• 7/1/2006
  • Austin, TX
  • press release
  • Introgen Therapeutics, Inc

Introgen Therapeutics, Inc. will conduct a conference call on July 18, 2006 at 3:30 p.m. ET to discuss data regarding Introgen’s lead product ADVEXIN® presented at the annual meetings of the American Society of Gene Therapy (ASGT) and the American Society of Clinical Oncology (ASCO). A panel of clinical experts will discuss the importance of prognostic indicators of ADVEXIN efficacy associated with high response rates, locoregional disease control and increased survival identified in Introgen’s Phase 2 trials in patients with head and neck cancer.

The call will include detailed discussions of the significance and clinical application of biomarkers predictive of ADVEXIN efficacy. The identification of prognostic indicators of ADVEXIN activity complies with initiatives of regulatory agencies to identify biomarkers that can predict the patient populations most likely to benefit from a specific cancer therapy.

In blinded analyses performed by an independent testing laboratory, a molecular biomarker was identified that predicted patients most likely to benefit from ADVEXIN cancer therapy. This biomarker also identifies patients who are less likely to respond to standard cancer treatment. The predictive biomarkers correlated with statistically significant increases in survival, tumor response and loco-regional disease control following ADVEXIN therapy in clinical trials. The predictive use of biomarkers coincides with Food and Drug Administration as well as with National Cancer Institute initiatives on the use of biomarkers in the development of breakthrough cancer therapies.

In addition, Introgen will discuss the successful use of ADVEXIN for Li- Fraumeni Syndrome cancer, an inherited form of malignancy characterized by the loss of p53 tumor suppressor protection.

This call is also being web cast and can be accessed at Introgen’s web site at http://www.introgen.com . A web cast replay will be available for one week at http://www.introgen.com .

About Introgen Therapeutics, Inc.

Introgen Therapeutics, Inc. is a biopharmaceutical company focused on the discovery, development and commercialization of targeted molecular therapies for the treatment of cancer and other diseases. Introgen is developing molecular therapeutics, immunotherapies, vaccines and nano-particle therapies to treat a wide range of cancers using tumor suppressors and cytokines. Introgen maintains integrated research, development, manufacturing, clinical and regulatory departments and operates multiple manufacturing facilities including a commercial scale cGMP manufacturing facility.