• 7/1/2006
  • Memphis, TN
  • staff
  • CancerConsultants.com

ImClone Systems Incorporated has received FDA approval for their monoclonal antibody Erbitux (cetuximab) in the treatment of head and neck cancer. Erbitux is the first and only monoclonal antibody approved for the treatment of head and neck cancer.

The new indication includes the use of Erbitux in combination with radiation therapy for the treatment of locally or regionally advanced squamous cell carcinoma of the head and neck, or as a single agent in the treatment of metastatic or recurrence squamous cell carcinoma of the head and neck that has failed prior platinum-based therapy.

The prior indication for Erbitux was its use in combination with Camptosar® (irinotecan) for the treatment of metastatic colorectal cancer refractory to irinotecan-based therapy in EGFR-expressing cancers, and as a single agent for the treatment of EGFR-expressing metastatic colorectal cancer in patients who were not able to tolerate irinotecan therapy.