Source: EH News Bureau
Author: Staff

GlaxoSmithKline Pharmaceuticals Limited (GSK) recently shared the results of three recently published clinical studies, conducted for its cervical cancer vaccine—Cervarix. Said Dr Hasit Joshipura, Vice President, South Asia and Managing Director, GSK India, “The findings confirmed that the vaccine offers protection against five of the most common cancer-causing virus types, generates significantly higher immune response compared to the other available vaccine Gardasil and provides high and sustained antibody levels for at least 7.3 years till date.”

The clinical studies involved 18,644 women and was published in The Lancet. The study confirmed that Cervarix is not only highly effective at protecting against the two most common cervical cancer-causing human papillomavirus (HPV) types, 16 and 18, but also provides additional cross-protection against HPV types 31, 33 and 45, the three most common cancer-causing virus types beyond 16 and 18. This additional efficacy could translate into approximately 11-16 per cent extra protection against cervical cancer over and above the protection afforded by efficacy against HPV 16 and 18 alone. In India, the same five HPV types are responsible for almost 90 per cent cervical cancer cases.

“These results amply demonstrate that preventive vaccination is one of the most effective methods of primary prevention of HPV infection, the necessary cause of cervical cancer. In tandem with screening tests, it is perfectly positioned to lend a decisive edge against this deadly cancer. Extending the scope of protection beyond types 16 and 18 will allow prevention of the vast majority of cases of cervical cancer in India. Preventive vaccination against cervical cancer has now come of age,” said Dr Neerja Bhatla, Additional Professor, Department of Obstetrics and Gynaecology, AIMS.