buy rosetta stone filipino microsoft office 2013 buy now windows 7 professional student discount
  • buy windows 7 family pack malaysia cheap office 2013 download cost of windows 7 starter
  • buy 2007 microsoft word product key download acrobat pro 9 buying adobe acrobat 9 standard viagra made in australia where to buy viagra in perth australia viagra from doctor australia
    viagra buy in melbourne safe viagra australia buy cheap viagra australia
    kamagra oral jelly comprar tadalafil online bestellen indische viagra generika
      metronidazole compresse allopurinol prezzo allopurinol costo
    comment acheter du viagra forum cialis 10mg viagra bij de apotheek

    The lack of evidence for PET or PET/CT surveillance of patients with treated lymphoma, colorectal cancer, and head and neck cancer: a systematic review

    Wed, Sep 4, 2013

    Oral Cancer News

    Source: jnm.snmjournals.org
    Authors: Kamal Patel et al

    PET and PET/CT are widely used for surveillance of patients after cancer treatments. We conducted a systematic review to assess the diagnostic accuracy and clinical impact of PET and PET/CT used for surveillance in several cancers.

    Methods: We searched MEDLINE and Cochrane Library databases from 1996 to March 2012 for English-language studies of PET or PET/CT used for surveillance of patients with lymphoma, colorectal cancer, or head and neck cancer. We included prospective or retrospective studies that reported test accuracy and comparative studies that assessed clinical impact.

    Results: Twelve studies met our inclusion criteria: 6 lymphoma (n = 767 patients), 2 colorectal cancer (n = 96), and 4 head and neck cancer (n = 194). All studies lacked a uniform definition of surveillance and scan protocols. Half the studies were retrospective, and a third were rated as low quality. The majority reported sensitivities and specificities in the range of 90%–100%, although several studies reported lower results. The only randomized controlled trial, a colorectal cancer study with 65 patients in the surveillance arm, reported earlier detection of recurrences with PET and suggested improved clinical outcomes.

    Conclusion: There is insufficient evidence to draw conclusions on the clinical impact of PET or PET/CT surveillance for these cancers. The lack of standard definitions for surveillance, heterogeneous scanning protocols, and inconsistencies in reporting test accuracy preclude making an informed judgment on the value of PET for this potential indication.

    Authors:
    Kamal Patel, Nira Hadar, Jounghee Lee, Barry A. Siegel, Bruce E. Hillner and Joseph Lau
    Source: Journal of Nuclear Medicine September 1, 2013 vol. 54 no. 9 1518-1527

    Print Friendly
    Be Sociable, Share!
    , , , ,

    Leave a Reply

    You must be logged in to post a comment.