malignancies.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">The high price of some of the newest cancer medicines are coming under scrutiny as part of an effort by lawmakers and health officials to rein in overall medical costs. President\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwSearchNews( this ))\" href=\"http:\/\/search.bloomberg.com\/search?q=Barack+Obama&amp;site=wnews&amp;client=wnews&amp;proxystylesheet=wnews&amp;output=xml_no_dtd&amp;ie=UTF-8&amp;oe=UTF-8&amp;filter=p&amp;getfields=wnnis&amp;sort=date:D:S:d1\">Barack Obama<\/a> has set aside $1.1 billion in the U.S. economic stimulus bill to study the comparative effectiveness of treatments for cancer and other diseases.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">\u201cWe must avoid the temptation to tell a patient that a new drug is available if there is little evidence that it will work better than established drugs that could be offered at a miniscule fraction of the cost,\u201d wrote the commentators,\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwOpenWebSite( this ))\" href=\"http:\/\/ccr.cancer.gov\/staff\/staff.asp?profileid=5729\" target=\"_blank\">Tito Fojo<\/a> with the National Cancer Institute and\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwOpenWebSite( this ))\" href=\"http:\/\/www.cc.nih.gov\/about\/SeniorStaff\/christine_grady.html\" target=\"_blank\">Christine Grady<\/a> at the National Institutes of Health.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">Lilly, of Indianapolis, and marketing partner\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwQuoteShort( this, 'BMY:US' ))\" href=\"http:\/\/www.bloomberg.com\/apps\/quote?ticker=BMY%3AUS\">Bristol- Myers<\/a>, of New York, withdrew an application to extend the Erbitux\u2019s use to lung tumors in February after the Food and Drug Administration questioned differences in American and European versions of the treatment.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">$10,000 a Month<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">The authors projected that Erbitux costs $80,000 based on a typical course of treatment for lung tumors, 18 weeks. If all 550,000 U.S. patients who die of cancer each year took 12 months of Erbitux, the total cost would be $440 billion, 100 times the annual budget of the National Cancer Institute, the authors said.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">Bristol-Myers estimated Erbitux\u2019s cost to be lower, at about $10,000 a month, according to company spokesman Brian Henry. The drug is approved to treat head, neck and colon cancer. A Lilly spokeswoman referred questions to Bristol-Myers.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">\u201cErbitux isn\u2019t indicated for all cancer patients, nor would all cancer patients for which Erbitux is indicated necessarily receive the medicine for one year,\u201d Henry said in an e-mailed statement.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">Lilly gained Erbitux in its $6.5 billion purchase of ImClone Systems Inc. last year. German drugmaker\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwQuoteShort( this, 'MRK:GR' ))\" href=\"http:\/\/www.bloomberg.com\/apps\/quote?ticker=MRK%3AGR\">Merck<\/a> KGaA markets Erbitux outside the U.S.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">Cancer medicines are the best-selling and fastest-growing group of drugs in the U.S., and sales will surge 12 to 15 percent each year to top $75 billion by 2012, according to\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwQuoteShort( this, 'RX:US' ))\" href=\"http:\/\/www.bloomberg.com\/apps\/quote?ticker=RX%3AUS\">IMS Health<\/a> Inc., a pharmaceutical industry research company in Norwalk, Connecticut.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">About 220,000 people will be diagnosed with\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwOpenWebSite( this ))\" href=\"http:\/\/www.cancer.gov\/cancertopics\/types\/lung\" target=\"_blank\">lung cancer<\/a> in the U.S. this year, and 160,000 will die, according to the National Cancer Institute.<\/p>\n<p style=\"margin-top: 8px; margin-right: 0px; margin-bottom: 8px; margin-left: 0px; padding: 0px;\">To contact the reporter on this story:\u00a0<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwSearchNews( this ))\" href=\"http:\/\/search.bloomberg.com\/search?q=Lisa+Rapaport&amp;site=wnews&amp;client=wnews&amp;proxystylesheet=wnews&amp;output=xml_no_dtd&amp;ie=UTF-8&amp;oe=UTF-8&amp;filter=p&amp;getfields=wnnis&amp;sort=date:D:S:d1\">Lisa Rapaport<\/a> in New York at<a style=\"color: #006b99; font-weight: bold; text-decoration: none;\" onmouseover=\"return escape( popwSendEmail( this ))\" href=\"mailto:Lrapaport1@bloomberg.net\">Lrapaport1@bloomberg.net<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Source: Bloomberg Author: Lisa Rapaport Eli Lilly &amp; Co.\u2019s tumor-fighter Erbitux doesn\u2019t prolong lung cancer patients\u2019 lives enough to justify its $80,000 cost, U.S. scientists said in commentary published today. Erbitux added to other cancer drugs extends survival about 1.2 months more than chemotherapy alone, making the price too high for a \u201cmarginal benefit,\u201d commentary in the\u00a0Journal of the National Cancer Institute said. Erbitux, which Lilly markets with\u00a0Bristol-Myers Squibb Co., generated $1.3 billion last year as treatment approved for other malignancies. The high price of some of the newest cancer medicines are coming under scrutiny as part of an effort by lawmakers and health officials to rein in overall medical costs. President\u00a0Barack Obama has set aside $1.1 billion in the U.S. economic stimulus bill to study the comparative effectiveness of treatments for cancer and other diseases. \u201cWe must avoid the temptation to tell a patient that a new drug is available if there is little evidence that it will work better than established drugs that could be offered at a miniscule fraction of the cost,\u201d wrote the commentators,\u00a0Tito Fojo with the National Cancer Institute and\u00a0Christine Grady at the National Institutes of Health. Lilly, of Indianapolis, and marketing partner\u00a0Bristol- Myers, of New York, withdrew an application to extend the Erbitux\u2019s use to lung tumors in February after the Food and Drug Administration questioned differences in American and European versions of the treatment. $10,000 a Month The authors projected that Erbitux costs $80,000 based on a typical course of treatment for lung  [&#8230;]<\/p>\n","protected":false},"author":41,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[822,1138,209,245,139,1139,1137,798,619,34],"class_list":["post-6138","post","type-post","status-publish","format-standard","hentry","category-oral_cancer_news","tag-anal-cancer","tag-bristol-myers-squibb-co","tag-cancer","tag-erbitux","tag-fda","tag-ims-health","tag-journal-of-the-national-cancer-institute","tag-lung-cancer","tag-national-cancer-institute","tag-oral-cancer"],"_links":{"self":[{"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/posts\/6138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/users\/41"}],"replies":[{"embeddable":true,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/comments?post=6138"}],"version-history":[{"count":2,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/posts\/6138\/revisions"}],"predecessor-version":[{"id":6141,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/posts\/6138\/revisions\/6141"}],"wp:attachment":[{"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/media?parent=6138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/categories?post=6138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/oralcancernews.org\/wp\/wp-json\/wp\/v2\/tags?post=6138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}